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Pralatrexate for refractory or recurrent subcutaneous panniculitis-like T-cell lymphoma with hemophagocytic syndrome.

Ware O, Tarabadkar ES, Shustov A, Shinohara MM.

J Am Acad Dermatol. 2019 Jul 15. pii: S0190-9622(19)32379-5. doi: 10.1016/j.jaad.2019.07.021. [Epub ahead of print] No abstract available.


Author Correction: Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu CC, Du D, Sun H, Wen L, Xu H, Bu G, Chen XF.

Nat Commun. 2019 Jul 2;10(1):2923. doi: 10.1038/s41467-019-10950-2.


Srs2 helicase prevents the formation of toxic DNA damage during late prophase I of yeast meiosis.

Sasanuma H, Sakurai HSM, Furihata Y, Challa K, Palmer L, Gasser SM, Shinohara M, Shinohara A.

Chromosoma. 2019 Jun 6. doi: 10.1007/s00412-019-00709-5. [Epub ahead of print]


How I treat primary cutaneous CD30+ lymphoproliferative disorders.

Shinohara MM, Shustov A.

Blood. 2019 Jun 4. pii: blood.2019000785. doi: 10.1182/blood.2019000785. [Epub ahead of print]


Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.

Mihara H, Kugawa M, Sayo K, Tao F, Shinohara M, Nishikawa M, Sakai Y, Akama T, Kojima N.

Cells. 2019 May 31;8(6). pii: E525. doi: 10.3390/cells8060525.


Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device.

Matsumoto S, Safitri AR, Danoy M, Maekawa T, Kinoshita H, Shinohara M, Sakai Y, Fujii T, Leclerc E.

Biotechnol Prog. 2019 May 26:e2854. doi: 10.1002/btpr.2854. [Epub ahead of print]


Corticospinal excitability for flexor carpi radialis decreases with baroreceptor unloading during intentional co-contraction with opposing forearm muscles.

Buharin VE, Shinohara M.

Exp Brain Res. 2019 Aug;237(8):1947-1958. doi: 10.1007/s00221-019-05563-6. Epub 2019 May 25.


Effects of establishing a trauma center on the mortality rate among injured pediatric patients in Japan.

Muguruma T, Toida C, Gakumazawa M, Yogo N, Shinohara M, Takeuchi I.

PLoS One. 2019 May 23;14(5):e0217140. doi: 10.1371/journal.pone.0217140. eCollection 2019.


HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma.

Sakata J, Hirosue A, Yoshida R, Kawahara K, Matsuoka Y, Yamamoto T, Nakamoto M, Hirayama M, Takahashi N, Nakamura T, Arita H, Nakashima H, Nagata M, Hiraki A, Shinohara M, Nakayama H.

Int J Mol Sci. 2019 May 19;20(10). pii: E2473. doi: 10.3390/ijms20102473.


The Roles of Apolipoprotein E, Lipids, and Glucose in the Pathogenesis of Alzheimer's Disease.

Shinohara M, Sato N.

Adv Exp Med Biol. 2019;1128:85-101. doi: 10.1007/978-981-13-3540-2_5.


Skin Directed Therapy in Cutaneous T-Cell Lymphoma.

Tarabadkar ES, Shinohara MM.

Front Oncol. 2019 Apr 11;9:260. doi: 10.3389/fonc.2019.00260. eCollection 2019. Review.


Flash Imaging Used in the Post-vascular Phase of Contrast-Enhanced Ultrasonography is Useful for Assessing the Progression in Patients with Hepatitis C Virus-Related Liver Disease.

Wakui N, Nagai H, Yoshimine N, Amanuma M, Kobayashi K, Ogino Y, Matsui D, Mukozu T, Matsukiyo Y, Matsui T, Daido Y, Momiyama K, Shinohara M, Kudo T, Maruyama K, Sumino Y, Igarashi Y.

