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Items: 1 to 50 of 411

1.

Impact of drinking and smoking habits on cerebrovascular disease risk among male employees.

Hatanaka Y, Shimokata K, Osugi S, Kaneko N.

Sangyo Eiseigaku Zasshi. 2016 Oct 7;58(5):155-163. Epub 2016 Aug 4. Japanese.

2.

Serum uric acid as a predictor of future hypertension: Stratified analysis based on body mass index and age.

Yokoi Y, Kondo T, Okumura N, Shimokata K, Osugi S, Maeda K, Murohara T.

Prev Med. 2016 Sep;90:201-6. doi: 10.1016/j.ypmed.2016.07.007. Epub 2016 Jul 9.

3.

Smoking acutely impaired endothelial function in healthy college students.

Miyata S, Noda A, Ito Y, Iizuka R, Shimokata K.

Acta Cardiol. 2015 Jun;70(3):282-5.

PMID:
26226701
4.

Cefepime monotherapy for febrile neutropenia in patients with lung cancer.

Saito H, Takahashi K, Okuno M, Saka H, Imaizumi K, Hasegawa Y, Tanikawa Y, Yamamoto M, Taniguchi H, Shindoh J, Suzuki R, Shimokata K; Central Japan Lung Study Group.

J Infect Chemother. 2014 Jun;20(6):365-9. doi: 10.1016/j.jiac.2014.02.002. Epub 2014 Mar 26.

PMID:
24679653
5.

Associations of proteinuria and the estimated glomerular filtration rate with incident hypertension in young to middle-aged Japanese males.

Okumura N, Kondo T, Matsushita K, Osugi S, Shimokata K, Matsudaira K, Yamashita K, Maeda K, Murohara T.

Prev Med. 2014 Mar;60:48-54. doi: 10.1016/j.ypmed.2013.12.009. Epub 2013 Dec 14.

6.

Effect of current smoking and blood pressure on cardiovascular events and mortality for workers: number of events for multivariate analysis to keep validity. Reply.

Kondo T, Osugi S, Shimokata K, Honjo H, Okumura N, Matsudaira K, Yamashita K, Maeda K, Muramatsu T, Shintani S, Matsushita K, Murohara T.

J Hypertens. 2013 Sep;31(9):1920-1. doi: 10.1097/HJH.0b013e328363e891. No abstract available.

PMID:
24107678
7.

A stabilizing factor for mitochondrial respiratory supercomplex assembly regulates energy metabolism in muscle.

Ikeda K, Shiba S, Horie-Inoue K, Shimokata K, Inoue S.

Nat Commun. 2013;4:2147. doi: 10.1038/ncomms3147.

PMID:
23857330
8.

Cardiovascular events increased at normal and high-normal blood pressure in young and middle-aged Japanese male smokers but not in nonsmokers.

Kondo T, Osugi S, Shimokata K, Honjo H, Okumura N, Matsudaira K, Yamashita K, Maeda K, Muramatsu T, Shintani S, Matsushita K, Murohara T.

J Hypertens. 2013 Feb;31(2):263-70. doi: 10.1097/HJH.0b013e32835b8d22.

PMID:
23160105
9.

Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice.

Ohno T, Okamoto M, Hara T, Hashimoto N, Imaizumi K, Matsushima M, Nishimura M, Shimokata K, Hasegawa Y, Kawabe T.

Immunogenetics. 2013 Jan;65(1):17-24. doi: 10.1007/s00251-012-0656-7. Epub 2012 Oct 19.

PMID:
23081743
10.

Aqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans.

Hashimoto I, Imaizumi K, Hashimoto N, Furukawa H, Noda Y, Kawabe T, Honda T, Ogawa T, Matsuo M, Imai N, Ito S, Sato M, Kondo M, Shimokata K, Hasegawa Y.

Respirology. 2013 Feb;18(2):340-7. doi: 10.1111/j.1440-1843.2012.02286.x.

PMID:
23062110
11.

The significance of measuring body fat percentage determined by bioelectrical impedance analysis for detecting subjects with cardiovascular disease risk factors.

