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Items: 29

1.

Evolutionary trajectory of leukemic clones and its clinical implications.

Tuval A, Shlush LI.

Haematologica. 2019 May;104(5):872-880. doi: 10.3324/haematol.2018.195289. Epub 2019 Apr 19. Review.

2.

Identification of a novel PCNT founder pathogenic variant in the Israeli Druze population.

Weiss K, Ekhilevitch N, Cohen L, Bratman-Morag S, Bello R, Martinez AF, Hadid Y, Shlush LI, Kurolap A, Paperna T, Mory A, Baris HN, Muenke M.

Eur J Med Genet. 2019 Mar 25. pii: S1769-7212(18)30595-0. doi: 10.1016/j.ejmg.2019.03.007. [Epub ahead of print]

PMID:
30922925
3.

Connections Between Clonal Hematopoiesis, Cardiovascular Disease, and Cancer: A Review.

Calvillo-Argüelles O, Jaiswal S, Shlush LI, Moslehi JJ, Schimmer A, Barac A, Thavendiranathan P.

JAMA Cardiol. 2019 Mar 13. doi: 10.1001/jamacardio.2019.0302. [Epub ahead of print]

PMID:
30865214
4.

Prediction of acute myeloid leukaemia risk in healthy individuals.

Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N, Niemeyer E, Barda N, Zuzarte PC, Heisler L, Sundaravadanam Y, Luben R, Hayat S, Wang TT, Zhao Z, Cirlan I, Pugh TJ, Soave D, Ng K, Latimer C, Hardy C, Raine K, Jones D, Hoult D, Britten A, McPherson JD, Johansson M, Mbabaali F, Eagles J, Miller JK, Pasternack D, Timms L, Krzyzanowski P, Awadalla P, Costa R, Segal E, Bratman SV, Beer P, Behjati S, Martincorena I, Wang JCY, Bowles KM, Quirós JR, Karakatsani A, La Vecchia C, Trichopoulou A, Salamanca-Fernández E, Huerta JM, Barricarte A, Travis RC, Tumino R, Masala G, Boeing H, Panico S, Kaaks R, Krämer A, Sieri S, Riboli E, Vineis P, Foll M, McKay J, Polidoro S, Sala N, Khaw KT, Vermeulen R, Campbell PJ, Papaemmanuil E, Minden MD, Tanay A, Balicer RD, Wareham NJ, Gerstung M, Dick JE, Brennan P, Vassiliou GS, Shlush LI.

Nature. 2018 Jul;559(7714):400-404. doi: 10.1038/s41586-018-0317-6. Epub 2018 Jul 9.

5.

Age-related clonal hematopoiesis.

Shlush LI.

Blood. 2018 Feb 1;131(5):496-504. doi: 10.1182/blood-2017-07-746453. Epub 2017 Nov 15. Review.

6.

Tracing the origins of relapse in acute myeloid leukaemia to stem cells.

Shlush LI, Mitchell A, Heisler L, Abelson S, Ng SWK, Trotman-Grant A, Medeiros JJF, Rao-Bhatia A, Jaciw-Zurakowsky I, Marke R, McLeod JL, Doedens M, Bader G, Voisin V, Xu C, McPherson JD, Hudson TJ, Wang JCY, Minden MD, Dick JE.

Nature. 2017 Jul 6;547(7661):104-108. doi: 10.1038/nature22993. Epub 2017 Jun 28.

PMID:
28658204
7.

Biological and clinical consequences of NPM1 mutations in AML.

Heath EM, Chan SM, Minden MD, Murphy T, Shlush LI, Schimmer AD.

Leukemia. 2017 Apr;31(4):798-807. doi: 10.1038/leu.2017.30. Epub 2017 Jan 23. Review.

PMID:
28111462
8.

Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.

Notta F, Chan-Seng-Yue M, Lemire M, Li Y, Wilson GW, Connor AA, Denroche RE, Liang SB, Brown AM, Kim JC, Wang T, Simpson JT, Beck T, Borgida A, Buchner N, Chadwick D, Hafezi-Bakhtiari S, Dick JE, Heisler L, Hollingsworth MA, Ibrahimov E, Jang GH, Johns J, Jorgensen LG, Law C, Ludkovski O, Lungu I, Ng K, Pasternack D, Petersen GM, Shlush LI, Timms L, Tsao MS, Wilson JM, Yung CK, Zogopoulos G, Bartlett JM, Alexandrov LB, Real FX, Cleary SP, Roehrl MH, McPherson JD, Stein LD, Hudson TJ, Campbell PJ, Gallinger S.

