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Items: 13

1.

Intracellular cholesterol level regulates sensitivity of glioblastoma cells against temozolomide-induced cell death by modulation of caspase-8 activation via death receptor 5-accumulation and activation in the plasma membrane lipid raft.

Yamamoto Y, Tomiyama A, Sasaki N, Yamaguchi H, Shirakihara T, Nakashima K, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Sakai R, Namba H, Mori K.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1292-1299. doi: 10.1016/j.bbrc.2017.11.113. Epub 2017 Nov 21.

PMID:
29162448
2.

The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.

Hoshi Y, Endo K, Shirakihara T, Fukagawa A, Miyazawa K, Saitoh M.

FEBS Lett. 2016 Jan;590(2):270-8. doi: 10.1002/1873-3468.12042. Epub 2016 Jan 27.

3.

Augmentation of invadopodia formation in temozolomide-resistant or adopted glioma is regulated by c-Jun terminal kinase-paxillin axis.

Ueno H, Tomiyama A, Yamaguchi H, Uekita T, Shirakihara T, Nakashima K, Otani N, Wada K, Sakai R, Arai H, Mori K.

Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):240-7. doi: 10.1016/j.bbrc.2015.10.122. Epub 2015 Oct 27.

PMID:
26518652
4.

Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.

Shirakihara T, Kawasaki T, Fukagawa A, Semba K, Sakai R, Miyazono K, Miyazawa K, Saitoh M.

Cancer Sci. 2013 Sep;104(9):1189-97. doi: 10.1111/cas.12220. Epub 2013 Jul 20.

5.

Basolateral BMP signaling in polarized epithelial cells.

Saitoh M, Shirakihara T, Fukasawa A, Horiguchi K, Sakamoto K, Sugiya H, Beppu H, Fujita Y, Morita I, Miyazono K, Miyazawa K.

PLoS One. 2013 May 13;8(5):e62659. doi: 10.1371/journal.pone.0062659. Print 2013.

6.

Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma.

Kitagawa N, Ojima H, Shirakihara T, Shimizu H, Kokubu A, Urushidate T, Totoki Y, Kosuge T, Miyagawa S, Shibata T.

Cancer Sci. 2013 May;104(5):543-51. doi: 10.1111/cas.12126. Epub 2013 Mar 20.

7.

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.

Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H, Nakamura Y, Tsunoda T, Shibata T, Nakagawa H.

Nat Genet. 2012 May 27;44(7):760-4. doi: 10.1038/ng.2291.

PMID:
22634756
8.

High-resolution characterization of a hepatocellular carcinoma genome.

Totoki Y, Tatsuno K, Yamamoto S, Arai Y, Hosoda F, Ishikawa S, Tsutsumi S, Sonoda K, Totsuka H, Shirakihara T, Sakamoto H, Wang L, Ojima H, Shimada K, Kosuge T, Okusaka T, Kato K, Kusuda J, Yoshida T, Aburatani H, Shibata T.

Nat Genet. 2011 May;43(5):464-9. doi: 10.1038/ng.804. Epub 2011 Apr 17.

PMID:
21499249
9.

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition.

Shirakihara T, Horiguchi K, Miyazawa K, Ehata S, Shibata T, Morita I, Miyazono K, Saitoh M.

EMBO J. 2011 Feb 16;30(4):783-95. doi: 10.1038/emboj.2010.351. Epub 2011 Jan 11.

10.

Regulation of the stability of cell surface E-cadherin by the proteasome.

Saitoh M, Shirakihara T, Miyazono K.

Biochem Biophys Res Commun. 2009 Apr 17;381(4):560-5. doi: 10.1016/j.bbrc.2009.02.098. Epub 2009 Feb 24.

PMID:
19245796
11.

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

Horiguchi K, Shirakihara T, Nakano A, Imamura T, Miyazono K, Saitoh M.

J Biol Chem. 2009 Jan 2;284(1):245-53. doi: 10.1074/jbc.M804777200. Epub 2008 Nov 14.

12.
13.

A role for Id in the regulation of TGF-beta-induced epithelial-mesenchymal transdifferentiation.

Kondo M, Cubillo E, Tobiume K, Shirakihara T, Fukuda N, Suzuki H, Shimizu K, Takehara K, Cano A, Saitoh M, Miyazono K.

Cell Death Differ. 2004 Oct;11(10):1092-101.

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