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Items: 46


Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents.

Luo Z, Shivakumar P, Mourya R, Gutta S, Bezerra JA.

Gastroenterology. 2019 Jun 19. pii: S0016-5085(19)41016-0. doi: 10.1053/j.gastro.2019.06.017. [Epub ahead of print]


Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion.

Peters AL, Luo Z, Li J, Mourya R, Wang Y, Dexheimer P, Shivakumar P, Aronow B, Bezerra JA.

PLoS One. 2019 Apr 25;14(4):e0215481. doi: 10.1371/journal.pone.0215481. eCollection 2019.


Regulation of epithelial injury and bile duct obstruction by NLRP3, IL-1R1 in experimental biliary atresia.

Yang L, Mizuochi T, Shivakumar P, Mourya R, Luo Z, Gutta S, Bezerra JA.

J Hepatol. 2018 Nov;69(5):1136-1144. doi: 10.1016/j.jhep.2018.05.038. Epub 2018 Jun 8.


The elmo-mbc complex and rhogap19d couple Rho family GTPases during mesenchymal-to-epithelial-like transitions.

Toret CP, Shivakumar PC, Lenne PF, Le Bivic A.

Development. 2018 Feb 2. pii: dev.157495. doi: 10.1242/dev.157495. [Epub ahead of print]


Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.

Lertudomphonwanit C, Mourya R, Fei L, Zhang Y, Gutta S, Yang L, Bove KE, Shivakumar P, Bezerra JA.

Sci Transl Med. 2017 Nov 22;9(417). pii: eaan8462. doi: 10.1126/scitranslmed.aan8462.


A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis.

Huang W, Rainbow DB, Wu Y, Adams D, Shivakumar P, Kottyan L, Karns R, Aronow B, Bezerra J, Gershwin ME, Peterson LB, Wicker LS, Ridgway WM.

J Immunol. 2018 Jan 1;200(1):147-162. doi: 10.4049/jimmunol.1701087. Epub 2017 Nov 20.


Hepatic Natural Killer T-cell and CD8+ T-cell Signatures in Mice with Nonalcoholic Steatohepatitis.

Bhattacharjee J, Kirby M, Softic S, Miles L, Salazar-Gonzalez RM, Shivakumar P, Kohli R.

Hepatol Commun. 2017 Jun;1(4):299-310. doi: 10.1002/hep4.1041. Epub 2017 May 16.


Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.

Jee J, Mourya R, Shivakumar P, Fei L, Wagner M, Bezerra JA.

PLoS One. 2017 Aug 1;12(8):e0182089. doi: 10.1371/journal.pone.0182089. eCollection 2017.


Preferential TNFα signaling via TNFR2 regulates epithelial injury and duct obstruction in experimental biliary atresia.

Shivakumar P, Mizuochi T, Mourya R, Gutta S, Yang L, Luo Z, Bezerra JA.

JCI Insight. 2017 Mar 9;2(5):e88747. doi: 10.1172/jci.insight.88747.


Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.

Asai A, Aihara E, Watson C, Mourya R, Mizuochi T, Shivakumar P, Phelan K, Mayhew C, Helmrath M, Takebe T, Wells J, Bezerra JA.

Development. 2017 Mar 15;144(6):1056-1064. doi: 10.1242/dev.142794.


Laser Ablation to Probe the Epithelial Mechanics in Drosophila.

Shivakumar PC, Lenne PF.

Methods Mol Biol. 2016;1478:241-251. Review.


Natural killer cells promote long-term hepatobiliary inflammation in a low-dose rotavirus model of experimental biliary atresia.

Squires JE, Shivakumar P, Mourya R, Bessho K, Walters S, Bezerra JA.

PLoS One. 2015 May 19;10(5):e0127191. doi: 10.1371/journal.pone.0127191. eCollection 2015.


Identifying psychological distress in elderly seeking health care.

Shivakumar P, Sadanand S, Bharath S, Girish N, Philip M, Varghese M.

Indian J Public Health. 2015 Jan-Mar;59(1):18-23. doi: 10.4103/0019-557X.152849.


Gastroprotective Effect of Freeze Dried Stripped Snakehead Fish (Channa striata Bloch.) Aqueous Extract against Aspirin Induced Ulcerogenesis in Pylorus Ligated Rats.

