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Impact of patient positioning uncertainty in noncoplanar intracranial stereotactic radiotherapy.

Tanaka Y, Oita M, Inomata S, Fuse T, Akino Y, Shimomura K.

J Appl Clin Med Phys. 2020 Jan 20. doi: 10.1002/acm2.12820. [Epub ahead of print]


Complementary double-stranded helical oligomers bearing achiral bifunctional groups that catalyze asymmetric aldol reaction.

Taura D, Shimomura K, Ousaka N, Yashima E.

Chirality. 2020 Jan 10. doi: 10.1002/chir.23169. [Epub ahead of print]


The Meniscus Tear: A Review of Stem Cell Therapies.

Jacob G, Shimomura K, Krych AJ, Nakamura N.

Cells. 2019 Dec 30;9(1). pii: E92. doi: 10.3390/cells9010092. Review.


Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.

Gonda K, Akama T, Nakamura T, Hashimoto E, Kyoya N, Rokkaku Y, Maejima Y, Horita S, Tachibana K, Abe N, Ohtake T, Shimomura K, Kono K, Saji S, Takenoshita S, Higashihara E.

J Med Case Rep. 2019 Dec 24;13(1):381. doi: 10.1186/s13256-019-2274-6.


The hypothalamus to brainstem circuit suppresses late-onset body weight gain.

Maejima Y, Kato S, Horita S, Ueta Y, Takenoshita S, Kobayashi K, Shimomura K.

Sci Rep. 2019 Dec 4;9(1):18360. doi: 10.1038/s41598-019-54870-z.


Overactivation of Akt Contributes to MEK Inhibitor Primary and Acquired Resistance in Colorectal Cancer Cells.

Tsubaki M, Takeda T, Noguchi M, Jinushi M, Seki S, Morii Y, Shimomura K, Imano M, Satou T, Nishida S.

Cancers (Basel). 2019 Nov 25;11(12). pii: E1866. doi: 10.3390/cancers11121866.


Association between cognitive impairment patient with solid cancer and insulin resistance.

Gonda K, Yaginuma K, Rokkaku Y, Horita S, Maejima Y, Shimomura K.

BMC Res Notes. 2019 Oct 28;12(1):705. doi: 10.1186/s13104-019-4739-5.


Comparison of patient-specific intensity modulated radiation therapy quality assurance for the prostate across multiple institutions.

Kubo K, Monzen H, Shimomura K, Matsumoto K, Sato T, Tamura M, Nakamatsu K, Ishii K, Kawamorita R.

Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):600-605. doi: 10.1016/j.rpor.2019.09.009. Epub 2019 Oct 17.


The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma.

Jojima T, Wakamatsu S, Kase M, Iijima T, Maejima Y, Shimomura K, Kogai T, Tomaru T, Usui I, Aso Y.

Int J Mol Sci. 2019 Oct 22;20(20). pii: E5237. doi: 10.3390/ijms20205237.


The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats.

Maejima Y, Yokota S, Horita S, Shimomura K.

Sci Rep. 2019 Aug 14;9(1):11848. doi: 10.1038/s41598-019-48336-5.


Comparative Clinical Outcomes After Intra-articular Injection With Adipose-Derived Cultured Stem Cells or Noncultured Stromal Vascular Fraction for the Treatment of Knee Osteoarthritis.

Yokota N, Hattori M, Ohtsuru T, Otsuji M, Lyman S, Shimomura K, Nakamura N.

Am J Sports Med. 2019 Sep;47(11):2577-2583. doi: 10.1177/0363546519864359. Epub 2019 Aug 2.


Genetics of Circadian Rhythms.

Vitaterna MH, Shimomura K, Jiang P.

Neurol Clin. 2019 Aug;37(3):487-504. doi: 10.1016/j.ncl.2019.05.002. Epub 2019 May 29. Review.


An In Vitro System for Evaluating Molecular Targeted Drugs Using Lung Patient-Derived Tumor Organoids.

Takahashi N, Hoshi H, Higa A, Hiyama G, Tamura H, Ogawa M, Takagi K, Goda K, Okabe N, Muto S, Suzuki H, Shimomura K, Watanabe S, Takagi M.

Cells. 2019 May 20;8(5). pii: E481. doi: 10.3390/cells8050481.


Is curative gastrectomy justified for gastric cancer with cytology positive as the only stage IV factor?

Komatsu S, Shioaki Y, Furuke H, Ohta A, Tsuji R, Tanaka S, Kumano T, Imura KI, Shimomura K, Ikeda J, Taniguchi F, Ueshima Y, Lee CJ, Deguchi E, Ikeda E, Otsuji E.

