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Items: 1 to 50 of 137

1.

Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Aβ1-40-injected mouse model of Alzheimer's disease.

Park J, Lee SY, Shon J, Kim K, Lee HJ, Kim KA, Lee BY, Oh SH, Kim NK, Kim OJ.

Cytotherapy. 2019 May 7. pii: S1465-3249(19)30458-X. doi: 10.1016/j.jcyt.2019.04.054. [Epub ahead of print]

PMID:
31076196
2.

A 90-Day Repeated Oral Dose Toxicity Study of Alismatis Rhizoma Aqueous Extract in Rats.

Lee MJ, Jung HK, Lee KH, Jang JH, Sim MO, Seong TG, Ahn BK, Shon JH, Ham SH, Cho HW, Kim YM, Park SJ, Yoon JY, Ko JW, Kim JC.

Toxicol Res. 2019 Apr;35(2):191-200. doi: 10.5487/TR.2019.35.2.191. Epub 2019 Apr 15.

3.

Plasma sphingomyelins increase in pre-diabetic Korean men with abdominal obesity.

Im SS, Park HY, Shon JC, Chung IS, Cho HC, Liu KH, Song DK.

PLoS One. 2019 Mar 5;14(3):e0213285. doi: 10.1371/journal.pone.0213285. eCollection 2019.

4.

Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.

Fogle KJ, Smith AR, Satterfield SL, Gutierrez AC, Hertzler JI, McCardell CS, Shon JH, Barile ZJ, Novak MO, Palladino MJ.

Mol Genet Metab. 2019 Apr;126(4):439-447. doi: 10.1016/j.ymgme.2019.01.008. Epub 2019 Jan 17.

PMID:
30683556
5.

Effect of rifampin on enantioselective disposition and anti-hypertensive effect of benidipine.

Sunwoo YE, Nguyen PTT, Chien CM, Ryu JY, Shon J, Shin JG.

Br J Clin Pharmacol. 2019 Apr;85(4):737-745. doi: 10.1111/bcp.13848. Epub 2019 Jan 30.

PMID:
30589098
6.

Genotype-based enrichment study design for minimizing the sample size in bioequivalence studies using tolterodine and CYP2D6 genotype
.

Oh M, Yeo CW, Kim HS, Shon J, Shin JG.

Int J Clin Pharmacol Ther. 2019 Feb;57(2):110-116. doi: 10.5414/CP203297.

PMID:
30574865
7.

Author Correction: Predicting the clinical impact of human mutation with deep neural networks.

Sundaram L, Gao H, Padigepati SR, McRae JF, Li Y, Kosmicki JA, Fritzilas N, Hakenberg J, Dutta A, Shon J, Xu J, Batzoglou S, Li X, Farh KK.

Nat Genet. 2019 Feb;51(2):364. doi: 10.1038/s41588-018-0329-z.

PMID:
30559491
8.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Oct 18;175(3):889. doi: 10.1016/j.cell.2018.10.019. No abstract available.

9.

The Fat Mass- and Obesity-Associated (FTO) Gene to Obesity: Lessons from Mouse Models.

Chang JY, Park JH, Park SE, Shon J, Park YJ.

Obesity (Silver Spring). 2018 Nov;26(11):1674-1686. doi: 10.1002/oby.22301. Epub 2018 Oct 12. Review.

PMID:
30311736
10.

Predicting the clinical impact of human mutation with deep neural networks.

Sundaram L, Gao H, Padigepati SR, McRae JF, Li Y, Kosmicki JA, Fritzilas N, Hakenberg J, Dutta A, Shon J, Xu J, Batzoglou S, Li X, Farh KK.

Nat Genet. 2018 Aug;50(8):1161-1170. doi: 10.1038/s41588-018-0167-z. Epub 2018 Jul 23. Erratum in: Nat Genet. 2019 Feb;51(2):364.

11.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, Cieslik MP, Parolia A, Beer TM, Thomas G, Chi KN, Gleave M, Lack NA, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Ryan CJ, Fong L, Kim W, Friedlander T, Chou J, Li H, Das R, Li H, Moussavi-Baygi R, Goodarzi H, Gilbert LA, Lara PN Jr, Evans CP, Goldstein TC, Stuart JM, Tomlins SA, Spratt DE, Cheetham RK, Cheng DT, Farh K, Gehring JS, Hakenberg J, Liao A, Febbo PG, Shon J, Sickler B, Batzoglou S, Knudsen KE, He HH, Huang J, Wyatt AW, Dehm SM, Ashworth A, Chinnaiyan AM, Maher CA, Small EJ, Feng FY.

