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Items: 1 to 50 of 197

1.

Injectable hydrogel enables local and sustained co-delivery to the brain: Two clinically approved biomolecules, cyclosporine and erythropoietin, accelerate functional recovery in rat model of stroke.

Tuladhar A, Obermeyer JM, Payne SL, Siu RCW, Zand S, Morshead CM, Shoichet MS.

Biomaterials. 2020 Mar;235:119794. doi: 10.1016/j.biomaterials.2020.119794. Epub 2020 Jan 16.

PMID:
31981761
2.

Induction of Rod and Cone Photoreceptor-Specific Progenitors from Stem Cells.

Ballios BG, Khalili S, Shoichet MS, van der Kooy D.

Adv Exp Med Biol. 2019;1185:551-555. doi: 10.1007/978-3-030-27378-1_90. Review.

PMID:
31884669
3.

Benchmarking to the Gold Standard: Hyaluronan-Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture.

Baker AEG, Bahlmann LC, Tam RY, Liu JC, Ganesh AN, Mitrousis N, Marcellus R, Spears M, Bartlett JMS, Cescon DW, Bader GD, Shoichet MS.

Adv Mater. 2019 Sep;31(36):e1901166. doi: 10.1002/adma.201901166. Epub 2019 Jul 19.

PMID:
31322299
4.

Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates.

Donders EN, Ganesh AN, Torosyan H, Lak P, Shoichet BK, Shoichet MS.

ACS Chem Biol. 2019 Jul 19;14(7):1507-1514. doi: 10.1021/acschembio.9b00247. Epub 2019 Jun 25.

PMID:
31243955
5.

Local delivery of FK506 to injured peripheral nerve enhances axon regeneration after surgical nerve repair in rats.

Tajdaran K, Chan K, Shoichet MS, Gordon T, Borschel GH.

Acta Biomater. 2019 Sep 15;96:211-221. doi: 10.1016/j.actbio.2019.05.058. Epub 2019 May 26.

PMID:
31141732
6.

Effect of Sugar 2',4'-Modifications on Gene Silencing Activity of siRNA Duplexes.

Malek-Adamian E, Fakhoury J, Arnold AE, Martínez-Montero S, Shoichet MS, Damha MJ.

Nucleic Acid Ther. 2019 Aug;29(4):187-194. doi: 10.1089/nat.2019.0792. Epub 2019 May 14.

7.

Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells.

Czupiel PP, Delplace V, Shoichet MS.

J Control Release. 2019 Jul 10;305:210-219. doi: 10.1016/j.jconrel.2019.04.045. Epub 2019 May 6.

PMID:
31071370
8.

A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system.

Ho MT, Teal CJ, Shoichet MS.

Brain Res Bull. 2019 May;148:46-54. doi: 10.1016/j.brainresbull.2019.03.005. Epub 2019 Mar 18. Review.

PMID:
30898580
9.

Modulated Protein Delivery to Engineer Tissue Repair.

Hettiaratchi MH, Shoichet MS.

Tissue Eng Part A. 2019 Jul;25(13-14):925-930. doi: 10.1089/ten.TEA.2019.0066. Epub 2019 Jun 14. Review.

PMID:
30848169
10.

Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence.

Ganesh AN, Aman A, Logie J, Barthel BL, Cogan P, Al-Awar R, Koch TH, Shoichet BK, Shoichet MS.

ACS Chem Biol. 2019 Apr 19;14(4):751-757. doi: 10.1021/acschembio.9b00032. Epub 2019 Mar 12.

11.

Transplantation of Directly Reprogrammed Human Neural Precursor Cells Following Stroke Promotes Synaptogenesis and Functional Recovery.

Vonderwalde I, Azimi A, Rolvink G, Ahlfors JE, Shoichet MS, Morshead CM.

Transl Stroke Res. 2020 Feb;11(1):93-107. doi: 10.1007/s12975-019-0691-x.

12.

Modeling of Photoreceptor Donor-Host Interaction Following Transplantation Reveals a Role for Crx, Müller Glia, and Rho/ROCK Signaling in Neurite Outgrowth.

Tsai ELS, Ortin-Martinez A, Gurdita A, Comanita L, Yan N, Smiley S, Delplace V, Shoichet MS, Nickerson PEB, Wallace VA.

Stem Cells. 2019 Apr;37(4):529-541. doi: 10.1002/stem.2985. Epub 2019 Feb 14.

PMID:
30715780
13.

Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.

