Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 555

1.

Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: results from the global DISCOVER study programme.

Nicolucci A, Charbonnel B, Gomes MB, Khunti K, Kosiborod M, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Razufa J, Fenici P, Hammar N, Surmont F, Tang F, Pocock S.

Diabetes Obes Metab. 2019 Jul 12. doi: 10.1111/dom.13830. [Epub ahead of print]

PMID:
31297947
2.

Glucocorticoid replacement affects serum adiponectin levels and HDL-C in patients with secondary adrenal insufficiency.

Hayashi R, Tamada D, Murata M, Kitamura T, Mukai K, Maeda N, Otsuki M, Shimomura I.

J Clin Endocrinol Metab. 2019 Jul 10. pii: jc.2019-00420. doi: 10.1210/jc.2019-00420. [Epub ahead of print]

PMID:
31290981
3.

Single-cell Analysis Reveals a Preexisting Drug-Resistant Subpopulation in the Luminal Breast Cancer Subtype.

Prieto-Vila M, Usuba W, Takahashi RU, Shimomura I, Sasaki H, Ochiya T, Yamamoto Y.

Cancer Res. 2019 Jul 9. pii: canres.0122.2019. doi: 10.1158/0008-5472.CAN-19-0122. [Epub ahead of print]

PMID:
31289135
4.

Population Approaches Targeting Metabolic Syndrome Focusing on Japanese Trials.

Nishizawa H, Shimomura I.

Nutrients. 2019 Jun 25;11(6). pii: E1430. doi: 10.3390/nu11061430.

5.

Pancreatic fat is related to the longitudinal decrease in the increment of C-peptide in glucagon stimulation test in type 2 diabetes patients.

Ishibashi C, Kozawa J, Hosakawa Y, Yoneda S, Kimura T, Fujita Y, Fukui K, Iwahashi H, Shimomura I.

J Diabetes Investig. 2019 Jun 25. doi: 10.1111/jdi.13108. [Epub ahead of print]

6.

Positive correlation between fasting plasma glucagon and serum C-peptide in Japanese patients with diabetes.

Hosokawa Y, Kozawa J, Nishizawa H, Kawamori D, Maeda N, Otsuki M, Matsuoka TA, Iwahashi H, Shimomura I.

Heliyon. 2019 May 13;5(5):e01715. doi: 10.1016/j.heliyon.2019.e01715. eCollection 2019 May.

7.

Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts.

Naito Y, Yamamoto Y, Sakamoto N, Shimomura I, Kogure A, Kumazaki M, Yokoi A, Yashiro M, Kiyono T, Yanagihara K, Takahashi RU, Hirakawa K, Yasui W, Ochiya T.

Oncogene. 2019 Jul;38(28):5566-5579. doi: 10.1038/s41388-019-0832-4. Epub 2019 May 30.

PMID:
31147602
8.

T-Lymphocyte Infiltration to Islets in the Pancreas of a Patient Who Developed Type 1 Diabetes After Administration of Immune Checkpoint Inhibitors.

Yoneda S, Imagawa A, Hosokawa Y, Baden MY, Kimura T, Uno S, Fukui K, Goto K, Uemura M, Eguchi H, Iwahashi H, Kozawa J, Shimomura I.

Diabetes Care. 2019 Jul;42(7):e116-e118. doi: 10.2337/dc18-2518. Epub 2019 May 10. No abstract available.

PMID:
31076419
9.

Study Profile: Japan Trial in High-risk Individuals to Accelerate their Referral to Physicians (J-HARP) - a Nurse-led, Community-based Prevention Program of Lifestyle-related Disease.

Noguchi M, Kojima S, Sairenchi T, Kinuta M, Yamakawa M, Nishizawa H, Takahara M, Imano H, Kitamura A, Yoshida T, Shintani A, Saito I, Yokoyama T, Shimomura I, Iso H.

J Epidemiol. 2019 Apr 13. doi: 10.2188/jea.JE20180194. [Epub ahead of print]

10.

Treatment of type 2 diabetes mellitus worldwide: Baseline patient characteristics in the global DISCOVER study.

Gomes MB, Rathmann W, Charbonnel B, Khunti K, Kosiborod M, Nicolucci A, Pocock SJ, Shestakova MV, Shimomura I, Tang F, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Ji L; DISCOVER investigators.

