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Weight change and sulfonylurea therapy are related to 3 year change in microvascular function in people with type 2 diabetes.

Casanova F, Gooding KM, Shore AC, Adingupu DD, Mawson D, Ball C, Anning C, Aizawa K, Gates PE, Strain WD.

Diabetologia. 2020 Mar 17. doi: 10.1007/s00125-020-05125-4. [Epub ahead of print]


Linezolid resistance in Enterococcus faecium and Enterococcus faecalis from hospitalized patients in Ireland: high prevalence of the MDR genes optrA and poxtA in isolates with diverse genetic backgrounds.

Egan SA, Shore AC, O'Connell B, Brennan GI, Coleman DC.

J Antimicrob Chemother. 2020 Mar 4. pii: dkaa075. doi: 10.1093/jac/dkaa075. [Epub ahead of print]


Renal nitrate clearance in chronic kidney disease.

Williams JK, Smallwood MJ, Benjamin N, D'Souza RJ, Shore AC, Winyard PG, Gilchrist M.

Nitric Oxide. 2020 Apr 1;97:16-19. doi: 10.1016/j.niox.2020.01.011. Epub 2020 Jan 30.


A Mendelian Randomization Study Provides Evidence that Adiposity and Dyslipidemia Lead to Lower Urinary Albumin Creatinine Ratio, a Marker of Microvascular Function.

Casanova F, Wood AR, Yaghootkar H, Beaumont RN, Jones SE, Gooding KM, Aizawa K, Strain WD, Hattersley AT, Khan F, Shore AC, Frayling TM, Tyrrell J.

Diabetes. 2020 Jan 8. pii: db190862. doi: 10.2337/db19-0862. [Epub ahead of print]


Evolution and Global Transmission of a Multidrug-Resistant, Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from the Indian Subcontinent.

Steinig EJ, Duchene S, Robinson DA, Monecke S, Yokoyama M, Laabei M, Slickers P, Andersson P, Williamson D, Kearns A, Goering RV, Dickson E, Ehricht R, Ip M, O'Sullivan MVN, Coombs GW, Petersen A, Brennan G, Shore AC, Coleman DC, Pantosti A, de Lencastre H, Westh H, Kobayashi N, Heffernan H, Strommenger B, Layer F, Weber S, Aamot HV, Skakni L, Peacock SJ, Sarovich D, Harris S, Parkhill J, Massey RC, Holden MTG, Bentley SD, Tong SYC.

mBio. 2019 Nov 26;10(6). pii: e01105-19. doi: 10.1128/mBio.01105-19.


Reply: Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction.

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH.

Plast Reconstr Surg. 2019 Nov;144(5):935e-936e. doi: 10.1097/PRS.0000000000006125. No abstract available.


Rapid treatment of moderate to severe hypertension using a novel protocol in a single-centre, before and after interventional study.

Jordan AN, Anning C, Wilkes L, Ball C, Pamphilon N, Clark CE, Bellenger NG, Shore AC, Sharp ASP.

J Hum Hypertens. 2020 Feb;34(2):165-175. doi: 10.1038/s41371-019-0272-1. Epub 2019 Oct 23.


A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin-creatinine ratio.

Casanova F, Tyrrell J, Beaumont RN, Ji Y, Jones SE, Hattersley AT, Weedon MN, Murray A, Shore AC, Frayling TM, Wood AR.

Hum Mol Genet. 2019 Dec 15;28(24):4197-4207. doi: 10.1093/hmg/ddz243.


"Reply: Intra-operative tissue perfusion measurement by Laser Speckle Imaging (LSI): a potential aid for reducing post-operative complications in free flap breast reconstructions."

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH.

Plast Reconstr Surg. 2019 Aug 12. doi: 10.1097/PRS.0000000000006125. [Epub ahead of print] No abstract available.


Arterial wall shear rate response to reactive hyperaemia is markedly different between young and older humans.

Aizawa K, Ramalli A, Sbragi S, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C.

J Physiol. 2019 Aug;597(16):4151-4163. doi: 10.1113/JP278310. Epub 2019 Jul 15.


