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Items: 18


A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs.

Plante A, Shore DM, Morra G, Khelashvili G, Weinstein H.

Molecules. 2019 Jun 2;24(11). pii: E2097. doi: 10.3390/molecules24112097.


Intergroup emotional exchange: Ingroup guilt and outgroup anger increase resource allocation in trust games.

Shore DM, Rychlowska M, van der Schalk J, Parkinson B, Manstead ASR.

Emotion. 2019 Jun;19(4):605-616. doi: 10.1037/emo0000463. Epub 2018 Jul 2.


Interpersonal effects of strategic and spontaneous guilt communication in trust games.

Shore DM, Parkinson B.

Cogn Emot. 2018 Sep;32(6):1382-1390. doi: 10.1080/02699931.2017.1395728. Epub 2017 Oct 30.


Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction.

Lynch DL, Hurst DP, Shore DM, Pitman MC, Reggio PH.

Methods Enzymol. 2017;593:449-490. doi: 10.1016/bs.mie.2017.05.004. Epub 2017 Jul 4.


Abnormalities in early visual processes are linked to hypersociability and atypical evaluation of facial trustworthiness: An ERP study with Williams syndrome.

Shore DM, Ng R, Bellugi U, Mills DL.

Cogn Affect Behav Neurosci. 2017 Oct;17(5):1002-1017. doi: 10.3758/s13415-017-0528-6.


Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones.

Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP.

Bioorg Med Chem Lett. 2016 Apr 1;26(7):1827-1830. doi: 10.1016/j.bmcl.2016.02.030. Epub 2016 Feb 16.


The therapeutic potential of orphan GPCRs, GPR35 and GPR55.

Shore DM, Reggio PH.

Front Pharmacol. 2015 Apr 15;6:69. doi: 10.3389/fphar.2015.00069. eCollection 2015. Review.


(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.

Mahmoud MM, Olszewska T, Liu H, Shore DM, Hurst DP, Reggio PH, Lu D, Kendall DA.

Mol Pharmacol. 2015 Feb;87(2):197-206. doi: 10.1124/mol.114.095471. Epub 2014 Nov 19.


CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.

Lucchesi V, Hurst DP, Shore DM, Bertini S, Ehrmann BM, Allarà M, Lawrence L, Ligresti A, Minutolo F, Saccomanni G, Sharir H, Macchia M, Di Marzo V, Abood ME, Reggio PH, Manera C.

J Med Chem. 2014 Nov 13;57(21):8777-91. doi: 10.1021/jm500807e. Epub 2014 Oct 15.


Pregnenolone can protect the brain from cannabis intoxication.

Vallée M, Vitiello S, Bellocchio L, Hébert-Chatelain E, Monlezun S, Martin-Garcia E, Kasanetz F, Baillie GL, Panin F, Cathala A, Roullot-Lacarrière V, Fabre S, Hurst DP, Lynch DL, Shore DM, Deroche-Gamonet V, Spampinato U, Revest JM, Maldonado R, Reggio PH, Ross RA, Marsicano G, Piazza PV.

Science. 2014 Jan 3;343(6166):94-8. doi: 10.1126/science.1243985. Erratum in: Science. 2014 Feb 28;343(6174):969.


Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling.

Shore DM, Baillie GL, Hurst DH, Navas F 3rd, Seltzman HH, Marcu JP, Abood ME, Ross RA, Reggio PH.

J Biol Chem. 2014 Feb 28;289(9):5828-45. doi: 10.1074/jbc.M113.478495. Epub 2013 Dec 23.


Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.

Kotsikorou E, Sharir H, Shore DM, Hurst DP, Lynch DL, Madrigal KE, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak LS, Croatt MP, Abood ME, Reggio PH.

Biochemistry. 2013 Dec 31;52(52):9456-69. doi: 10.1021/bi4008885. Epub 2013 Dec 17.


Do social utility judgments influence attentional processing?

Shore DM, Heerey EA.

Cognition. 2013 Oct;129(1):114-22. doi: 10.1016/j.cognition.2013.06.011. Epub 2013 Jul 24.


Novel insights into CB1 cannabinoid receptor signaling: a key interaction identified between the extracellular-3 loop and transmembrane helix 2.

Marcu J, Shore DM, Kapur A, Trznadel M, Makriyannis A, Reggio PH, Abood ME.

J Pharmacol Exp Ther. 2013 May;345(2):189-97. doi: 10.1124/jpet.112.201046. Epub 2013 Feb 20.


Evaluation of a new 240-μm single-use holmium:YAG optical fiber for flexible ureteroscopy.

Khemees TA, Shore DM, Antiporda M, Teichman JM, Knudsen BE.

J Endourol. 2013 Apr;27(4):475-9. doi: 10.1089/end.2012.0513.


Appetitive motivational deficits in individuals with Parkinson's disease.

Shore DM, Rafal R, Parkinson JA.

Mov Disord. 2011 Aug 15;26(10):1887-92. doi: 10.1002/mds.23736. Epub 2011 Apr 25.


The value of genuine and polite smiles.

Shore DM, Heerey EA.

Emotion. 2011 Feb;11(1):169-74. doi: 10.1037/a0022601.


Prestenting improves ureteroscopic stone-free rates.

Rubenstein RA, Zhao LC, Loeb S, Shore DM, Nadler RB.

J Endourol. 2007 Nov;21(11):1277-80.


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