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Items: 45


ZNFX-1 Functions within Perinuclear Nuage to Balance Epigenetic Signals.

Ishidate T, Ozturk AR, Durning DJ, Sharma R, Shen EZ, Chen H, Seth M, Shirayama M, Mello CC.

Mol Cell. 2018 May 17;70(4):639-649.e6. doi: 10.1016/j.molcel.2018.04.009.


A Sex Chromosome piRNA Promotes Robust Dosage Compensation and Sex Determination in C. elegans.

Tang W, Seth M, Tu S, Shen EZ, Li Q, Shirayama M, Weng Z, Mello CC.

Dev Cell. 2018 Mar 26;44(6):762-770.e3. doi: 10.1016/j.devcel.2018.01.025. Epub 2018 Feb 15.


The Coding Regions of Germline mRNAs Confer Sensitivity to Argonaute Regulation in C. elegans.

Seth M, Shirayama M, Tang W, Shen EZ, Tu S, Lee HC, Weng Z, Mello CC.

Cell Rep. 2018 Feb 27;22(9):2254-2264. doi: 10.1016/j.celrep.2018.02.009. Epub 2018 Feb 15.


Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline.

Shen EZ, Chen H, Ozturk AR, Tu S, Shirayama M, Tang W, Ding YH, Dai SY, Weng Z, Mello CC.

Cell. 2018 Feb 22;172(5):937-951.e18. doi: 10.1016/j.cell.2018.02.002. Epub 2018 Feb 15.


The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4.

Gnazzo MM, Uhlemann EE, Villarreal AR, Shirayama M, Dominguez EG, Skop AR.

Mol Biol Cell. 2016 Oct 15;27(20):3052-3064. Epub 2016 Aug 24.


Dynamic prediction model and risk assessment chart for cardiovascular disease based on on-treatment blood pressure and baseline risk factors.

Teramukai S, Okuda Y, Miyazaki S, Kawamori R, Shirayama M, Teramoto T.

Hypertens Res. 2016 Feb;39(2):113-8. doi: 10.1038/hr.2015.120. Epub 2015 Nov 26.


POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA.

Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T, Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC.

Dev Cell. 2015 Jul 6;34(1):108-18. doi: 10.1016/j.devcel.2015.05.024. Epub 2015 Jun 18.


Lipid and blood pressure control for the prevention of cardiovascular disease in hypertensive patients: a subanalysis of the OMEGA study.

Teramoto T, Kawamori R, Miyazaki S, Teramukai S, Sato Y, Okuda Y, Shirayama M.

J Atheroscler Thromb. 2015;22(1):62-75. doi: 10.5551/jat.25304. Epub 2014 Aug 29.


A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans.

Kim H, Ishidate T, Ghanta KS, Seth M, Conte D Jr, Shirayama M, Mello CC.

Genetics. 2014 Aug;197(4):1069-80. doi: 10.1534/genetics.114.166389. Epub 2014 May 30.


The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans.

Shirayama M, Stanney W 3rd, Gu W, Seth M, Mello CC.

Curr Biol. 2014 Apr 14;24(8):845-51. doi: 10.1016/j.cub.2014.03.008. Epub 2014 Mar 27.


Divide and differentiate: CDK/Cyclins and the art of development.

Ishidate T, Elewa A, Kim S, Mello CC, Shirayama M.

Cell Cycle. 2014;13(9):1384-91. doi: 10.4161/cc.28656. Epub 2014 Mar 26. Review.


Inductive asymmetric cell division: The WRM leads the way.

Ishidate T, Kim S, Mello C, Shirayama M.

Worm. 2013 Oct 1;2(4):e26276. doi: 10.4161/worm.26276. Epub 2013 Sep 5. Review.


The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.

Seth M, Shirayama M, Gu W, Ishidate T, Conte D Jr, Mello CC.

Dev Cell. 2013 Dec 23;27(6):656-63.


Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans.