Diabetes Res Clin Pract. 2019 May;151:20-32. doi: 10.1016/j.diabres.2019.03.024. Epub 2019 Mar 20.

11.

Pioglitazone strengthen therapeutic effect of adipose-derived regenerative cells against ischemic cardiomyopathy through enhanced expression of adiponectin and modulation of macrophage phenotype.

Mori D, Miyagawa S, Matsuura R, Sougawa N, Fukushima S, Ueno T, Toda K, Kuratani T, Tomita K, Maeda N, Shimomura I, Sawa Y.

Cardiovasc Diabetol. 2019 Mar 22;18(1):39. doi: 10.1186/s12933-019-0829-x.

12.

Clinical utility of carotid ultrasonography: Application for the management of patients with diabetes.

Katakami N, Matsuoka TA, Shimomura I.

J Diabetes Investig. 2019 Mar 18. doi: 10.1111/jdi.13042. [Epub ahead of print] Review.

13.

Synthetic Lethality in Lung Cancer-From the Perspective of Cancer Genomics.

Shimomura I, Yamamoto Y, Ochiya T.

Medicines (Basel). 2019 Mar 12;6(1). pii: E38. doi: 10.3390/medicines6010038. Review.

14.

Intractable Coronary Artery Disease in a Patient With Type 2 Diabetes Presenting With Triglyceride Deposit Cardiomyovasculopathy.

Kozawa J, Higashi M, Shimomura I, Hirano KI.

Diabetes Care. 2019 May;42(5):983-986. doi: 10.2337/dc18-2365. Epub 2019 Mar 12. No abstract available.

PMID:
30862655
15.

Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancer.

Shimomura I, Yokoi A, Kohama I, Kumazaki M, Tada Y, Tatsumi K, Ochiya T, Yamamoto Y.

Cancer Lett. 2019 Jun 1;451:11-22. doi: 10.1016/j.canlet.2019.03.002. Epub 2019 Mar 9.

PMID:
30862488
16.

The number of positive confirmatory tests is associated with the clinical presentation and incidence of cardiovascular and cerebrovascular events in primary aldosteronism.

Saiki A, Tamada D, Hayashi R, Mukai K, Kitamura T, Takahara M, Otsuki M, Shimomura I.

Hypertens Res. 2019 Mar 8. doi: 10.1038/s41440-019-0247-1. [Epub ahead of print]

PMID:
30850754
17.

Adipocyte GR Inhibits Healthy Adipose Expansion Through Multiple Mechanisms in Cushing Syndrome.

Hayashi R, Okuno Y, Mukai K, Kitamura T, Hayakawa T, Onodera T, Murata M, Fukuhara A, Imamura R, Miyagawa Y, Nonomura N, Otsuki M, Shimomura I.

Endocrinology. 2019 Mar 1;160(3):504-521. doi: 10.1210/en.2018-01029.

PMID:
30649271
18.

Adiponectin promotes muscle regeneration through binding to T-cadherin.

Tanaka Y, Kita S, Nishizawa H, Fukuda S, Fujishima Y, Obata Y, Nagao H, Masuda S, Nakamura Y, Shimizu Y, Mineo R, Natsukawa T, Funahashi T, Ranscht B, Fukada SI, Maeda N, Shimomura I.

Sci Rep. 2019 Jan 9;9(1):16. doi: 10.1038/s41598-018-37115-3.

19.

Diffusion-weighted magnetic resonance imaging in the pancreas of fulminant type 1 diabetes.

Tokunaga A, Imagawa A, Nishio H, Hayata S, Shimomura I, Abiru N, Awata T, Ikegami H, Uchigata Y, Oikawa Y, Osawa H, Kajio H, Kawasaki E, Kawabata Y, Kozawa J, Shimada A, Takahashi K, Tanaka S, Chujo D, Fukui T, Miura J, Yasuda K, Yasuda H, Kobayashi T, Hanafusa T; consultation of Japan Diabetes Society Committee on Fulminant Type 1 Diabetes Mellitus Research.

Diabetol Int. 2018 Apr 12;9(4):257-265. doi: 10.1007/s13340-018-0355-1. eCollection 2018 Oct.

20.

Mucosa-associated lymphoid tissue lymphoma with metachronous involvement of the palpebral conjunctiva and bronchus: A case report.

