Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection.

Shirey KA, Perkins DJ, Lai W, Zhang W, Fernando LR, Gusovsky F, Blanco JCG, Vogel SN.

MBio. 2019 May 7;10(3). pii: e00810-19. doi: 10.1128/mBio.00810-19.

2.

Novel role of gastrin releasing peptide-mediated signaling in the host response to influenza infection.

Shirey KA, Sunday ME, Lai W, Patel MC, Blanco JCG, Cuttitta F, Vogel SN.

Mucosal Immunol. 2019 Jan;12(1):223-231. doi: 10.1038/s41385-018-0081-9. Epub 2018 Oct 16.

3.

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections.

Patel MC, Shirey KA, Boukhvalova MS, Vogel SN, Blanco JCG.

MBio. 2018 Mar 13;9(2). pii: e00246-18. doi: 10.1128/mBio.00246-18.

4.

Host-based lipid inflammation drives pathogenesis in Francisella infection.

Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12596-12601. doi: 10.1073/pnas.1712887114. Epub 2017 Nov 6.

5.

The θ-defensin retrocyclin 101 inhibits TLR4- and TLR2-dependent signaling and protects mice against influenza infection.

Prantner D, Shirey KA, Lai W, Lu W, Cole AM, Vogel SN, Garzino-Demo A.

J Leukoc Biol. 2017 Oct;102(4):1103-1113. doi: 10.1189/jlb.2A1215-567RR. Epub 2017 Jul 20.

6.

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection.

Perrin-Cocon L, Aublin-Gex A, Sestito SE, Shirey KA, Patel MC, André P, Blanco JC, Vogel SN, Peri F, Lotteau V.

Sci Rep. 2017 Jan 20;7:40791. doi: 10.1038/srep40791.

7.

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.

Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH.

PLoS Pathog. 2016 Aug 2;12(8):e1005803. doi: 10.1371/journal.ppat.1005803. eCollection 2016 Aug.

8.

Enhanced allergic responsiveness after early childhood infection with respiratory viruses: Are long-lived alternatively activated macrophages the missing link?

Keegan AD, Shirey KA, Bagdure D, Blanco J, Viscardi RM, Vogel SN.

Pathog Dis. 2016 Jul;74(5). pii: ftw047. doi: 10.1093/femspd/ftw047. Epub 2016 May 12.

9.

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.

Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, Pedra JHF.

Infect Immun. 2016 May 24;84(6):1796-1805. doi: 10.1128/IAI.01526-15. Print 2016 Jun.

10.

Novel strategies for targeting innate immune responses to influenza.

Shirey KA, Lai W, Patel MC, Pletneva LM, Pang C, Kurt-Jones E, Lipsky M, Roger T, Calandra T, Tracey KJ, Al-Abed Y, Bowie AG, Fasano A, Dinarello CA, Gusovsky F, Blanco JC, Vogel SN.

Mucosal Immunol. 2016 Sep;9(5):1173-82. doi: 10.1038/mi.2015.141. Epub 2016 Jan 27.

11.

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza.

Piao W, Shirey KA, Ru LW, Lai W, Szmacinski H, Snyder GA, Sundberg EJ, Lakowicz JR, Vogel SN, Toshchakov VY.

Cell Rep. 2015 Jun 30;11(12):1941-52. doi: 10.1016/j.celrep.2015.05.035. Epub 2015 Jun 18.

12.

Novel drugs targeting Toll-like receptors for antiviral therapy.

Patel MC, Shirey KA, Pletneva LM, Boukhvalova MS, Garzino-Demo A, Vogel SN, Blanco JC.

Future Virol. 2014 Sep;9(9):811-829.

13.

Macrophage activation and polarization: nomenclature and experimental guidelines.

Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA.

Immunity. 2014 Jul 17;41(1):14-20. doi: 10.1016/j.immuni.2014.06.008.

14.

Agents that increase AAM differentiation blunt RSV-mediated lung pathology.

Shirey KA, Lai W, Pletneva LM, Finkelman FD, Feola DJ, Blanco JC, Vogel SN.

J Leukoc Biol. 2014 Dec;96(6):951-5. doi: 10.1189/jlb.4HI0414-226R. Epub 2014 Jul 9.

15.

A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.

Blanco JC, Boukhvalova MS, Pletneva LM, Shirey KA, Vogel SN.

Vaccine. 2014 Mar 14;32(13):1495-500. doi: 10.1016/j.vaccine.2013.11.032. Epub 2013 Nov 16.

16.

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology.

Shirey KA, Lai W, Pletneva LM, Karp CL, Divanovic S, Blanco JC, Vogel SN.

Mucosal Immunol. 2014 May;7(3):549-57. doi: 10.1038/mi.2013.71. Epub 2013 Sep 25.

17.

Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15.

Doyle SL, Shirey KA, McGettrick AF, Kenny EF, Carpenter S, Caffrey BE, Gargan S, Quinn SR, Caamaño JH, Moynagh P, Vogel SN, O'Neill LA.

J Biol Chem. 2013 Aug 30;288(35):25066-75. doi: 10.1074/jbc.M113.469122. Epub 2013 Jul 19.

18.

The TLR4 antagonist Eritoran protects mice from lethal influenza infection.

Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, Vogel SN.

Nature. 2013 May 23;497(7450):498-502. doi: 10.1038/nature12118. Epub 2013 May 1.