Ultrasound Med Biol. 2019 Jul;45(7):1654-1662. doi: 10.1016/j.ultrasmedbio.2019.03.005. Epub 2019 Apr 25.


Influence of Sorafenib on Host Immunity in Patients with Liver Cirrhosis With Advanced Hepatocellular Carcinoma Stratified by Etiology.

Nagai H, Mukozu T, Kobayashi K, Amanuma M, Yoshimine N, Ogino YU, Matsui D, Daido Y, Matsukiyo Y, Matsui T, Wakui N, Momiyama K, Shinohara M, Higai K, Igarashi Y.

Anticancer Res. 2019 Apr;39(4):2183-2191. doi: 10.21873/anticanres.13333.


5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.

Shinohara M, Shinohara M, Zhao J, Fu Y, Liu CC, Kanekiyo T, Bu G.

Int J Mol Sci. 2019 Mar 25;20(6). pii: E1488. doi: 10.3390/ijms20061488.


Meiotic prophase-like pathway for cleavage-independent removal of cohesin for chromosome morphogenesis.

Challa K, Shinohara M, Shinohara A.

Curr Genet. 2019 Aug;65(4):817-827. doi: 10.1007/s00294-019-00959-x. Epub 2019 Mar 28. Review.


Soluble TREM2 ameliorates pathological phenotypes by modulating microglial functions in an Alzheimer's disease model.

Zhong L, Xu Y, Zhuo R, Wang T, Wang K, Huang R, Wang D, Gao Y, Zhu Y, Sheng X, Chen K, Wang N, Zhu L, Can D, Marten Y, Shinohara M, Liu CC, Du D, Sun H, Wen L, Xu H, Bu G, Chen XF.

Nat Commun. 2019 Mar 25;10(1):1365. doi: 10.1038/s41467-019-09118-9. Erratum in: Nat Commun. 2019 Jul 2;10(1):2923.


Circulating miRNA-1290 as a potential biomarker for response to chemoradiotherapy and prognosis of patients with advanced oral squamous cell carcinoma: A single-center retrospective study.

Nakashima H, Yoshida R, Hirosue A, Kawahara K, Sakata J, Arita H, Yamamoto T, Toya R, Murakami R, Hiraki A, Shinohara M, Ito T, Kuwahara Y, Nakayama H.

Tumour Biol. 2019 Mar;41(3):1010428319826853. doi: 10.1177/1010428319826853.


Identification of novel serum markers for the progression of coronary atherosclerosis in WHHLMI rabbits, an animal model of familial hypercholesterolemia.

Shiomi M, Takeda H, Irino Y, Kimura N, Yamada S, Kuniyoshi N, Kikumori A, Koike Y, Koike T, Yoshida M, Izumi Y, Shinohara M, Bamba T, Ishida T.

Atherosclerosis. 2019 May;284:18-23. doi: 10.1016/j.atherosclerosis.2019.02.020. Epub 2019 Feb 28.


Elevated Serum Elaidic Acid Predicts Risk of Repeat Revascularization After Percutaneous Coronary Intervention in Japan.

Oshita T, Toh R, Shinohara M, Mori K, Irino Y, Nagao M, Hara T, Otake H, Ishida T, Hirata KI.

Circ J. 2019 Apr 25;83(5):1032-1038. doi: 10.1253/circj.CJ-18-1175. Epub 2019 Mar 13.


Evaluation of duodenal perfusion by contrast-enhanced ultrasonography in dogs with chronic inflammatory enteropathy and intestinal lymphoma.

Nisa K, Lim SY, Shinohara M, Osuga T, Yokoyama N, Tamura M, Nagata N, Sasaoka K, Dermlim A, Leela-Arporn R, Morita T, Sasaki N, Morishita K, Nakamura K, Ohta H, Takiguchi M.

J Vet Intern Med. 2019 Mar;33(2):559-568. doi: 10.1111/jvim.15432. Epub 2019 Feb 19.


Feeding of 1-Kestose Induces Glutathione-S-Transferase Expression in Mouse Liver.

