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A Powderization Process for Encapsulating with Functional Biomaterials Using Nozzleless Electrostatic Atomization.

Mori C, Kadota K, Shimosaka A, Yoshida M, Shirakawa Y.

J Food Sci. 2019 Sep;84(9):2482-2489. doi: 10.1111/1750-3841.14783. Epub 2019 Sep 2.


Early inappropriate shock in a subcutaneous cardiac defibrillator due to subcutaneous air.

Nishinarita R, Kishihara J, Matsuura G, Arakawa Y, Kobayashi S, Shirakawa Y, Horiguchi A, Nakamura H, Ishizue N, Oikawa J, Fukaya H, Niwano S, Ako J.

J Arrhythm. 2019 Jun 17;35(4):682-684. doi: 10.1002/joa3.12210. eCollection 2019 Aug.


Adiponectin levels among individuals with varied employment status in Japan: a cross-sectional analysis of the J-SHINE study.

Amano H, Shirakawa Y, Hashimoto H.

Sci Rep. 2019 Jul 29;9(1):10936. doi: 10.1038/s41598-019-47448-2.


Impact of stroke volume on severe aortic stenosis in patients with normal left ventricular function.

Fukui S, Kakizawa Y, Handa K, Sakamoto T, Shirakawa Y.

Gen Thorac Cardiovasc Surg. 2019 Jul 8. doi: 10.1007/s11748-019-01173-9. [Epub ahead of print]


Photoimmunotherapy for cancer-associated fibroblasts targeting fibroblast activation protein in human esophageal squamous cell carcinoma.

Watanabe S, Noma K, Ohara T, Kashima H, Sato H, Kato T, Urano S, Katsube R, Hashimoto Y, Tazawa H, Kagawa S, Shirakawa Y, Kobayashi H, Fujiwara T.

Cancer Biol Ther. 2019;20(9):1234-1248. doi: 10.1080/15384047.2019.1617566. Epub 2019 Jun 11.


Increased seizure sensitivity, emotional defects and cognitive impairment in PHD finger protein 24 (Phf24)-null rats.

Serikawa T, Kunisawa N, Shimizu S, Kato M, Alves Iha H, Kinboshi M, Nishikawa H, Shirakawa Y, Voigt B, Nakanishi S, Kuramoto T, Kaneko T, Yamamoto T, Mashimo T, Sasa M, Ohno Y.

Behav Brain Res. 2019 Sep 2;369:111922. doi: 10.1016/j.bbr.2019.111922. Epub 2019 Apr 27.


Change in tongue pressure and the related factors after esophagectomy: a short-term, longitudinal study.

Yokoi A, Ekuni D, Yamanaka R, Hata H, Shirakawa Y, Morita M.

Esophagus. 2019 Jul;16(3):300-308. doi: 10.1007/s10388-019-00668-x. Epub 2019 Apr 2.


Equations Estimating the Predissected Diameter of the Ascending Aorta for Acute Type A Aortic Dissection.

Yamauchi T, Takano H, Takahashi T, Masai T, Sakaki M, Shirakawa Y, Kitabayashi K, Asano N, Toda K, Sawa Y; Osaka Cardiovascular Surgery Research Group (OSCAR).

Ann Thorac Surg. 2019 Aug;108(2):481-490. doi: 10.1016/j.athoracsur.2019.02.046. Epub 2019 Mar 23.


Stable Iron Porphyrin Intramolecularly Coordinated by Alcoholate Anion: Synthesis and Evaluation of Axial Ligand Effect of Alcoholate on Spectroscopy and Catalytic Activity.

Shirakawa Y, Yano Y, Niwa Y, Inabe K, Umezawa N, Kato N, Hisamatsu Y, Higuchi T.

Inorg Chem. 2019 Apr 1;58(7):4268-4274. doi: 10.1021/acs.inorgchem.8b03384. Epub 2019 Mar 21.


Flap Reconstruction for Esophageal Perforation Following Anterior Cervical Plate Fixation.

Morita M, Matsumoto H, Shirakawa Y, Noma K, Tanabe S, Kimata Y.

Acta Med Okayama. 2019 Feb;73(1):77-80. doi: 10.18926/AMO/56462.


