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Items: 1 to 50 of 84

1.

Iterative Arylation of Itaconimides with Diazonium Salts through Electrophilic Palladium Catalysis: Divergent β-H-Elimination Pathways in Repetitive Matsuda-Heck Reactions.

Riemer N, Shipman M, Wessig P, Schmidt B.

J Org Chem. 2019 May 3;84(9):5732-5746. doi: 10.1021/acs.joc.9b00627. Epub 2019 Apr 23.

PMID:
30990318
2.

Macrocyclisation of small peptides enabled by oxetane incorporation.

Roesner S, Saunders GJ, Wilkening I, Jayawant E, Geden JV, Kerby P, Dixon AM, Notman R, Shipman M.

Chem Sci. 2019 Jan 3;10(8):2465-2472. doi: 10.1039/c8sc05474f. eCollection 2019 Feb 28.

3.

Cerebellum and cognition: Does the rodent cerebellum participate in cognitive functions?

Shipman ML, Green JT.

Neurobiol Learn Mem. 2019 Feb 13. pii: S1074-7427(19)30027-9. doi: 10.1016/j.nlm.2019.02.006. [Epub ahead of print]

PMID:
30771461
4.

A statistical description of scattering at the quantum level.

Laricchia G, Van Reeth P, Fayer SE, Brawley SJ, Kadokura R, Loreti A, Shipman M.

Sci Rep. 2018 Oct 10;8(1):15056. doi: 10.1038/s41598-018-33425-8.

5.

Inactivation of prelimbic and infralimbic cortex respectively affects minimally-trained and extensively-trained goal-directed actions.

Shipman ML, Trask S, Bouton ME, Green JT.

Neurobiol Learn Mem. 2018 Nov;155:164-172. doi: 10.1016/j.nlm.2018.07.010. Epub 2018 Jul 24.

PMID:
30053577
6.

Phyllostictine A: total synthesis, structural verification and determination of substructure responsible for plant growth inhibition.

Riemer M, Uzunova VV, Riemer N, Clarkson GJ, Pereira N, Napier R, Shipman M.

Chem Commun (Camb). 2018 Jun 26;54(52):7211-7214. doi: 10.1039/c8cc03349h.

7.

Enzymatically-stable oxetane-based dipeptide hydrogels.

McDougall L, Draper ER, Beadle JD, Shipman M, Raubo P, Jamieson AG, Adams DJ.

Chem Commun (Camb). 2018 Feb 13;54(14):1793-1796. doi: 10.1039/c7cc09701h.

PMID:
29384155
8.

Synthesis of 4,5-Diazaspiro[2.3]hexanes and 1,2-Diazaspiro[3.3]heptanes as Hexahydropyridazine Analogues.

Pancholi AK, Iacobini GP, Clarkson GJ, Porter DW, Shipman M.

J Org Chem. 2018 Jan 5;83(1):491-498. doi: 10.1021/acs.joc.7b02622. Epub 2017 Dec 11.

PMID:
29183129
9.

Solid-Phase Synthesis of Oxetane Modified Peptides.

Beadle JD, Knuhtsen A, Hoose A, Raubo P, Jamieson AG, Shipman M.

Org Lett. 2017 Jun 16;19(12):3303-3306. doi: 10.1021/acs.orglett.7b01466. Epub 2017 Jun 6.

PMID:
28585839
10.

Testicular torsion: A retrospective investigation of predictors of surgical outcomes and of remaining controversies.

Castañeda-Sánchez I, Tully B, Shipman M, Hoeft A, Hamby T, Palmer BW.

J Pediatr Urol. 2017 Oct;13(5):516.e1-516.e4. doi: 10.1016/j.jpurol.2017.03.030. Epub 2017 Apr 21.

PMID:
28476481
11.

Regio- and Stereocontrolled Synthesis of 3-Substituted 1,2-Diazetidines by Asymmetric Allylic Amination of Vinyl Epoxide.

Rajkumar S, Clarkson GJ, Shipman M.

Org Lett. 2017 Apr 21;19(8):2058-2061. doi: 10.1021/acs.orglett.7b00653. Epub 2017 Apr 4.

PMID:
28375013
12.

Inactivation of the Prelimbic Cortex Attenuates Context-Dependent Operant Responding.

Trask S, Shipman ML, Green JT, Bouton ME.

