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Items: 1 to 50 of 406

1.

Dual-FRET imaging of IP3 and Ca2+ revealed Ca2+-induced IP3 production maintains long lasting Ca2+ oscillations in fertilized mouse eggs.

Matsu-Ura T, Shirakawa H, Suzuki KGN, Miyamoto A, Sugiura K, Michikawa T, Kusumi A, Mikoshiba K.

Sci Rep. 2019 Mar 18;9(1):4829. doi: 10.1038/s41598-019-40931-w.

2.

An Adenosine A2A Receptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis.

Asaoka N, Nishitani N, Kinoshita H, Nagai Y, Hatakama H, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

eNeuro. 2019 Feb 27;6(1). pii: ENEURO.0366-18.2019. doi: 10.1523/ENEURO.0366-18.2019. eCollection 2019 Jan-Feb.

3.

Rat-derived feeder cells immortalized by expression of mutant CDK4, cyclin D, and telomerase can support stem cell growth.

Katayama M, Kiyono T, Kuroda K, Ueda K, Onuma M, Shirakawa H, Fukuda T.

Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):945-956. doi: 10.1016/j.bbamcr.2019.02.013. Epub 2019 Mar 1.

PMID:
30826331
4.

Adenosine and adenosine-5'-monophosphate ingestion ameliorates abnormal glucose metabolism in mice fed a high-fat diet.

Ardiansyah, Inagawa Y, Koseki T, Agista AZ, Ikeda I, Goto T, Komai M, Shirakawa H.

BMC Complement Altern Med. 2018 Nov 14;18(1):304. doi: 10.1186/s12906-018-2367-6.

5.

Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats.

Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Andoh C, Nagai Y, Kinoshita H, Kawai H, Shibui N, Liu B, Hewinson J, Shirakawa H, Nakagawa T, Hashimoto H, Kasparov S, Kaneko S.

Neuropsychopharmacology. 2019 Mar;44(4):721-732. doi: 10.1038/s41386-018-0254-y. Epub 2018 Oct 30.

PMID:
30377380
6.

Once-daily vs twice-daily tacrolimus for de novo living kidney transplantation patients including ABO/HLA compatible and incompatible: A randomized trial.

Okumi M, Unagami K, Furusawa M, Kakuta Y, IIzuka J, Takagi T, Shirakawa H, Shimizu T, Omoto K, Inui M, Ishida H, Tanabe K.

Clin Transplant. 2018 Dec;32(12):e13423. doi: 10.1111/ctr.13423. Epub 2018 Nov 8.

PMID:
30318624
7.

Recurrent Membranous Nephropathy After Kidney Transplantation Associated With Phospholipase A2 Receptor and Successfully Treated With Rituximab: A Case Report.

Ishiwatari A, Wakai S, Shirakawa H, Honda K.

Transplant Proc. 2018 Oct;50(8):2565-2568. doi: 10.1016/j.transproceed.2018.03.083. Epub 2018 Mar 19.

PMID:
30316399
8.

TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility.

Andoh C, Nishitani N, Hashimoto E, Nagai Y, Takao K, Miyakawa T, Nakagawa T, Mori Y, Nagayasu K, Shirakawa H, Kaneko S.

Brain Res. 2019 Feb 1;1704:68-77. doi: 10.1016/j.brainres.2018.09.031. Epub 2018 Sep 28.

PMID:
30273551
9.

Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models.

Takeda TA, Miyazaki S, Kobayashi M, Nishino K, Goto T, Matsunaga M, Ooi M, Shirakawa H, Tani F, Kawamura T, Komai M, Kambe T.

Commun Biol. 2018 Aug 22;1:113. doi: 10.1038/s42003-018-0118-3. eCollection 2018.

10.

Orexigenic action of oral zinc: metabolomic analysis in the rat hypothalamus.

Nishiuchi M, Sakai K, Tajima H, Katayama K, Kimura F, Hoshi S, Goto T, Shirakawa H, Komai M.

