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Items: 1 to 50 of 208

1.

A novel compound, ferulic acid-bound resveratrol, induces the tumor suppressor gene p15 and inhibits the three-dimensional proliferation of colorectal cancer cells.

Sawata Y, Matsukawa T, Doi S, Tsunoda T, Arikawa N, Matsunaga N, Ohnuki K, Shirasawa S, Kotake Y.

Mol Cell Biochem. 2019 Aug 22. doi: 10.1007/s11010-019-03606-8. [Epub ahead of print]

PMID:
31440879
2.

Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver.

Doi K, Tsunoda T, Koyanagi M, Tanaka Y, Yamano S, Fujikane A, Nishi K, Ishikura S, Shirasawa S.

Anticancer Res. 2019 Aug;39(8):4495-4502. doi: 10.21873/anticanres.13625.

PMID:
31366551
3.

Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation.

Charitou T, Srihari S, Lynn MA, Jarboui MA, Fasterius E, Moldovan M, Shirasawa S, Tsunoda T, Ueffing M, Xie J, Xin J, Wang X, Proud CG, Boldt K, Al-Khalili Szigyarto C, Kolch W, Lynn DJ.

Br J Cancer. 2019 Jul;121(1):37-50. doi: 10.1038/s41416-019-0477-7. Epub 2019 May 28.

PMID:
31133691
4.

Effect of hip fracture surgery within 24 hours on short-term mobility.

Ogawa T, Aoki T, Shirasawa S.

J Orthop Sci. 2019 May;24(3):469-473. doi: 10.1016/j.jos.2018.11.001. Epub 2018 Nov 28.

PMID:
30502228
5.

Distal locking screw length for volar locking plate fixation of distal radius fractures: Postoperative stability of full-length unicortical versus shorter screws.

Seki Y, Aoki T, Maehara H, Shirasawa S.

Hand Surg Rehabil. 2019 Feb;38(1):28-33. doi: 10.1016/j.hansur.2018.10.246. Epub 2018 Dec 1.

PMID:
30509732
6.

Acquisition of resistance to vemurafenib leads to interleukin-10 production through an aberrant activation of Akt in a melanoma cell line.

Inozume T, Tsunoda T, Morisaki T, Harada K, Shirasawa S, Kawamura T.

J Dermatol. 2018 Dec;45(12):1434-1439. doi: 10.1111/1346-8138.14651. Epub 2018 Sep 17.

PMID:
30222203
7.

Zfat expression in ZsGreen reporter gene knock‑in mice: Implications for a novel function of Zfat in definitive erythropoiesis.

Tsunoda T, Doi K, Ishikura S, Luo H, Nishi K, Matsuzaki H, Koyanagi M, Tanaka Y, Okamura T, Shirasawa S.

Int J Mol Med. 2018 Nov;42(5):2595-2603. doi: 10.3892/ijmm.2018.3806. Epub 2018 Aug 3.

8.

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models.

Del Curatolo A, Conciatori F, Cesta Incani U, Bazzichetto C, Falcone I, Corbo V, D'Agosto S, Eramo A, Sette G, Sperduti I, De Luca T, Marabese M, Shirasawa S, De Maria R, Scarpa A, Broggini M, Del Bufalo D, Cognetti F, Milella M, Ciuffreda L.

J Exp Clin Cancer Res. 2018 Jul 9;37(1):140. doi: 10.1186/s13046-018-0820-5.

9.

Growth Suppression of Human Colorectal Cancer Cells with Mutated KRAS by 3-Deaza-cytarabine in 3D Floating Culture.

Luo H, Nishi K, Ishikura S, Swain A, Morishige N, Yazaki R, Ohshima T, Shirasawa S, Tsunoda T.

Anticancer Res. 2018 Jul;38(7):4247-4256. doi: 10.21873/anticanres.12721.

PMID:
29970558
10.

In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer.

Wei R, Wong JPC, Lyu P, Xi X, Tong O, Zhang SD, Yuen HF, Shirasawa S, Kwok HF.

J Cell Mol Med. 2018 Sep;22(9):4097-4105. doi: 10.1111/jcmm.13686. Epub 2018 May 30.

11.

Conservative treatment in displaced fractures of the humeral capitellum: a reduction technique under local anaesthesia.

Ogawa T, Shirasawa S.

BMJ Case Rep. 2018 Apr 17;2018. pii: bcr-2017-223820. doi: 10.1136/bcr-2017-223820.

PMID:
29666087
12.

The Long Noncoding RNA OIP5-AS1 Is Involved in the Regulation of Cell Proliferation.

Naemura M, Kuroki M, Tsunoda T, Arikawa N, Sawata Y, Shirasawa S, Kotake Y.