Cell. 2018 Jul 26;174(3):758-769.e9. doi: 10.1016/j.cell.2018.06.039. Epub 2018 Jul 19. Erratum in: Cell. 2018 Oct 18;175(3):889.

12.
13.

The combination of mannitol and temozolomide increases the effectiveness of stem cell treatment in a chronic stroke model.

Choi C, Kim HM, Shon J, Park J, Kim HT, Kang SH, Oh SH, Kim NK, Kim OJ.

Cytotherapy. 2018 Jun;20(6):820-829. doi: 10.1016/j.jcyt.2018.04.004.

PMID:
29776835
14.

Terfenadone is a strong inhibitor of CYP2J2 present in the human liver and intestinal microsomes.

Lee E, Kim JH, Shon JC, Wu Z, Kim HJ, Gim M, Lee T, Liu KH.

Drug Metab Pharmacokinet. 2018 Jun;33(3):159-163. doi: 10.1016/j.dmpk.2018.02.001. Epub 2018 Mar 15.

PMID:
29759885
15.

The inhibitory potential of Broussochalcone A for the human cytochrome P450 2J2 isoform and its anti-cancer effects via FOXO3 activation.

Park SH, Lee J, Shon JC, Phuc NM, Jee JG, Liu KH.

Phytomedicine. 2018 Mar 15;42:199-206. doi: 10.1016/j.phymed.2018.03.032. Epub 2018 Mar 19.

PMID:
29655687
16.

Additional increased effects of mannitol-temozolomide combined treatment on blood-brain barrier permeability.

Choi C, Kim HM, Shon J, Park J, Kim HT, Oh SH, Kim NK, Kim OJ.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):769-775. doi: 10.1016/j.bbrc.2018.02.149. Epub 2018 Feb 17.

PMID:
29462622
17.

Cooperative interactions between seed-borne bacterial and air-borne fungal pathogens on rice.

Jung B, Park J, Kim N, Li T, Kim S, Bartley LE, Kim J, Kim I, Kang Y, Yun K, Choi Y, Lee HH, Ji S, Lee KS, Kim BY, Shon JC, Kim WC, Liu KH, Yoon D, Kim S, Seo YS, Lee J.

Nat Commun. 2018 Jan 2;9(1):31. doi: 10.1038/s41467-017-02430-2.

18.

Potent Bis-Cyclometalated Iridium Photoreductants with β-Diketiminate Ancillary Ligands.

Shon JH, Teets TS.

Inorg Chem. 2017 Dec 18;56(24):15295-15303. doi: 10.1021/acs.inorgchem.7b02859. Epub 2017 Nov 27.

PMID:
29172506
19.

The green tea modulates large intestinal microbiome and exo/endogenous metabolome altered through chronic UVB-exposure.

Jung ES, Park HM, Hyun SM, Shon JC, Singh D, Liu KH, Whon TW, Bae JW, Hwang JS, Lee CH.

PLoS One. 2017 Nov 8;12(11):e0187154. doi: 10.1371/journal.pone.0187154. eCollection 2017.

20.

Role of CYP3A in Oral Contraceptives Clearance.

Zhang N, Shon J, Kim MJ, Yu C, Zhang L, Huang SM, Lee L, Tran D, Li L.

Clin Transl Sci. 2018 May;11(3):251-260. doi: 10.1111/cts.12499. Epub 2017 Oct 6. Review. No abstract available.

21.

Acetylshikonin is a novel non-selective cytochrome P450 inhibitor.

Shon JC, Phuc NM, Kim WC, Heo JK, Wu Z, Lee H, Liu KH.

Biopharm Drug Dispos. 2017 Dec;38(9):553-556. doi: 10.1002/bdd.2101. Epub 2017 Nov 6.

PMID:
28866862
22.

Sulfatides Primarily Exist in the Substantia Nigra Region of Mouse Brain Tissue.

Park KT, Shon JC, Kim JE, Park GH, Choi HJ, Liu KH.

Lipids. 2017 Feb;52(2):179-187. doi: 10.1007/s11745-016-4224-z. Epub 2017 Jan 11.

PMID:
28078602
23.

The ATP-sensitive K channel is seizure protective and required for effective dietary therapy in a model of mitochondrial encephalomyopathy.

Fogle KJ, Hertzler JI, Shon JH, Palladino MJ.

J Neurogenet. 2016 Sep - Dec;30(3-4):247-258. Epub 2016 Nov 21.

24.
25.

Bone marrow aspirate concentrate for the treatment of osteochondral lesions of the talus: a systematic review of outcomes.

