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Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner.

Gim E, Shim DW, Hwang I, Shin OS, Yu JW.

Immune Netw. 2019 Dec 23;19(6):e40. doi: 10.4110/in.2019.19.e40. eCollection 2019 Dec.


Aging and the Immune System: the Impact of Immunosenescence on Viral Infection, Immunity and Vaccine Immunogenicity.

Oh SJ, Lee JK, Shin OS.

Immune Netw. 2019 Nov 14;19(6):e37. doi: 10.4110/in.2019.19.e37. eCollection 2019 Dec. Review.


Recent Updates on Research Models and Tools to Study Virus-Host Interactions at the Placenta.

Lee JK, Oh SJ, Park H, Shin OS.

Viruses. 2019 Dec 18;12(1). pii: E5. doi: 10.3390/v12010005. Review.


Matrix Metalloproteinase-13 in Atherosclerotic Plaque Is Increased by Influenza A Virus Infection.

Lee HS, Noh JY, Shin OS, Song JY, Cheong HJ, Kim WJ.

J Infect Dis. 2020 Jan 2;221(2):256-266. doi: 10.1093/infdis/jiz580.


A Systems Vaccinology Approach Reveals the Mechanisms of Immunogenic Responses to Hantavax Vaccination in Humans.

Khan A, Shin OS, Na J, Kim JK, Seong RK, Park MS, Noh JY, Song JY, Cheong HJ, Park YH, Kim WJ.

Sci Rep. 2019 Mar 18;9(1):4760. doi: 10.1038/s41598-019-41205-1.


Advances in Zika Virusā»Host Cell Interaction: Current Knowledge and Future Perspectives.

Lee JK, Shin OS.

Int J Mol Sci. 2019 Mar 4;20(5). pii: E1101. doi: 10.3390/ijms20051101. Review.


Insights into ZIKV-Mediated Innate Immune Responses in Human Dermal Fibroblasts and Epidermal Keratinocytes.

Kim JA, Seong RK, Son SW, Shin OS.

J Invest Dermatol. 2019 Feb;139(2):391-399. doi: 10.1016/j.jid.2018.07.038. Epub 2018 Sep 12.


TLR4-mediated activation of the ERK pathway following UVA irradiation contributes to increased cytokine and MMP expression in senescent human dermal fibroblasts.

Seo SW, Park SK, Oh SJ, Shin OS.

PLoS One. 2018 Aug 17;13(8):e0202323. doi: 10.1371/journal.pone.0202323. eCollection 2018.


Analysis of IE62 mutations found in Varicella-Zoster virus vaccine strains for transactivation activity.

Ko H, Lee GM, Shin OS, Song MJ, Lee CH, Kim YE, Ahn JH.

J Microbiol. 2018 Jun;56(6):441-448. doi: 10.1007/s12275-018-8144-x. Epub 2018 Jun 1.


Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases.

Oh SJ, Choi YK, Shin OS.

Yonsei Med J. 2018 Mar;59(2):176-186. doi: 10.3349/ymj.2018.59.2.176. Review.


Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models.

Kim JA, Seong RK, Kumar M, Shin OS.

Viruses. 2018 Feb 9;10(2). pii: E72. doi: 10.3390/v10020072.


Vaccine-type mutations identified in Varicella zoster virus passaged in cell culture.

Kim SC, Won YH, Park JS, Jeon JS, Ahn JH, Song MJ, Shin OS, Lee CH.

Virus Res. 2018 Feb 2;245:62-68. doi: 10.1016/j.virusres.2017.12.004. Epub 2017 Dec 12.


Understanding the Pathogenesis of Zika Virus Infection Using Animal Models.

Krause KK, Azouz F, Shin OS, Kumar M.

Immune Netw. 2017 Oct;17(5):287-297. doi: 10.4110/in.2017.17.5.287. Epub 2017 Oct 19. Review.


Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophages.

Son S, Hwang I, Han SH, Shin JS, Shin OS, Yu JW.

J Biol Chem. 2017 Dec 15;292(50):20437-20448. doi: 10.1074/jbc.M117.806307. Epub 2017 Oct 19.


Invasive fungal infection (IFI) in pediatric leukemia: better outcome with ACT.

Shin OS.

Blood Res. 2017 Sep;52(3):151-152. doi: 10.5045/br.2017.52.3.151. Epub 2017 Sep 25. No abstract available.


Altered virulence of Highly Pathogenic Avian Influenza (HPAI) H5N8 reassortant viruses in mammalian models.

Park SJ, Kim EH, Kwon HI, Song MS, Kim SM, Kim YI, Si YJ, Lee IW, Nguyen HD, Shin OS, Kim CJ, Choi YK.

Virulence. 2018 Jan 1;9(1):133-148. doi: 10.1080/21505594.2017.1366408. Epub 2017 Sep 21.


Characterization and phylogenetic analysis of Varicella-zoster virus strains isolated from Korean patients.

Kim MH, Jeon JS, Kim IK, Park JS, Park H, Shin OS, Lee CH.

J Microbiol. 2017 Aug;55(8):665-672. doi: 10.1007/s12275-017-7171-3. Epub 2017 Jul 28.