Shimomura I, Miki Y, Suzuki E, Katsumata M, Hashimoto D, Arai Y, Otsuki Y, Nakamura H.

Respir Med Case Rep. 2018 Dec 8;26:101-104. doi: 10.1016/j.rmcr.2018.12.004. eCollection 2019.

21.

Suppression Failure of Cortisol Secretion by Dexamethasone May Occur in Glucagon-like Peptide-1 Receptor Agonist-treated Patients with Diabetic Autonomic Neuropathy.

Nagai Y, Mukai K, Otsuki M, Kimura T, Kozawa J, Nishizawa H, Maeda N, Matsuoka TA, Iwahashi H, Imagawa A, Shimomura I.

Intern Med. 2019 Apr 1;58(7):949-953. doi: 10.2169/internalmedicine.1585-18. Epub 2018 Dec 18.

22.

Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis.

Shimomura I, Abe M, Li Y, Tsushima K, Sakao S, Tanabe N, Ikusaka M, Tatsumi K.

Intern Med. 2019 Apr 1;58(7):965-968. doi: 10.2169/internalmedicine.1384-18. Epub 2018 Dec 18.

23.

Metabolomic Analysis of Diet-Induced Obese Mice Supplemented with Eicosapentaenoic Acid.

Nishitani S, Fukuhara A, Jinno Y, Kawano H, Yano T, Otsuki M, Shimomura I.

Exp Clin Endocrinol Diabetes. 2018 Dec 10. doi: 10.1055/a-0802-9064. [Epub ahead of print]

PMID:
30536265
24.

Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program).

Kosiborod M, Gomes MB, Nicolucci A, Pocock S, Rathmann W, Shestakova MV, Watada H, Shimomura I, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Tang F, Khunti K; DISCOVER investigators.

Cardiovasc Diabetol. 2018 Nov 28;17(1):150. doi: 10.1186/s12933-018-0787-8.

25.

Clinical Characteristics of Acromegalic Patients With Paradoxical GH Response to Oral Glucose Load.

Mukai K, Otsuki M, Tamada D, Kitamura T, Hayashi R, Saiki A, Goto Y, Arita H, Oshino S, Morii E, Saitoh Y, Shimomura I.

J Clin Endocrinol Metab. 2019 May 1;104(5):1637-1644. doi: 10.1210/jc.2018-00975.

PMID:
30476255
26.

Impact of glycosylphosphatidylinositol-specific phospholipase D on hepatic diacylglycerol accumulation, steatosis, and insulin resistance in diet-induced obesity.

Masuda S, Fujishima Y, Maeda N, Tsugawa-Shimizu Y, Nakamura Y, Tanaka Y, Obata Y, Fukuda S, Nagao H, Kita S, Nishizawa H, Shimomura I.

Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E239-E250. doi: 10.1152/ajpendo.00319.2018. Epub 2018 Nov 20.

PMID:
30457913
27.

Evaluation of health utility values for diabetic complications, treatment regimens, glycemic control and other subjective symptoms in diabetic patients using the EQ-5D-5L.

Takahara M, Katakami N, Shiraiwa T, Abe K, Ayame H, Ishimaru Y, Iwamoto M, Shimizu M, Tomonaga O, Yokoyama H, Matsuoka TA, Shimomura I.

Acta Diabetol. 2019 Mar;56(3):309-319. doi: 10.1007/s00592-018-1244-6. Epub 2018 Oct 23.

PMID:
30353354
28.

Evaluation of Hypothalamic-Pituitary-Adrenal Axis by the GHRP2 Test: Comparison With the Insulin Tolerance Test.

Hayakawa T, Kitamura T, Tamada D, Mukai K, Hayashi R, Takahara M, Otsuki M, Shimomura I.

J Endocr Soc. 2018 Jun 26;2(8):860-869. doi: 10.1210/js.2018-00102. eCollection 2018 Aug 1.

29.

Impact of MR on mature adipocytes in high-fat/high-sucrose diet-induced obesity

Hayakawa T, Minemura T, Onodera T, Shin J, Okuno Y, Fukuhara A, Otsuki M, Shimomura I.

J Endocrinol. 2018 Oct 1;239(1):63–71. doi: 10.1530/JOE-18-0026.

PMID:
30307154
30.

Different daily glycemic profiles after switching from once-daily alogliptin plus twice-daily metformin to their once-daily fixed-dose combination in Japanese type 2 diabetic patients.

