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Items: 1 to 50 of 71

1.

The Y233 gatekeeper of DmpR modulates effector-responsive transcriptional control of σ54 -RNA polymerase.

Seibt H, Sauer UH, Shingler V.

Environ Microbiol. 2019 Apr;21(4):1321-1330. doi: 10.1111/1462-2920.14567. Epub 2019 Mar 7.

PMID:
30773776
2.

PP4397/FlgZ provides the link between PP2258 c-di-GMP signalling and altered motility in Pseudomonas putida.

Wirebrand L, Österberg S, López-Sánchez A, Govantes F, Shingler V.

Sci Rep. 2018 Aug 15;8(1):12205. doi: 10.1038/s41598-018-29785-w.

3.

The stringent response promotes biofilm dispersal in Pseudomonas putida.

Díaz-Salazar C, Calero P, Espinosa-Portero R, Jiménez-Fernández A, Wirebrand L, Velasco-Domínguez MG, López-Sánchez A, Shingler V, Govantes F.

Sci Rep. 2017 Dec 22;7(1):18055. doi: 10.1038/s41598-017-18518-0.

4.

Multiple Hfq-Crc target sites are required to impose catabolite repression on (methyl)phenol metabolism in Pseudomonas putida CF600.

Wirebrand L, Madhushani AWK, Irie Y, Shingler V.

Environ Microbiol. 2018 Jan;20(1):186-199. doi: 10.1111/1462-2920.13966. Epub 2017 Dec 1.

PMID:
29076626
5.

Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA.

Beljantseva J, Kudrin P, Andresen L, Shingler V, Atkinson GC, Tenson T, Hauryliuk V.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3726-3731. doi: 10.1073/pnas.1617868114. Epub 2017 Mar 20.

6.

Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor.

Beljantseva J, Kudrin P, Jimmy S, Ehn M, Pohl R, Varik V, Tozawa Y, Shingler V, Tenson T, Rejman D, Hauryliuk V.

Sci Rep. 2017 Feb 3;7:41839. doi: 10.1038/srep41839.

7.

Inter-sigmulon communication through topological promoter coupling.

Del Peso Santos T, Shingler V.

Nucleic Acids Res. 2016 Nov 16;44(20):9638-9649. Epub 2016 Jul 15.

8.

Transcriptional and translational control through the 5'-leader region of the dmpR master regulatory gene of phenol metabolism.

Madhushani A, Del Peso-Santos T, Moreno R, Rojo F, Shingler V.

Environ Microbiol. 2015 Jan;17(1):119-33. doi: 10.1111/1462-2920.12511. Epub 2014 Jun 25.

PMID:
24889314
9.

The Crc and Hfq proteins of Pseudomonas putida cooperate in catabolite repression and formation of ribonucleic acid complexes with specific target motifs.

Moreno R, Hernández-Arranz S, La Rosa R, Yuste L, Madhushani A, Shingler V, Rojo F.

Environ Microbiol. 2015 Jan;17(1):105-18. doi: 10.1111/1462-2920.12499. Epub 2014 Jun 2.

PMID:
24803210
10.

AccR is a master regulator involved in carbon catabolite repression of the anaerobic catabolism of aromatic compounds in Azoarcus sp. CIB.

Valderrama JA, Shingler V, Carmona M, Díaz E.

J Biol Chem. 2014 Jan 24;289(4):1892-904. doi: 10.1074/jbc.M113.517714. Epub 2013 Dec 3.

11.

An A-tract at the AtzR binding site assists DNA binding, inducer-dependent repositioning and transcriptional activation of the PatzDEF promoter.

Porrúa O, López-Sánchez A, Platero AI, Santero E, Shingler V, Govantes F.

Mol Microbiol. 2013 Oct;90(1):72-87. doi: 10.1111/mmi.12346. Epub 2013 Aug 15.

12.

Genetic dissection of a motility-associated c-di-GMP signalling protein of Pseudomonas putida.

Österberg S, Åberg A, Herrera Seitz MK, Wolf-Watz M, Shingler V.

Environ Microbiol Rep. 2013 Aug;5(4):556-65. doi: 10.1111/1758-2229.12045. Epub 2013 Mar 22.

PMID:
23864570
13.

Characterization of the transcriptional stimulatory properties of the Pseudomonas putida RapA protein.

Stec-Dziedzic E, Lyżeń R, Skärfstad E, Shingler V, Szalewska-Pałasz A.

Biochim Biophys Acta. 2013 Feb;1829(2):219-30. doi: 10.1016/j.bbagrm.2012.11.008. Epub 2012 Nov 30.

PMID:
23207688
14.

Pr is a member of a restricted class of σ70-dependent promoters that lack a recognizable -10 element.

Del Peso-Santos T, Landfors M, Skärfstad E, Ryden P, Shingler V.

Nucleic Acids Res. 2012 Dec;40(22):11308-20. doi: 10.1093/nar/gks934. Epub 2012 Oct 11.

15.

Regulation of alternative sigma factor use.

Österberg S, del Peso-Santos T, Shingler V.

Annu Rev Microbiol. 2011;65:37-55. doi: 10.1146/annurev.micro.112408.134219. Review.

PMID:
21639785
16.

A hyper-mutant of the unusual sigma70-Pr promoter bypasses synergistic ppGpp/DksA co-stimulation.