Chahla J, Cinque ME, Shon JM, Liechti DJ, Matheny LM, LaPrade RF, Clanton TO.

J Exp Orthop. 2016 Dec;3(1):33. Epub 2016 Nov 4. Review. Erratum in: J Exp Orthop. 2016 Dec;3(1):38.

26.

Defatted safflower seed extract inhibits adipogenesis in 3T3-L1 preadipocytes and improves lipid profiles in C57BL/6J ob/ob mice fed a high-fat diet.

Hwang EY, Yu MH, Jung YS, Lee SP, Shon JH, Lee SO.

Nutr Res. 2016 Sep;36(9):995-1003. doi: 10.1016/j.nutres.2016.07.004. Epub 2016 Jul 25.

PMID:
27632920
27.

A mixed methods study to examine the influence of the neighborhood social context on adolescent health service utilization.

Mmari K, Marshall B, Hsu T, Shon JW, Eguavoen A.

BMC Health Serv Res. 2016 Aug 24;16(1):433. doi: 10.1186/s12913-016-1597-x.

28.

Job Satisfaction and Expected Turnover Among Federal, State, and Local Public Health Practitioners.

Leider JP, Harper E, Shon JW, Sellers K, Castrucci BC.

Am J Public Health. 2016 Oct;106(10):1782-8. doi: 10.2105/AJPH.2016.303305. Epub 2016 Aug 23.

29.

Fluorocarbon Modified Low-Molecular-Weight Polyethylenimine for siRNA Delivery.

Johnson ME, Shon J, Guan BM, Patterson JP, Oldenhuis NJ, Eldredge AC, Gianneschi NC, Guan Z.

Bioconjug Chem. 2016 Aug 17;27(8):1784-8. doi: 10.1021/acs.bioconjchem.6b00216. Epub 2016 Jul 29.

PMID:
27457882
30.

Structural identification of skin ceramides containing ω-hydroxy acyl chains using mass spectrometry.

Wu Z, Shon JC, Kim JY, Cho Y, Liu KH.

Arch Pharm Res. 2016 Oct;39(10):1426-1432. Epub 2016 Jul 18.

PMID:
27432202
31.

Simultaneous evaluation of substrate-dependent CYP3A inhibition using a CYP3A probe substrates cocktail.

Lee E, Shon JC, Liu KH.

Biopharm Drug Dispos. 2016 Sep;37(6):366-72. doi: 10.1002/bdd.2019.

PMID:
27323294
32.

Teratogenic drugs and their drug interactions with hormonal contraceptives.

Ahn MR, Li L, Shon J, Bashaw ED, Kim MJ.

Clin Pharmacol Ther. 2016 Sep;100(3):217-9. doi: 10.1002/cpt.384. Epub 2016 May 24.

PMID:
27090193
33.

The Effect of Age on the Pharmacokinetics of Udenafil in Healthy Subjects.

Choi HK, Jung JA, Shon J, Bahng MY, Cho DY, Yeo CW, Kim EY, Shin JG.

J Clin Pharmacol. 2016 Nov;56(11):1372-1377. doi: 10.1002/jcph.739.

PMID:
27006150
34.

Discovery of abnormal lithium-storage sites in molybdenum dioxide electrodes.

Shon JK, Lee HS, Park GO, Yoon J, Park E, Park GS, Kong SS, Jin M, Choi JM, Chang H, Doo S, Kim JM, Yoon WS, Pak C, Kim H, Stucky GD.

Nat Commun. 2016 Mar 22;7:11049. doi: 10.1038/ncomms11049.

35.

Lipidomic platform for structural identification of skin ceramides with α-hydroxyacyl chains.

Wu Z, Shon JC, Lee D, Park KT, Park CS, Lee T, Lee HS, Liu KH.

Anal Bioanal Chem. 2016 Mar;408(8):2069-82. doi: 10.1007/s00216-015-9239-4. Epub 2016 Jan 27.

PMID:
26815554
36.

Synthesis of Ordered Mesoporous Manganese Oxides with Various Oxidation States.

Park GO, Shon JK, Kim YH, Kim JM.

J Nanosci Nanotechnol. 2015 Mar;15(3):2441-5.

PMID:
26413684
37.

Near fatal desquamative interstitial pneumonia with bilateral recurrent tension pneumothorax.

Park DW, Kim TH, Shon JW, Yoon HJ, Park SS, Jeon SC, Choi YW, Paik SS, Kim H.

Sarcoidosis Vasc Diffuse Lung Dis. 2015 Jul 22;32(2):167-71.

PMID:
26278697
38.