J Neurosci. 2017 Mar 1;37(9):2317-2324. doi: 10.1523/JNEUROSCI.3361-16.2017. Epub 2017 Jan 30.

13.

Functional Genomic Analyses of Mendelian and Sporadic Disease Identify Impaired eIF2α Signaling as a Generalizable Mechanism for Dystonia.

Rittiner JE, Caffall ZF, Hernández-Martinez R, Sanderson SM, Pearson JL, Tsukayama KK, Liu AY, Xiao C, Tracy S, Shipman MK, Hickey P, Johnson J, Scott B, Stacy M, Saunders-Pullman R, Bressman S, Simonyan K, Sharma N, Ozelius LJ, Cirulli ET, Calakos N.

Neuron. 2016 Dec 21;92(6):1238-1251. doi: 10.1016/j.neuron.2016.11.012. Epub 2016 Dec 8.

14.

Functionalization of Alkenes through Telescoped Continuous Flow Aziridination Processes.

Hsueh N, Clarkson GJ, Shipman M.

Org Lett. 2016 Oct 7;18(19):4908-4911. Epub 2016 Sep 13.

PMID:
27622836
15.

Asymmetric Synthesis of 2-Substituted Azetidin-3-ones via Metalated SAMP/RAMP Hydrazones.

Pancholi AK, Geden JV, Clarkson GJ, Shipman M.

J Org Chem. 2016 Sep 2;81(17):7984-92. doi: 10.1021/acs.joc.6b01284. Epub 2016 Aug 9.

PMID:
27447363
16.

Integrated molecular, physiological and in silico characterization of two Halomonas isolates from industrial brine.

Carlson RP, Oshota O, Shipman M, Caserta JA, Hu P, Saunders CW, Xu J, Jay ZJ, Reeder N, Richards A, Pettigrew C, Peyton BM.

Extremophiles. 2016 May;20(3):261-74. doi: 10.1007/s00792-015-0806-6. Epub 2016 Feb 18.

PMID:
26888357
17.

Positronium Production and Scattering below Its Breakup Threshold.

Brawley SJ, Fayer SE, Shipman M, Laricchia G.

Phys Rev Lett. 2015 Nov 27;115(22):223201. Epub 2015 Nov 24.

PMID:
26650302
18.

Absolute Differential Positronium-Formation Cross Sections.

Shipman M, Armitage S, Beale J, Brawley SJ, Fayer SE, Garner AJ, Leslie DE, Van Reeth P, Laricchia G.

Phys Rev Lett. 2015 Jul 17;115(3):033401. Epub 2015 Jul 14.

PMID:
26230792
19.

Generation and Ring Opening of Aziridines in Telescoped Continuous Flow Processes.

Hsueh N, Clarkson GJ, Shipman M.

Org Lett. 2015 Jul 17;17(14):3632-5. doi: 10.1021/acs.orglett.5b01777. Epub 2015 Jul 9.

PMID:
26158313
20.

Ring closing metathesis reactions of α-methylene-β-lactams: application to the synthesis of a simplified phyllostictine analogue with herbicidal activity.

Coe S, Pereira N, Geden JV, Clarkson GJ, Fox DJ, Napier RM, Neve P, Shipman M.

Org Biomol Chem. 2015 Jul 28;13(28):7655-63. doi: 10.1039/c5ob00890e.

PMID:
26081012
21.

Nitrogen Stereodynamics and Complexation Phenomena as Key Factors in the Deprotonative Dynamic Resolution of Alkylideneaziridines: A Spectroscopic and Computational Study.

Degennaro L, Pisano L, Parisi G, Mansueto R, Clarkson GJ, Shipman M, Luisi R.

J Org Chem. 2015 Jun 19;80(12):6411-8. doi: 10.1021/acs.joc.5b00848. Epub 2015 Jun 2.

PMID:
25996163
22.

Targeting the nicotinic cholinergic system to treat attention-deficit/hyperactivity disorder: rationale and progress to date.

Potter AS, Schaubhut G, Shipman M.

CNS Drugs. 2014 Dec;28(12):1103-13. doi: 10.1007/s40263-014-0208-9. Review.

23.

Stereocontrolled lithiation/trapping of chiral 2-alkylideneaziridines: investigation into the role of the aziridine nitrogen stereodynamics.

Mansueto R, Degennaro L, Brière JF, Griffin K, Shipman M, Florio S, Luisi R.