Burden of Implanted-Device-Detected Atrial High-Rate Episode Is Associated With Future Heart Failure Events - Clinical Significance of Asymptomatic Atrial Fibrillation in Patients With Implantable Cardiac Electronic Devices.

Nishinarita R, Niwano S, Fukaya H, Oikawa J, Nabeta T, Matsuura G, Arakawa Y, Kobayashi S, Shirakawa Y, Horiguchi A, Nakamura H, Ishizue N, Kishihara J, Satoh A, Ako J.

Circ J. 2019 Mar 25;83(4):736-742. doi: 10.1253/circj.CJ-18-1130. Epub 2019 Feb 26.


Hydrogen-Bonded Polyrotaxane Cation Structure in Nickel Dithiolate Anion Radical Salts: Ferromagnetic and Semiconducting Behavior Associated with Structural Phase Transition.

Shirakawa Y, Takahashi K, Sato H, Hoshino N, Anetai H, Noro SI, Akutagawa T, Nakamura T.

Chemistry. 2019 May 17;25(28):6920-6927. doi: 10.1002/chem.201806230. Epub 2019 Apr 17.


[Forefront of perioperative team medicine for esophageal cancer surgery].

Shirakawa Y, Tanabe S, Fujiwara T.

Nihon Shokakibyo Gakkai Zasshi. 2019;116(2):138-144. doi: 10.11405/nisshoshi.116.138. Japanese. No abstract available.


A Novel Combination Cancer Therapy with Iron Chelator Targeting Cancer Stem Cells via Suppressing Stemness.

Katsura Y, Ohara T, Noma K, Ninomiya T, Kashima H, Kato T, Sato H, Komoto S, Narusaka T, Tomono Y, Xing B, Chen Y, Tazawa H, Kagawa S, Shirakawa Y, Kasai T, Seno M, Matsukawa A, Fujiwara T.

Cancers (Basel). 2019 Feb 3;11(2). pii: E177. doi: 10.3390/cancers11020177.


Multicenter retrospective study to evaluate the efficacy and safety of the double-flap technique as antireflux esophagogastrostomy after proximal gastrectomy (rD-FLAP Study).

Kuroda S, Choda Y, Otsuka S, Ueyama S, Tanaka N, Muraoka A, Hato S, Kimura T, Tanakaya K, Kikuchi S, Tanabe S, Noma K, Nishizaki M, Kagawa S, Shirakawa Y, Kamikawa Y, Fujiwara T.

Ann Gastroenterol Surg. 2018 Oct 11;3(1):96-103. doi: 10.1002/ags3.12216. eCollection 2019 Jan.


Targeted exome sequencing of unselected heavy-ion beam-irradiated populations reveals less-biased mutation characteristics in the rice genome.

Ichida H, Morita R, Shirakawa Y, Hayashi Y, Abe T.

Plant J. 2019 Apr;98(2):301-314. doi: 10.1111/tpj.14213. Epub 2019 Feb 25.


Development of porous particles using dextran as an excipient for enhanced deep lung delivery of rifampicin.

Kadota K, Yanagawa Y, Tachikawa T, Deki Y, Uchiyama H, Shirakawa Y, Tozuka Y.

Int J Pharm. 2019 Jan 30;555:280-290. doi: 10.1016/j.ijpharm.2018.11.055. Epub 2018 Nov 22.


Cancer-associated fibroblasts (CAFs) promote the lymph node metastasis of esophageal squamous cell carcinoma.

Kashima H, Noma K, Ohara T, Kato T, Katsura Y, Komoto S, Sato H, Katsube R, Ninomiya T, Tazawa H, Shirakawa Y, Fujiwara T.

Int J Cancer. 2019 Feb 15;144(4):828-840. doi: 10.1002/ijc.31953. Epub 2018 Dec 3.


[The Elucidation of Tumor Immunosuppression Affected by Cancer-Associated Fibroblasts].

Kato T, Noma K, Katsura Y, Sato H, Kohmoto S, Ninomiya T, Ohara T, Tazawa H, Kagawa S, Shirakawa Y, Fujiwara T.

Gan To Kagaku Ryoho. 2018 Sep;45(9):1279-1281. Japanese.