Danazol Inhibits Cytochrome P450 2J2 Activity in a Substrate-independent Manner.

Lee E, Wu Z, Shon JC, Liu KH.

Drug Metab Dispos. 2015 Aug;43(8):1250-3. doi: 10.1124/dmd.115.064345. Epub 2015 Jun 5.

PMID:
26048912
39.

Direct infusion MS-based lipid profiling reveals the pharmacological effects of compound K-reinforced ginsenosides in high-fat diet induced obese mice.

Shon JC, Shin HS, Seo YK, Yoon YR, Shin H, Liu KH.

J Agric Food Chem. 2015 Mar 25;63(11):2919-29. doi: 10.1021/jf506216p. Epub 2015 Mar 12.

PMID:
25744175
40.

Pomegranate juice does not affect the disposition of simvastatin in healthy subjects.

Park SJ, Yeo CW, Shim EJ, Kim H, Liu KH, Shin JG, Shon JH.

Eur J Drug Metab Pharmacokinet. 2016 Aug;41(4):339-44. doi: 10.1007/s13318-015-0263-8. Epub 2015 Feb 27.

PMID:
25720525
41.

Urine and serum metabolite profiling of rats fed a high-fat diet and the anti-obesity effects of caffeine consumption.

Kim HY, Lee MY, Park HM, Park YK, Shon JC, Liu KH, Lee CH.

Molecules. 2015 Feb 13;20(2):3107-28. doi: 10.3390/molecules20023107.

42.

Pharmacokinetic study of metformin to compare voglibose/metformin fixed-dose combination with coadministered voglibose and metformin.

Choi HK, Oh M, Kim EJ, Song GS, Ghim JL, Shon JH, Kim HS, Shin JG.

Int J Clin Pharmacol Ther. 2015 Feb;53(2):147-53. doi: 10.5414/CP202197.

43.

Screening of non-steroidal anti-inflammatory drugs for inhibitory effects on the activities of six UDP-glucuronosyltransferases (UGT1A1, 1A3, 1A4, 1A6, 1A9 and 2B7) using LC-MS/MS.

Joo J, Kim YW, Wu Z, Shin JH, Lee B, Shon JC, Lee EY, Phuc NM, Liu KH.

Biopharm Drug Dispos. 2015 May;36(4):258-64. doi: 10.1002/bdd.1933. Epub 2015 Jan 27.

PMID:
25522350
44.

In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.

Joo J, Wu Z, Lee B, Shon JC, Lee T, Lee IK, Sim T, Kim KH, Kim ND, Kim SH, Liu KH.

Biopharm Drug Dispos. 2015 Apr;36(3):163-73. doi: 10.1002/bdd.1929. Epub 2015 Jan 24.

PMID:
25451157
45.

Application of systems pharmacology to explore mechanisms of hepatotoxicity.

Shon J, Abernethy DR.

Clin Pharmacol Ther. 2014 Nov;96(5):536-7. doi: 10.1038/clpt.2014.167.

PMID:
25336266
46.

Mass spectrometry-based metabolite profiling in the mouse liver following exposure to ultraviolet B radiation.

Park HM, Shon JC, Lee MY, Liu KH, Kim JK, Lee SJ, Lee CH.

PLoS One. 2014 Oct 2;9(10):e109479. doi: 10.1371/journal.pone.0109479. eCollection 2014.

47.

Effect of voglibose on the pharmacokinetics of metformin in healthy Korean subjects.

Kim HS, Oh M, Kim EJ, Song GS, Ghim JL, Shon JH, Kim DH, Shin JG.

Int J Clin Pharmacol Ther. 2014 Nov;52(11):1005-11. doi: 10.5414/CP202160.

PMID:
25161160
48.

Fabrication of full-color InGaN-based light-emitting diodes on amorphous substrates by pulsed sputtering.

Shon JW, Ohta J, Ueno K, Kobayashi A, Fujioka H.

Sci Rep. 2014 Jun 23;4:5325. doi: 10.1038/srep05325.

49.

Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease.

Hoa NT, Ge L, Tajhya RB, Beeton C, Cornforth AN, Abolhoda A, Lambrecht N, DaCosta-Iyer M, Ouyang Y, Mai AP, Hong E, Shon J, Hickey MJ, Erickson KL, Kruse CA, Jadus MR.

Am J Transl Res. 2014 May 15;6(3):188-205. eCollection 2014.

50.

Translational informatics in personalized medicine: an update for 2014.

Perakslis ED, Shon J.

Per Med. 2014 May;11(3):339-349. doi: 10.2217/pme.14.8.

PMID:
29764066

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