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Items: 1 to 50 of 142

1.

Comparison of feeding habits and habitat use between invasive raccoons and native raccoon dogs in Hokkaido, Japan.

Osaki A, Sashika M, Abe G, Shinjo K, Fujimoto A, Nakai M, Shimozuru M, Tsubota T.

BMC Ecol. 2019 Sep 11;19(1):35. doi: 10.1186/s12898-019-0249-5.

2.

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.

Ohka F, Shinjo K, Deguchi S, Matsui Y, Okuno Y, Katsushima K, Suzuki M, Kato A, Ogiso N, Yamamichi A, Aoki K, Suzuki H, Sato S, Arul Rayan N, Prabhakar S, Göke J, Shimamura T, Maruyama R, Takahashi S, Suzumura A, Kimura H, Wakabayashi T, Zong H, Natsume A, Kondo Y.

Cancer Res. 2019 Oct 1;79(19):4814-4827. doi: 10.1158/0008-5472.CAN-19-1272. Epub 2019 Aug 20.

PMID:
31431463
3.

DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes5.

Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, Shinjo K, Kondo Y, Sobue G, Katsuno M.

EMBO Mol Med. 2019 May;11(5). pii: e8547. doi: 10.15252/emmm.201708547.

4.

Identification of a chemical modulator of EZH2-mediated silencing by cell-based high-throughput screening assay.

Murashima A, Shinjo K, Katsushima K, Onuki T, Kondoh Y, Osada H, Kagaya N, Shin-Ya K, Kimura H, Yoshida M, Murakami S, Kondo Y.

J Biochem. 2019 Jul 1;166(1):41-50. doi: 10.1093/jb/mvz007.

PMID:
30690451
5.

ZNF671 DNA methylation as a molecular predictor for the early recurrence of serous ovarian cancer.

Mase S, Shinjo K, Totani H, Katsushima K, Arakawa A, Takahashi S, Lai HC, Lin RI, Chan MWY, Sugiura-Ogasawara M, Kondo Y.

Cancer Sci. 2019 Mar;110(3):1105-1116. doi: 10.1111/cas.13936. Epub 2019 Jan 31.

6.

Treatment satisfaction with pharmaceutical interventions in Japanese adults with osteoarthritis and chronic knee pain: an analysis of a web-based survey.

Ueda K, Sasaki N, Goren A, Calhoun SR, Shinjo K, Enomoto H, Muneta T.

Clin Interv Aging. 2018 Oct 26;13:2179-2191. doi: 10.2147/CIA.S176289. eCollection 2018.

7.

A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR.

Hirano M, Ohka F, Maeda S, Chalise L, Yamamichi A, Aoki K, Kato A, Tanahashi K, Motomura K, Nishimura Y, Hara M, Shinjo K, Kondo Y, Wakabayashi T, Natsume A.

Brain Tumor Pathol. 2018 Apr;35(2):97-105. doi: 10.1007/s10014-018-0310-7. Epub 2018 Feb 19.

PMID:
29460200
8.

Long non-coding RNAs as an epigenetic regulator in human cancers.

Kondo Y, Shinjo K, Katsushima K.

Cancer Sci. 2017 Oct;108(10):1927-1933. doi: 10.1111/cas.13342. Epub 2017 Aug 30. Review.

9.

Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis.

Deguchi S, Katsushima K, Hatanaka A, Shinjo K, Ohka F, Wakabayashi T, Zong H, Natsume A, Kondo Y.

Oncogene. 2017 Aug 10;36(32):4629-4640. doi: 10.1038/onc.2017.88. Epub 2017 Apr 3.

PMID:
28368417
10.

Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.

Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, Sato S, Takahashi S, Kimura H, Totoki Y, Shibata T, Naito M, Kim HJ, Miyata K, Kataoka K, Kondo Y.

Nat Commun. 2016 Dec 6;7:13616. doi: 10.1038/ncomms13616.

11.

Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma.

Fujii S, Shinjo K, Matsumoto S, Harada T, Nojima S, Sato S, Usami Y, Toyosawa S, Morii E, Kondo Y, Kikuchi A.

Oncotarget. 2016 Dec 6;7(49):81571-81587. doi: 10.18632/oncotarget.13147.

12.

Histone Deacetylase Inhibition in Prostate Cancer Triggers miR-320-Mediated Suppression of the Androgen Receptor.

Sato S, Katsushima K, Shinjo K, Hatanaka A, Ohka F, Suzuki S, Naiki-Ito A, Soga N, Takahashi S, Kondo Y.

Cancer Res. 2016 Jul 15;76(14):4192-204. doi: 10.1158/0008-5472.CAN-15-3339. Epub 2016 May 23.

13.

Biliary hemostasis using an endoscopic plastic stent placement for uncontrolled hemobilia caused by transpapillary forceps biopsy (with video).