Yamashita K, Kondo T, Osugi S, Shimokata K, Maeda K, Okumura N, Matsudaira K, Shintani S, Muramatsu T, Matsushita K, Murohara T.

Circ J. 2012;76(10):2435-42. Epub 2012 Jul 11.

12.

Nationwide, multicenter survey on the efficacy and safety of piperacillin for adult community-acquired pneumonia in Japan.

Yamamoto Y, Watanabe A, Goto H, Matsushima T, Abe S, Aoki N, Shimokata K, Mikasa K, Niki Y, Kohno S.

J Infect Chemother. 2012 Aug;18(4):544-51. doi: 10.1007/s10156-012-0417-4. Epub 2012 May 23.

PMID:
22618270
13.

Nationwide survey on the 2005 Guidelines for the Management of Community-Acquired Adult Pneumonia: validation of differentiation between bacterial pneumonia and atypical pneumonia.

Watanabe A, Goto H, Kohno S, Matsushima T, Abe S, Aoki N, Shimokata K, Mikasa K, Niki Y.

Respir Investig. 2012 Mar;50(1):23-32. doi: 10.1016/j.resinv.2012.02.003. Epub 2012 Mar 10.

14.

Nationwide survey on the 2005 Guidelines for the Management of Community-Acquired Adult Pneumonia: validation of severity assessment.

Watanabe A, Goto H, Kohno S, Matsushima T, Abe S, Aoki N, Shimokata K, Mikasa K, Niki Y.

Respir Investig. 2012 Mar;50(1):14-22. doi: 10.1016/j.resinv.2012.02.002. Epub 2012 Mar 10.

15.

Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium.

Sashio T, Kume H, Takeda N, Asano T, Tsuji S, Kondo M, Hasegawa Y, Shimokata K.

Allergol Int. 2012 Jun;61(2):283-93. doi: 10.2332/allergolint.10-OA-0299. Epub 2012 Feb 25.

16.

[Usage of gastric antisecretory drugs in palliative care of lung cancer patients].

Tanaka S, Kotani H, Miyazaki M, Hirabayashi A, Murosaki C, Yamashita K, Kishi R, Mouri A, Kondo M, Shimokata K, Hasegawa Y, Yamada K, Noda Y.

Gan To Kagaku Ryoho. 2012 Feb;39(2):251-6. Japanese.

PMID:
22333637
17.

Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells.

Hayashi Y, Matsushima M, Nakamura T, Shibasaki M, Hashimoto N, Imaizumi K, Shimokata K, Hasegawa Y, Kawabe T.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):169-74. doi: 10.1016/j.bbrc.2011.11.078. Epub 2011 Nov 25.

PMID:
22138401
18.

Smoking and smoking cessation in relation to all-cause mortality and cardiovascular events in 25,464 healthy male Japanese workers.

Kondo T, Osugi S, Shimokata K, Honjo H, Morita Y, Maeda K, Yamashita K, Muramatsu T, Shintani S, Matsushita K, Murohara T.

Circ J. 2011;75(12):2885-92. Epub 2011 Oct 6.

19.

ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility.

Maeda M, Hasegawa H, Hyodo T, Ito S, Asano E, Yuang H, Funasaka K, Shimokata K, Hasegawa Y, Hamaguchi M, Senga T.

Mol Biol Cell. 2011 Oct;22(20):3840-52. doi: 10.1091/mbc.E11-04-0364. Epub 2011 Aug 24.

20.

Metabolic syndrome and all-cause mortality, cardiac events, and cardiovascular events: a follow-up study in 25,471 young- and middle-aged Japanese men.

Kondo T, Osugi S, Shimokata K, Honjo H, Morita Y, Yamashita K, Maeda K, Muramatsu T, Shintani S, Matsushita K, Murohara T.

Eur J Cardiovasc Prev Rehabil. 2011 Aug;18(4):574-80. doi: 10.1177/1741826710389529. Epub 2011 Feb 14.

PMID:
21450628
21.

Phase II study of S-1 monotherapy as a first-line treatment for elderly patients with advanced nonsmall-cell lung cancer: the Central Japan Lung Study Group trial 0404.