Langenbecks Arch Surg. 2019 Aug;404(5):599-604. doi: 10.1007/s00423-019-01791-0. Epub 2019 May 9.


Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect.

Lin H, Beck AM, Shimomura K, Sohn J, Fritch MR, Deng Y, Kilroy EJ, Tang Y, Alexander PG, Tuan RS.

J Tissue Eng Regen Med. 2019 Aug;13(8):1418-1429. doi: 10.1002/term.2883. Epub 2019 Jun 19.


MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years.

Momma T, Gonda K, Akama Y, Endo E, Ujiie D, Fujita S, Maejima Y, Horita S, Shimomura K, Saji S, Kono K, Yashima R, Watanabe F, Sugano K, Nomizu T.

BMC Med Genet. 2019 May 2;20(1):67. doi: 10.1186/s12881-019-0792-0.


Noninvasive continuous blood pressure monitoring using microelectromechanical system technology.

Satake S, Shimura T, Ono T, Shimomura K, Takenoshita S, Kono K.

Blood Press Monit. 2019 Jun;24(3):155-159. doi: 10.1097/MBP.0000000000000380.


LGR4 is essential for R-spondin1-mediated suppression of food intake via pro-opiomelanocortin.

Otsuka A, Jinguji A, Maejima Y, Kasahara Y, Shimomura K, Hidema S, Nishimori K.

Biosci Biotechnol Biochem. 2019 Jul;83(7):1336-1342. doi: 10.1080/09168451.2019.1591266. Epub 2019 Mar 27.


[Validation of the 8th Edition of the UICC TNM Classification for Stage Ⅲ Gastric Cancer].

Tanaka S, Komatsu S, Ohta A, Furuke H, Kumano T, Imura K, Shimomura K, Ikeda J, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2019 Mar;46(3):502-504. Japanese.


Impact of dapagliflozin, an SGLT2 inhibitor, on serum levels of soluble dipeptidyl peptidase-4 in patients with type 2 diabetes and non-alcoholic fatty liver disease.

Aso Y, Kato K, Sakurai S, Kishi H, Shimizu M, Jojima T, Iijima T, Maejima Y, Shimomura K, Usui I.

Int J Clin Pract. 2019 May;73(5):e13335. doi: 10.1111/ijcp.13335. Epub 2019 Apr 1.


[Development of Novel Immobilization Adapter for Head and Neck Radiotherapy with Low-attenuation Material].

Matsumoto K, Saika T, Shimomura K, Hanaoka K, Tamura M, Monzen H, Hayakawa M, Okumura M.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2019;75(2):167-173. doi: 10.6009/jjrt.2019_JSRT_75.2.167. Japanese.


[Laparoscopy and Endoscopy Cooperative Surgery(LECS)-Assisted Open Partial Gastrectomy for a High-Risk Gastrointestinal Stromal Tumor].

Tsuji R, Komatsu S, Kumano T, Ohta A, Furuke H, Tanaka S, Imura K, Shimomura K, Ikeda J, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2019 Jan;46(1):172-174. Japanese.


[A Case of GIST with Extensive Peritoneal Dissemination Controlled over Long-Term by Low-Dose, Intermittent Administration of Imatinib after Weight Loss Surgery].

Nanishi K, Taniguchi F, Mizuno A, Furuke H, Tanaka S, Kumano T, Komatsu S, Imura K, Shimomura K, Ikeda J, Takashina K, Shioaki Y, Ikeda E.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2348-2350. Japanese.


[Better Effects of Inventive Nutritional Approaches for Chemotherapy and Conversion Surgery in Stage Ⅳ Gastric Cancer].

Uebayashi A, Komatsu S, Tsuji R, Ohta A, Tanaka S, Kumano T, Imura K, Shimomura K, Ikeda J, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2255-2257. Japanese.


[Modified NEWS as a Safe and Inventive Approach for Gastrointestinal Stromal Tumor near the Esophagogastric Junction].

Tsukuda N, Komatsu S, Kumano T, Matsumuro Y, Ohta A, Tsuji R, Minowa K, Tanaka S, Imura K, Shimomura K, Ikeda J, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2153-2155. Japanese.


[Surgical Technique for Lesser Curvature Lymph Node Dissection in Laparoscopic Distal Gastrectomy].

Kumano T, Komatsu S, Furuke H, Tanaka S, Imura K, Shimomura K, Ikeda J, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2018 Dec;45(13):2057-2059. Japanese.