Schlafen 14 (SLFN14) is a novel antiviral factor involved in the control of viral replication.

Seong RK, Seo SW, Kim JA, Fletcher SJ, Morgan NV, Kumar M, Choi YK, Shin OS.

Immunobiology. 2017 Nov;222(11):979-988. doi: 10.1016/j.imbio.2017.07.002. Epub 2017 Jul 11.


Humoral and Cellular Immunogenicity Induced by Avian Influenza A (H7N9) DNA Vaccine in Mice.

Choi EJ, Lee HS, Noh JY, Song JY, Cheong HJ, Shin OS, Lee H, Jeong M, Kim WJ.

Infect Chemother. 2017 Jun;49(2):117-122. doi: 10.3947/ic.2017.49.2.117.


STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways.

Kim JA, Park SK, Seo SW, Lee CH, Shin OS.

J Invest Dermatol. 2017 Oct;137(10):2101-2109. doi: 10.1016/j.jid.2017.03.041. Epub 2017 Jun 22.


Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner.

Yang J, Lee KM, Park S, Cho Y, Lee E, Park JH, Shin OS, Son J, Yoon SS, Yu JW.

Front Immunol. 2017 Mar 27;8:333. doi: 10.3389/fimmu.2017.00333. eCollection 2017.


Metformin alleviates ageing cellular phenotypes in Hutchinson-Gilford progeria syndrome dermal fibroblasts.

Park SK, Shin OS.

Exp Dermatol. 2017 Oct;26(10):889-895. doi: 10.1111/exd.13323. Epub 2017 May 3.


Enhanced Viral Replication by Cellular Replicative Senescence.

Kim JA, Seong RK, Shin OS.

Immune Netw. 2016 Oct;16(5):286-295. Epub 2016 Oct 25.


MDA7/IL-24 is an anti-viral factor that inhibits influenza virus replication.

Seong RK, Choi YK, Shin OS.

J Microbiol. 2016 Oct;54(10):695-700. doi: 10.1007/s12275-016-6383-2. Epub 2016 Sep 30.


Cross-protective efficacies of highly-pathogenic avian influenza H5N1 vaccines against a recent H5N8 virus.

Park SJ, Si YJ, Kim J, Song MS, Kim SM, Kim EH, Kwon HI, Kim YI, Lee OJ, Shin OS, Kim CJ, Shin EC, Choi YK.

Virology. 2016 Nov;498:36-43. doi: 10.1016/j.virol.2016.08.010. Epub 2016 Aug 17.


Analysis of single nucleotide polymorphism among Varicella-Zoster Virus and identification of vaccine-specific sites.

Jeon JS, Won YH, Kim IK, Ahn JH, Shin OS, Kim JH, Lee CH.

Virology. 2016 Sep;496:277-286. doi: 10.1016/j.virol.2016.06.017. Epub 2016 Jul 1.


Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway.

Park SK, Seong RK, Kim JA, Son SJ, Kim Y, Yokozawa T, Shin OS.

Nutr Res Pract. 2016 Feb;10(1):3-10. doi: 10.4162/nrp.2016.10.1.3. Epub 2016 Jan 8.


Erratum: Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice.

Park SJ, Kumar M, Kwon HI, Seong RK, Han K, Song JM, Kim CJ, Choi YK, Shin OS.

Sci Rep. 2016 Jan 29;6:20269. doi: 10.1038/srep20269. No abstract available.


Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice.

Park SJ, Kumar M, Kwon HI, Seong RK, Han K, Song JM, Kim CJ, Choi YK, Shin OS.

Sci Rep. 2015 Nov 18;5:16512. doi: 10.1038/srep16512. Erratum in: Sci Rep. 2016;6:20269.


Insights into the role of immunosenescence during varicella zoster virus infection (shingles) in the aging cell model.

Kim JA, Park SK, Kumar M, Lee CH, Shin OS.

Oncotarget. 2015 Nov 3;6(34):35324-43. doi: 10.18632/oncotarget.6117.


The herbal-derived honokiol and magnolol enhances immune response to infection with methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA).

Choi EJ, Kim HI, Kim JA, Jun SY, Kang SH, Park DJ, Son SJ, Kim Y, Shin OS.

Appl Microbiol Biotechnol. 2015 May;99(10):4387-96. doi: 10.1007/s00253-015-6382-y. Epub 2015 Jan 15.


In vitro and in vivo antimicrobial efficacy of natural plant-derived compounds against Vibrio cholerae of O1 El Tor Inaba serotype.

Kim HI, Kim JA, Choi EJ, Harris JB, Jeong SY, Son SJ, Kim Y, Shin OS.

Biosci Biotechnol Biochem. 2015;79(3):475-83. doi: 10.1080/09168451.2014.991685. Epub 2014 Dec 17.


Enhanced protection of pathogenic Escherichia coli ingested by a soil nematode Caenorhabditis elegans against sanitizer treatments.

Park MR, Oh S, Yun HS, Kim SH, Ko YH, Ryu JH, Rhee MS, Shin OS, Kim Y.