Tochio T, Ueno Y, Kitaura Y, Shinohara M, Kadota Y, Minoda K, Shimomura Y, Osawa T.

Foods. 2019 Feb 13;8(2). pii: E69. doi: 10.3390/foods8020069.


Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.

Yamazaki Y, Shinohara M, Shinohara M, Yamazaki A, Murray ME, Liesinger AM, Heckman MG, Lesser ER, Parisi JE, Petersen RC, Dickson DW, Kanekiyo T, Bu G.

Brain. 2019 Apr 1;142(4):1077-1092. doi: 10.1093/brain/awz011.


APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.

Tachibana M, Holm ML, Liu CC, Shinohara M, Aikawa T, Oue H, Yamazaki Y, Martens YA, Murray ME, Sullivan PM, Weyer K, Glerup S, Dickson DW, Bu G, Kanekiyo T.

J Clin Invest. 2019 Mar 1;129(3):1272-1277. doi: 10.1172/JCI124853. Epub 2019 Feb 11.


The management of numerous carcinomatous sequelae of human papilloma virus in an allogeneic stem cell transplant patient with chronic graft versus host disease.

Williams A, Gwinn C, Iyer J, Fleckman P, Shinohara MM.

JAAD Case Rep. 2019 Jan 28;5(2):162-166. doi: 10.1016/j.jdcr.2018.11.010. eCollection 2019 Feb. No abstract available.


Durable Tumor Regression and Overall Survival in Patients With Advanced Merkel Cell Carcinoma Receiving Pembrolizumab as First-Line Therapy.

Nghiem P, Bhatia S, Lipson EJ, Sharfman WH, Kudchadkar RR, Brohl AS, Friedlander PA, Daud A, Kluger HM, Reddy SA, Boulmay BC, Riker AI, Burgess MA, Hanks BA, Olencki T, Margolin K, Lundgren LM, Soni A, Ramchurren N, Church C, Park SY, Shinohara MM, Salim B, Taube JM, Bird SR, Ibrahim N, Fling SP, Homet Moreno B, Sharon E, Cheever MA, Topalian SL.

J Clin Oncol. 2019 Mar 20;37(9):693-702. doi: 10.1200/JCO.18.01896. Epub 2019 Feb 6.


Normative parameters and anthropometric variability of lumbar muscle stiffness using ultrasound shear-wave elastography.

Koppenhaver SL, Scutella D, Sorrell BA, Yahalom J, Fernández-de-Las-Peñas C, Childs JD, Shaffer SW, Shinohara M.

Clin Biomech (Bristol, Avon). 2019 Feb;62:113-120. doi: 10.1016/j.clinbiomech.2019.01.010. Epub 2019 Jan 30.


Meiosis-specific prophase-like pathway controls cleavage-independent release of cohesin by Wapl phosphorylation.

Challa K, Fajish V G, Shinohara M, Klein F, Gasser SM, Shinohara A.

PLoS Genet. 2019 Jan 3;15(1):e1007851. doi: 10.1371/journal.pgen.1007851. eCollection 2019 Jan.


Demographics, Comorbid Conditions, and Outcomes of Patients With Nonuremic Calciphylaxis.

Altman K, Shinohara M.

JAMA Dermatol. 2019 Jan 2. doi: 10.1001/jamadermatol.2018.4937. [Epub ahead of print] No abstract available.


Postprandial Plasma Glucagon Kinetics in Type 2 Diabetes Mellitus: Comparison of Immunoassay and Mass Spectrometry.

Katahira T, Kanazawa A, Shinohara M, Koshibu M, Kaga H, Mita T, Tosaka Y, Komiya K, Miyatsuka T, Ikeda F, Azuma K, Takayanagi N, Ogihara T, Ohmura C, Miyachi A, Mieno E, Yamashita S, Watada H.

J Endocr Soc. 2018 Oct 26;3(1):42-51. doi: 10.1210/js.2018-00142. eCollection 2019 Jan 1.