Locally delivered GLP-1 analogues liraglutide and exenatide enhance microvascular perfusion in individuals with and without type 2 diabetes.

Aung MM, Slade K, Freeman LAR, Kos K, Whatmore JL, Shore AC, Gooding KM.

Diabetologia. 2019 Sep;62(9):1701-1711. doi: 10.1007/s00125-019-4918-x. Epub 2019 Jun 16.


Letter to the Editor: The use of indocyanine green angiography in postmastectomy reconstruction: Do outcomes improve over time?

To C, Rees-Lee JE, Gush RJ, Cawrse NH, Shore AC, Wilson ADH.

J Plast Reconstr Aesthet Surg. 2019 Sep;72(9):1576-1606. doi: 10.1016/j.bjps.2019.05.007. Epub 2019 May 17. No abstract available.


Editorial: New Insights and Updates on the Molecular Epidemiology and Antimicrobial Resistance of MRSA in Humans in the Whole-Genome Sequencing Era.

Coleman DC, Shore AC, Goering RV, Monecke S.

Front Microbiol. 2019 Apr 3;10:637. doi: 10.3389/fmicb.2019.00637. eCollection 2019. No abstract available.


Stability of urinary albumin and creatinine after 12 months storage at -20 °C and -80 °C.

Chapman DP, Gooding KM, McDonald TJ, Shore AC.

Pract Lab Med. 2019 Mar 22;15:e00120. doi: 10.1016/j.plabm.2019.e00120. eCollection 2019 May.


A molecular epidemiological investigation of methicillin-susceptible Staphylococcus aureus causing bloodstream infections in Ireland, 2006-2017.

Deasy EC, Brennan GI, Tecklenborg SC, Umeh C, Coleman DC, Shore AC.

Eur J Clin Microbiol Infect Dis. 2019 May;38(5):927-936. doi: 10.1007/s10096-019-03523-0. Epub 2019 Mar 23.


Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction.

To C, Rees-Lee JE, Gush RJ, Gooding KM, Cawrse NH, Shore AC, Wilson ADH.

Plast Reconstr Surg. 2019 Feb;143(2):287e-292e. doi: 10.1097/PRS.0000000000005223.


A novel multidrug-resistant PVL-negative CC1-MRSA-IV clone emerging in Ireland and Germany likely originated in South-Eastern Europe.

Earls MR, Shore AC, Brennan GI, Simbeck A, Schneider-Brachert W, Vremerǎ T, Dorneanu OS, Slickers P, Ehricht R, Monecke S, Coleman DC.

Infect Genet Evol. 2019 Apr;69:117-126. doi: 10.1016/j.meegid.2019.01.021. Epub 2019 Jan 21.


Continuous Simultaneous Recording of Brachial Artery Distension and Wall Shear Rate: A New Boost for Flow-Mediated Vasodilation.

Ramalli A, Aizawa K, Shore AC, Morizzo C, Palombo C, Lenge M, Tortoli P.

IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Mar;66(3):463-471. doi: 10.1109/TUFFC.2018.2889111. Epub 2018 Dec 24.


Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: A nested, case-control study.

Natali A, Nesti L, Venturi E, Shore AC, Khan F, Gooding K, Gates PE, Looker HC, Dove F, Goncalves I, Persson M, Nilsson J; SUMMIT consortium.

Diabetes Obes Metab. 2019 Feb;21(2):412-416. doi: 10.1111/dom.13519. Epub 2018 Oct 2.


Molecular Typing of ST239-MRSA-III From Diverse Geographic Locations and the Evolution of the SCCmec III Element During Its Intercontinental Spread.

Monecke S, Slickers P, Gawlik D, Müller E, Reissig A, Ruppelt-Lorz A, Akpaka PE, Bandt D, Bes M, Boswihi SS, Coleman DC, Coombs GW, Dorneanu OS, Gostev VV, Ip M, Jamil B, Jatzwauk L, Narvaez M, Roberts R, Senok A, Shore AC, Sidorenko SV, Skakni L, Somily AM, Syed MA, Thürmer A, Udo EE, Vremerǎ T, Zurita J, Ehricht R.