Org Biomol Chem. 2014 Nov 14;12(42):8505-11. doi: 10.1039/c4ob01457j. Erratum in: Org Biomol Chem. 2014 Nov 28;12(44):9028.

PMID:
25232795
24.

Synthesis and structure of oxetane containing tripeptide motifs.

Powell NH, Clarkson GJ, Notman R, Raubo P, Martin NG, Shipman M.

Chem Commun (Camb). 2014 Aug 14;50(63):8797-800. doi: 10.1039/c4cc03507k. Epub 2014 Jun 26.

PMID:
24968282
25.

Selective hippocampal lesions impair acquisition of appetitive trace conditioning with long intertrial and long trace intervals.

Chan K, Shipman ML, Kister E.

Behav Neurosci. 2014 Feb;128(1):92-102. doi: 10.1037/a0035606.

PMID:
24512069
26.

A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis.

Winawer MR, Klassen TL, Teed S, Shipman M, Leung EH, Palmer AA.

Genes Brain Behav. 2014 Mar;13(3):341-9. doi: 10.1111/gbb.12116. Epub 2014 Jan 27.

27.

Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones.

Geden JV, Beasley BO, Clarkson GJ, Shipman M.

J Org Chem. 2013 Dec 6;78(23):12243-50. doi: 10.1021/jo4020485. Epub 2013 Nov 11.

28.

Proteomic and systems biology analysis of the monocyte response to Coxiella burnetii infection.

Shipman M, Lubick K, Fouchard D, Gurram R, Grieco P, Jutila M, Dratz EA.

PLoS One. 2013 Aug 21;8(8):e69558. doi: 10.1371/journal.pone.0069558. eCollection 2013.

29.

Photochemical control of molecular motion associated with pyramidal inversion.

Hough AJ, Prokes I, Tucker JH, Shipman M, Walsh TR.

Chem Commun (Camb). 2013 Jul 28;49(59):6683-5. doi: 10.1039/c3cc43036g.

PMID:
23774964
30.

Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines.

Geden JV, Pancholi AK, Shipman M.

J Org Chem. 2013 Apr 19;78(8):4158-64. doi: 10.1021/jo400252n. Epub 2013 Mar 21.

31.

Study of boron-nitrogen dative bonds using azetidine inversion dynamics.

Hoang CT, Prokes I, Clarkson GJ, Rowland MJ, Tucker JH, Shipman M, Walsh TR.

Chem Commun (Camb). 2013 Mar 28;49(25):2509-11. doi: 10.1039/c3cc36159d.

PMID:
23423181
32.

Increased hyphal branching and growth of ectomycorrhizal fungus Lactarius rufus by the helper bacterium Paenibacillus sp.

Aspray TJ, Jones EE, Davies MW, Shipman M, Bending GD.

Mycorrhiza. 2013 Jul;23(5):403-10. doi: 10.1007/s00572-013-0483-1. Epub 2013 Feb 9.

PMID:
23397165
33.

Proteomic and systems biology analysis of monocytes exposed to securinine, a GABA(A) receptor antagonist and immune adjuvant.

Shipman M, Lubick K, Fouchard D, Guram R, Grieco P, Jutila M, Dratz EA.

PLoS One. 2012;7(9):e41278. doi: 10.1371/journal.pone.0041278. Epub 2012 Sep 13.

34.

Chemo- and enantioselective Rh-catalysed hydrogenation of 3-methylene-1,2-diazetidines: application to vicinal diamine synthesis.

Iacobini GP, Porter DW, Shipman M.

Chem Commun (Camb). 2012 Oct 11;48(79):9852-4. doi: 10.1039/c2cc35445d. Epub 2012 Aug 29.

PMID:
22932718
35.

Lewis acid promoted intramolecular (3 + 2) 'cycloadditions' of methyleneaziridines with alkene and alkyne acceptors.

Griffin K, Montagne C, Hoang CT, Clarkson GJ, Shipman M.

Org Biomol Chem. 2012 Feb 7;10(5):1032-9. doi: 10.1039/c1ob06578e. Epub 2011 Dec 7.

PMID:
22159193
36.

Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis.

Brown MJ, Clarkson GJ, Inglis GG, Shipman M.

Org Lett. 2011 Apr 1;13(7):1686-9. doi: 10.1021/ol200193n. Epub 2011 Mar 2.

PMID:
21366285
37.