Anticancer Res. 2018 Jan;38(1):77-81.

PMID:
29277759
13.

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line.

Nishi K, Iwaihara Y, Tsunoda T, Doi K, Sakata T, Shirasawa S, Ishikura S.

Cell Death Dis. 2017 Dec 14;8(12):3218. doi: 10.1038/s41419-017-0006-7.

14.

A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.

Okamoto H, Matsukawa T, Doi S, Tsunoda T, Sawata Y, Naemura M, Ohnuki K, Shirasawa S, Kotake Y.

Mol Cell Biochem. 2018 May;442(1-2):39-45. doi: 10.1007/s11010-017-3191-x. Epub 2017 Sep 21.

PMID:
28936721
15.

Oncogenic RAS-induced downregulation of ATG12 is required for survival of malignant intestinal epithelial cells.

Yoo BH, Khan IA, Koomson A, Gowda P, Sasazuki T, Shirasawa S, Gujar S, Rosen KV.

Autophagy. 2018;14(1):134-151. doi: 10.1080/15548627.2017.1370171. Epub 2017 Dec 21.

16.

Endoscopic Stalk Resection of a Toe Ganglion With Color-aided Visualization.

Ogawa T, Seki Y, Shirasawa S.

Arthrosc Tech. 2017 May 29;6(3):e673-e678. doi: 10.1016/j.eats.2017.03.030. eCollection 2017 Jun.

17.

An Alpha-kinase 2 Gene Variant Disrupts Filamentous Actin Localization in the Surface Cells of Colorectal Cancer Spheroids.

Nishi K, Luo H, Nakabayashi K, Doi K, Ishikura S, Iwaihara Y, Yoshida Y, Tanisawa K, Arai T, Mori S, Sawabe M, Muramatsu M, Tanaka M, Sakata T, Shirasawa S, Tsunoda T.

Anticancer Res. 2017 Jul;37(7):3855-3862.

PMID:
28668886
18.

Apremilast Induces Apoptosis of Human Colorectal Cancer Cells with Mutant KRAS.

Nishi K, Luo H, Ishikura S, Doi K, Iwaihara Y, Wills L, Baillie GS, Sakata T, Shirasawa S, Tsunoda T.

Anticancer Res. 2017 Jul;37(7):3833-3839.

PMID:
28668883
19.

MACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers.

Radhakrishnan H, Ilm K, Walther W, Shirasawa S, Sasazuki T, Daniel PT, Gillissen B, Stein U.

Cancer Lett. 2017 Sep 10;403:231-245. doi: 10.1016/j.canlet.2017.06.020. Epub 2017 Jun 23.

PMID:
28649004
20.

MEK162 Enhances Antitumor Activity of 5-Fluorouracil and Trifluridine in KRAS-mutated Human Colorectal Cancer Cell Lines.

Gong J, Chen Y, Yang L, Pillai R, Shirasawa S, Fakih M.

Anticancer Res. 2017 Jun;37(6):2831-2838.

PMID:
28551618
21.

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

Tajiri H, Uruno T, Shirai T, Takaya D, Matsunaga S, Setoyama D, Watanabe M, Kukimoto-Niino M, Oisaki K, Ushijima M, Sanematsu F, Honma T, Terada T, Oki E, Shirasawa S, Maehara Y, Kang D, Côté JF, Yokoyama S, Kanai M, Fukui Y.

Cell Rep. 2017 May 2;19(5):969-980. doi: 10.1016/j.celrep.2017.04.016.

22.

Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.

Kalimutho M, Bain AL, Mukherjee B, Nag P, Nanayakkara DM, Harten SK, Harris JL, Subramanian GN, Sinha D, Shirasawa S, Srihari S, Burma S, Khanna KK.

Mol Oncol. 2017 May;11(5):470-490. doi: 10.1002/1878-0261.12040. Epub 2017 Mar 27.

23.

Forced knee extension test is a manual test that correlates with the unstable feelings of patients with ACL injury before and after reconstruction.

Shirasawa S, Koga H, Horie M, Nakamura T, Watanabe T, Sekiya I, Muneta T.

Knee. 2016 Dec;23(6):1159-1163. doi: 10.1016/j.knee.2016.06.016. Epub 2016 Oct 29.

PMID:
28029577
24.

Plant Genome DataBase Japan (PGDBj).

Nakaya A, Ichihara H, Asamizu E, Shirasawa S, Nakamura Y, Tabata S, Hirakawa H.

Methods Mol Biol. 2017;1533:45-77.

PMID:
27987164
25.

Intellectual outcomes of extremely preterm infants at school age.

Asami M, Kamei A, Nakakarumai M, Shirasawa S, Akasaka M, Araya N, Tanifuji S, Chida S.