New oral hygiene care regimen reduces postoperative oral bacteria count and number of days with elevated fever in ICU patients with esophageal cancer.

Mizuno H, Mizutani S, Ekuni D, Tabata-Taniguchi A, Maruyama T, Yokoi A, Omori C, Shimizu K, Morimatsu H, Shirakawa Y, Morita M.

J Oral Sci. 2018 Dec 27;60(4):536-543. doi: 10.2334/josnusd.17-0381. Epub 2018 Aug 30.


Clinical characteristics and management of gastric tube cancer after esophagectomy.

Shirakawa Y, Noma K, Maeda N, Ninomiya T, Tanabe S, Kikuchi S, Kuroda S, Nishizaki M, Kagawa S, Kawahara Y, Okada H, Fujiwara T.

Esophagus. 2018 Jul;15(3):180-189. doi: 10.1007/s10388-018-0611-2. Epub 2018 Mar 27.


Equations for Estimating the Predissected Diameter of the Descending Aorta From Computed Tomographic Images at the Onset of Aortic Dissection.

Yamauchi T, Masai T, Takano H, Shirakawa Y, Toda K, Sawa Y; Osaka Cardiovascular Surgery Research Group (OSCAR).

J Am Heart Assoc. 2018 Jun 26;7(13). pii: e009196. doi: 10.1161/JAHA.118.009196.


Cancer-Associated Fibroblasts Affect Intratumoral CD8+ and FoxP3+ T Cells Via IL6 in the Tumor Microenvironment.

Kato T, Noma K, Ohara T, Kashima H, Katsura Y, Sato H, Komoto S, Katsube R, Ninomiya T, Tazawa H, Shirakawa Y, Fujiwara T.

Clin Cancer Res. 2018 Oct 1;24(19):4820-4833. doi: 10.1158/1078-0432.CCR-18-0205. Epub 2018 Jun 19.


[Optimization of Scan Parameters for Patient without Breath Hold in Chest by Computed Tomography].

Takaku H, Sakamoto T, Shirakawa Y, Adachi T, Kayama H, Takahashi M, Ichikawa H.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018;74(2):133-139. doi: 10.6009/jjrt.2018_JSRT_74.2.133. Japanese.


[Radical Thoracoscopic Esophagectomy for Elderly Patients with Advanced Esophageal Cancer].

Matsumi Y, Shirakawa Y, Tanabe S, Komoto S, Maeda N, Ninomiya T, Noma K, Nishizaki M, Kagawa S, Fujiwara T.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1784-1786. Japanese.


[Successful Multimodality Treatment Including Three-Stage Operation for Esophageal Cancer with Esophagorespiratory Fistula - A Case Report].

Komoto S, Noma K, Maeda N, Matsumi Y, Ninomiya T, Tanabe S, Shirakawa Y, Fujiwara T.

Gan To Kagaku Ryoho. 2017 Nov;44(12):1053-1055. Review. Japanese.


A multi-institution phase II study of docetaxel and S-1 in combination with trastuzumab for HER2-positive advanced gastric cancer (DASH study).

Kagawa S, Muraoka A, Kambara T, Nakayama H, Hamano R, Tanaka N, Noma K, Tanakaya K, Kishimoto H, Shigeyasu K, Kuroda S, Kikuchi S, Kuwada K, Nishizaki M, Shirakawa Y, Fujiwara T.

Cancer Chemother Pharmacol. 2018 Feb;81(2):387-392. doi: 10.1007/s00280-017-3505-4. Epub 2017 Dec 30.


Iron depletion is a novel therapeutic strategy to target cancer stem cells.

Ninomiya T, Ohara T, Noma K, Katsura Y, Katsube R, Kashima H, Kato T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Chen L, Kasai T, Seno M, Matsukawa A, Fujiwara T.

Oncotarget. 2017 Oct 12;8(58):98405-98416. doi: 10.18632/oncotarget.21846. eCollection 2017 Nov 17.


Visualized Evaluation of Blood Flow to the Gastric Conduit and Complications in Esophageal Reconstruction.

Noma K, Shirakawa Y, Kanaya N, Okada T, Maeda N, Ninomiya T, Tanabe S, Sakurama K, Fujiwara T.