Ali Khan MS, Mat Jais AM, Hussain J, Siddiqua F, Gopala Reddy A, Shivakumar P, Madhuri D.

ISRN Pharmacol. 2014 May 29;2014:327606. doi: 10.1155/2014/327606. eCollection 2014.


Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.

Li J, Razumilava N, Gores GJ, Walters S, Mizuochi T, Mourya R, Bessho K, Wang YH, Glaser SS, Shivakumar P, Bezerra JA.

J Clin Invest. 2014 Jul;124(7):3241-51. doi: 10.1172/JCI73742. Epub 2014 Jun 2.


Fast food diet with CCl4 micro-dose induced hepatic-fibrosis--a novel animal model.

Chheda TK, Shivakumar P, Sadasivan SK, Chanderasekharan H, Moolemath Y, Oommen AM, Madanahalli JR, Marikunte VV.

BMC Gastroenterol. 2014 May 10;14:89. doi: 10.1186/1471-230X-14-89.


Reply: To PMID 24493287.

Mourya R, Bessho K, Shivakumar P, Bezerra JA.

Hepatology. 2015 Feb;61(2):732-3. doi: 10.1002/hep.27231. Epub 2014 Jul 31. No abstract available.


Expansion of prominin-1-expressing cells in association with fibrosis of biliary atresia.

Mavila N, James D, Shivakumar P, Nguyen MV, Utley S, Mak K, Wu A, Zhou S, Wang L, Vendyres C, Groff M, Asahina K, Wang KS.

Hepatology. 2014 Sep;60(3):941-53. doi: 10.1002/hep.27203. Epub 2014 Jul 17.


Gene expression signature for biliary atresia and a role for interleukin-8 in pathogenesis of experimental disease.

Bessho K, Mourya R, Shivakumar P, Walters S, Magee JC, Rao M, Jegga AG, Bezerra JA.

Hepatology. 2014 Jul;60(1):211-23. doi: 10.1002/hep.27045. Epub 2014 May 27.


Identifying elders with neuropsychiatric problems in a clinical setting.

Sadanand S, Shivakumar P, Girish N, Loganathan S, Bagepally BS, Kota LN, Reddy NN, Sivakumar PT, Bharath S, Varghese M.

J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S24-30. doi: 10.4103/0976-3147.116438.


Integrative genomics identifies candidate microRNAs for pathogenesis of experimental biliary atresia.

Bessho K, Shanmukhappa K, Sheridan R, Shivakumar P, Mourya R, Walters S, Kaimal V, Dilbone E, Jegga AG, Bezerra JA.

BMC Syst Biol. 2013 Oct 20;7:104. doi: 10.1186/1752-0509-7-104.


Perforin and granzymes work in synergy to mediate cholangiocyte injury in experimental biliary atresia.

Shivakumar P, Mourya R, Bezerra JA.

J Hepatol. 2014 Feb;60(2):370-6. doi: 10.1016/j.jhep.2013.09.021. Epub 2013 Oct 2.


Evaluation of protective effect of N-acetyl cysteine on arsenic-induced hepatotoxicity.

Hemalatha P, Reddy AG, Reddy YR, Shivakumar P.

J Nat Sci Biol Med. 2013 Jul;4(2):393-5. doi: 10.4103/0976-9668.116986.


Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice.

DiPaola F, Shivakumar P, Pfister J, Walters S, Sabla G, Bezerra JA.

Hepatology. 2013 Oct;58(4):1486-1496. doi: 10.1002/hep.26485. Epub 2013 Aug 6.


A study on the toxic effects of Doxorubicin on the histology of certain organs.

Shivakumar P, Rani MU, Reddy AG, Anjaneyulu Y.

Toxicol Int. 2012 Sep;19(3):241-4. doi: 10.4103/0971-6580.103656.


Dementia and diabetes mellitus: association with apolipoprotein e4 polymorphism from a hospital in southern India.

Kota LN, Shankarappa BM, Shivakumar P, Sadanand S, Bagepally BS, Krishnappa SB, Purushottam M, Sivakumar PT, Jain S, Varghese M, Bharath S.

Int J Alzheimers Dis. 2012;2012:702972. doi: 10.1155/2012/702972. Epub 2012 Jun 3.


Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype.

Li J, Bessho K, Shivakumar P, Mourya R, Mohanty SK, Dos Santos JL, Miura IK, Porta G, Bezerra JA.