Biosci Biotechnol Biochem. 2018 Dec;82(12):2168-2175. doi: 10.1080/09168451.2018.1516543. Epub 2018 Sep 21.

PMID:
30240332
11.

TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.

Tsutsui M, Hirase R, Miyamura S, Nagayasu K, Nakagawa T, Mori Y, Shirakawa H, Kaneko S.

J Neurosci. 2018 Sep 26;38(39):8484-8495. doi: 10.1523/JNEUROSCI.2203-17.2018. Epub 2018 Sep 10.

PMID:
30201769
12.

The impact of mouse strain-specific spatial and temporal immune responses on the progression of neuropathic pain.

Isami K, Imai S, Sukeishi A, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Brain Behav Immun. 2018 Nov;74:121-132. doi: 10.1016/j.bbi.2018.08.013. Epub 2018 Aug 29.

PMID:
30171890
13.

A Case of a Pneumocystis Pneumonia Twenty-four Years After Living Kidney Transplantation Due to Withdrawal of Sulfamethoxazole/Trimethoprim Prophylaxis.

Kono M, Kojima K, Wakai S, Shirakawa H.

Transplant Direct. 2018 May 22;4(6):e359. doi: 10.1097/TXD.0000000000000796. eCollection 2018 Jun. No abstract available.

14.

Development of novel silanol-based human pregnane X receptor (PXR) agonists with improved receptor selectivity.

Toyama H, Shirakawa H, Komai M, Hashimoto Y, Fujii S.

Bioorg Med Chem. 2018 Aug 15;26(15):4493-4501. doi: 10.1016/j.bmc.2018.07.038. Epub 2018 Jul 24.

PMID:
30077610
15.

Physiological and Pathophysiological Roles of Transient Receptor Potential Channels in Microglia-Related CNS Inflammatory Diseases.

Shirakawa H, Kaneko S.

Biol Pharm Bull. 2018;41(8):1152-1157. doi: 10.1248/bpb.b18-00319. Review.

16.

[Clarification of the Mechanism Involved in Orexigenic Action by Oral Zinc Ingestion].

Komai M, Goto T, Ohinata K, Kambe T, Mayanagi Y, Shirakawa H.

Yakugaku Zasshi. 2018;138(8):1011-1016. doi: 10.1248/yakushi.17-00048-2. Review. Japanese.

17.

Effects of Vitamin K₂ on the Expression of Genes Involved in Bile Acid Synthesis and Glucose Homeostasis in Mice with Humanized PXR.

Sultana H, Watanabe K, Rana MM, Takashima R, Ohashi A, Komai M, Shirakawa H.

Nutrients. 2018 Jul 27;10(8). pii: E982. doi: 10.3390/nu10080982.

18.

TRPA1 sensitization during diabetic vascular impairment contributes to cold hypersensitivity in a mouse model of painful diabetic peripheral neuropathy.

Hiyama H, Yano Y, So K, Imai S, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Mol Pain. 2018 Jan-Dec;14:1744806918789812. doi: 10.1177/1744806918789812. Epub 2018 Jul 3.

19.

Neurotropin inhibits neuronal activity through potentiation of sustained Kv currents in primary cultured DRG neurons.

Kawai H, Asaoka N, Miyake T, Nagayasu K, Nakagawa T, Shirakawa H, Kaneko S.

J Pharmacol Sci. 2018 Jul;137(3):313-316. doi: 10.1016/j.jphs.2018.05.005. Epub 2018 May 31.

20.

Rapid progression of a granulocyte colony-stimulating factor-producing liver tumor metastasized from esophagogastric junction cancer: A case report and literature review.

Hoshimoto S, Hoshi N, Ozawa I, Tomikawa M, Shirakawa H, Fujita T, Wakamatsu S, Hoshi S, Hirabayashi K, Hishinuma S, Ogata Y.

Oncol Lett. 2018 May;15(5):6475-6480. doi: 10.3892/ol.2018.8144. Epub 2018 Mar 1.

21.

TRPV4 is functionally expressed in oligodendrocyte precursor cells and increases their proliferation.