Conine CC, Moresco JJ, Gu W, Shirayama M, Conte D Jr, Yates JR 3rd, Mello CC.

Cell. 2013 Dec 19;155(7):1532-44. doi: 10.1016/j.cell.2013.11.032.


Study of sustained blood pressure-lowering effect of azelnidipine guided by self-measured morning and evening home blood pressure: subgroup analysis of the At-HOME study.

Kario K, Uehara Y, Shirayama M, Takahashi M, Shiosakai K, Hiramatsu K, Komiya M, Shimada K.

Drugs R D. 2013 Mar;13(1):75-85. doi: 10.1007/s40268-013-0007-7.


Inhibitory effects of azelnidipine tablets on morning hypertension.

Kario K, Sato Y, Shirayama M, Takahashi M, Shiosakai K, Hiramatsu K, Komiya M, Shimada K.

Drugs R D. 2013 Mar;13(1):63-73. doi: 10.1007/s40268-013-0006-8.


Wnt and CDK-1 regulate cortical release of WRM-1/β-catenin to control cell division orientation in early Caenorhabditis elegans embryos.

Kim S, Ishidate T, Sharma R, Soto MC, Conte D Jr, Mello CC, Shirayama M.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E918-27. doi: 10.1073/pnas.1300769110. Epub 2013 Feb 19.


Systematic genetic interaction screens uncover cell polarity regulators and functional redundancy.

Fievet BT, Rodriguez J, Naganathan S, Lee C, Zeiser E, Ishidate T, Shirayama M, Grill S, Ahringer J.

Nat Cell Biol. 2013 Jan;15(1):103-12. doi: 10.1038/ncb2639. Epub 2012 Dec 16.


Contribution of posterior corneal astigmatism to total corneal astigmatism.

Koch DD, Ali SF, Weikert MP, Shirayama M, Jenkins R, Wang L.

J Cataract Refract Surg. 2012 Dec;38(12):2080-7. doi: 10.1016/j.jcrs.2012.08.036. Epub 2012 Oct 12.


Relationship between achieved blood pressure, dietary habits and cardiovascular disease in hypertensive patients treated with olmesartan: the OMEGA study.

Teramoto T, Kawamori R, Miyazaki S, Teramukai S, Shirayama M, Hiramatsu K, Kobayashi F; OMEGA Study Group.

Hypertens Res. 2012 Dec;35(12):1136-44. doi: 10.1038/hr.2012.93. Epub 2012 Jul 5. Erratum in: Hypertens Res. 2012 Dec;35(12):1203.


piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.

Shirayama M, Seth M, Lee HC, Gu W, Ishidate T, Conte D Jr, Mello CC.

Cell. 2012 Jul 6;150(1):65-77. doi: 10.1016/j.cell.2012.06.015. Epub 2012 Jun 25.


C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts.

Lee HC, Gu W, Shirayama M, Youngman E, Conte D Jr, Mello CC.

Cell. 2012 Jul 6;150(1):78-87. doi: 10.1016/j.cell.2012.06.016. Epub 2012 Jun 25.


Optimizing intraocular lens power calculations in eyes with axial lengths above 25.0 mm.

Wang L, Shirayama M, Ma XJ, Kohnen T, Koch DD.

J Cataract Refract Surg. 2011 Nov;37(11):2018-27. doi: 10.1016/j.jcrs.2011.05.042.


Noninvasive assessment of tear stability with the tear stability analysis system in tear dysfunction patients.

Gumus K, Crockett CH, Rao K, Yeu E, Weikert MP, Shirayama M, Hada S, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2011 Jan 21;52(1):456-61. doi: 10.1167/iovs.10-5292. Print 2011 Jan.


Repeatability of corneal power and wavefront aberration measurements with a dual-Scheimpflug Placido corneal topographer.

Wang L, Shirayama M, Koch DD.

J Cataract Refract Surg. 2010 Mar;36(3):425-30. doi: 10.1016/j.jcrs.2009.09.034.