Takahara M, Shiraiwa T, Katakami N, Maeno Y, Yamamoto K, Shiraiwa Y, Yoshida Y, Matsuoka TA, Shimomura I.

Endocr J. 2019 Jan 28;66(1):11-17. doi: 10.1507/endocrj.EJ18-0313. Epub 2018 Oct 11.

31.

Fat cell lipolysis and future weight gain.

Nishizawa H, Shimomura I.

J Diabetes Investig. 2019 Mar;10(2):221-223. doi: 10.1111/jdi.12950. Epub 2018 Nov 13. No abstract available.

32.

Case of a novel PAX6 mutation with aniridia and insulin-dependent diabetes mellitus.

Motoda S, Fujita S, Kozawa J, Kimura T, Fukui K, Ikuno Y, Imagawa A, Iwahashi H, Shimomura I.

J Diabetes Investig. 2019 Mar;10(2):552-553. doi: 10.1111/jdi.12902. Epub 2018 Aug 27.

33.

Skin autofluorescence is associated with vascular complications in patients with type 2 diabetes.

Osawa S, Katakami N, Sato I, Ninomiya H, Omori K, Yamamoto Y, Takahara M, Miyashita K, Sakamoto F, Kawamori D, Matsuoka T, Shimomura I.

J Diabetes Complications. 2018 Sep;32(9):839-844. doi: 10.1016/j.jdiacomp.2018.06.009. Epub 2018 Jun 22.

PMID:
30099985
34.

Low muscle quality in Japanese type 2 diabetic patients with visceral fat accumulation.

Murai J, Nishizawa H, Otsuka A, Fukuda S, Tanaka Y, Nagao H, Sakai Y, Suzuki M, Yokota S, Tada H, Doi M, Fujishima Y, Kita S, Funahashi T, Maeda N, Nakamura T, Shimomura I.

Cardiovasc Diabetol. 2018 Aug 4;17(1):112. doi: 10.1186/s12933-018-0755-3.

35.

Identification of Metabolites Associated with Onset of CAD in Diabetic Patients Using CE-MS Analysis: A Pilot Study.

Omori K, Katakami N, Yamamoto Y, Ninomiya H, Takahara M, Matsuoka TA, Bamba T, Fukusaki E, Shimomura I.

J Atheroscler Thromb. 2019 Mar 1;26(3):233-245. doi: 10.5551/jat.42945. Epub 2018 Aug 1.

36.

Impact of MR on mature adipocytes in high-fat/high-sucrose diet-induced obesity.

Hayakawa T, Minemura T, Onodera T, Shin J, Okuno Y, Fukuhara A, Otsuki M, Shimomura I.

J Endocrinol. 2018 Jul 26. pii: JOE-18-0026. doi: 10.1530/JOE-18-0026. [Epub ahead of print]

PMID:
30049823
37.

Factors associated with treatment satisfaction in patients with type 2 diabetes mellitus using oral glucose-lowering agents: a cross-sectional study in urban districts in Japan.

Hayashi I, Watanabe N, Nakata S, Komatsu R, Motoda S, Fujita Y, Ishibashi C, Yamaguchi Baden M, Kimura T, Takahara M, Kozawa J, Imagawa A, Iwahashi H, Shimomura I.

Endocr J. 2018 Oct 29;65(10):1001-1009. doi: 10.1507/endocrj.EJ18-0182. Epub 2018 Jul 20.

38.

Glucose Intolerance After Pancreatectomy Was Associated With Preoperative Hemoglobin A1c, Insulin Resistance, and Histological Pancreatic Fatty Infiltration.

Ishibashi C, Kozawa J, Fujita Y, Yoneda S, Uno S, Kimura T, Fukui K, Nojima S, Morii E, Eguchi H, Iwahashi H, Imagawa A, Shimomura I.

Pancreas. 2018 Sep;47(8):e48-e50. doi: 10.1097/MPA.0000000000001109. No abstract available.

39.

Association between Subclinical Atherosclerosis Markers and the Level of Accumulated Advanced Glycation End-Products in the Skin of Patients with Diabetes.

Ninomiya H, Katakami N, Sato I, Osawa S, Yamamoto Y, Takahara M, Kawamori D, Matsuoka TA, Shimomura I.