Shinjo K, Matsubayashi H, Matsui T, Kawata N, Uemura S, Yamamoto Y, Ono H.

Clin J Gastroenterol. 2016 Apr;9(2):86-8. doi: 10.1007/s12328-016-0637-8. Epub 2016 Mar 10.

PMID:
26960930
14.

Enhanced effect of BCG vaccine against pulmonary Mycobacterium tuberculosis infection in mice with lung Th17 response to mycobacterial heparin-binding hemagglutinin adhesin antigen.

Fukui M, Shinjo K, Umemura M, Shigeno S, Harakuni T, Arakawa T, Matsuzaki G.

Microbiol Immunol. 2015 Dec;59(12):735-43. doi: 10.1111/1348-0421.12340.

15.

Targeting cancer epigenetics: Linking basic biology to clinical medicine.

Shinjo K, Kondo Y.

Adv Drug Deliv Rev. 2015 Dec 1;95:56-64. doi: 10.1016/j.addr.2015.10.006. Epub 2015 Oct 19. Review.

PMID:
26494398
16.

Muscle stiffness estimation using a system identification technique applied to evoked mechanomyogram during cycling exercise.

Uchiyama T, Saito K, Shinjo K.

J Electromyogr Kinesiol. 2015 Dec;25(6):847-52. doi: 10.1016/j.jelekin.2015.09.005. Epub 2015 Oct 9.

PMID:
26493234
17.

Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.

Ichimura N, Shinjo K, An B, Shimizu Y, Yamao K, Ohka F, Katsushima K, Hatanaka A, Tojo M, Yamamoto E, Suzuki H, Ueda M, Kondo Y.

Cancer Prev Res (Phila). 2015 Aug;8(8):702-11. doi: 10.1158/1940-6207.CAPR-14-0306. Epub 2015 Jun 10.

18.

Endoscopic foreign body retrieval using laparoscopic shears after gastrostomy.

Shinjo K, Sato K, Tada T, Maekawa H, Sakurada M, Orita H, Ito T, Saita M, Sugimoto K.

Turk J Gastroenterol. 2014 Dec;25 Suppl 1:304-5. doi: 10.5152/tjg.2014.3915. No abstract available.

19.

Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F₂ male offspring via the F₁ male offspring.

Nohara K, Okamura K, Suzuki T, Murai H, Ito T, Shinjo K, Takumi S, Michikawa T, Kondo Y, Hata K.

J Appl Toxicol. 2016 Jan;36(1):105-12. doi: 10.1002/jat.3149. Epub 2015 Mar 30.

PMID:
25825268
20.

Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.

Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y.

PLoS One. 2015 Feb 6;10(2):e0115350. doi: 10.1371/journal.pone.0115350. eCollection 2015.

21.

Identification of causative pregnancy of gestational trophoblastic neoplasia diagnosed during pregnancy by short tandem repeat analysis.

Yamamoto E, Niimi K, Shinjo K, Yamamoto T, Fukunaga M, Kikkawa F.

Gynecol Oncol Case Rep. 2014 Apr 18;9:3-6. doi: 10.1016/j.gynor.2014.04.001. eCollection 2014 Aug.

22.

Epigenetic dysregulation in glioma.

Kondo Y, Katsushima K, Ohka F, Natsume A, Shinjo K.

Cancer Sci. 2014 Apr;105(4):363-9. Review.

23.

miR-615-5p is epigenetically inactivated and functions as a tumor suppressor in pancreatic ductal adenocarcinoma.

Gao W, Gu Y, Li Z, Cai H, Peng Q, Tu M, Kondo Y, Shinjo K, Zhu Y, Zhang J, Sekido Y, Han B, Qian Z, Miao Y.

Oncogene. 2015 Mar 26;34(13):1629-40. doi: 10.1038/onc.2014.101. Epub 2014 Apr 28.

PMID:
24769899
24.

Expression of chromobox homolog 7 (CBX7) is associated with poor prognosis in ovarian clear cell adenocarcinoma via TRAIL-induced apoptotic pathway regulation.

Shinjo K, Yamashita Y, Yamamoto E, Akatsuka S, Uno N, Kamiya A, Niimi K, Sakaguchi Y, Nagasaka T, Takahashi T, Shibata K, Kajiyama H, Kikkawa F, Toyokuni S.

Int J Cancer. 2014 Jul 15;135(2):308-18. doi: 10.1002/ijc.28692. Epub 2014 Jan 10.

25.

Endoscopic ultrasound-guided retrograde pancreatic stent placement for the treatment of stenotic jejunopancreatic anastomosis after a Whipple procedure.

Matsubayashi H, Kishida Y, Shinjo K, Imai K, Hotta K, Tanaka M, Kakushima N, Takizawa K, Mizuno T, Okamura Y, Ono H.