19.

Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1.

Qualls JE, Subramanian C, Rafi W, Smith AM, Balouzian L, DeFreitas AA, Shirey KA, Reutterer B, Kernbauer E, Stockinger S, Decker T, Miyairi I, Vogel SN, Salgame P, Rock CO, Murray PJ.

Cell Host Microbe. 2012 Sep 13;12(3):313-23. doi: 10.1016/j.chom.2012.07.012.

20.

Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.

Rallabhandi P, Phillips RL, Boukhvalova MS, Pletneva LM, Shirey KA, Gioannini TL, Weiss JP, Chow JC, Hawkins LD, Vogel SN, Blanco JC.

MBio. 2012 Aug 7;3(4). pii: e00218-12. doi: 10.1128/mBio.00218-12. Print 2012.

21.

Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists.

Polumuri SK, Jayakar GG, Shirey KA, Roberts ZJ, Perkins DJ, Pitha PM, Vogel SN.

J Immunol. 2012 Jul 1;189(1):50-60. doi: 10.4049/jimmunol.1003554. Epub 2012 May 25.

22.

Members of the Francisella tularensis phagosomal transporter subfamily of major facilitator superfamily transporters are critical for pathogenesis.

Marohn ME, Santiago AE, Shirey KA, Lipsky M, Vogel SN, Barry EM.

Infect Immun. 2012 Jul;80(7):2390-401. doi: 10.1128/IAI.00144-12. Epub 2012 Apr 16.

23.

Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza.

Chen WH, Toapanta FR, Shirey KA, Zhang L, Giannelou A, Page C, Frieman MB, Vogel SN, Cross AS.

Immunol Lett. 2012 Jan 30;141(2):227-34. doi: 10.1016/j.imlet.2011.10.009. Epub 2011 Oct 20.

24.

Role of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge.

Cole LE, Mann BJ, Shirey KA, Richard K, Yang Y, Gearhart PJ, Chesko KL, Viscardi RM, Vogel SN.

J Leukoc Biol. 2011 Oct;90(4):787-97. doi: 10.1189/jlb.0111014. Epub 2011 Jul 12.

25.

Proteinase-activated receptor 2 activation promotes an anti-inflammatory and alternatively activated phenotype in LPS-stimulated murine macrophages.

Nhu QM, Shirey KA, Pennini ME, Stiltz J, Vogel SN.

Innate Immun. 2012 Apr;18(2):193-203. doi: 10.1177/1753425910395044. Epub 2011 Jan 14.

26.

The anti-tumor agent, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), induces IFN-beta-mediated antiviral activity in vitro and in vivo.

Shirey KA, Nhu QM, Yim KC, Roberts ZJ, Teijaro JR, Farber DL, Blanco JC, Vogel SN.

J Leukoc Biol. 2011 Mar;89(3):351-7. doi: 10.1189/jlb.0410216. Epub 2010 Nov 17.

27.

New insights for development of a safe and protective RSV vaccine.

Blanco JC, Boukhvalova MS, Shirey KA, Prince GA, Vogel SN.

Hum Vaccin. 2010 Jun;6(6):482-92. Epub 2010 Jun 1. Review.

28.

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent.

Shirey KA, Pletneva LM, Puche AC, Keegan AD, Prince GA, Blanco JC, Vogel SN.

Mucosal Immunol. 2010 May;3(3):291-300. doi: 10.1038/mi.2010.6. Epub 2010 Mar 10.

29.

Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.

Cole LE, Laird MH, Seekatz A, Santiago A, Jiang Z, Barry E, Shirey KA, Fitzgerald KA, Vogel SN.

J Leukoc Biol. 2010 Feb;87(2):275-81. doi: 10.1189/jlb.0909619. Epub 2009 Nov 4.

30.

Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.

Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD.

Sci Signal. 2008 Dec 23;1(51):ra17. doi: 10.1126/scisignal.1164795.

31.

An essential role for the antiviral endoribonuclease, RNase-L, in antibacterial immunity.

Li XL, Ezelle HJ, Kang TJ, Zhang L, Shirey KA, Harro J, Hasday JD, Mohapatra SK, Crasta OR, Vogel SN, Cross AS, Hassel BA.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20816-21. doi: 10.1073/pnas.0807265105. Epub 2008 Dec 15.

32.

Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism.

Shirey KA, Cole LE, Keegan AD, Vogel SN.

J Immunol. 2008 Sep 15;181(6):4159-67.

33.

Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways.

Cole LE, Santiago A, Barry E, Kang TJ, Shirey KA, Roberts ZJ, Elkins KL, Cross AS, Vogel SN.

J Immunol. 2008 May 15;180(10):6885-91.

34.

Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages.

Cole LE, Shirey KA, Barry E, Santiago A, Rallabhandi P, Elkins KL, Puche AC, Michalek SM, Vogel SN.

Infect Immun. 2007 Aug;75(8):4127-37. Epub 2007 May 21.

37.

Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells.

Shirey KA, Jung JY, Maeder GS, Carlin JM.

J Interferon Cytokine Res. 2006 Jan;26(1):53-62.

38.

Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha.

Robinson CM, Shirey KA, Carlin JM.

J Interferon Cytokine Res. 2003 Aug;23(8):413-21.

Supplemental Content

Loading ...
Support Center