Ohashi K, Deyashiki A, Miyake T, Nagayasu K, Shibasaki K, Shirakawa H, Kaneko S.

Pflugers Arch. 2018 May;470(5):705-716. doi: 10.1007/s00424-018-2130-3. Epub 2018 Mar 22.

PMID:
29569183
22.

TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion.

Miyanohara J, Kakae M, Nagayasu K, Nakagawa T, Mori Y, Arai K, Shirakawa H, Kaneko S.

J Neurosci. 2018 Apr 4;38(14):3520-3533. doi: 10.1523/JNEUROSCI.2451-17.2018. Epub 2018 Mar 9.

23.

Investigation of the key determinants of Asian nurses' quality of life.

Makabe S, Kowitlawakul Y, Nurumal MS, Takagai J, Wichaikhum OA, Wangmo N, Yap SF, Kunaviktikul W, Komatsu J, Shirakawa H, Kimura Y, Asanuma Y.

Ind Health. 2018 Jun 1;56(3):212-219. doi: 10.2486/indhealth.2017-0066. Epub 2018 Feb 28.

24.

Ketamine-Induced Prefrontal Serotonin Release Is Mediated by Cholinergic Neurons in the Pedunculopontine Tegmental Nucleus.

Kinoshita H, Nishitani N, Nagai Y, Andoh C, Asaoka N, Kawai H, Shibui N, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Int J Neuropsychopharmacol. 2018 Mar 1;21(3):305-310. doi: 10.1093/ijnp/pyy007.

25.

TRP Channels in the Brain: What Are They There For?.

Sawamura S, Shirakawa H, Nakagawa T, Mori Y, Kaneko S.

In: Emir TLR, editor. Neurobiology of TRP Channels. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2017. Chapter 16.

26.

Clinical and Pathological Features of Plasma Cell-Rich Acute Rejection After Kidney Transplantation.

Hasegawa J, Honda K, Omoto K, Wakai S, Shirakawa H, Okumi M, Ishida H, Fuchinoue S, Hattori M, Tanabe K.

Transplantation. 2018 May;102(5):853-859. doi: 10.1097/TP.0000000000002041.

PMID:
29319615
27.

A novel function of geranylgeraniol in regulating testosterone production.

Ho HJ, Shirakawa H, Giriwono PE, Ito A, Komai M.

Biosci Biotechnol Biochem. 2018 Jun;82(6):956-962. doi: 10.1080/09168451.2017.1415129. Epub 2018 Jan 5. Review.

PMID:
29303051
28.

False Elevation of the Blood Tacrolimus Concentration, as Assessed by an Affinity Column-mediated Immunoassay (ACMIA), Led to Acute T Cell-mediated Rejection after Kidney Transplantation.

Kono M, Hasegawa J, Ogawa H, Yoshikawa K, Ishiwatari A, Wakai S, Tanabe K, Shirakawa H.

Intern Med. 2018 May 1;57(9):1265-1268. doi: 10.2169/internalmedicine.0071-17. Epub 2017 Dec 27.

29.

Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide.

Oyama S, Dogishi K, Kodera M, Kakae M, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Front Physiol. 2017 Nov 7;8:877. doi: 10.3389/fphys.2017.00877. eCollection 2017.

30.

Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin.

Miyake T, Nakamura S, Meng Z, Hamano S, Inoue K, Numata T, Takahashi N, Nagayasu K, Shirakawa H, Mori Y, Nakagawa T, Kaneko S.

Front Physiol. 2017 Nov 1;8:878. doi: 10.3389/fphys.2017.00878. eCollection 2017.

31.

Colchicine alleviates acute postoperative pain but delays wound repair in mice: roles of neutrophils and macrophages.

Sukeishi A, Isami K, Hiyama H, Imai S, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Mol Pain. 2017 Jan-Dec;13:1744806917743680. doi: 10.1177/1744806917743680.

32.

Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABAB receptor-mediated inhibition of L-type calcium channels.

Asaoka N, Nishitani N, Kinoshita H, Kawai H, Shibui N, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.