Bellver-Landete V, Bretheau F, Mailhot B, Vallières N, Lessard M, Janelle ME, Vernoux N, Tremblay MÈ, Fuehrmann T, Shoichet MS, Lacroix S.

Nat Commun. 2019 Jan 31;10(1):518. doi: 10.1038/s41467-019-08446-0.

14.

Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains.

Hettiaratchi MH, O'Meara MJ, Teal CJ, Payne SL, Pickering AJ, Shoichet MS.

J Control Release. 2019 Mar 10;297:14-25. doi: 10.1016/j.jconrel.2019.01.033. Epub 2019 Jan 25.

PMID:
30690102
15.

Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats.

Obermeyer JM, Tuladhar A, Payne SL, Ho E, Morshead CM, Shoichet MS.

Tissue Eng Part A. 2019 Aug;25(15-16):1175-1187. doi: 10.1089/ten.TEA.2018.0215. Epub 2019 Feb 27.

PMID:
30612516
16.

Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High-Content Drug Screening.

Tam RY, Yockell-Lelièvre J, Smith LJ, Julian LM, Baker AEG, Choey C, Hasim MS, Dimitroulakos J, Stanford WL, Shoichet MS.

Adv Mater. 2019 Feb;31(7):e1806214. doi: 10.1002/adma.201806214. Epub 2018 Dec 27.

PMID:
30589121
17.

Influencing neuroplasticity in stroke treatment with advanced biomaterials-based approaches.

Obermeyer JM, Ho E, Gracias A, Shoichet MS.

Adv Drug Deliv Rev. 2019 Aug;148:204-218. doi: 10.1016/j.addr.2018.12.012. Epub 2018 Dec 21. Review.

PMID:
30579882
18.

Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury.

Nori S, Khazaei M, Ahuja CS, Yokota K, Ahlfors JE, Liu Y, Wang J, Shibata S, Chio J, Hettiaratchi MH, Führmann T, Shoichet MS, Fehlings MG.

Stem Cell Reports. 2018 Dec 11;11(6):1433-1448. doi: 10.1016/j.stemcr.2018.10.017. Epub 2018 Nov 21.

19.

Initial cell maturity changes following transplantation in a hyaluronan-based hydrogel and impacts therapeutic success in the stroke-injured rodent brain.

Payne SL, Tuladhar A, Obermeyer JM, Varga BV, Teal CJ, Morshead CM, Nagy A, Shoichet MS.

Biomaterials. 2019 Feb;192:309-322. doi: 10.1016/j.biomaterials.2018.11.020. Epub 2018 Nov 15.

PMID:
30468998
20.

Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells.

Khalili S, Ballios BG, Belair-Hickey J, Donaldson L, Liu J, Coles BLK, Grisé KN, Baakdhah T, Bader GD, Wallace VA, Bernier G, Shoichet MS, van der Kooy D.

Stem Cell Res. 2018 Dec;33:215-227. doi: 10.1016/j.scr.2018.11.005. Epub 2018 Nov 13.

21.

Controlled release strategy designed for intravitreal protein delivery to the retina.

Delplace V, Ortin-Martinez A, Tsai ELS, Amin AN, Wallace V, Shoichet MS.

J Control Release. 2019 Jan 10;293:10-20. doi: 10.1016/j.jconrel.2018.11.012. Epub 2018 Nov 10.

PMID:
30419267
22.

Colloidal aggregation: from screening nuisance to formulation nuance.

Ganesh AN, Donders EN, Shoichet BK, Shoichet MS.

Nano Today. 2018 Apr;19:188-200. doi: 10.1016/j.nantod.2018.02.011. Epub 2018 Mar 10.

23.

Biomaterials driving repair after stroke.

Tuladhar A, Shoichet MS.

Nat Mater. 2018 Jul;17(7):573-574. doi: 10.1038/s41563-018-0124-3. No abstract available.

PMID:
29941949
24.

The role of biomaterials in overcoming barriers to regeneration in the central nervous system.

Führmann T, Shoichet MS.

Biomed Mater. 2018 Jun 4;13(5):050201. doi: 10.1088/1748-605X/aac2f6. No abstract available.

PMID:
29864020
25.

Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells.

Arnold AE, Malek-Adamian E, Le PU, Meng A, Martínez-Montero S, Petrecca K, Damha MJ, Shoichet MS.

Mol Ther Nucleic Acids. 2018 Jun 1;11:518-527. doi: 10.1016/j.omtn.2018.04.004. Epub 2018 Apr 19.

26.

Muscle stem cell intramuscular delivery within hyaluronan methylcellulose improves engraftment efficiency and dispersion.