Nature. 2017 Feb 2;542(7639):124. doi: 10.1038/nature20164. Epub 2016 Nov 16. No abstract available.

PMID:
27851734
9.

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.

Notta F, Chan-Seng-Yue M, Lemire M, Li Y, Wilson GW, Connor AA, Denroche RE, Liang SB, Brown AM, Kim JC, Wang T, Simpson JT, Beck T, Borgida A, Buchner N, Chadwick D, Hafezi-Bakhtiari S, Dick JE, Heisler L, Hollingsworth MA, Ibrahimov E, Jang GH, Johns J, Jorgensen LG, Law C, Ludkovski O, Lungu I, Ng K, Pasternack D, Petersen GM, Shlush LI, Timms L, Tsao MS, Wilson JM, Yung CK, Zogopoulos G, Bartlett JM, Alexandrov LB, Real FX, Cleary SP, Roehrl MH, McPherson JD, Stein LD, Hudson TJ, Campbell PJ, Gallinger S.

Nature. 2016 Oct 20;538(7625):378-382. doi: 10.1038/nature19823. Epub 2016 Oct 12. Erratum in: Nature. 2017 Feb 2;542(7639):124.

10.

Change comes like a little wind: tales in MDS evolution.

Shlush LI.

Blood. 2016 Sep 1;128(9):1162-3. doi: 10.1182/blood-2016-07-722660. No abstract available.

11.

AML evolution from preleukemia to leukemia and relapse.

Shlush LI, Mitchell A.

Best Pract Res Clin Haematol. 2015 Jun-Sep;28(2-3):81-9. doi: 10.1016/j.beha.2015.10.004. Epub 2015 Oct 22. Review.

PMID:
26590763
12.

Aging, clonal hematopoiesis and preleukemia: not just bad luck?

Shlush LI, Zandi S, Itzkovitz S, Schuh AC.

Int J Hematol. 2015 Nov;102(5):513-22. doi: 10.1007/s12185-015-1870-5. Epub 2015 Oct 6. Review.

PMID:
26440972
13.

Clonal evolution models of tumor heterogeneity.

Shlush LI, Hershkovitz D.

Am Soc Clin Oncol Educ Book. 2015:e662-5. doi: 10.14694/EdBook_AM.2015.35.e662. Review.

14.

Preleukemia: the normal side of cancer.

Shlush LI, Minden MD.

Curr Opin Hematol. 2015 Mar;22(2):77-84. doi: 10.1097/MOH.0000000000000111. Review.

PMID:
25575035
15.

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.

Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, Kennedy JA, Schimmer AD, Schuh AC, Yee KW, McLeod JL, Doedens M, Medeiros JJ, Marke R, Kim HJ, Lee K, McPherson JD, Hudson TJ; HALT Pan-Leukemia Gene Panel Consortium, Brown AM, Yousif F, Trinh QM, Stein LD, Minden MD, Wang JC, Dick JE.

Nature. 2014 Feb 20;506(7488):328-33. doi: 10.1038/nature13038. Epub 2014 Feb 12. Erratum in: Nature. 2014 Apr 17;508(7496):420. Yousif, Fouad [added].

16.

Single cell analysis exposes intratumor heterogeneity and suggests that FLT3-ITD is a late event in leukemogenesis.

Shouval R, Shlush LI, Yehudai-Resheff S, Ali S, Pery N, Shapiro E, Tzukerman M, Rowe JM, Zuckerman T.

Exp Hematol. 2014 Jun;42(6):457-63. doi: 10.1016/j.exphem.2014.01.010. Epub 2014 Feb 2.

PMID:
24495871
17.

Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations.

Chapal-Ilani N, Maruvka YE, Spiro A, Reizel Y, Adar R, Shlush LI, Shapiro E.