Front Microbiol. 2018 Jul 6;9:1436. doi: 10.3389/fmicb.2018.01436. eCollection 2018.


Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study.

Shore AC, Colhoun HM, Natali A, Palombo C, Khan F, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, Gates PE, Looker H, Dove F, Belch J, Pinnola S, Venturi E, Kozakova M, Goncalves I, Kravic J, Björkbacka H, Nilsson J; SUMMIT Consortium.

Diabetes Care. 2018 Oct;41(10):2212-2219. doi: 10.2337/dc18-0185. Epub 2018 Jul 30.


Intra-Hospital, Inter-Hospital and Intercontinental Spread of ST78 MRSA From Two Neonatal Intensive Care Unit Outbreaks Established Using Whole-Genome Sequencing.

Earls MR, Coleman DC, Brennan GI, Fleming T, Monecke S, Slickers P, Ehricht R, Shore AC.

Front Microbiol. 2018 Jul 4;9:1485. doi: 10.3389/fmicb.2018.01485. eCollection 2018.


Molecular Characterization of Nasal Methicillin-Resistant Staphylococcus aureus Isolates Showing Increasing Prevalence of Mupirocin Resistance and Associated Multidrug Resistance following Attempted Decolonization.

Poovelikunnel TT, Budri PE, Shore AC, Coleman DC, Humphreys H, Fitzgerald-Hughes D.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00819-18. doi: 10.1128/AAC.00819-18. Print 2018 Sep.


Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry.

Gates PE, Gurung A, Mazzaro L, Aizawa K, Elyas S, Strain WD, Shore AC, Shandas R.

Ultrasound Med Biol. 2018 Jul;44(7):1392-1401. doi: 10.1016/j.ultrasmedbio.2018.02.013. Epub 2018 Apr 17.


Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture.

Weir-McCall JR, Brown L, Summersgill J, Talarczyk P, Bonnici-Mallia M, Chin SC, Khan F, Struthers AD, Sullivan F, Colhoun HM, Shore AC, Aizawa K, Groop L, Nilsson J, Cockcroft JR, McEniery CM, Wilkinson IB, Ben-Shlomo Y, Houston JG.

Hypertension. 2018 May;71(5):937-945. doi: 10.1161/HYPERTENSIONAHA.117.10620. Epub 2018 Mar 19.


Range Expansion and the Origin of USA300 North American Epidemic Methicillin-Resistant Staphylococcus aureus.

Challagundla L, Luo X, Tickler IA, Didelot X, Coleman DC, Shore AC, Coombs GW, Sordelli DO, Brown EL, Skov R, Larsen AR, Reyes J, Robledo IE, Vazquez GJ, Rivera R, Fey PD, Stevenson K, Wang SH, Kreiswirth BN, Mediavilla JR, Arias CA, Planet PJ, Nolan RL, Tenover FC, Goering RV, Robinson DA.

mBio. 2018 Jan 2;9(1). pii: e02016-17. doi: 10.1128/mBio.02016-17.


Dissemination of high-level mupirocin-resistant CC22-MRSA-IV in Saxony.

Monecke S, Ruppelt-Lorz A, Müller E, Reissig A, Thürmer A, Shore AC, Coleman DC, Ehricht R, Jatzwauk L.

GMS Hyg Infect Control. 2017 Nov 20;12:Doc19. doi: 10.3205/dgkh000304. eCollection 2017.


Novel multiresistance cfr plasmids in linezolid-resistant methicillin-resistant Staphylococcus epidermidis and vancomycin-resistant Enterococcus faecium (VRE) from a hospital outbreak: co-location of cfr and optrA in VRE.

Lazaris A, Coleman DC, Kearns AM, Pichon B, Kinnevey PM, Earls MR, Boyle B, O'Connell B, Brennan GI, Shore AC.

J Antimicrob Chemother. 2017 Dec 1;72(12):3252-3257. doi: 10.1093/jac/dkx292.