J Am Coll Surg. 2018 Mar;226(3):241-251. doi: 10.1016/j.jamcollsurg.2017.11.007. Epub 2017 Nov 22.


Hybrid Repair of an Abdominal Aortic Aneurysm: Debranching with Endovascular Aneurysm Repair in a Patient with Horseshoe Kidney.

Kin K, Takano H, Nakagawa T, Shirakawa Y.

Ann Vasc Dis. 2017 Mar 24;10(1):41-43. doi: 10.3400/ Epub 2017 Mar 31.


Diabetes mellitus adversely affects mortality and recurrence after valve surgery for infective endocarditis.

Yoshioka D, Toda K, Yokoyama JY, Matsuura R, Miyagawa S, Kainuma S, Sakaguchi T, Sakaki M, Nishi H, Shirakawa Y, Iwata K, Suhara H, Sakaniwa R, Fukuda H; Osaka Cardiovascular Research Group study group, Sawa Y.

J Thorac Cardiovasc Surg. 2018 Mar;155(3):1021-1029.e5. doi: 10.1016/j.jtcvs.2017.09.013. Epub 2017 Sep 15.


Primary synovial sarcoma of the left heart with large amount of necrotic tissue.

Maeda S, Takano H, Yamauchi T, Tanaka K, Suzuki K, Fushimi H, Shimazu K, Shirakawa Y.

Gen Thorac Cardiovasc Surg. 2018 Jun;66(6):365-367. doi: 10.1007/s11748-017-0828-3. Epub 2017 Sep 13.


Association between economic status and discharge destination among elderly patients from acute care hospitals.

Sakata N, Okumura Y, Shirakawa Y.

Nihon Koshu Eisei Zasshi. 2017;64(6):303-310. doi: 10.11236/jph.64.6_303. Japanese.


Recent Surgical Results for Active Endocarditis Complicated With Perivalvular Abscess.

Yoshioka D, Toda K, Yokoyama JY, Matsuura R, Miyagawa S, Shirakawa Y, Takahashi T, Sakaguchi T, Fukuda H, Sawa Y.

Circ J. 2017 Oct 25;81(11):1721-1729. doi: 10.1253/circj.CJ-17-0355. Epub 2017 Jun 8.


A case of long-term survival after surgical resection for solitary adrenal recurrence of esophageal squamous carcinoma.

Kanaya N, Noma K, Okada T, Maeda N, Tanabe S, Sakurama K, Shirakawa Y, Fujiwara T.

Surg Case Rep. 2017 Dec;3(1):61. doi: 10.1186/s40792-017-0337-8. Epub 2017 May 5.


Outcome of Radiation Monotherapy for High-risk Patients with Stage I Esophageal Cancer.

Shirakawa Y, Noma K, Maeda N, Tanabe S, Kuroda S, Kagawa S, Katsui K, Katayama N, Kanazawa S, Fujiwara T.

Acta Med Okayama. 2017 Apr;71(2):127-133. doi: 10.18926/AMO/54981.


Role of Thiolate Ligand in Spin State and Redox Switching in the Cytochrome P450 Catalytic Cycle.

Suzuki H, Inabe K, Shirakawa Y, Umezawa N, Kato N, Higuchi T.

Inorg Chem. 2017 Apr 17;56(8):4245-4248. doi: 10.1021/acs.inorgchem.6b02499. Epub 2017 Mar 28.



Shirakawa Y.

Nihon Geka Gakkai Zasshi. 2017 Mar;118(2):149-54. Japanese.


DEM Modelling of Granule Rearrangement and Fracture Behaviours During a Closed-Die Compaction.

Furukawa R, Kadota K, Noguchi T, Shimosaka A, Shirakawa Y.

AAPS PharmSciTech. 2017 Aug;18(6):2368-2377. doi: 10.1208/s12249-017-0719-z. Epub 2017 Jan 26.


Tumor-specific delivery of biologics by a novel T-cell line HOZOT.

Onishi T, Tazawa H, Hashimoto Y, Takeuchi M, Otani T, Nakamura S, Sakurai F, Mizuguchi H, Kishimoto H, Umeda Y, Shirakawa Y, Urata Y, Kagawa S, Fujiwara T.