Endoscopy. 2013;45 Suppl 2 UCTN:E435-6. doi: 10.1055/s-0033-1358923. Epub 2013 Dec 13. No abstract available.

PMID:
24338178
26.

RASSF3 downregulation increases malignant phenotypes of non-small cell lung cancer.

Fukatsu A, Ishiguro F, Tanaka I, Kudo T, Nakagawa K, Shinjo K, Kondo Y, Fujii M, Hasegawa Y, Tomizawa K, Mitsudomi T, Osada H, Hata Y, Sekido Y.

Lung Cancer. 2014 Jan;83(1):23-9. doi: 10.1016/j.lungcan.2013.10.014. Epub 2013 Oct 31.

PMID:
24246507
27.

Hepatitis virus infection affects DNA methylation in mice with humanized livers.

Okamoto Y, Shinjo K, Shimizu Y, Sano T, Yamao K, Gao W, Fujii M, Osada H, Sekido Y, Murakami S, Tanaka Y, Joh T, Sato S, Takahashi S, Wakita T, Zhu J, Issa JP, Kondo Y.

Gastroenterology. 2014 Feb;146(2):562-72. doi: 10.1053/j.gastro.2013.10.056. Epub 2013 Oct 30.

PMID:
24184133
28.

Determination of steroid response by abdominal ultrasound in cases with autoimmune pancreatitis.

Matsubayashi H, Yoneyama M, Nanri K, Sugimoto S, Shinjo K, Kakushima N, Tanaka M, Ito S, Takao M, Ono H.

Dig Liver Dis. 2013 Dec;45(12):1034-40. doi: 10.1016/j.dld.2013.06.006. Epub 2013 Jul 29.

PMID:
23906519
29.

Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma.

Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, Issa JP, Sekido Y, Kondo Y.

Cancer Res. 2013 Jul 15;73(14):4559-70. doi: 10.1158/0008-5472.CAN-13-0109. Epub 2013 May 29.

30.

Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.

Yamashita Y, Akatsuka S, Shinjo K, Yatabe Y, Kobayashi H, Seko H, Kajiyama H, Kikkawa F, Takahashi T, Toyokuni S.

PLoS One. 2013;8(3):e57724. doi: 10.1371/journal.pone.0057724. Epub 2013 Mar 4.

31.

High expression of N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma.

Niimi K, Yamamoto E, Fujiwara S, Shinjo K, Kotani T, Umezu T, Kajiyama H, Shibata K, Ino K, Kikkawa F.

Br J Cancer. 2012 Dec 4;107(12):1969-77. doi: 10.1038/bjc.2012.496. Epub 2012 Nov 20.

32.

Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells.

Katsushima K, Shinjo K, Natsume A, Ohka F, Fujii M, Osada H, Sekido Y, Kondo Y.

J Biol Chem. 2012 Aug 10;287(33):27396-406. doi: 10.1074/jbc.M112.359109. Epub 2012 Jun 26.

33.

Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma.

Shinjo K, Okamoto Y, An B, Yokoyama T, Takeuchi I, Fujii M, Osada H, Usami N, Hasegawa Y, Ito H, Hida T, Fujimoto N, Kishimoto T, Sekido Y, Kondo Y.

Carcinogenesis. 2012 Jul;33(7):1277-85. doi: 10.1093/carcin/bgs154. Epub 2012 Apr 24.

PMID:
22532250
34.

Clinical implications of epigenetic alterations in human thoracic malignancies: epigenetic alterations in lung cancer.

Shinjo K, Kondo Y.

Methods Mol Biol. 2012;863:221-39. doi: 10.1007/978-1-61779-612-8_13. Review.

PMID:
22359296
35.

Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses.

Kishida Y, Natsume A, Kondo Y, Takeuchi I, An B, Okamoto Y, Shinjo K, Saito K, Ando H, Ohka F, Sekido Y, Wakabayashi T.

Carcinogenesis. 2012 Feb;33(2):436-41. doi: 10.1093/carcin/bgr260. Epub 2011 Nov 18.

PMID:
22102699
36.

Aberrant DNA methylation associated with aggressiveness of gastrointestinal stromal tumour.

Okamoto Y, Sawaki A, Ito S, Nishida T, Takahashi T, Toyota M, Suzuki H, Shinomura Y, Takeuchi I, Shinjo K, An B, Ito H, Yamao K, Fujii M, Murakami H, Osada H, Kataoka H, Joh T, Sekido Y, Kondo Y.

Gut. 2012 Mar;61(3):392-401. doi: 10.1136/gut.2011.241034. Epub 2011 Jun 27.

PMID:
21708825
37.

Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis.