Biosci Biotechnol Biochem. 2014;78(11):1917-22. doi: 10.1080/09168451.2014.940830. Epub 2014 Jul 23.


Hantaviruses induce antiviral and pro-inflammatory innate immune responses in astrocytic cells and the brain.

Shin OS, Song GS, Kumar M, Yanagihara R, Lee HW, Song JW.

Viral Immunol. 2014 Aug;27(6):256-66. doi: 10.1089/vim.2014.0019. Epub 2014 Jun 17.


A novel adenovirus in Chinstrap penguins (Pygoscelis antarctica) in Antarctica.

Lee SY, Kim JH, Park YM, Shin OS, Kim H, Choi HG, Song JW.

Viruses. 2014 May 7;6(5):2052-61. doi: 10.3390/v6052052.


Muju virus, harbored by Myodes regulus in Korea, might represent a genetic variant of Puumala virus, the prototype arvicolid rodent-borne hantavirus.

Lee JG, Gu SH, Baek LJ, Shin OS, Park KS, Kim HC, Klein TA, Yanagihara R, Song JW.

Viruses. 2014 Apr 14;6(4):1701-14. doi: 10.3390/v6041701.


Whole-genome sequence of muju virus, an arvicolid rodent-borne hantavirus.

Lee JG, Gu SH, Baek LJ, Shin OS, Kim HC, Klein TA, Yanagihara R, Song JW.

Genome Announc. 2014 Feb 27;2(1). pii: e00099-14. doi: 10.1128/genomeA.00099-14.


Hantaviruses induce cell type- and viral species-specific host microRNA expression signatures.

Shin OS, Kumar M, Yanagihara R, Song JW.

Virology. 2013 Nov;446(1-2):217-24. doi: 10.1016/j.virol.2013.07.036. Epub 2013 Sep 2.


Natural selection in a bangladeshi population from the cholera-endemic ganges river delta.

Karlsson EK, Harris JB, Tabrizi S, Rahman A, Shlyakhter I, Patterson N, O'Dushlaine C, Schaffner SF, Gupta S, Chowdhury F, Sheikh A, Shin OS, Ellis C, Becker CE, Stuart LM, Calderwood SB, Ryan ET, Qadri F, Sabeti PC, Larocque RC.

Sci Transl Med. 2013 Jul 3;5(192):192ra86. doi: 10.1126/scitranslmed.3006338.


TRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferi.

Petnicki-Ocwieja T, Chung E, Acosta DI, Ramos LT, Shin OS, Ghosh S, Kobzik L, Li X, Hu LT.

Infect Immun. 2013 Feb;81(2):402-10. doi: 10.1128/IAI.00890-12. Epub 2012 Nov 19.


Distinct innate immune responses in human macrophages and endothelial cells infected with shrew-borne hantaviruses.

Shin OS, Yanagihara R, Song JW.

Virology. 2012 Dec 5;434(1):43-9. doi: 10.1016/j.virol.2012.08.004. Epub 2012 Sep 1.


LPLUNC1 modulates innate immune responses to Vibrio cholerae.

Shin OS, Uddin T, Citorik R, Wang JP, Della Pelle P, Kradin RL, Bingle CD, Bingle L, Camilli A, Bhuiyan TR, Shirin T, Ryan ET, Calderwood SB, Finberg RW, Qadri F, Larocque RC, Harris JB.

J Infect Dis. 2011 Nov;204(9):1349-57. doi: 10.1093/infdis/jir544. Epub 2011 Sep 7.


Innate immunity and transplantation tolerance: the potential role of TLRs/NLRs in GVHD.

Shin OS, Harris JB.

Korean J Hematol. 2011 Jun;46(2):69-79. doi: 10.5045/kjh.2011.46.2.69. Epub 2011 Jun 21.


Type III secretion is essential for the rapidly fatal diarrheal disease caused by non-O1, non-O139 Vibrio cholerae.

Shin OS, Tam VC, Suzuki M, Ritchie JM, Bronson RT, Waldor MK, Mekalanos JJ.

mBio. 2011 Jun 14;2(3):e00106-11. doi: 10.1128/mBio.00106-11. Print 2011.


Quorum sensing and a global regulator TsrA control expression of type VI secretion and virulence in Vibrio cholerae.

Zheng J, Shin OS, Cameron DE, Mekalanos JJ.

Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):21128-33. doi: 10.1073/pnas.1014998107. Epub 2010 Nov 17.


Downstream signals for MyD88-mediated phagocytosis of Borrelia burgdorferi can be initiated by TRIF and are dependent on PI3K.

Shin OS, Miller LS, Modlin RL, Akira S, Uematsu S, Hu LT.

J Immunol. 2009 Jul 1;183(1):491-8. doi: 10.4049/jimmunol.0900724.


Cardiovascular and respiratory changes in children during diagnostic laparoscopy and laparoscopic surgery.

Chung JH, Ahn KR, Shin OS, Kim CS, Kang KS, Yoo SH, Chung JW, Koo JU, Lee JS.

Korean J Anesthesiol. 2009 Jan;56(1):31-35. doi: 10.4097/kjae.2009.56.1.31.

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