Tetrahydroxanthones by sequential Pd-catalyzed C-O and C-C bond construction and use in the identification of the "antiausterity" pharmacophore of the kigamicins.

Turner PA, Griffin EM, Whatmore JL, Shipman M.

Org Lett. 2011 Mar 4;13(5):1056-9. doi: 10.1021/ol103103n. Epub 2011 Jan 26.

PMID:
21268595
38.

Resonant scattering of positronium in collision with CO2.

Brawley SJ, Williams AI, Shipman M, Laricchia G.

Phys Rev Lett. 2010 Dec 31;105(26):263401. Epub 2010 Dec 22.

PMID:
21231658
39.

Aziridine scaffolds for the detection and quantification of hydrogen-bonding interactions through transition-state stabilization.

Giordano L, Hoang CT, Shipman M, Tucker JH, Walsh TR.

Angew Chem Int Ed Engl. 2011 Jan 17;50(3):741-4. doi: 10.1002/anie.201005580. Epub 2010 Dec 22. No abstract available.

PMID:
21226167
40.

Rac activation by the T-cell receptor inhibits T cell migration.

Cernuda-Morollón E, Millán J, Shipman M, Marelli-Berg FM, Ridley AJ.

PLoS One. 2010 Aug 25;5(8):e12393. doi: 10.1371/journal.pone.0012393.

41.

ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development.

Sottocornola R, Royer C, Vives V, Tordella L, Zhong S, Wang Y, Ratnayaka I, Shipman M, Cheung A, Gaston-Massuet C, Ferretti P, Molnár Z, Lu X.

Dev Cell. 2010 Jul 20;19(1):126-37. doi: 10.1016/j.devcel.2010.06.003. Epub 2010 Jul 8.

42.

Four-component reaction for the preparation of alpha-amino phosphonates from methyleneaziridines.

Mumford PM, Tarver GJ, Shipman M.

J Org Chem. 2009 May 1;74(9):3573-5. doi: 10.1021/jo9004958.

PMID:
19351179
43.

Synthesis of optically active arylaziridines by regio- and stereospecific lithiation of N-bus-phenylaziridine.

Musio B, Clarkson GJ, Shipman M, Florio S, Luisi R.

Org Lett. 2009 Jan 15;11(2):325-8. doi: 10.1021/ol802487v.

PMID:
19086905
44.

Rapid synthesis of 1,3,4,4-tetrasubstituted beta-lactams from methyleneaziridines using a four-component reaction.

Cariou CC, Clarkson GJ, Shipman M.

J Org Chem. 2008 Dec 19;73(24):9762-4. doi: 10.1021/jo801664g.

PMID:
18808185
45.

Umbrella motion in aziridines: use of simple chemical inputs to reversibly control the rate of pyramidal inversion.

Davies MW, Clarke AJ, Clarkson GJ, Shipman M, Tucker JH.

Chem Commun (Camb). 2007 Dec 21;(47):5078-80. Epub 2007 Oct 3.

PMID:
18049759
46.

Control of pyramidal inversion rates by redox switching.

Davies MW, Shipman M, Tucker JH, Walsh TR.

J Am Chem Soc. 2006 Nov 8;128(44):14260-1.

PMID:
17076491
47.

Fluoxetine treatment and testosterone levels.

Bell S, Shipman M, Bystritsky A, Haifley T.

Ann Clin Psychiatry. 2006 Jan-Mar;18(1):19-22.

PMID:
16517449
48.

Rapid generation of molecular complexity using "hybrid" multi-component reactions (MCRs): application to the synthesis of alpha-amino nitriles and 1,2-diamines.

Shiers JJ, Clarkson GJ, Shipman M, Hayes JF.

Chem Commun (Camb). 2006 Feb 14;(6):649-51. Epub 2006 Jan 6.

PMID:
16446839
49.

Solid-phase, multicomponent reactions of methyleneaziridines: synthesis of 1,3-disubstituted propanones.

Margathe JF, Shipman M, Smith SC.

Org Lett. 2005 Oct 27;7(22):4987-90.

PMID:
16235939
50.

Azinomycin inspired bisepoxides: influence of linker structure on in vitro cytotoxicity and DNA interstrand cross-linking.

LePla RC, Landreau CA, Shipman M, Hartley JA, Jones GD.

Bioorg Med Chem Lett. 2005 Jun 2;15(11):2861-4. Epub 2005 Apr 25.

PMID:
15911269

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