Ju HX, An B, Okamoto Y, Shinjo K, Kanemitsu Y, Komori K, Hirai T, Shimizu Y, Sano T, Sawaki A, Tajika M, Yamao K, Fujii M, Murakami H, Osada H, Ito H, Takeuchi I, Sekido Y, Kondo Y.

Am J Pathol. 2011 Apr;178(4):1835-46. doi: 10.1016/j.ajpath.2010.12.045. Epub 2011 Mar 4.

38.

[Targeting epigenetics plasticity as a novel target for human neoplasia].

Shinjo K, Kondo Y.

Gan To Kagaku Ryoho. 2010 Sep;37(9):1654-8. Japanese.

PMID:
20841927
39.

Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers.

An B, Kondo Y, Okamoto Y, Shinjo K, Kanemitsu Y, Komori K, Hirai T, Sawaki A, Tajika M, Nakamura T, Yamao K, Yatabe Y, Fujii M, Murakami H, Osada H, Tani T, Matsuo K, Shen L, Issa JP, Sekido Y.

Int J Cancer. 2010 Nov 1;127(9):2095-105. doi: 10.1002/ijc.25225.

40.

Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma.

Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y.

Cancer Res. 2009 Dec 1;69(23):9073-82. doi: 10.1158/0008-5472.CAN-09-1595. Epub 2009 Nov 3.

41.

[Biological markers for diagnosis of myeloid leukemia].

Takeshita A, Shinjo K.

Nihon Rinsho. 2009 Oct;67(10):1916-20. Review. Japanese.

PMID:
19860190
42.

Gene expression profiling and functional assays of activated hepatic stellate cells suggest that myocardin has a role in activation.

Shimada H, Ochi T, Imasato A, Morizane Y, Hori M, Ozaki H, Shinjo K.

Liver Int. 2010 Jan;30(1):42-54. doi: 10.1111/j.1478-3231.2009.02120.x. Epub 2009 Sep 28.

PMID:
19793196
43.

CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma.

Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R.

Br J Haematol. 2009 Jun;146(1):34-43. doi: 10.1111/j.1365-2141.2009.07701.x. Epub 2009 Apr 13.

PMID:
19388933
44.

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells.

Takeshita A, Yamakage N, Shinjo K, Ono T, Hirano I, Nakamura S, Shigeno K, Tobita T, Maekawa M, Kiyoi H, Naoe T, Ohnishi K, Sugimoto Y, Ohno R.

Leukemia. 2009 Jul;23(7):1329-36. doi: 10.1038/leu.2009.77. Epub 2009 Apr 16. Erratum in: Leukemia. 2009 Jul;23(7):1372.

PMID:
19369961
45.

Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt isoforms.

Hirano I, Nakamura S, Yokota D, Ono T, Shigeno K, Fujisawa S, Shinjo K, Ohnishi K.

J Biol Chem. 2009 Aug 14;284(33):22155-65. doi: 10.1074/jbc.M808182200. Epub 2009 Mar 4.

46.

Activation of the PI3K-AKT pathway in human malignant mesothelioma cells.

Suzuki Y, Murakami H, Kawaguchi K, Tanigushi T, Fujii M, Shinjo K, Kondo Y, Osada H, Shimokata K, Horio Y, Hasegawa Y, Hida T, Sekido Y.

Mol Med Rep. 2009 Mar-Apr;2(2):181-8. doi: 10.3892/mmr_00000081.

PMID:
21475810
47.

Selective CB1 cannabinoid receptor antagonist, SR141716A, attenuates liver injury induced by Concanavalin A.

Kojima M, Kato N, Hirano D, Ochi T, Nii A, Shinjo K, Eda H.

Hepatol Res. 2009 Apr;39(4):408-14. doi: 10.1111/j.1872-034X.2008.00473.x. Epub 2008 Dec 19.

PMID:
19207577
48.

Apoptosis signal-regulating kinase 1 is crucial for oxidative stress-induced but not for osmotic stress-induced hepatocyte cell death.

Taki K, Shimozono R, Kusano H, Suzuki N, Shinjo K, Eda H.

Life Sci. 2008 Dec 19;83(25-26):859-64. doi: 10.1016/j.lfs.2008.10.004. Epub 2008 Oct 21.

PMID:
18983857
49.

Utility of plasma circulating mRNA as a marker to detect hepatic injury.

Kudo Y, Ochi T, Shimada H, Ogawa S, Shinjo K.

J Vet Med Sci. 2008 Sep;70(9):993-5.

50.

5-Nitro-2-(3-phenylpropylamino)benzoic acid is a GPR35 agonist.

Taniguchi Y, Tonai-Kachi H, Shinjo K.

Pharmacology. 2008;82(4):245-9. doi: 10.1159/000157625. Epub 2008 Sep 26.

PMID:
18818509

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