Argonautes ALG-3 and ALG-4 are required for spermatogenesis-specific 26G-RNAs and thermotolerant sperm in Caenorhabditis elegans.

Conine CC, Batista PJ, Gu W, Claycomb JM, Chaves DA, Shirayama M, Mello CC.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3588-93. doi: 10.1073/pnas.0911685107. Epub 2010 Feb 4.


NMY-2 maintains cellular asymmetry and cell boundaries, and promotes a SRC-dependent asymmetric cell division.

Liu J, Maduzia LL, Shirayama M, Mello CC.

Dev Biol. 2010 Mar 15;339(2):366-73. doi: 10.1016/j.ydbio.2009.12.041. Epub 2010 Jan 6.


The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation.

Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D Jr, Mello CC.

Cell. 2009 Oct 2;139(1):123-34. doi: 10.1016/j.cell.2009.09.014.


Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline.

Gu W, Shirayama M, Conte D Jr, Vasale J, Batista PJ, Claycomb JM, Moresco JJ, Youngman EM, Keys J, Stoltz MJ, Chen CC, Chaves DA, Duan S, Kasschau KD, Fahlgren N, Yates JR 3rd, Mitani S, Carrington JC, Mello CC.

Mol Cell. 2009 Oct 23;36(2):231-44. doi: 10.1016/j.molcel.2009.09.020. Epub 2009 Oct 1.


Comparison of corneal powers obtained from 4 different devices.

Shirayama M, Wang L, Weikert MP, Koch DD.

Am J Ophthalmol. 2009 Oct;148(4):528-535.e1. doi: 10.1016/j.ajo.2009.04.028. Epub 2009 Jul 9.


The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans.

Shirayama M, Soto MC, Ishidate T, Kim S, Nakamura K, Bei Y, van den Heuvel S, Mello CC.

Curr Biol. 2006 Jan 10;16(1):47-55. Epub 2005 Dec 15.


Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos.

Nakamura K, Kim S, Ishidate T, Bei Y, Pang K, Shirayama M, Trzepacz C, Brownell DR, Mello CC.

Genes Dev. 2005 Aug 1;19(15):1749-54.


Artificial life simulation of self-assembly in bacteriophage by movable finite automata.

Shirayama M, Koshino M, Hatakeyama T, Kimura H.

Biosystems. 2004 Nov;77(1-3):151-61.


The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos.

Pang KM, Ishidate T, Nakamura K, Shirayama M, Trzepacz C, Schubert CM, Priess JR, Mello CC.

Dev Biol. 2004 Jan 1;265(1):127-39.


The psychological aspects of patients with delayed sleep phase syndrome (DSPS).

Shirayama M, Shirayama Y, Iida H, Kato M, Kajimura N, Watanabe T, Sekimoto M, Shirakawa S, Okawa M, Takahashi K.

Sleep Med. 2003 Sep;4(5):427-33.


Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

Ciosk R, Shirayama M, Shevchenko A, Tanaka T, Toth A, Shevchenko A, Nasmyth K.

Mol Cell. 2000 Feb;5(2):243-54.


APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

Shirayama M, Tóth A, Gálová M, Nasmyth K.

Nature. 1999 Nov 11;402(6758):203-7.


[Factors involved in termination of M phase].

Shirayama M, Matsui Y, Toh-e A.

Tanpakushitsu Kakusan Koso. 1994 Sep;39(12):2163-7. Review. Japanese. No abstract available.


Isolation of a CDC25 family gene, MSI2/LTE1, as a multicopy suppressor of ira1.

Shirayama M, Matsui Y, Tanaka K, Toh-e A.

Yeast. 1994 Apr;10(4):451-61.


MSI3, a multicopy suppressor of mutants hyperactivated in the RAS-cAMP pathway, encodes a novel HSP70 protein of Saccharomyces cerevisiae.

Shirayama M, Kawakami K, Matsui Y, Tanaka K, Toh-e A.

Mol Gen Genet. 1993 Sep;240(3):323-32.


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