PLoS Comput Biol. 2013;9(11):e1003297. doi: 10.1371/journal.pcbi.1003297. Epub 2013 Nov 14.

18.

Digital image analysis of cells stained with the senescence-associated β-galactosidase assay.

Shlush LI, Selig S.

Methods Mol Biol. 2013;1048:11-8. doi: 10.1007/978-1-62703-556-9_2.

PMID:
23929094
19.

Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability.

Shlush LI, Chapal-Ilani N, Adar R, Pery N, Maruvka Y, Spiro A, Shouval R, Rowe JM, Tzukerman M, Bercovich D, Izraeli S, Marcucci G, Bloomfield CD, Zuckerman T, Skorecki K, Shapiro E.

Blood. 2012 Jul 19;120(3):603-12. doi: 10.1182/blood-2011-10-388629. Epub 2012 May 29.

20.

Colon stem cell and crypt dynamics exposed by cell lineage reconstruction.

Reizel Y, Chapal-Ilani N, Adar R, Itzkovitz S, Elbaz J, Maruvka YE, Segev E, Shlush LI, Dekel N, Shapiro E.

PLoS Genet. 2011 Jul;7(7):e1002192. doi: 10.1371/journal.pgen.1002192. Epub 2011 Jul 28.

21.

Quantitative digital in situ senescence-associated β-galactosidase assay.

Shlush LI, Itzkovitz S, Cohen A, Rutenberg A, Berkovitz R, Yehezkel S, Shahar H, Selig S, Skorecki K.

BMC Cell Biol. 2011 Apr 15;12:16. doi: 10.1186/1471-2121-12-16.

22.

Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress--implications for tissue and organismal aging.

Shlush LI, Skorecki KL, Itzkovitz S, Yehezkel S, Segev Y, Shachar H, Berkovitz R, Adir Y, Vulto I, Lansdorp PM, Selig S.

Mech Ageing Dev. 2011 Mar;132(3):123-30. doi: 10.1016/j.mad.2011.01.005. Epub 2011 Feb 12.

PMID:
21320523
23.

Admixture mapping of end stage kidney disease genetic susceptibility using estimated mutual information ancestry informative markers.

Shlush LI, Bercovici S, Wasser WG, Yudkovsky G, Templeton A, Geiger D, Skorecki K.

BMC Med Genomics. 2010 Oct 18;3:47. doi: 10.1186/1755-8794-3-47.

24.

Population mixture model for nonlinear telomere dynamics.

Itzkovitz S, Shlush LI, Gluck D, Skorecki K.

Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Dec;78(6 Pt 1):060902. Epub 2008 Dec 23.

PMID:
19256795
25.

Ashkenazi Jewish centenarians do not demonstrate enrichment in mitochondrial haplogroup J.

Shlush LI, Atzmon G, Weisshof R, Behar D, Yudkovsky G, Barzilai N, Skorecki K.

PLoS One. 2008;3(10):e3425. doi: 10.1371/journal.pone.0003425. Epub 2008 Oct 16.

26.

The Druze: a population genetic refugium of the Near East.

Shlush LI, Behar DM, Yudkovsky G, Templeton A, Hadid Y, Basis F, Hammer M, Itzkovitz S, Skorecki K.

PLoS One. 2008 May 7;3(5):e2105. doi: 10.1371/journal.pone.0002105.

27.

A homozygous missense mutation in PEPD encoding peptidase D causes prolidase deficiency associated with hyper-IgE syndrome.

Hershkovitz T, Hassoun G, Indelman M, Shlush LI, Bergman R, Pollack S, Sprecher E.

Clin Exp Dermatol. 2006 May;31(3):435-40.

PMID:
16681595
28.

Absence of HIV-associated nephropathy in Ethiopians.

Behar DM, Shlush LI, Maor C, Lorber M, Skorecki K.

Am J Kidney Dis. 2006 Jan;47(1):88-94.

PMID:
16377389
29.

Molecular epidemiological analysis of the changing nature of a meningococcal outbreak following a vaccination campaign.

Shlush LI, Behar DM, Zelazny A, Keller N, Lupski JR, Beaudet AL, Bercovich D.

J Clin Microbiol. 2002 Oct;40(10):3565-71.

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