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Genetic abnormalities in a large cohort of Coffin-Siris syndrome patients.

Sekiguchi F, Tsurusaki Y, Okamoto N, Teik KW, Mizuno S, Suzumura H, Isidor B, Ong WP, Haniffa M, White SM, Matsuo M, Saito K, Phadke S, Kosho T, Yap P, Goyal M, Clarke LA, Sachdev R, McGillivray G, Leventer RJ, Patel C, Yamagata T, Osaka H, Hisaeda Y, Ohashi H, Shimizu K, Nagasaki K, Hamada J, Dateki S, Sato T, Chinen Y, Awaya T, Kato T, Iwanaga K, Kawai M, Matsuoka T, Shimoji Y, Tan TY, Kapoor S, Gregersen N, Rossi M, Marie-Laure M, McGregor L, Oishi K, Mehta L, Gillies G, Lockhart PJ, Pope K, Shukla A, Girisha KM, Abdel-Salam GMH, Mowat D, Coman D, Kim OH, Cordier MP, Gibson K, Milunsky J, Liebelt J, Cox H, El Chehadeh S, Toutain A, Saida K, Aoi H, Minase G, Tsuchida N, Iwama K, Uchiyama Y, Suzuki T, Hamanaka K, Azuma Y, Fujita A, Imagawa E, Koshimizu E, Takata A, Mitsuhashi S, Miyatake S, Mizuguchi T, Miyake N, Matsumoto N.

J Hum Genet. 2019 Sep 17. doi: 10.1038/s10038-019-0667-4. [Epub ahead of print]


Wild boars: A potential source of Erysipelothrix rhusiopathiae infection in Japan.

Shimoji Y, Osaki M, Ogawa Y, Shiraiwa K, Nishikawa S, Eguchi M, Yamamoto T, Tsutsui T.

Microbiol Immunol. 2019 Aug 2. doi: 10.1111/1348-0421.12736. [Epub ahead of print]


Disassociation of Spa type and serovar of an Erysipelothrix rhusiopathiae serovar 6 strain isolated from a diseased pig.

Shimoji Y, Bito M, Shiraiwa K, Ogawa Y, Nishikawa S, Eguchi M.

J Vet Diagn Invest. 2019 May;31(3):488-491. doi: 10.1177/1040638719835883. Epub 2019 Mar 11.


Draft Genome Sequences of Lawsonia intracellularis Swine Strains Causing Proliferative Enteropathy in Japan.

Nishikawa S, Ogawa Y, Eguchi M, Rambukkana A, Shimoji Y.

Microbiol Resour Announc. 2018 Sep 6;7(9). pii: e01021-18. doi: 10.1128/MRA.01021-18. eCollection 2018 Sep.


Identification of serovar 1a, 1b, 2, and 5 strains of Erysipelothrix rhusiopathiae by a conventional gel-based PCR.

Shiraiwa K, Ogawa Y, Nishikawa S, Eguchi M, Shimoji Y.

Vet Microbiol. 2018 Nov;225:101-104. doi: 10.1016/j.vetmic.2018.09.014. Epub 2018 Sep 18.


Microsurgical lymphaticovenular anastomosis for refractory chylous ascites following para-aortic lymph nodes dissection in a patient with tubal cancer.

Arakaki Y, Shimoji Y, Yamazaki S, Shimizu Y, Aoki Y.

Gynecol Oncol Rep. 2018 Oct 1;26:53-55. doi: 10.1016/j.gore.2018.09.004. eCollection 2018 Nov.


Identification of the Chromosomal Region Essential for Serovar-Specific Antigen and Virulence of Serovar 1 and 2 Strains of Erysipelothrix rhusiopathiae.

Ogawa Y, Shiraiwa K, Nishikawa S, Eguchi M, Shimoji Y.

Infect Immun. 2018 Aug 22;86(9). pii: e00324-18. doi: 10.1128/IAI.00324-18. Print 2018 Sep.


Lymphatic vessel involvement is predictive for lymph node metastasis and an important prognostic factor in endometrial cancer.

Wakayama A, Kudaka W, Matsumoto H, Aoyama H, Ooyama T, Taira Y, Arakaki Y, Shimoji Y, Nakasone T, Nishihira K, Kaneshima I, Tamaki T, Yoshimi N, Aoki Y.

Int J Clin Oncol. 2018 Jun;23(3):532-538. doi: 10.1007/s10147-017-1227-6. Epub 2017 Dec 23.