Nishiyama O, Taniguchi H, Kondoh Y, Takada K, Baba K, Saito H, Sugino Y, Yamamoto M, Ogasawara T, Kondo M, Imaizumi K, Hasegawa Y, Suzuki R, Shimokata K; Central Japan Lung Study Group.

Anticancer Drugs. 2011 Sep;22(8):811-6. doi: 10.1097/CAD.0b013e3283440231.

PMID:
21317767
22.

Attenuation of transforming growth factor-β-stimulated collagen production in fibroblasts by quercetin-induced heme oxygenase-1.

Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y, Kawabe T.

Am J Respir Cell Mol Biol. 2011 May;44(5):614-20. doi: 10.1165/rcmb.2010-0338OC. Epub 2011 Jan 7.

PMID:
21216973
23.

Phase II study of carboplatin and gemcitabine as adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: a report from the Central Japan Lung Study Group, CJLSG 0503 trial.

Usami N, Yokoi K, Hasegawa Y, Taniguchi H, Shindo J, Yamamoto M, Suzuki R, Imaizumi K, Kondo M, Shimokata K; Central Japan Lung Study Group.

Int J Clin Oncol. 2010 Dec;15(6):583-7. doi: 10.1007/s10147-010-0118-x. Epub 2010 Aug 17.

PMID:
20714770
24.

Cell-free synthesis of cytochrome c oxidase, a multicomponent membrane protein.

Katayama Y, Shimokata K, Suematsu M, Ogura T, Tsukihara T, Yoshikawa S, Shimada H.

J Bioenerg Biomembr. 2010 Jun;42(3):235-40. doi: 10.1007/s10863-010-9285-8. Epub 2010 Apr 6.

PMID:
20373004
25.

Differential Th1/Th2 chemokine expression in interstitial pneumonia.

Honda T, Imaizumi K, Yokoi T, Hashimoto N, Hashimoto I, Kawabe T, Matsuo M, Iwano S, Shimokata K, Hasegawa Y.

Am J Med Sci. 2010 Jan;339(1):41-8. doi: 10.1097/MAJ.0b013e3181c14aaa.

PMID:
20057276
26.

Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma.

Goto Y, Shinjo K, Kondo Y, Shen L, Toyota M, Suzuki H, Gao W, An B, Fujii M, Murakami H, Osada H, Taniguchi T, Usami N, Kondo M, Hasegawa Y, Shimokata K, Matsuo K, Hida T, Fujimoto N, Kishimoto T, Issa JP, Sekido Y.

Cancer Res. 2009 Dec 1;69(23):9073-82. doi: 10.1158/0008-5472.CAN-09-1595. Epub 2009 Nov 3.

27.

Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis.

Hashimoto N, Phan SH, Imaizumi K, Matsuo M, Nakashima H, Kawabe T, Shimokata K, Hasegawa Y.

Am J Respir Cell Mol Biol. 2010 Aug;43(2):161-72. doi: 10.1165/rcmb.2009-0031OC. Epub 2009 Sep 18.

28.

Erythromycin-induced CXCR4 expression on microvascular endothelial cells.

Takagi Y, Hashimoto N, Phan SH, Imaizumi K, Matsuo M, Nakashima H, Hashimoto I, Hayashi Y, Kawabe T, Shimokata K, Hasegawa Y.

Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L420-31. doi: 10.1152/ajplung.90477.2008. Epub 2009 Jun 5.

29.

An influence of Interferon-gamma gene polymorphisms on treatment response to tuberculosis in Japanese population.

Shibasaki M, Yagi T, Yatsuya H, Okamoto M, Nishikawa M, Baba H, Hashimoto N, Senda K, Kawabe T, Nakashima K, Imaizumi K, Shimokata K, Hasegawa Y.

J Infect. 2009 Jun;58(6):467-9. doi: 10.1016/j.jinf.2009.04.002. Epub 2009 Apr 17. No abstract available.

PMID:
19427704
30.

Activation of the PI3K-AKT pathway in human malignant mesothelioma cells.