Brachial artery vasodilatory response and wall shear rate determined by multigate Doppler in a healthy young cohort.

Aizawa K, Sbragi S, Ramalli A, Tortoli P, Casanova F, Morizzo C, Thorn CE, Shore AC, Gates PE, Palombo C.

J Appl Physiol (1985). 2018 Jan 1;124(1):150-159. doi: 10.1152/japplphysiol.00310.2017. Epub 2017 Sep 21.


The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control.

Casanova F, Adingupu DD, Adams F, Gooding KM, Looker HC, Aizawa K, Dove F, Elyas S, Belch JJF, Gates PE, Littleford RC, Gilchrist M, Colhoun HM, Shore AC, Khan F, Strain WD.

Cardiovasc Diabetol. 2017 Sep 15;16(1):114. doi: 10.1186/s12933-017-0594-7.


Associations between interarm differences in blood pressure and cardiovascular disease outcomes: protocol for an individual patient data meta-analysis and development of a prognostic algorithm.

Clark CE, Boddy K, Warren FC, Taylor RS, Aboyans V, Cloutier L, McManus RJ, Shore AC, Campbell JL.

BMJ Open. 2017 Jul 2;7(6):e016844. doi: 10.1136/bmjopen-2017-016844.


Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging.

Gurung A, Gates PE, Mazzaro L, Fulford J, Zhang F, Barker AJ, Hertzberg J, Aizawa K, Strain WD, Elyas S, Shore AC, Shandas R.

Ultrasound Med Biol. 2017 Aug;43(8):1618-1627. doi: 10.1016/j.ultrasmedbio.2017.03.020. Epub 2017 May 10.


Relationship Between Urinary Nitrate Excretion and Blood Pressure in the InChianti Cohort.

Smallwood MJ, Ble A, Melzer D, Winyard PG, Benjamin N, Shore AC, Gilchrist M.

Am J Hypertens. 2017 Jul 1;30(7):707-712. doi: 10.1093/ajh/hpx035.


The recent emergence in hospitals of multidrug-resistant community-associated sequence type 1 and spa type t127 methicillin-resistant Staphylococcus aureus investigated by whole-genome sequencing: Implications for screening.

Earls MR, Kinnevey PM, Brennan GI, Lazaris A, Skally M, O'Connell B, Humphreys H, Shore AC, Coleman DC.

PLoS One. 2017 Apr 11;12(4):e0175542. doi: 10.1371/journal.pone.0175542. eCollection 2017.


Adipose tissue is influenced by hypoxia of obstructive sleep apnea syndrome independent of obesity.

Thorn CE, Knight B, Pastel E, McCulloch LJ, Patel B, Shore AC, Kos K.

Diabetes Metab. 2017 Jun;43(3):240-247. doi: 10.1016/j.diabet.2016.12.002. Epub 2017 Jan 26.


GLP-1 analogue-induced weight loss does not improve obesity-induced AT dysfunction.

Pastel E, McCulloch LJ, Ward R, Joshi S, Gooding KM, Shore AC, Kos K.

Clin Sci (Lond). 2017 Mar 1;131(5):343-353. doi: 10.1042/CS20160803. Epub 2017 Jan 3.


Diversity of Staphylococcus aureus Isolates in European Wildlife.

Monecke S, Gavier-Widén D, Hotzel H, Peters M, Guenther S, Lazaris A, Loncaric I, Müller E, Reissig A, Ruppelt-Lorz A, Shore AC, Walter B, Coleman DC, Ehricht R.

PLoS One. 2016 Dec 16;11(12):e0168433. doi: 10.1371/journal.pone.0168433. eCollection 2016.


Raman spectroscopy and multivariate analysis for the non invasive diagnosis of clinically inconclusive vulval lichen sclerosus.

Frost J, Ludeman L, Hillaby K, Gornall R, Lloyd G, Kendall C, Shore AC, Stone N.

Analyst. 2017 Apr 10;142(8):1200-1206. doi: 10.1039/c6an02009g.


Prevalence of systolic inter-arm differences in blood pressure for different primary care populations: systematic review and meta-analysis.