Davoudi S, Chin CY, Cooke MJ, Tam RY, Shoichet MS, Gilbert PM.

Biomaterials. 2018 Aug;173:34-46. doi: 10.1016/j.biomaterials.2018.04.048. Epub 2018 Apr 26.

PMID:
29738956
27.

Reply to Comment on 'Adult skin-derived precursor Schwann cell grafts form growths in the injured spinal cord of Fischer rats'.

May Z, Fuehrmann T, Shoichet MS, Tetzlaff W, Biernaskie J, Fouad K.

Biomed Mater. 2018 Apr 11;13(4):048002. doi: 10.1088/1748-605X/aab629. No abstract available.

PMID:
29532786
28.

Photo-immobilized EGF chemical gradients differentially impact breast cancer cell invasion and drug response in defined 3D hydrogels.

Fisher SA, Tam RY, Fokina A, Mahmoodi MM, Distefano MD, Shoichet MS.

Biomaterials. 2018 Sep;178:751-766. doi: 10.1016/j.biomaterials.2018.01.032. Epub 2018 Feb 13.

29.

Diels-Alder Click-Cross-Linked Hydrogels with Increased Reactivity Enable 3D Cell Encapsulation.

Smith LJ, Taimoory SM, Tam RY, Baker AEG, Binth Mohammad N, Trant JF, Shoichet MS.

Biomacromolecules. 2018 Mar 12;19(3):926-935. doi: 10.1021/acs.biomac.7b01715. Epub 2018 Feb 23.

PMID:
29443512
30.

Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury.

Führmann T, Anandakumaran PN, Payne SL, Pakulska MM, Varga BV, Nagy A, Tator C, Shoichet MS.

Biomed Mater. 2018 Feb 2;13(2):024103. doi: 10.1088/1748-605X/aa96dc.

PMID:
29083317
31.

Adult skin-derived precursor Schwann cell grafts form growths in the injured spinal cord of Fischer rats.

May Z, Kumar R, Fuehrmann T, Tam R, Vulic K, Forero J, Lucas Osma A, Fenrich K, Assinck P, Lee MJ, Moulson A, Shoichet MS, Tetzlaff W, Biernaskie J, Fouad K.

Biomed Mater. 2018 Feb 20;13(3):034101. doi: 10.1088/1748-605X/aa95f8.

PMID:
29068322
32.

Independently Tuning the Biochemical and Mechanical Properties of 3D Hyaluronan-Based Hydrogels with Oxime and Diels-Alder Chemistry to Culture Breast Cancer Spheroids.

Baker AEG, Tam RY, Shoichet MS.

Biomacromolecules. 2017 Dec 11;18(12):4373-4384. doi: 10.1021/acs.biomac.7b01422. Epub 2017 Oct 31.

PMID:
29040808
33.

Human Pluripotent Stem Cell-Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis.

Julian LM, Delaney SP, Wang Y, Goldberg AA, Doré C, Yockell-Lelièvre J, Tam RY, Giannikou K, McMurray F, Shoichet MS, Harper ME, Henske EP, Kwiatkowski DJ, Darling TN, Moss J, Kristof AS, Stanford WL.

Cancer Res. 2017 Oct 15;77(20):5491-5502. doi: 10.1158/0008-5472.CAN-17-0925. Epub 2017 Aug 22.

34.

In Vitro Maturation of Human iPSC-Derived Neuroepithelial Cells Influences Transplant Survival in the Stroke-Injured Rat Brain.

Payne SL, Anandakumaran PN, Varga BV, Morshead CM, Nagy A, Shoichet MS.

Tissue Eng Part A. 2018 Feb;24(3-4):351-360. doi: 10.1089/ten.TEA.2016.0515. Epub 2017 Jul 11.

PMID:
28594288
35.

Leveraging Colloidal Aggregation for Drug-Rich Nanoparticle Formulations.

Ganesh AN, Logie J, McLaughlin CK, Barthel BL, Koch TH, Shoichet BK, Shoichet MS.

Mol Pharm. 2017 Jun 5;14(6):1852-1860. doi: 10.1021/acs.molpharmaceut.6b01015. Epub 2017 May 19.

36.

Designing Peptide and Protein Modified Hydrogels: Selecting the Optimal Conjugation Strategy.

Fisher SA, Baker AEG, Shoichet MS.

J Am Chem Soc. 2017 Jun 7;139(22):7416-7427. doi: 10.1021/jacs.7b00513. Epub 2017 May 23.

PMID:
28481537
37.

Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord.

Pakulska MM, Tator CH, Shoichet MS.