Three-dimensional iterative multislice reconstruction for ptychographic X-ray computed tomography.

Shimomura K, Hirose M, Higashino T, Takahashi Y.

Opt Express. 2018 Nov 26;26(24):31199-31208. doi: 10.1364/OE.26.031199.


Enhanced repair of meniscal hoop structure injuries using an aligned electrospun nanofibrous scaffold combined with a mesenchymal stem cell-derived tissue engineered construct.

Shimomura K, Rothrauff BB, Hart DA, Hamamoto S, Kobayashi M, Yoshikawa H, Tuan RS, Nakamura N.

Biomaterials. 2019 Feb;192:346-354. doi: 10.1016/j.biomaterials.2018.11.009. Epub 2018 Nov 13.


Structural basis of different substrate preferences of two old yellow enzymes from yeasts in the asymmetric reduction of enone compounds.

Horita S, Kataoka M, Kitamura N, Miyakawa T, Ohtsuka J, Maejima Y, Shimomura K, Nagata K, Shimizu S, Tanokura M.

Biosci Biotechnol Biochem. 2019 Mar;83(3):456-462. doi: 10.1080/09168451.2018.1543014. Epub 2018 Nov 16.


Human Synovial MSC Good Manufacturing Practices for Articular Cartilage Regeneration.

Fernandes TL, Kimura HA, Pinheiro CCG, Shimomura K, Nakamura N, Ferreira JRM, Gomoll AH, Hernandez AJ, Bueno DF.

Tissue Eng Part C Methods. 2018 Nov 9. doi: 10.1089/ten.TEC.2018.0219. [Epub ahead of print]


Excitability of oxytocin neurons in paraventricular nucleus is regulated by voltage-gated potassium channels Kv4.2 and Kv4.3.

Imai R, Yokota S, Horita S, Ueta Y, Maejima Y, Shimomura K.

Biosci Biotechnol Biochem. 2019 Feb;83(2):202-211. doi: 10.1080/09168451.2018.1537773. Epub 2018 Nov 4.


Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report.

Gonda K, Tachiya Y, Hatakeyama Y, Momma T, Tamaoki T, Maejima Y, Rokkaku Y, Saji S, Shimomura K, Kono K.

J Med Case Rep. 2018 Oct 26;12(1):312. doi: 10.1186/s13256-018-1823-8.


A Prospective Trial Evaluating the Safety of a Shortened Infusion of Ramucirumab in Patients with Gastrointestinal Cancer.

Hashimoto N, Mitani S, Taniguchi H, Narita Y, Kato K, Masuishi T, Kadowaki S, Onishi S, Tajika M, Takahashi S, Shimomura K, Takahata C, Hotta E, Kobara M, Muro K.

Oncologist. 2019 Feb;24(2):159-e66. doi: 10.1634/theoncologist.2018-0580. Epub 2018 Oct 10.


The effect of avertin anesthesia and a mixture of three types of anesthetic agents on food intakeand body weight in high fat-induced obese maleand female mice.

Maejima Y, Yokota S, O'Hashi R, Aoyama M, Shimomura K.

Exp Anim. 2019 Feb 26;68(1):57-69. doi: 10.1538/expanim.17-0145. Epub 2018 Sep 13.


Meniscal repair and regeneration: Current strategies and future perspectives.

Shimomura K, Hamamoto S, Hart DA, Yoshikawa H, Nakamura N.

J Clin Orthop Trauma. 2018 Jul-Sep;9(3):247-253. doi: 10.1016/j.jcot.2018.07.008. Epub 2018 Jul 17. Review.


Low Infection of Phelipanche aegyptiaca in Micro-Tom Mutants Deficient in CAROTENOIDCLEAVAGE DIOXYGENASE 8.

Hasegawa S, Tsutsumi T, Fukushima S, Okabe Y, Saito J, Katayama M, Shindo M, Yamada Y, Shimomura K, Yoneyama K, Akiyama K, Aoki K, Ariizumi T, Ezura H, Yamaguchi S, Umehara M.

Int J Mol Sci. 2018 Sep 6;19(9). pii: E2645. doi: 10.3390/ijms19092645.


Nuclear Magnetic Field in Solids Detected with Negative-Muon Spin Rotation and Relaxation.

Sugiyama J, Umegaki I, Nozaki H, Higemoto W, Hamada K, Takeshita S, Koda A, Shimomura K, Ninomiya K, Kubo MK.