J Atheroscler Thromb. 2018 Dec 1;25(12):1274-1284. doi: 10.5551/jat.44859. Epub 2018 Jun 30.

40.

TSH ratio as a novel diagnostic method for Cushing's syndrome.

Tamada D, Kitamura T, Takahara M, Tanaka T, Takeda M, Otsuki M, Shimomura I.

Endocr J. 2018 Aug 27;65(8):841-848. doi: 10.1507/endocrj.EJ18-0101. Epub 2018 Jun 19. Erratum in: Endocr J. 2018;65(9):969.

41.

Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytes.

Nishitani S, Fukuhara A, Shin J, Okuno Y, Otsuki M, Shimomura I.

Sci Rep. 2018 Jun 11;8(1):8805. doi: 10.1038/s41598-018-27181-y.

42.

Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia.

Nagao H, Nishizawa H, Tanaka Y, Fukata T, Mizushima T, Furuno M, Bamba T, Tsushima Y, Fujishima Y, Kita S, Funahashi T, Maeda N, Mori M, Fukusaki E, Shimomura I.

Obesity (Silver Spring). 2018 Jul;26(7):1168-1178. doi: 10.1002/oby.22202. Epub 2018 Jun 7.

43.

Dysregulated plasma glucagon levels in Japanese young adult type 1 diabetes patients.

Kawamori D, Katakami N, Takahara M, Miyashita K, Sakamoto F, Yasuda T, Matsuoka TA, Shimomura I.

J Diabetes Investig. 2019 Jan;10(1):62-66. doi: 10.1111/jdi.12862. Epub 2018 Jun 7.

44.

Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.

Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, Fujishima Y, Nagao H, Masuda S, Tanaka Y, Nakamura Y, Nishizawa H, Funahashi T, Ranscht B, Izumi Y, Bamba T, Fukusaki E, Hanayama R, Shimada S, Maeda N, Shimomura I.

JCI Insight. 2018 Apr 19;3(8). pii: 99680. doi: 10.1172/jci.insight.99680. eCollection 2018 Apr 19.

45.

Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway.

Okuno Y, Fukuhara A, Hashimoto E, Kobayashi H, Kobayashi S, Otsuki M, Shimomura I.

Diabetes. 2018 Jun;67(6):1113-1127. doi: 10.2337/db17-1032. Epub 2018 Apr 4.

46.

SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes.

Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, Shimomura I.

Diabetes. 2018 Jun;67(6):1068-1078. doi: 10.2337/db17-0706. Epub 2018 Mar 26.

47.

Human pancreatic α- to β-cell area ratio increases after type 2 diabetes onset.

Fujita Y, Kozawa J, Iwahashi H, Yoneda S, Uno S, Eguchi H, Nagano H, Imagawa A, Shimomura I.

J Diabetes Investig. 2018 Nov;9(6):1270-1282. doi: 10.1111/jdi.12841. Epub 2018 Apr 22.

48.

Clinical Utility of Carotid Ultrasonography in the Prediction of Cardiovascular Events in Patients with Diabetes: A Combined Analysis of Data Obtained in Five Longitudinal Studies.

Katakami N, Mita T, Gosho M, Takahara M, Irie Y, Yasuda T, Matsuoka TA, Osonoi T, Watada H, Shimomura I.

J Atheroscler Thromb. 2018 Oct 1;25(10):1053-1066. doi: 10.5551/jat.43141. Epub 2018 Feb 14.

49.

Effect of sitagliptin on tissue characteristics of the carotid wall in patients with type 2 diabetes: a post hoc sub-analysis of the sitagliptin preventive study of intima-media thickness evaluation (SPIKE).

Katakami N, Mita T, Irie Y, Takahara M, Matsuoka TA, Gosho M, Watada H, Shimomura I; Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE) Collaborators.

Cardiovasc Diabetol. 2018 Feb 5;17(1):24. doi: 10.1186/s12933-018-0666-3.

50.

Evaluation of the Effect of Alogliptin on Tissue Characteristics of the Carotid Wall: Subanalysis of the SPEAD-A Trial.

Irie Y, Katakami N, Mita T, Takahara M, Matsuoka TA, Gosho M, Watada H, Shimomura I; Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) Collaborators.

Diabetes Ther. 2018 Feb;9(1):317-329. doi: 10.1007/s13300-018-0367-7. Epub 2018 Jan 12.

Supplemental Content

Loading ...
Support Center