Suzuki Y, Murakami H, Kawaguchi K, Tanigushi T, Fujii M, Shinjo K, Kondo Y, Osada H, Shimokata K, Horio Y, Hasegawa Y, Hida T, Sekido Y.

Mol Med Rep. 2009 Mar-Apr;2(2):181-8. doi: 10.3892/mmr_00000081.

PMID:
21475810
31.

Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.

Shiraki A, Kume H, Oguma T, Makino Y, Ito S, Shimokata K, Honjo H, Kamiya K.

Clin Exp Allergy. 2009 Feb;39(2):236-45. doi: 10.1111/j.1365-2222.2008.03164.x. Epub 2008 Dec 23.

PMID:
19134015
32.

Up-regulation of surfactant protein production in a mouse model of secondary pulmonary alveolar proteinosis.

Shibasaki M, Hashimoto K, Okamoto M, Hayashi Y, Imaizumi K, Hashimoto N, Ozaki N, Yokoi T, Takagi K, Hasegawa Y, Shimokata K, Kawabe T.

Am J Respir Cell Mol Biol. 2009 May;40(5):536-42. doi: 10.1165/rcmb.2008-0103OC. Epub 2008 Oct 17.

PMID:
18931325
33.

YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation.

Yokoyama T, Osada H, Murakami H, Tatematsu Y, Taniguchi T, Kondo Y, Yatabe Y, Hasegawa Y, Shimokata K, Horio Y, Hida T, Sekido Y.

Carcinogenesis. 2008 Nov;29(11):2139-46. doi: 10.1093/carcin/bgn200. Epub 2008 Aug 25.

PMID:
18725387
34.

Dual pathway activated by tert-butyl hydroperoxide in human airway anion secretion.

Matsuno T, Ito Y, Ohashi T, Morise M, Takeda N, Shimokata K, Imaizumi K, Kume H, Hasegawa Y.

J Pharmacol Exp Ther. 2008 Nov;327(2):453-64. doi: 10.1124/jpet.108.141580. Epub 2008 Jul 29.

PMID:
18664589
35.

Role of Ca(2+) mobilization in desensitization of beta-adrenoceptors by platelet-derived growth factor in airway smooth muscle.

Ikenouchi T, Kume H, Oguma T, Makino Y, Shiraki A, Ito Y, Shimokata K.

Eur J Pharmacol. 2008 Sep 4;591(1-3):259-65. doi: 10.1016/j.ejphar.2008.06.072. Epub 2008 Jun 27.

PMID:
18611401
36.

TH1/TH2 immune response in lung fibroblasts in interstitial lung disease.

Sumida A, Hasegawa Y, Okamoto M, Hashimoto N, Imaizumi K, Yatsuya H, Yokoi T, Takagi K, Shimokata K, Kawabe T.

Arch Med Res. 2008 Jul;39(5):503-10. doi: 10.1016/j.arcmed.2008.02.005. Epub 2008 Apr 18.

PMID:
18514095
37.

A phase II study of carboplatin and paclitacel with meloxicam.

Suzuki R, Yamamoto M, Saka H, Taniguchi H, Shindoh J, Tanikawa Y, Nomura F, Gonda H, Imaizumi K, Hasegawa Y, Shimokata K.

Lung Cancer. 2009 Jan;63(1):72-6. doi: 10.1016/j.lungcan.2008.04.002. Epub 2008 May 21.

PMID:
18499296
38.

mRNA expression of RRM1, ERCC1 and ERCC2 is not associated with chemosensitivity to cisplatin, carboplatin and gemcitabine in human lung cancer cell lines.

Shimizu J, Horio Y, Osada H, Hida T, Hasegawa Y, Shimokata K, Takahashi T, Sekido Y, Yatabe Y.

Respirology. 2008 Jun;13(4):510-7. doi: 10.1111/j.1440-1843.2008.01302.x.

PMID:
18494946
39.

[Prevalence of myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) in patients with interstitial pneumonia].

Shiraki A, Ando M, Shindoh J, Abe T, Wakahara K, Makino Y, Asano T, Nakashima H, Hase T, Shigemitsu K, Horiba M, Shimokata K.