Del Peso-Santos T, Bernardo LM, Skärfstad E, Holmfeldt L, Togneri P, Shingler V.

Nucleic Acids Res. 2011 Aug;39(14):5853-65. doi: 10.1093/nar/gkr167. Epub 2011 Mar 29.

17.

Signal sensory systems that impact σ⁵⁴ -dependent transcription.

Shingler V.

FEMS Microbiol Rev. 2011 May;35(3):425-40. doi: 10.1111/j.1574-6976.2010.00255.x. Epub 2010 Nov 5. Review.

18.

Physiological and transcriptomic characterization of a fliA mutant of Pseudomonas putida KT2440.

Rodríguez-Herva JJ, Duque E, Molina-Henares MA, Navarro-Avilés G, Van Dillewijn P, De La Torre J, Molina-Henares AJ, La Campa AS, Ran FA, Segura A, Shingler V, Ramos JL.

Environ Microbiol Rep. 2010 Jun;2(3):373-80. doi: 10.1111/j.1758-2229.2009.00084.x. Epub 2009 Oct 7.

PMID:
23766109
19.

The sigma-factor FliA, ppGpp and DksA coordinate transcriptional control of the aer2 gene of Pseudomonas putida.

Osterberg S, Skärfstad E, Shingler V.

Environ Microbiol. 2010 Jun;12(6):1439-51. doi: 10.1111/j.1462-2920.2009.02139.x. Epub 2010 Jan 18.

PMID:
20089044
20.

Activation and repression of a sigmaN-dependent promoter naturally lacking upstream activation sequences.

Porrúa O, García-González V, Santero E, Shingler V, Govantes F.

Mol Microbiol. 2009 Aug;73(3):419-33. doi: 10.1111/j.1365-2958.2009.06779.x. Epub 2009 Jun 29.

21.

sigma54-promoter discrimination and regulation by ppGpp and DksA.

Bernardo LM, Johansson LU, Skärfstad E, Shingler V.

J Biol Chem. 2009 Jan 9;284(2):828-38. doi: 10.1074/jbc.M807707200. Epub 2008 Nov 13.

22.

sigma54-RNA polymerase controls sigma70-dependent transcription from a non-overlapping divergent promoter.

Johansson LU, Solera D, Bernardo LM, Moscoso JA, Shingler V.

Mol Microbiol. 2008 Nov;70(3):709-23. doi: 10.1111/j.1365-2958.2008.06440.x. Epub 2008 Sep 10.

24.

Regulation of the fimB promoter: a case of differential regulation by ppGpp and DksA in vivo.

Aberg A, Shingler V, Balsalobre C.

Mol Microbiol. 2008 Mar;67(6):1223-41. doi: 10.1111/j.1365-2958.2008.06115.x. Epub 2008 Feb 13.

25.

Metabolism-dependent taxis towards (methyl)phenols is coupled through the most abundant of three polar localized Aer-like proteins of Pseudomonas putida.

Sarand I, Osterberg S, Holmqvist S, Holmfeldt P, Skärfstad E, Parales RE, Shingler V.

Environ Microbiol. 2008 May;10(5):1320-34. doi: 10.1111/j.1462-2920.2007.01546.x. Epub 2008 Feb 12.

PMID:
18279347
26.

Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54.

Szalewska-Palasz A, Johansson LU, Bernardo LM, Skärfstad E, Stec E, Brännström K, Shingler V.

J Biol Chem. 2007 Jun 22;282(25):18046-56. Epub 2007 Apr 24.

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28.

Coregulation by phenylacetyl-coenzyme A-responsive PaaX integrates control of the upper and lower pathways for catabolism of styrene by Pseudomonas sp. strain Y2.

del Peso-Santos T, Bartolomé-Martín D, Fernández C, Alonso S, García JL, Díaz E, Shingler V, Perera J.

J Bacteriol. 2006 Jul;188(13):4812-21.

29.

The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription.

Bernardo LM, Johansson LU, Solera D, Skärfstad E, Shingler V.

Mol Microbiol. 2006 May;60(3):749-64.

30.
31.

The role of the alarmone (p)ppGpp in sigma N competition for core RNA polymerase.

Laurie AD, Bernardo LM, Sze CC, Skarfstad E, Szalewska-Palasz A, Nyström T, Shingler V.

J Biol Chem. 2003 Jan 17;278(3):1494-503. Epub 2002 Nov 5.

32.

Regulation of sigma factor competition by the alarmone ppGpp.

Jishage M, Kvint K, Shingler V, Nyström T.

Genes Dev. 2002 May 15;16(10):1260-70.

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37.

Role of the DmpR-mediated regulatory circuit in bacterial biodegradation properties in methylphenol-amended soils.

Sarand I, Skärfstad E, Forsman M, Romantschuk M, Shingler V.

Appl Environ Microbiol. 2001 Jan;67(1):162-71.

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42.

Solution structure of phenol hydroxylase protein component P2 determined by NMR spectroscopy.

Qian H, Edlund U, Powlowski J, Shingler V, Sethson I.

Biochemistry. 1997 Jan 21;36(3):495-504.

PMID:
9012665
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46.

Signal sensing by sigma 54-dependent regulators: derepression as a control mechanism.

Shingler V.

Mol Microbiol. 1996 Feb;19(3):409-16. Review.

PMID:
8830233
48.

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