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Items: 19


Leu72Met and Other Intronic Polymorphisms in the GHRL and GHSR Genes Are Not Associated with Type 2 Diabetes Mellitus, Insulin Resistance, or Serum Ghrelin Levels in a Saudi Population.

Joatar FE, Al Qarni AA, Ali ME, Al Masaud A, Shire AM, Das N, Gumaa K, Giha HA.

Endocrinol Metab (Seoul). 2017 Sep;32(3):360-369. doi: 10.3803/EnM.2017.32.3.360.


Association of Plasma Ghrelin Levels with Insulin Resistance in Type 2 Diabetes Mellitus among Saudi Subjects.

Al Qarni AA, Joatar FE, Das N, Awad M, Eltayeb M, Al-Zubair AG, Ali ME, Al Masaud A, Shire AM, Gumaa K, Giha HA.

Endocrinol Metab (Seoul). 2017 Jun;32(2):230-240. doi: 10.3803/EnM.2017.32.2.230. Epub 2017 May 29.


Methylated Bone Morphogenetic Protein 3 (BMP3) Gene: Evaluation of Tumor Suppressor Function and Biomarker Potential in Biliary Cancer.

Kisiel JB, Li J, Zou H, Oseini AM, Strauss BB, Gulaid KH, Moser CD, Aderca I, Ahlquist DA, Roberts LR, Shire AM.

J Mol Biomark Diagn. 2013 Aug 3;4(145):1000145.


Completion of the human papillomavirus vaccination series lags in Somali adolescents.

Pruitt CN, Reese CS, Grossardt BR, Shire AM, Creedon DJ.

J Low Genit Tract Dis. 2013 Jul;17(3):280-8. doi: 10.1097/LGT.0b013e3182759a64.


The transcription factor GLI1 mediates TGFβ1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism.

Zheng X, Vittar NB, Gai X, Fernandez-Barrena MG, Moser CD, Hu C, Almada LL, McCleary-Wheeler AL, Elsawa SF, Vrabel AM, Shire AM, Comba A, Thorgeirsson SS, Kim Y, Liu Q, Fernandez-Zapico ME, Roberts LR.

PLoS One. 2012;7(11):e49581. doi: 10.1371/journal.pone.0049581. Epub 2012 Nov 19.


The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling.

Zheng X, Gai X, Han S, Moser CD, Hu C, Shire AM, Floyd RA, Roberts LR.

Genes Chromosomes Cancer. 2013 Mar;52(3):225-36. doi: 10.1002/gcc.22022. Epub 2012 Oct 29.


Prevention of hepatocellular carcinoma: progress and challenges.

Shire AM, Roberts LR.

Minerva Gastroenterol Dietol. 2012 Mar;58(1):49-64. Review.


Viral hepatitis among Somali immigrants in Minnesota: association of hepatitis C with hepatocellular carcinoma.

Shire AM, Sandhu DS, Kaiya JK, Oseini AM, Yang JD, Chaiteerakij R, Mettler TA, Giama NH, Roberts RO, Therneau TM, Petersen GM, Knutson KL, Roberts LR.

Mayo Clin Proc. 2012 Jan;87(1):17-24. doi: 10.1016/j.mayocp.2011.08.001.


Occult hepatitis B virus infection: bit player or role player?

Shire AM, Roberts LR.

Hepatology. 2011 Sep 2;54(3):760-3. doi: 10.1002/hep.24528. No abstract available.


Utility of serum immunoglobulin G4 in distinguishing immunoglobulin G4-associated cholangitis from cholangiocarcinoma.

Oseini AM, Chaiteerakij R, Shire AM, Ghazale A, Kaiya J, Moser CD, Aderca I, Mettler TA, Therneau TM, Zhang L, Takahashi N, Chari ST, Roberts LR.

Hepatology. 2011 Sep 2;54(3):940-8. doi: 10.1002/hep.24487. Epub 2011 Aug 8.


Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors.

Lai JP, Sandhu DS, Yu C, Moser CD, Hu C, Shire AM, Aderca I, Murphy LM, Adjei AA, Sanderson S, Roberts LR.

Liver Int. 2010 Nov;30(10):1522-8. doi: 10.1111/j.1478-3231.2010.02336.x. Epub 2010 Sep 8.


The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.

Lai JP, Oseini AM, Moser CD, Yu C, Elsawa SF, Hu C, Nakamura I, Han T, Aderca I, Isomoto H, Garrity-Park MM, Shire AM, Li J, Sanderson SO, Adjei AA, Fernandez-Zapico ME, Roberts LR.

Hepatology. 2010 Nov;52(5):1680-9. doi: 10.1002/hep.23848.


Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo.

Lai JP, Sandhu DS, Moser CD, Cazanave SC, Oseini AM, Shire AM, Shridhar V, Sanderson SO, Roberts LR.

J Hepatol. 2009 Jun;50(6):1112-21. doi: 10.1016/j.jhep.2008.12.031. Epub 2009 Mar 9.


The tumor suppressor function of human sulfatase 1 (SULF1) in carcinogenesis.

Lai JP, Sandhu DS, Shire AM, Roberts LR.

J Gastrointest Cancer. 2008;39(1-4):149-58. doi: 10.1007/s12029-009-9058-y. Epub 2009 Apr 17. Review.


Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.

Lai JP, Sandhu DS, Yu C, Han T, Moser CD, Jackson KK, Guerrero RB, Aderca I, Isomoto H, Garrity-Park MM, Zou H, Shire AM, Nagorney DM, Sanderson SO, Adjei AA, Lee JS, Thorgeirsson SS, Roberts LR.

Hepatology. 2008 Apr;47(4):1211-22. doi: 10.1002/hep.22202.


Highly methylated genes in colorectal neoplasia: implications for screening.

Zou H, Harrington JJ, Shire AM, Rego RL, Wang L, Campbell ME, Oberg AL, Ahlquist DA.

Cancer Epidemiol Biomarkers Prev. 2007 Dec;16(12):2686-96.


SINE elements of Entamoeba dispar.

Shire AM, Ackers JP.

Mol Biochem Parasitol. 2007 Mar;152(1):47-52. Epub 2006 Dec 8.


Ethnic variation in AMD-associated complement factor H polymorphism p.Tyr402His.

Grassi MA, Fingert JH, Scheetz TE, Roos BR, Ritch R, West SK, Kawase K, Shire AM, Mullins RF, Stone EM.

Hum Mutat. 2006 Sep;27(9):921-5.


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