Understanding mechanisms underlying the pathology of immune reconstitution inflammatory syndrome (IRIS) by using animal models.

Aggarwal N, Barclay W, Shinohara ML.

Curr Clin Microbiol Rep. 2018 Sep;5(3):201-209. doi: 10.1007/s40588-018-0099-5. Epub 2018 Jun 22.


Gut Microbiome and Plasma Microbiome-Related Metabolites in Patients With Decompensated and Compensated Heart Failure.

Hayashi T, Yamashita T, Watanabe H, Kami K, Yoshida N, Tabata T, Emoto T, Sasaki N, Mizoguchi T, Irino Y, Toh R, Shinohara M, Okada Y, Ogawa W, Yamada T, Hirata KI.

Circ J. 2018 Dec 25;83(1):182-192. doi: 10.1253/circj.CJ-18-0468. Epub 2018 Nov 29.


Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy.

Miller NJ, Church CD, Fling SP, Kulikauskas R, Ramchurren N, Shinohara MM, Kluger HM, Bhatia S, Lundgren L, Cheever MA, Topalian SL, Nghiem P.

J Immunother Cancer. 2018 Nov 27;6(1):131. doi: 10.1186/s40425-018-0450-7.


Are Neuropeptide-Reactive T Cells behind Narcolepsy?

Deerhake ME, Barclay WE, Shinohara ML.

Immunity. 2018 Nov 20;49(5):796-798. doi: 10.1016/j.immuni.2018.11.002.


Utility of Skin Biopsy and Culture in the Diagnosis and Classification of Chronic Ulcers: A Single-Institution, Retrospective Study.

Khoobyari S, Miller TI, Shinohara MM.

Am J Dermatopathol. 2019 May;41(5):343-346. doi: 10.1097/DAD.0000000000001299.


Meiosis-specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope.

Bommi JR, Rao HBDP, Challa K, Higashide M, Shinmyozu K, Nakayama JI, Shinohara M, Shinohara A.

Genes Cells. 2019 Jan;24(1):94-106. doi: 10.1111/gtc.12653. Epub 2018 Dec 12.


The relationship between serum indoxyl sulfate and the renal function after catheter ablation of atrial fibrillation in patients with mild renal dysfunction.

Koike H, Morita T, Tatebe J, Watanabe I, Koike M, Yao S, Shinohara M, Yuzawa H, Suzuki T, Fujino T, Ikeda T.

Heart Vessels. 2019 Apr;34(4):641-649. doi: 10.1007/s00380-018-1288-0. Epub 2018 Nov 8.


Right Ventricular Septal Pacing Using a Thin Lumenless Pacing Lead and Delivery System with a Deflectable Catheter.

Suzuki T, Fujino T, Shinohara M, Koike H, Kinoshita T, Yuzawa H, Ikeda T.

Int Heart J. 2018 Nov 28;59(6):1253-1260. doi: 10.1536/ihj.17-526. Epub 2018 Nov 5.


APOE ε2 is associated with increased tau pathology in primary tauopathy.

Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, Caselli RJ, Sanchez-Contreras MY, Rademakers R, Murray ME, Koga S, Dickson DW, Ross OA, Bu G.

Nat Commun. 2018 Oct 22;9(1):4388. doi: 10.1038/s41467-018-06783-0.


Usefulness of multidisciplinary care to prevent worsening renal function in chronic kidney disease.

Imamura Y, Takahashi Y, Hayashi T, Iwamoto M, Nakamura R, Goto M, Takeba K, Shinohara M, Kubo S, Joki N.

Clin Exp Nephrol. 2019 Apr;23(4):484-492. doi: 10.1007/s10157-018-1658-z. Epub 2018 Oct 19.


Progressive, Painful Erosions of the Face, Neck, and Lips: Answer.

May C, Shinohara M.