Sci Rep. 2017 Oct 19;7(1):13609. doi: 10.1038/s41598-017-13599-3.

33.

Preemptive anti-cytomegalovirus therapy in high-risk (donor-positive, recipient-negative cytomegalovirus serostatus) kidney transplant recipients.

Hasegawa J, Hatakeyama S, Wakai S, Omoto K, Okumi M, Tanabe K, Mieno M, Shirakawa H.

Int J Infect Dis. 2017 Dec;65:50-56. doi: 10.1016/j.ijid.2017.09.023. Epub 2017 Oct 3.

34.

Clinical implications of the proliferative ability of the squamous component regarding tumor progression of adenosquamous carcinoma of the pancreas: A preliminary report.

Hoshimoto S, Hoshi N, Hishinuma S, Shirakawa H, Tomikawa M, Ozawa I, Wakamatsu S, Hoshi S, Hirabayashi K, Ogata Y.

Pancreatology. 2017 Sep - Oct;17(5):788-794. doi: 10.1016/j.pan.2017.08.001. Epub 2017 Aug 2.

PMID:
28784574
35.

Dietary Supplementation of Fermented Rice Bran Effectively Alleviates Dextran Sodium Sulfate-Induced Colitis in Mice.

Islam J, Koseki T, Watanabe K; Ardiansyah, Budijanto S, Oikawa A, Alauddin M, Goto T, Aso H, Komai M, Shirakawa H.

Nutrients. 2017 Jul 13;9(7). pii: E747. doi: 10.3390/nu9070747.

36.

Living Kidney Donation From a Donor With Pulmonary Sarcoidosis: A Case Report and Review of the Literature.

Kono M, Hasegawa J, Wakai S, Ishiwatari A, Abe Y, Endo M, Sakoma T, Miyake K, Tokumoto T, Tanabe K, Shirakawa H.

Transplant Proc. 2017 Jun;49(5):1183-1186. doi: 10.1016/j.transproceed.2017.03.025. Review.

PMID:
28583552
37.

Genotyping Analysis of Bitter-Taste Receptor Genes TAS2R38 and TAS2R46 in Japanese Patients with Gastrointestinal Cancers.

Yamaki M, Saito H, Isono K, Goto T, Shirakawa H, Shoji N, Satoh-Kuriwada S, Sasano T, Okada R, Kudoh K, Motoi F, Unno M, Komai M.

J Nutr Sci Vitaminol (Tokyo). 2017;63(2):148-154. doi: 10.3177/jnsv.63.148.

38.

Reassessment of the clinical significance of portal-superior mesenteric vein invasion in borderline resectable pancreatic cancer.

Hoshimoto S, Hishinuma S, Shirakawa H, Tomikawa M, Ozawa I, Wakamatsu S, Hoshi S, Hoshi N, Hirabayashi K, Ogata Y.

Eur J Surg Oncol. 2017 Jun;43(6):1068-1075. doi: 10.1016/j.ejso.2017.03.020. Epub 2017 Apr 8.

PMID:
28427822
39.

Temperature Dependence in the Terahertz Spectrum of Nicotinamide: Anharmonicity and Hydrogen-Bonded Network.

Takahashi M, Okamura N, Fan X, Shirakawa H, Minamide H.

J Phys Chem A. 2017 Apr 6;121(13):2558-2564. doi: 10.1021/acs.jpca.6b11049. Epub 2017 Mar 28.

PMID:
28319387
40.

Sphingosine-1-phosphate induces Ca2+ signaling and CXCL1 release via TRPC6 channel in astrocytes.

Shirakawa H, Katsumoto R, Iida S, Miyake T, Higuchi T, Nagashima T, Nagayasu K, Nakagawa T, Kaneko S.

Glia. 2017 Jun;65(6):1005-1016. doi: 10.1002/glia.23141. Epub 2017 Mar 16.

PMID:
28300348
41.

In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers.

Wakizaka M, Eshima H, Tanaka Y, Shirakawa H, Poole DC, Kano Y.