Sci Rep. 2016 Nov 30;6:38060. doi: 10.1038/srep38060.


Effectiveness evaluation of Serigaya Methamphetamine Relapse Prevention Program in drug addiction rehabilitation center.

Kondo A, Kuritsubo C, Shirakawa Y, Matsumoto T.

Nihon Arukoru Yakubutsu Igakkai Zasshi. 2016 Dec;51(6):414-424. English, Japanese.


Heavy-ion beam mutagenesis identified an essential gene for chloroplast development under cold stress conditions during both early growth and tillering stages in rice.

Morita R, Nakagawa M, Takehisa H, Hayashi Y, Ichida H, Usuda S, Ichinose K, Abe H, Shirakawa Y, Sato T, Fujiwara MT, Itoh RD, Abe T.

Biosci Biotechnol Biochem. 2017 Feb;81(2):271-282. doi: 10.1080/09168451.2016.1249452. Epub 2016 Nov 2.


Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor.

Kikuchi S, Nishizaki M, Kuroda S, Tanabe S, Noma K, Kagawa S, Shirakawa Y, Kato H, Okada H, Fujiwara T.

Gastric Cancer. 2017 May;20(3):553-557. doi: 10.1007/s10120-016-0641-1. Epub 2016 Sep 6.


Severe tricuspid regurgitation after mitral valve surgery: the risk factors and results of the aggressive application of prophylactic tricuspid valve repair.

Takano H, Hiramatsu M, Kida H, Uenoyama M, Horiguchi K, Yamauchi T, Kin K, Shirakawa Y, Kaneko M, Daimon T.

Surg Today. 2017 Apr;47(4):445-456. doi: 10.1007/s00595-016-1395-4. Epub 2016 Aug 8.


Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer.

Nishitani S, Noma K, Ohara T, Tomono Y, Watanabe S, Tazawa H, Shirakawa Y, Fujiwara T.

Int J Oncol. 2016 Oct;49(4):1351-9. doi: 10.3892/ijo.2016.3640. Epub 2016 Jul 29.


Trimodality Therapy for an Advanced Thymic Carcinoma With Both Aorta and Vena Cava Invasion.

Momozane T, Inoue M, Shintani Y, Funaki S, Kawamura T, Minami M, Shirakawa Y, Kuratani T, Sawa Y, Okumura M.

Ann Thorac Surg. 2016 Aug;102(2):e139-41. doi: 10.1016/j.athoracsur.2016.01.014.


Recurrence after Endoscopic Curative Resection of Mucosal Gastric Cancer Associated with an Adjacent Neoplastic Precursor Lesion.

Kikuchi S, Kagawa S, Ohara T, Kubota T, Kuwada K, Kagawa T, Kuroda S, Shirakawa Y, Nishizaki M, Fujiwara T.

Acta Med Okayama. 2016 Jun;70(3):213-216.


Genetic polymorphism at codon 546 of the human RAD17 contributes to the risk for esophageal squamous cell carcinoma.

Yasuda Y, Sakai A, Ito S, Mita Y, Sonoyama T, Tanabe S, Shirakawa Y, Naomoto Y, Katayama H, Shimizu K.

Int J Mol Epidemiol Genet. 2016 Mar 23;7(1):58-66. eCollection 2016.


Double-Flap Technique as an Antireflux Procedure in Esophagogastrostomy after Proximal Gastrectomy.

Kuroda S, Nishizaki M, Kikuchi S, Noma K, Tanabe S, Kagawa S, Shirakawa Y, Fujiwara T.

J Am Coll Surg. 2016 Aug;223(2):e7-e13. doi: 10.1016/j.jamcollsurg.2016.04.041. Epub 2016 May 6. No abstract available.


Iron depletion enhances the effect of sorafenib in hepatocarcinoma.

Urano S, Ohara T, Noma K, Katsube R, Ninomiya T, Tomono Y, Tazawa H, Kagawa S, Shirakawa Y, Kimura F, Nouso K, Matsukawa A, Yamamoto K, Fujiwara T.

Cancer Biol Ther. 2016 Jun 2;17(6):648-56. doi: 10.1080/15384047.2016.1177677. Epub 2016 Apr 18.

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