Am J Dermatopathol. 2018 Nov;40(11):857-858. doi: 10.1097/DAD.0000000000000979. No abstract available.


Association between venous blood lactate levels and differences in quantitative capillary refill time.

Oi Y, Sato K, Nogaki A, Shinohara M, Matsumoto J, Abe T, Morimura N.

Acute Med Surg. 2018 Jun 5;5(4):321-328. doi: 10.1002/ams2.348. eCollection 2018 Oct.


Comparative metabolomics of Japanese Black cattle beef and other meats using gas chromatography-mass spectrometry.

Ueda S, Iwamoto E, Kato Y, Shinohara M, Shirai Y, Yamanoue M.

Biosci Biotechnol Biochem. 2018 Oct 18:1-11. doi: 10.1080/09168451.2018.1528139. [Epub ahead of print]


Generalized fixed drug eruption mimicking CD8+ cutaneous T-cell lymphoma in HIV.

Jacobsen E, Tarabadkar ES, Shinohara MM.

J Cutan Pathol. 2019 Feb;46(2):134-137. doi: 10.1111/cup.13376. Epub 2018 Nov 14.


A case of Vogt-Koyanagi-Harada disease as a sequela of drug reaction with eosinophilia and systemic symptoms.

Altman K, Shinohara M.

JAAD Case Rep. 2018 Oct 3;4(9):863-865. doi: 10.1016/j.jdcr.2018.06.019. eCollection 2018 Oct. No abstract available.


Hepatic arterialization can predict the development of collateral veins in patients with HCV-related liver disease.

Wakui N, Nagai H, Ogino Y, Kobayashi K, Matsui D, Mukozu T, Matsukiyo Y, Matsui T, Daido Y, Momiyama K, Shinohara M, Kudo T, Maruyama K, Sumino Y, Igarashi Y.

J Ultrasound. 2018 Dec;21(4):301-308. doi: 10.1007/s40477-018-0323-4. Epub 2018 Oct 5.


Modulation of lipid mediator profile may contribute to amelioration of chronic inflammation in adipose tissue of obese mice by pioglitazone.

Okada K, Hosooka T, Shinohara M, Ogawa W.

Biochem Biophys Res Commun. 2018 Oct 20;505(1):29-35. doi: 10.1016/j.bbrc.2018.09.081. Epub 2018 Sep 17.


Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma.

Bhatia S, Miller NJ, Lu H, Longino NV, Ibrani D, Shinohara MM, Byrd DR, Parvathaneni U, Kulikauskas R, Ter Meulen J, Hsu FJ, Koelle DM, Nghiem P.

Clin Cancer Res. 2019 Feb 15;25(4):1185-1195. doi: 10.1158/1078-0432.CCR-18-0469. Epub 2018 Aug 9.


Panniculitis in a patient with pathologic complete response to talimogene laherparepvec treatment for recurrent, in-transit melanoma.

Long TH, Shinohara MM, Argenyi ZB, Thompson JA, Gardner JM.

J Cutan Pathol. 2018 Nov;45(11):864-868. doi: 10.1111/cup.13332. Epub 2018 Aug 22.


Efficient functional cyst formation of biliary epithelial cells using microwells for potential bile duct organisation in vitro.

Rizki-Safitri A, Shinohara M, Miura Y, Danoy M, Tanaka M, Miyajima A, Sakai Y.

Sci Rep. 2018 Jul 23;8(1):11086. doi: 10.1038/s41598-018-29464-w.


Randomized controlled trial of an oral appliance (SomnoDent) for sleep-disordered breathing and cardiac function in patients with heart failure.

Matsumoto H, Kasai T, Suda S, Yatsu S, Shitara J, Murata A, Kato T, Hiki M, Yanagisawa N, Fujibayashi K, Nojiri S, Nishizaki Y, Shinohara M, Daida H.

Clin Cardiol. 2018 Aug;41(8):1009-1012. doi: 10.1002/clc.23028. Epub 2018 Aug 16.

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