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Items: 18

1.

Brain macrophages harbor latent, infectious simian immunodeficiency virus.

Abreu C, Shirk EN, Queen SE, Beck SE, Mangus LM, Pate KAM, Mankowski JL, Gama L, Clements JE.

AIDS. 2019 Dec 1;33 Suppl 2:S181-S188. doi: 10.1097/QAD.0000000000002269.

PMID:
31789817
2.

Myeloid and CD4 T Cells Comprise the Latent Reservoir in Antiretroviral Therapy-Suppressed SIVmac251-Infected Macaques.

Abreu CM, Veenhuis RT, Avalos CR, Graham S, Parrilla DR, Ferreira EA, Queen SE, Shirk EN, Bullock BT, Li M, Metcalf Pate KA, Beck SE, Mangus LM, Mankowski JL, Mac Gabhann F, O'Connor SL, Gama L, Clements JE.

mBio. 2019 Aug 20;10(4). pii: e01659-19. doi: 10.1128/mBio.01659-19.

3.

Infectious Virus Persists in CD4+ T Cells and Macrophages in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques.

Abreu CM, Veenhuis RT, Avalos CR, Graham S, Queen SE, Shirk EN, Bullock BT, Li M, Metcalf Pate KA, Beck SE, Mangus LM, Mankowski JL, Clements JE, Gama L.

J Virol. 2019 Jul 17;93(15). pii: e00065-19. doi: 10.1128/JVI.00065-19. Print 2019 Aug 1.

4.

A Quantitative Approach to SIV Functional Latency in Brain Macrophages.

Abreu C, Shirk EN, Queen SE, Mankowski JL, Gama L, Clements JE.

J Neuroimmune Pharmacol. 2019 Mar;14(1):23-32. doi: 10.1007/s11481-018-9803-8. Epub 2018 Aug 30. Review.

PMID:
30167896
5.

SIV Latency in Macrophages in the CNS.

Gama L, Abreu C, Shirk EN, Queen SE, Beck SE, Metcalf Pate KA, Bullock BT, Zink MC, Mankowski JL, Clements JE.

Curr Top Microbiol Immunol. 2018;417:111-130. doi: 10.1007/82_2018_89. Review.

6.

Lymphocyte-Dominant Encephalitis and Meningitis in Simian Immunodeficiency Virus-Infected Macaques Receiving Antiretroviral Therapy.

Mangus LM, Beck SE, Queen SE, Brill SA, Shirk EN, Metcalf Pate KA, Muth DC, Adams RJ, Gama L, Clements JE, Mankowski JL.

Am J Pathol. 2018 Jan;188(1):125-134. doi: 10.1016/j.ajpath.2017.08.035. Epub 2017 Dec 8.

7.

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir.

Avalos CR, Abreu CM, Queen SE, Li M, Price S, Shirk EN, Engle EL, Forsyth E, Bullock BT, Mac Gabhann F, Wietgrefe SW, Haase AT, Zink MC, Mankowski JL, Clements JE, Gama L.

mBio. 2017 Aug 15;8(4). pii: e01186-17. doi: 10.1128/mBio.01186-17.

8.

Toll-like receptor 2bright cells identify circulating monocytes in human and non-human primates.

Shirk EN, Kral BG, Gama L.

Cytometry A. 2017 Apr;91(4):364-371. doi: 10.1002/cyto.a.23098. Epub 2017 Mar 21.

9.

Distinct Patterns of Tryptophan Maintenance in Tissues during Kynurenine Pathway Activation in Simian Immunodeficiency Virus-Infected Macaques.

Drewes JL, Croteau JD, Shirk EN, Engle EL, Zink MC, Graham DR.

Front Immunol. 2016 Dec 19;7:605. doi: 10.3389/fimmu.2016.00605. eCollection 2016.

10.

Marked Enteropathy in an Accelerated Macaque Model of AIDS.

Croteau JD, Engle EL, Queen SE, Shirk EN, Zink MC.

Am J Pathol. 2017 Mar;187(3):589-604. doi: 10.1016/j.ajpath.2016.10.019. Epub 2017 Jan 3.

11.

Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques.

Gama L, Abreu CM, Shirk EN, Price SL, Li M, Laird GM, Pate KA, Wietgrefe SW, O'Connor SL, Pianowski L, Haase AT, Van Lint C, Siliciano RF, Clements JE; LRA-SIV Study Group.

AIDS. 2017 Jan 2;31(1):5-14.

12.

Splenic Damage during SIV Infection: Role of T-Cell Depletion and Macrophage Polarization and Infection.

Williams DW, Engle EL, Shirk EN, Queen SE, Gama L, Mankowski JL, Zink MC, Clements JE.

Am J Pathol. 2016 Aug;186(8):2068-2087. doi: 10.1016/j.ajpath.2016.03.019. Epub 2016 Jun 18.

13.

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques.

Avalos CR, Price SL, Forsyth ER, Pin JN, Shirk EN, Bullock BT, Queen SE, Li M, Gellerup D, O'Connor SL, Zink MC, Mankowski JL, Gama L, Clements JE.

J Virol. 2016 May 27;90(12):5643-5656. doi: 10.1128/JVI.00290-16. Print 2016 Jun 15.

14.

A Murine Viral Outgrowth Assay to Detect Residual HIV Type 1 in Patients With Undetectable Viral Loads.

Metcalf Pate KA, Pohlmeyer CW, Walker-Sperling VE, Foote JB, Najarro KM, Cryer CG, Salgado M, Gama L, Engle EL, Shirk EN, Queen SE, Chioma S, Vermillion MS, Bullock B, Li M, Lyons CE, Adams RJ, Zink MC, Clements JE, Mankowski JL, Blankson JN.

J Infect Dis. 2015 Nov 1;212(9):1387-96. doi: 10.1093/infdis/jiv230. Epub 2015 Apr 15.

15.

Combination fluconazole/paroxetine treatment is neuroprotective despite ongoing neuroinflammation and viral replication in an SIV model of HIV neurological disease.

Meulendyke KA, Queen SE, Engle EL, Shirk EN, Liu J, Steiner JP, Nath A, Tarwater PM, Graham DR, Mankowski JL, Zink MC.

J Neurovirol. 2014 Dec;20(6):591-602. doi: 10.1007/s13365-014-0283-1. Epub 2014 Sep 17.

16.

Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novo infection and activation of viral LTR.

Abreu CM, Price SL, Shirk EN, Cunha RD, Pianowski LF, Clements JE, Tanuri A, Gama L.

PLoS One. 2014 May 14;9(5):e97257. doi: 10.1371/journal.pone.0097257. eCollection 2014.

17.

Platelet activation and platelet-monocyte aggregate formation contribute to decreased platelet count during acute simian immunodeficiency virus infection in pig-tailed macaques.

Metcalf Pate KA, Lyons CE, Dorsey JL, Shirk EN, Queen SE, Adams RJ, Gama L, Morrell CN, Mankowski JL.

J Infect Dis. 2013 Sep;208(6):874-83. doi: 10.1093/infdis/jit278. Epub 2013 Jul 11.

18.

Expansion of a subset of CD14highCD16negCCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection.

Gama L, Shirk EN, Russell JN, Carvalho KI, Li M, Queen SE, Kalil J, Zink MC, Clements JE, Kallas EG.

J Leukoc Biol. 2012 May;91(5):803-16. doi: 10.1189/jlb.1111579. Epub 2012 Feb 24.

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