Physiol Rep. 2017 Mar;5(5). pii: e13180. doi: 10.14814/phy2.13180.

42.

A rat long-lasting cystitis model induced by intravesical injection of hydrogen peroxide.

Dogishi K, Okamoto K, Majima T, Konishi-Shiotsu S, Homan T, Kodera M, Oyama S, Oyama T, Shirakawa H, Yoshimura N, Nakagawa T, Kaneko S.

Physiol Rep. 2017 Feb;5(4). pii: e13127. doi: 10.14814/phy2.13127. Epub 2017 Feb 27.

43.

Sequential PET estimation of cerebral oxygen metabolism with spontaneous respiration of 15O-gas in mice with bilateral common carotid artery stenosis.

Temma T, Yamazaki M, Miyanohara J, Shirakawa H, Kondo N, Koshino K, Kaneko S, Iida H.

J Cereb Blood Flow Metab. 2017 Oct;37(10):3334-3343. doi: 10.1177/0271678X17692815. Epub 2017 Feb 9.

44.

Dietary tryptophan alleviates dextran sodium sulfate-induced colitis through aryl hydrocarbon receptor in mice.

Islam J, Sato S, Watanabe K, Watanabe T, Ardiansyah, Hirahara K, Aoyama Y, Tomita S, Aso H, Komai M, Shirakawa H.

J Nutr Biochem. 2017 Apr;42:43-50. doi: 10.1016/j.jnutbio.2016.12.019. Epub 2017 Jan 12.

PMID:
28113104
45.

Perioperative plasma glypican-3 level may enable prediction of the risk of recurrence after surgery in patients with stage I hepatocellular carcinoma.

Ofuji K, Saito K, Suzuki S, Shimomura M, Shirakawa H, Nobuoka D, Sawada Y, Yoshimura M, Tsuchiya N, Takahashi M, Yoshikawa T, Tada Y, Konishi M, Takahashi S, Gotohda N, Nakamoto Y, Nakatsura T.

Oncotarget. 2017 Jun 6;8(23):37835-37844. doi: 10.18632/oncotarget.14271.

46.

Adenosquamous carcinoma in the biliary tract: association of the proliferative ability of the squamous component with its proportion and tumor progression.

Hoshimoto S, Hoshi S, Hishinuma S, Tomikawa M, Shirakawa H, Ozawa I, Wakamatsu S, Hoshi N, Hirabayashi K, Ogata Y.

Scand J Gastroenterol. 2017 Apr;52(4):425-430. doi: 10.1080/00365521.2016.1273383. Epub 2016 Dec 30.

PMID:
28034323
47.

A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons.

Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S.

J Toxicol Sci. 2016;41(6):813-816.

48.

Prognostic significance of intraoperative peritoneal washing cytology for patients with potentially resectable pancreatic ductal adenocarcinoma.

Hoshimoto S, Hishinuma S, Shirakawa H, Tomikawa M, Ozawa I, Hoshi N, Hoshi S, Hirabayashi K, Ogata Y.

Pancreatology. 2017 Jan - Feb;17(1):109-114. doi: 10.1016/j.pan.2016.11.001. Epub 2016 Nov 7.

PMID:
27840175
49.

Fermented rice bran supplementation mitigates metabolic syndrome in stroke-prone spontaneously hypertensive rats.

Alauddin M, Shirakawa H, Koseki T, Kijima N, Ardiansyah, Budijanto S, Islam J, Goto T, Komai M.

BMC Complement Altern Med. 2016 Nov 8;16(1):442.

50.

Competent Route to Unsymmetric Dimer Architectures: Total Syntheses of (-)-Lycodine and (-)-Complanadines A and B, and Evaluation of Their Neurite Outgrowth Activities.

Zhao L, Tsukano C, Kwon E, Shirakawa H, Kaneko S, Takemoto Y, Hirama M.

Chemistry. 2017 Jan 18;23(4):802-812. doi: 10.1002/chem.201604647. Epub 2016 Nov 25.

PMID:
27758009

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