Nihon Kokyuki Gakkai Zasshi. 2007 Dec;45(12):921-6. Japanese.

PMID:
18186236
40.

A Japanese Lung Cancer Registry study: prognosis of 13,010 resected lung cancers.

Asamura H, Goya T, Koshiishi Y, Sohara Y, Eguchi K, Mori M, Nakanishi Y, Tsuchiya R, Shimokata K, Inoue H, Nukiwa T, Miyaoka E; Japanese Joint Committee of Lung Cancer Registry.

J Thorac Oncol. 2008 Jan;3(1):46-52. doi: 10.1097/JTO.0b013e31815e8577.

41.

Mast cell tryptase causes homologous desensitization of beta-adrenoceptors by Ca2+ sensitization in tracheal smooth muscle.

Kobayashi M, Kume H, Oguma T, Makino Y, Ito Y, Shimokata K.

Clin Exp Allergy. 2008 Jan;38(1):135-44. Epub 2007 Nov 19.

PMID:
18028457
42.

SLC11A1 (formerly NRAMP1) polymorphisms associated with multidrug-resistant tuberculosis.

Takahashi K, Hasegawa Y, Abe T, Yamamoto T, Nakashima K, Imaizumi K, Shimokata K.

Tuberculosis (Edinb). 2008 Jan;88(1):52-7. Epub 2007 Oct 18.

PMID:
17950034
43.

Repeated instillations of Dermatophagoides farinae into the airways can induce Th2-dependent airway hyperresponsiveness, eosinophilia and remodeling in mice: effect of intratracheal treatment of fluticasone propionate.

Wakahara K, Tanaka H, Takahashi G, Tamari M, Nasu R, Toyohara T, Takano H, Saito S, Inagaki N, Shimokata K, Nagai H.

Eur J Pharmacol. 2008 Jan 6;578(1):87-96. Epub 2007 Sep 20.

PMID:
17915213
44.

A long-term study of sharps injuries among health care workers in Japan.

Nagao Y, Baba H, Torii K, Nagao M, Hatakeyama K, Iinuma Y, Ichiyama S, Shimokata K, Ohta M.

Am J Infect Control. 2007 Aug;35(6):407-11.

PMID:
17660012
45.

Macrophage-derived chemokine in malignant and tuberculous pleural effusions.

Okamoto M, Imaizumi K, Hasegawa Y, Hashimoto N, Sumida A, Shibazaki M, Takagi K, Shimokata K, Kawabe T.

Respirology. 2007 Jul;12(4):581-4.

PMID:
17587426
46.

Roles of P2X receptors and Ca2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle.

Oguma T, Ito S, Kondo M, Makino Y, Shimokata K, Honjo H, Kamiya K, Kume H.

Clin Exp Allergy. 2007 Jun;37(6):893-900.

PMID:
17517103
47.

Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges.

Taki F, Kume H, Kobayashi T, Ohta H, Aratake H, Shimokata K.

Clin Exp Allergy. 2007 Apr;37(4):599-607.

PMID:
17430358
48.

The proton pumping pathway of bovine heart cytochrome c oxidase.

Shimokata K, Katayama Y, Murayama H, Suematsu M, Tsukihara T, Muramoto K, Aoyama H, Yoshikawa S, Shimada H.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4200-5. Epub 2007 Feb 28.

49.

Pharmacogenetic approach for cancer treatment-tailored medicine in practice.

Hasegawa Y, Ando Y, Ando M, Hashimoto N, Imaizumi K, Shimokata K.

Ann N Y Acad Sci. 2006 Nov;1086:223-32. Review.

PMID:
17185519
50.

Direct effects of hydrogen peroxide on airway smooth muscle tone: roles of Ca2+ influx and Rho-kinase.

Kojima K, Kume H, Ito S, Oguma T, Shiraki A, Kondo M, Ito Y, Shimokata K.

Eur J Pharmacol. 2007 Feb 5;556(1-3):151-6. Epub 2006 Nov 10.

PMID:
17157292

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