Biomaterials. 2017 Jul;134:13-21. doi: 10.1016/j.biomaterials.2017.04.016. Epub 2017 Apr 18.

PMID:
28453954
38.

Engineering Cellular Microenvironments with Photo- and Enzymatically Responsive Hydrogels: Toward Biomimetic 3D Cell Culture Models.

Tam RY, Smith LJ, Shoichet MS.

Acc Chem Res. 2017 Apr 18;50(4):703-713. doi: 10.1021/acs.accounts.6b00543. Epub 2017 Mar 27.

PMID:
28345876
39.

A New Spin on Antibody-Drug Conjugates: Trastuzumab-Fulvestrant Colloidal Drug Aggregates Target HER2-Positive Cells.

Ganesh AN, McLaughlin CK, Duan D, Shoichet BK, Shoichet MS.

ACS Appl Mater Interfaces. 2017 Apr 12;9(14):12195-12202. doi: 10.1021/acsami.6b15987. Epub 2017 Mar 28.

40.

Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help?

Führmann T, Anandakumaran PN, Shoichet MS.

Adv Healthc Mater. 2017 May;6(10). doi: 10.1002/adhm.201601130. Epub 2017 Mar 1. Review.

PMID:
28247563
41.

Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model.

Logie J, Ganesh AN, Aman AM, Al-Awar RS, Shoichet MS.

Biomaterials. 2017 Apr;123:39-47. doi: 10.1016/j.biomaterials.2017.01.026. Epub 2017 Jan 26.

PMID:
28161682
42.

Internal Structure and Preferential Protein Binding of Colloidal Aggregates.

Duan D, Torosyan H, Elnatan D, McLaughlin CK, Logie J, Shoichet MS, Agard DA, Shoichet BK.

ACS Chem Biol. 2017 Jan 20;12(1):282-290. doi: 10.1021/acschembio.6b00791. Epub 2016 Dec 16.

43.

6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning.

Mahmoodi MM, Fisher SA, Tam RY, Goff PC, Anderson RB, Wissinger JE, Blank DA, Shoichet MS, Distefano MD.

Org Biomol Chem. 2016 Sep 21;14(35):8289-300. doi: 10.1039/c6ob01045h. Epub 2016 Aug 16.

44.

Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model.

Gomes ED, Mendes SS, Leite-Almeida H, Gimble JM, Tam RY, Shoichet MS, Sousa N, Silva NA, Salgado AJ.

Biomaterials. 2016 Oct;105:38-51. doi: 10.1016/j.biomaterials.2016.07.019. Epub 2016 Jul 20.

PMID:
27505621
45.

Local Affinity Release.

Delplace V, Obermeyer J, Shoichet MS.

ACS Nano. 2016 Jul 26;10(7):6433-6. doi: 10.1021/acsnano.6b04308. Epub 2016 Jul 12.

PMID:
27403513
46.

Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles.

Pakulska MM, Elliott Donaghue I, Obermeyer JM, Tuladhar A, McLaughlin CK, Shendruk TN, Shoichet MS.

Sci Adv. 2016 May 27;2(5):e1600519. doi: 10.1126/sciadv.1600519. eCollection 2016 May.

47.

Local Delivery of Neurotrophin-3 and Anti-NogoA Promotes Repair After Spinal Cord Injury.

Elliott Donaghue I, Tator CH, Shoichet MS.

Tissue Eng Part A. 2016 May;22(9-10):733-41. doi: 10.1089/ten.TEA.2015.0471. Epub 2016 May 5.

PMID:
27056081
48.

Designer protein delivery: From natural to engineered affinity-controlled release systems.

Pakulska MM, Miersch S, Shoichet MS.

Science. 2016 Mar 18;351(6279):aac4750. doi: 10.1126/science.aac4750. Review.

PMID:
26989257
49.

Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model.

Führmann T, Tam RY, Ballarin B, Coles B, Elliott Donaghue I, van der Kooy D, Nagy A, Tator CH, Morshead CM, Shoichet MS.

Biomaterials. 2016 Mar;83:23-36. doi: 10.1016/j.biomaterials.2015.12.032. Epub 2016 Jan 1.

PMID:
26773663
50.

Hydrogel for Simultaneous Tunable Growth Factor Delivery and Enhanced Viability of Encapsulated Cells in Vitro.

Parker J, Mitrousis N, Shoichet MS.

Biomacromolecules. 2016 Feb 8;17(2):476-84. doi: 10.1021/acs.biomac.5b01366. Epub 2016 Jan 25.

PMID:
26762290

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