Pediatr Int. 2017 May;59(5):570-577. doi: 10.1111/ped.13215. Epub 2017 Mar 21.

PMID:
27935152
26.

Temporal brain metabolite changes in preterm infants with normal development.

Tanifuji S, Akasaka M, Kamei A, Araya N, Asami M, Matsumoto A, Sotodate G, Konishi Y, Shirasawa S, Toya Y, Kusano S, Chida S, Sasaki M, Matsuda T.

Brain Dev. 2017 Mar;39(3):196-202. doi: 10.1016/j.braindev.2016.10.006. Epub 2016 Nov 9.

PMID:
27838187
27.

Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.

Toda K, Kawada K, Iwamoto M, Inamoto S, Sasazuki T, Shirasawa S, Hasegawa S, Sakai Y.

Neoplasia. 2016 Nov;18(11):654-665. doi: 10.1016/j.neo.2016.09.004. Epub 2016 Oct 18.

28.

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells.

Ishikura S, Tsunoda T, Nakabayashi K, Doi K, Koyanagi M, Hayashi K, Kawai T, Tanaka Y, Iwaihara Y, Luo H, Nishi K, Okamura T, Shirasawa S.

Biochim Biophys Acta. 2016 Nov;1859(11):1398-1410. doi: 10.1016/j.bbagrm.2016.08.010. Epub 2016 Aug 31.

PMID:
27591365
29.

Myofibroma arising from a digital artery.

Seki Y, Shirasawa S.

J Orthop Sci. 2018 May;23(3):604-606. doi: 10.1016/j.jos.2016.07.002. Epub 2016 Jul 21. No abstract available.

PMID:
27452742
30.

DBA Lectin Binds to Highly Proliferative Mouse Erythroleukemia Cells.

Swain A, Kulkeaw K, Tanaka Y, Nakanishi Y, Shirasawa S, Sugiyama D.

Anticancer Res. 2016 Jul;36(7):3625-33.

PMID:
27354633
31.

Resveratrol Overcomes Cellular Resistance to Vemurafenib Through Dephosphorylation of AKT in BRAF-mutated Melanoma Cells.

Luo H, Umebayashi M, Doi K, Morisaki T, Shirasawa S, Tsunoda T.

Anticancer Res. 2016 Jul;36(7):3585-9.

PMID:
27354627
32.

The Nuclear Zinc Finger Protein Zfat Maintains FoxO1 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway.

Ishikura S, Iwaihara Y, Tanaka Y, Luo H, Nishi K, Doi K, Koyanagi M, Okamura T, Tsunoda T, Shirasawa S.

J Biol Chem. 2016 Jul 15;291(29):15282-91. doi: 10.1074/jbc.M116.723734. Epub 2016 May 20.

33.

In Hyperthermia Increased ERK and WNT Signaling Suppress Colorectal Cancer Cell Growth.

Bordonaro M, Shirasawa S, Lazarova DL.

Cancers (Basel). 2016 May 14;8(5). pii: E49. doi: 10.3390/cancers8050049.

34.

BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, Zografos G, Oikonomou E, Pintzas A.

Oncotarget. 2016 Feb 23;7(8):9188-221. doi: 10.18632/oncotarget.6942.

35.

ANRIL regulates the proliferation of human colorectal cancer cells in both two- and three-dimensional culture.

Naemura M, Tsunoda T, Inoue Y, Okamoto H, Shirasawa S, Kotake Y.

Mol Cell Biochem. 2016 Jan;412(1-2):141-6. doi: 10.1007/s11010-015-2618-5. Epub 2015 Dec 26.

PMID:
26708220
36.

Synthesis of New Congeners of 1-methyl-3-aminoisoquinolines, Evaluation of Their Cytotoxic Activity, In Silico and In Vitro Study of Their Molecular Targets as PDE4B.

Lapa GB, Tsunoda T, Shirasawa S, Baryshnikova MA, Evseev GG, Afanasyeva DA, Chigorina EA.

Chem Biol Drug Des. 2016 Apr;87(4):575-82. doi: 10.1111/cbdd.12691. Epub 2015 Dec 29.

PMID:
26613238
37.

Assessing Temporal Brain Metabolite Changes in Preterm Infants Using Multivoxel Magnetic Resonance Spectroscopy.

Akasaka M, Kamei A, Araya N, Matsumoto A, Konishi Y, Sotodate G, Shirasawa S, Toya Y, Kasai T, Chida S, Sasaki M.

Magn Reson Med Sci. 2016;15(2):187-92. doi: 10.2463/mrms.mp.2015-0041. Epub 2015 Nov 13.

38.

Embryonic Hematopoietic Progenitor Cells Reside in Muscle before Bone Marrow Hematopoiesis.