Phys Rev Lett. 2018 Aug 24;121(8):087202. doi: 10.1103/PhysRevLett.121.087202.


Reciprocity and exclusion in informal financial institutions: An experimental study of rotating savings and credit associations.

Koike S, Nakamaru M, Otaka T, Shimao H, Shimomura KI, Yamato T.

PLoS One. 2018 Aug 29;13(8):e0202878. doi: 10.1371/journal.pone.0202878. eCollection 2018.


Memantine has no effect on KATP channels in pancreatic β cells.

Imai R, Misaka S, Horita S, Yokota S, O'hashi R, Maejima Y, Shimomura K.

BMC Res Notes. 2018 Aug 25;11(1):614. doi: 10.1186/s13104-018-3715-9.


First-in-Human Pilot Study of Implantation of a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stem Cells for Repair of Knee Chondral Lesions.

Shimomura K, Yasui Y, Koizumi K, Chijimatsu R, Hart DA, Yonetani Y, Ando W, Nishii T, Kanamoto T, Horibe S, Yoshikawa H, Nakamura N, Sakaue M, Sugita N, Moriguchi Y.

Am J Sports Med. 2018 Aug;46(10):2384-2393. doi: 10.1177/0363546518781825. Epub 2018 Jul 3.


Similar effect of quercetin on CYP2E1 and CYP2C9 activities in humans?

Misaka S, Shimomura K.

Eur J Clin Pharmacol. 2018 Sep;74(9):1187-1188. doi: 10.1007/s00228-018-2479-4. Epub 2018 May 17. No abstract available.


Development of a Novel Large Animal Model to Evaluate Human Dental Pulp Stem Cells for Articular Cartilage Treatment.

Fernandes TL, Shimomura K, Asperti A, Pinheiro CCG, Caetano HVA, Oliveira CRGCM, Nakamura N, Hernandez AJ, Bueno DF.

Stem Cell Rev Rep. 2018 Oct;14(5):734-743. doi: 10.1007/s12015-018-9820-2.


Update of green tea interactions with cardiovascular drugs and putative mechanisms.

Werba JP, Misaka S, Giroli MG, Shimomura K, Amato M, Simonelli N, Vigo L, Tremoli E.

J Food Drug Anal. 2018 Apr;26(2S):S72-S77. doi: 10.1016/j.jfda.2018.01.008. Epub 2018 Feb 14. Review.


The Anorexigenic Neural Pathways of Oxytocin and Their Clinical Implication.

Maejima Y, Yokota S, Nishimori K, Shimomura K.

Neuroendocrinology. 2018;107(1):91-104. doi: 10.1159/000489263. Epub 2018 Apr 16. Review.


[Evaluated Cases of Anastomotic Recurrence in Colorectal Cancer].

Ikeda J, Furuke H, Kato C, Takabatake K, Kishimoto T, Kumano T, Imura K, Shimomura K, Kubota T, Taniguchi F, Shioaki Y.

Gan To Kagaku Ryoho. 2018 Apr;45(4):706-708. Japanese.


Upregulation of DWARF27 is associated with increased strigolactone levels under sulfur deficiency in rice.

Shindo M, Shimomura K, Yamaguchi S, Umehara M.

Plant Direct. 2018 Apr 11;2(4):e00050. doi: 10.1002/pld3.50. eCollection 2018 Apr.


Quantification of Endogenous Auxin and Cytokinin During Internode Culture of Ipecac.

Koike I, Shimomura K, Umehara M.

J Vis Exp. 2018 Mar 15;(133). doi: 10.3791/56902.


MexEF-OprN multidrug efflux pump transporter negatively controls N-acyl-homoserine lactone accumulation in pseudomonas syringae pv. Tabaci 6605.

Sawada T, Eguchi M, Asaki S, Kashiwagi R, Shimomura K, Taguchi F, Matsui H, Yamamoto M, Noutoshi Y, Toyoda K, Ichinose Y.

Mol Genet Genomics. 2018 Aug;293(4):907-917. doi: 10.1007/s00438-018-1430-9. Epub 2018 Mar 16.


Self-expandable Metallic Stents Contribute to Reducing Perioperative Complications in Colorectal Cancer Patients with Acute Obstruction.

Furuke H, Komatsu S, Ikeda J, Tanaka S, Kumano T, Imura KI, Shimomura K, Taniguchi F, Ueshima Y, Takashina KI, Lee CJ, Deguchi E, Ikeda E, Otsuji E, Shioaki Y.

Anticancer Res. 2018 Mar;38(3):1749-1753.


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