Clark CE, Taylor RS, Shore AC, Campbell JL.

Br J Gen Pract. 2016 Nov;66(652):e838-e847. Epub 2016 Oct 10. Review.


Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus.

Old OJ, Lloyd GR, Nallala J, Isabelle M, Almond LM, Shepherd NA, Kendall CA, Shore AC, Barr H, Stone N.

Analyst. 2017 Apr 10;142(8):1227-1234. doi: 10.1039/c6an01871h.


Microstructure and mechanics of human resistance arteries.

Bell JS, Adio AO, Pitt A, Hayman L, Thorn CE, Shore AC, Whatmore JL, Winlove CP.

Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1560-H1568. doi: 10.1152/ajpheart.00002.2016. Epub 2016 Sep 23.


Microalbuminuria could improve risk stratification in patients with TIA and minor stroke.

Elyas S, Shore AC, Kingwell H, Keenan S, Boxall L, Stewart J, James MA, Strain WD.

Ann Clin Transl Neurol. 2016 Jul 27;3(9):678-83. doi: 10.1002/acn3.289. eCollection 2016 Sep.


Reduced pro-inflammatory responses to Staphylococcus aureus bloodstream infection and low prevalence of enterotoxin genes in isolates from patients on haemodialysis.

McNicholas S, Fe Talento A, O'Gorman J, Hannan MM, Lynch M, Greene CM, Conlon PJ, Shore AC, Coleman DC, Humphreys H, Fitzgerald-Hughes D.

Eur J Clin Microbiol Infect Dis. 2017 Jan;36(1):33-42. doi: 10.1007/s10096-016-2767-9. Epub 2016 Sep 9.


Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes.

Gonçalves I, Edsfeldt A, Colhoun HM, Shore AC, Palombo C, Natali A, Fredrikson GN, Björkbacka H, Wigren M, Bengtsson E, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Gates P, Khan F, Looker HC, Adams F, Belch J, Pinnola S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J; SUMMIT consortium.

BMC Cardiovasc Disord. 2016 Sep 5;16(1):171. doi: 10.1186/s12872-016-0346-8.


In vitro activity of ceftaroline against mecC-positive MRSA isolates.

Armengol-Porta M, Tenorio-Abreu A, Bandt D, Coleman DC, Gavier-Widen D, Hotzel H, Kinnevey P, Lazaris A, Peters M, Rangstrup-Christensen L, Schlotter K, Shore AC, Ehricht R, Monecke S.

J Glob Antimicrob Resist. 2016 Jun;5:3-6. doi: 10.1016/j.jgar.2016.01.006. Epub 2016 Feb 26.


Effect of nitrate supplementation on hepatic blood flow and glucose homeostasis: a double-blind, placebo-controlled, randomized control trial.

Shepherd AI, Wilkerson DP, Fulford J, Winyard PG, Benjamin N, Shore AC, Gilchrist M.

Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G356-64. doi: 10.1152/ajpgi.00203.2016. Epub 2016 Jul 14.


Reactivity to low-flow as a potential determinant for brachial artery flow-mediated vasodilatation.

Aizawa K, Elyas S, Adingupu DD, Casanova F, Gooding KM, Strain WD, Shore AC, Gates PE.

Physiol Rep. 2016 Jun;4(12). pii: e12808. doi: 10.14814/phy2.12808.


Inter-arm blood pressure difference and mortality: a cohort study in an asymptomatic primary care population at elevated cardiovascular risk.

Clark CE, Taylor RS, Butcher I, Stewart MC, Price J, Fowkes FG, Shore AC, Campbell JL.

Br J Gen Pract. 2016 May;66(646):e297-308. doi: 10.3399/bjgp16X684949. Epub 2016 Apr 14.


The role of perfusion in the oxygen extraction capability of skin and skeletal muscle.

Thorn CE, Shore AC.

Am J Physiol Heart Circ Physiol. 2016 May 15;310(10):H1277-84. doi: 10.1152/ajpheart.00047.2016. Epub 2016 Mar 25.

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