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Items: 1 to 20 of 159

1.

Serine hydroxymethyltransferase 1 promoter hypermethylation increases the risk of essential hypertension.

Xu G, Wang C, Ying X, Kong F, Ji H, Zhao J, Zhang X, Duan S, Han L, Li L.

J Clin Lab Anal. 2018 Nov 9:e22712. doi: 10.1002/jcla.22712. [Epub ahead of print]

PMID:
30411815
2.

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG.

Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4.

3.

Aberrant expression of hsa_circ_0025036 in lung adenocarcinoma and its potential roles in regulating cell proliferation and apoptosis.

Wu S, Li H, Lu C, Zhang F, Wang H, Lu X, Zhang G.

Biol Chem. 2018 Nov 27;399(12):1457-1467. doi: 10.1515/hsz-2018-0303.

PMID:
30138108
4.

Role of Cytosolic Serine Hydroxymethyl Transferase 1 (SHMT1) in Phosphate-Induced Vascular Smooth Muscle Cell Calcification.

Boehme B, Schelski N, Makridakis M, Henze L, Vlahou A, Lang F, Pieske B, Alesutan I, Voelkl J.

Kidney Blood Press Res. 2018;43(4):1212-1221. doi: 10.1159/000492248. Epub 2018 Aug 2.

5.

The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.

Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico MC, Bouzidi A, Pontecorvi V, Guiducci G, Zamparelli C, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F.

FEBS J. 2018 Sep;285(17):3238-3253. doi: 10.1111/febs.14610. Epub 2018 Aug 7.

PMID:
30035852
6.

Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.

Tramonti A, Paiardini A, Paone A, Bouzidi A, Giardina G, Guiducci G, Magnifico MC, Rinaldo S, McDermott L, Menendez JA, Contestabile R, Cutruzzolà F.

Arch Biochem Biophys. 2018 Sep 1;653:71-79. doi: 10.1016/j.abb.2018.07.001. Epub 2018 Jul 4.

PMID:
29991441
7.

Dietary Uridine Decreases Tumorigenesis in the ApcMin/+ Model of Intestinal Cancer.

Field MS, Lan X, Stover DM, Stover PJ.

Curr Dev Nutr. 2018 Mar 13;2(5):nzy013. doi: 10.1093/cdn/nzy013. eCollection 2018 May.

8.

Identification of three novel loci of ALDH2 Gene for Serum Folate levels in a Male Chinese Population by Genome-Wide Association Study.

Deng C, Tang S, Huang X, Gao J, Tian J, Zhou X, Xie Y, Liao M, Mo Z, Wang Q.

Gene. 2018 Oct 20;674:121-126. doi: 10.1016/j.gene.2018.06.080. Epub 2018 Jun 25.

PMID:
29953918
9.

SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.

Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA.

PLoS Pathog. 2018 May 23;14(5):e1007071. doi: 10.1371/journal.ppat.1007071. eCollection 2018 May.

10.

Metal induction of two metallothionein genes in the ectomycorrhizal fungus Suillus himalayensis and their role in metal tolerance.

Kalsotra T, Khullar S, Agnihotri R, Reddy MS.

Microbiology. 2018 Jun;164(6):868-876. doi: 10.1099/mic.0.000666. Epub 2018 May 15.

PMID:
29762106
11.

Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold.

Schwertz G, Witschel MC, Rottmann M, Leartsakulpanich U, Chitnumsub P, Jaruwat A, Amornwatcharapong W, Ittarat W, Schäfer A, Aponte RA, Trapp N, Chaiyen P, Diederich F.

ChemMedChem. 2018 May 8;13(9):931-943. doi: 10.1002/cmdc.201800053. Epub 2018 Apr 14.

PMID:
29655285
12.

The association between donor genetic variations in one-carbon metabolism pathway genes and hepatitis B recurrence after liver transplantation.

Lu D, Zhuo J, Yang M, Wang C, Pan L, Xie H, Xu X, Zheng S.

Gene. 2018 Jul 15;663:121-125. doi: 10.1016/j.gene.2018.03.071. Epub 2018 Apr 5.

PMID:
29627528
13.

The role of the folate pathway in pancreatic cancer risk.

Chittiboyina S, Chen Z, Chiorean EG, Kamendulis LM, Hocevar BA.

PLoS One. 2018 Feb 23;13(2):e0193298. doi: 10.1371/journal.pone.0193298. eCollection 2018.

14.

Neuro-fuzzy model of homocysteine metabolism.

Naushad SM, Rama Devi AR, Nivetha S, Lakshmitha G, Stanley AB, Hussain T, Kutala VK.

J Genet. 2017 Dec;96(6):919-926.

15.

Frequency of folate-related polymorphisms varies by skin pigmentation.

Jones P, Lucock M, Veysey M, Jablonski N, Chaplin G, Beckett E.

Am J Hum Biol. 2018 Mar;30(2). doi: 10.1002/ajhb.23079. Epub 2017 Nov 21.

PMID:
29159983
16.

Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.

Ducker GS, Ghergurovich JM, Mainolfi N, Suri V, Jeong SK, Hsin-Jung Li S, Friedman A, Manfredi MG, Gitai Z, Kim H, Rabinowitz JD.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409. doi: 10.1073/pnas.1706617114. Epub 2017 Oct 9.

17.

One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.

Moruzzi S, Guarini P, Udali S, Ruzzenente A, Guglielmi A, Conci S, Pattini P, Martinelli N, Olivieri O, Tammen SA, Choi SW, Friso S.

PLoS One. 2017 Oct 2;12(10):e0185792. doi: 10.1371/journal.pone.0185792. eCollection 2017.

18.

Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice.

Speckmann B, Schulz S, Hiller F, Hesse D, Schumacher F, Kleuser B, Geisel J, Obeid R, Grune T, Kipp AP.

J Nutr Biochem. 2017 Oct;48:112-119. doi: 10.1016/j.jnutbio.2017.07.002. Epub 2017 Jul 9.

19.

Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches.

K Rebekah P, Tella S, Buragadda S, Tiruvatturu MK, Akka J.

Birth Defects Res. 2017 Jul 17;109(13):1020-1029. doi: 10.1002/bdr2.23623.

PMID:
28762673
20.

Duplication 17p11.2 (Potocki-Lupski Syndrome) in a child with developmental delay.

Shuib S, Saaid NN, Zakaria Z, Ismail J, Abdul Latiff Z.

Malays J Pathol. 2017 Apr;39(1):77-81.

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