Tanaka Y, Inoue-Yokoo T, Kulkeaw K, Yanagi-Mizuochi C, Shirasawa S, Nakanishi Y, Sugiyama D.

PLoS One. 2015 Sep 21;10(9):e0138621. doi: 10.1371/journal.pone.0138621. eCollection 2015.

39.

EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer.

Dunne PD, Dasgupta S, Blayney JK, McArt DG, Redmond KL, Weir JA, Bradley CA, Sasazuki T, Shirasawa S, Wang T, Srivastava S, Ong CW, Arthur K, Salto-Tellez M, Wilson RH, Johnston PG, Van Schaeybroeck S.

Clin Cancer Res. 2016 Jan 1;22(1):230-242. doi: 10.1158/1078-0432.CCR-15-0603. Epub 2015 Aug 17.

40.

Apoptosis-inducing Factor, Mitochondrion-associated 2, Regulates Klf1 in a Mouse Erythroleukemia Cell Line.

Kojima N, Tanaka Y, Kulkeaw K, Nakanishi Y, Shirasawa S, Sugiyama D.

Anticancer Res. 2015 Aug;35(8):4493-9.

PMID:
26168492
41.

Establishment of a Three-dimensional Floating Cell Culture System for Screening Drugs Targeting KRAS-mediated Signaling Molecules.

Tsunoda T, Ishikura S, Doi K, Iwaihara Y, Hidesima H, Luo H, Hirose Y, Shirasawa S.

Anticancer Res. 2015 Aug;35(8):4453-9.

PMID:
26168486
42.

Marked Reduction in FoxO1 Protein by its Enhanced Proteasomal Degradation in Zfat-deficient Peripheral T-Cells.

Iwaihara Y, Ishikura S, Doi K, Tsunoda T, Fujimoto T, Okamura T, Shirasawa S.

Anticancer Res. 2015 Aug;35(8):4419-23.

PMID:
26168481
43.

Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells.

Yoo BH, Zagryazhskaya A, Li Y, Koomson A, Khan IA, Sasazuki T, Shirasawa S, Rosen KV.

Autophagy. 2015;11(8):1230-46. doi: 10.1080/15548627.2015.1056968.

44.

Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT.

Tochio N, Umehara T, Nakabayashi K, Yoneyama M, Tsuda K, Shirouzu M, Koshiba S, Watanabe S, Kigawa T, Sasazuki T, Shirasawa S, Yokoyama S.

J Struct Funct Genomics. 2015 Jun;16(2):55-65. doi: 10.1007/s10969-015-9196-3. Epub 2015 Mar 24.

45.

Oncogenic Ras influences the expression of multiple lncRNAs.

Kotake Y, Naemura M, Kitagawa K, Niida H, Tsunoda T, Shirasawa S, Kitagawa M.

Cytotechnology. 2016 Aug;68(4):1591-6. doi: 10.1007/s10616-014-9834-9. Epub 2014 Dec 14.

46.

Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS.

Iwamoto M, Kawada K, Nakamoto Y, Itatani Y, Inamoto S, Toda K, Kimura H, Sasazuki T, Shirasawa S, Okuyama H, Inoue M, Hasegawa S, Togashi K, Sakai Y.

J Nucl Med. 2014 Dec;55(12):2038-44. doi: 10.2967/jnumed.114.142927. Epub 2014 Nov 5.

47.

Competition between human cells by entosis.

Sun Q, Luo T, Ren Y, Florey O, Shirasawa S, Sasazuki T, Robinson DN, Overholtzer M.

Cell Res. 2014 Nov;24(11):1299-310. doi: 10.1038/cr.2014.138. Epub 2014 Oct 24.

48.

Zfat-deficient CD4⁺ CD8⁺ double-positive thymocytes are susceptible to apoptosis with deregulated activation of p38 and JNK.

Ishikura S, Ogawa M, Doi K, Matsuzaki H, Iwaihara Y, Tanaka Y, Tsunoda T, Hideshima H, Okamura T, Shirasawa S.

J Cell Biochem. 2015 Jan;116(1):149-57. doi: 10.1002/jcb.24954.

PMID:
25169027
49.

Dok2 likely down-regulates Klf1 in mouse erythroleukemia cells.

Tanaka Y, Kulkeaw K, Inoue T, Tan KS, Nakanishi Y, Shirasawa S, Sugiyama D.

Anticancer Res. 2014 Aug;34(8):4561-7.

PMID:
25075100
50.

Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture.

Tsunoda T, Ishikura S, Doi K, Matsuzaki H, Iwaihara Y, Shirasawa S.

Anticancer Res. 2014 Aug;34(8):4551-5.

PMID:
25075098

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