J Clin Invest. 2011 Nov;121(11):4244-56. doi: 10.1172/JCI57728. Epub 2011 Oct 17.


Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia.

Saxena V, Shivakumar P, Sabla G, Mourya R, Chougnet C, Bezerra JA.

Sci Transl Med. 2011 Sep 28;3(102):102ra94. doi: 10.1126/scitranslmed.3002069.


Idiopathic granulomatous appendicitis: a rare appendicular pseudo tumor.

Shivakumar P, Shanmugam RP, Mani CS.

Trop Gastroenterol. 2010 Apr-Jun;31(2):130-1. No abstract available.


Staging of biliary atresia at diagnosis by molecular profiling of the liver.

Moyer K, Kaimal V, Pacheco C, Mourya R, Xu H, Shivakumar P, Chakraborty R, Rao M, Magee JC, Bove K, Aronow BJ, Jegga AG, Bezerra JA.

Genome Med. 2010 May 13;2(5):33. doi: 10.1186/gm154.


Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia.

Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, Chougnet CA.

J Hepatol. 2010 May;52(5):718-26. doi: 10.1016/j.jhep.2009.12.027. Epub 2010 Mar 5.


Structural similarity assessment for drug sensitivity prediction in cancer.

Shivakumar P, Krauthammer M.

BMC Bioinformatics. 2009 Sep 17;10 Suppl 9:S17. doi: 10.1186/1471-2105-10-S9-S17.


Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia.

Shivakumar P, Sabla GE, Whitington P, Chougnet CA, Bezerra JA.

J Clin Invest. 2009 Aug;119(8):2281-90.


Clinical presentation of mania compared with depression: data from a geriatric clinic in India.

Prakash O, Kumar CN, Shivakumar PT, Bharath S, Varghese M.

Int Psychogeriatr. 2009 Aug;21(4):764-7. doi: 10.1017/S1041610209009466. Epub 2009 Jun 4.


Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresia.

Erickson N, Mohanty SK, Shivakumar P, Sabla G, Chakraborty R, Bezerra JA.

Hepatology. 2008 May;47(5):1567-77. doi: 10.1002/hep.22229.


Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia.

Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, Stringer K, Caldwell C, Chougnet C, Bezerra JA.

Gastroenterology. 2007 Jul;133(1):268-77. Epub 2007 Apr 20.


A rare complication of jejunal diverticulosis.

Shanmugam RP, Shivakumar P.

Trop Gastroenterol. 2006 Jul-Sep;27(3):134-5.


Analysis of the biliary transcriptome in experimental biliary atresia.

Carvalho E, Liu C, Shivakumar P, Sabla G, Aronow B, Bezerra JA.

Gastroenterology. 2005 Aug;129(2):713-7.


NMR structural analysis of a peptide mimic of the bridging sheet of HIV-1 gp120 in methanol and water.

Chakraborty K, Shivakumar P, Raghothama S, Varadarajan R.

Biochem J. 2005 Sep 1;390(Pt 2):573-81.


Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia.

Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, McNeal MM, Ward RL, Bezerra JA.

J Clin Invest. 2004 Aug;114(3):322-9.


Biliary atresia and Th1 function: linking lymphocytes and bile ducts: commentary on the article by Mack et al. on page 79.

Shivakumar P, Bezerra JA.

Pediatr Res. 2004 Jul;56(1):9-10. Epub 2004 May 5. Review. No abstract available.


Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia.

Zhang DY, Sabla G, Shivakumar P, Tiao G, Sokol RJ, Mack C, Shneider BL, Aronow B, Bezerra JA.

Hepatology. 2004 Apr;39(4):954-62.


Numerical modelling of the perturbation of HIV-1 during combination anti-retroviral therapy.

Gumel AB, Loewen TD, Shivakumar PN, Sahai BM, Yu P, Garba ML.

Comput Biol Med. 2001 Sep;31(5):287-301.


Modelling of the heart and pericardium at end-diastole.

Shivakumar PN, Man CS, Rabkin SW.

J Biomech. 1989;22(3):201-9.


A case of pykno-dysostosis with psychosis.

Srinivas KN, Murali T, Shivakumar PS, Pandey RS, Arya BY.

Indian J Psychiatry. 1982 Apr;24(2):190-1.

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