Therapy-free interval has prognostic value in patients with recurrent cervical cancer treated with chemotherapy following definitive concurrent chemoradiotherapy.

Kozaki M, Sakuma S, Kudaka W, Kinjyo Y, Taira Y, Arakaki Y, Shimoji Y, Nakasone T, Nakamoto T, Wakayama A, Ooyama T, Aoki Y.

Arch Gynecol Obstet. 2017 Nov;296(5):997-1003. doi: 10.1007/s00404-017-4520-8. Epub 2017 Sep 7.


Concurrent weekly cisplatin versus triweekly cisplatin with radiotherapy for locally advanced squamous-cell carcinoma of the cervix: a retrospective analysis from a single institution.

Kinjyo Y, Nagai Y, Toita T, Kudaka W, Ariga T, Shimoji Y, Nakasone T, Taira Y, Arakaki Y, Nakamoto T, Wakayama A, Ooyama T, Maemoto H, Heianna J, Aoki Y.

Br J Radiol. 2017 Aug;90(1076):20170241. doi: 10.1259/bjr.20170241. Epub 2017 Jul 14.


Multiplex PCR assay for the simultaneous detection and differentiation of clonal lineages of Erysipelothrix rhusiopathiae serovar 1a strains currently circulating in Japan.

Shiraiwa K, Ogawa Y, Nishikawa S, Eguchi M, Shimoji Y.

J Vet Med Sci. 2017 Aug 4;79(8):1318-1322. doi: 10.1292/jvms.17-0255. Epub 2017 Jun 22.


Determination of O:4 antigen-antibody affinity level in O:5 antigen positive and negative variants of Salmonella enterica serovar Typhimurium.

Nakai Y, Ito A, Ogawa Y, Aribam SD, Elsheimer-Matulova M, Shiraiwa K, Kisaka SMB, Hikono H, Nishikawa S, Akiba M, Kawahara K, Shimoji Y, Eguchi M.

FEMS Microbiol Lett. 2017 Apr 1;364(7). doi: 10.1093/femsle/fnx062.


Clonal Lineages of Erysipelothrix rhusiopathiae Responsible for Acute Swine Erysipelas in Japan Identified by Using Genome-Wide Single-Nucleotide Polymorphism Analysis.

Ogawa Y, Shiraiwa K, Ogura Y, Ooka T, Nishikawa S, Eguchi M, Hayashi T, Shimoji Y.

Appl Environ Microbiol. 2017 May 17;83(11). pii: e00130-17. doi: 10.1128/AEM.00130-17. Print 2017 Jun 1.


Single nucleotide polymorphism genotyping of Erysipelothrix rhusiopathiae isolates from pigs affected with chronic erysipelas in Japan.

Shiraiwa K, Ogawa Y, Nishikawa S, Kusumoto M, Eguchi M, Shimoji Y.

J Vet Med Sci. 2017 Apr 5;79(4):699-701. doi: 10.1292/jvms.17-0040. Epub 2017 Mar 2.


A heat-sinking self-referencing fiber optic emission probe.

Djeu N, Shimoji Y.

Rev Sci Instrum. 2016 Sep;87(9):093112.


Improved Neural Processing Efficiency in a Chronic Aphasia Patient Following Melodic Intonation Therapy: A Neuropsychological and Functional MRI Study.

Tabei KI, Satoh M, Nakano C, Ito A, Shimoji Y, Kida H, Sakuma H, Tomimoto H.

Front Neurol. 2016 Sep 19;7:148. eCollection 2016.


Specific Monoclonal Antibody Overcomes the Salmonella enterica Serovar Typhimurium's Adaptive Mechanisms of Intramacrophage Survival and Replication.

Aribam SD, Harada T, Elsheimer-Matulova M, Iwata T, Kanehira K, Hikono H, Matsui H, Ogawa Y, Shimoji Y, Eguchi M.

PLoS One. 2016 Mar 17;11(3):e0151352. doi: 10.1371/journal.pone.0151352. eCollection 2016.


Variation in antigen-antibody affinity among serotypes of Salmonella O4 serogroup, determined using specific antisera.

Aribam SD, Elsheimer-Matulova M, Matsui H, Hirota J, Shiraiwa K, Ogawa Y, Hikono H, Shimoji Y, Eguchi M.

FEMS Microbiol Lett. 2015 Nov;362(21). pii: fnv168. doi: 10.1093/femsle/fnv168. Epub 2015 Sep 14.


Development of an SNP-based PCR assay for rapid differentiation of a Japanese live vaccine strain from field isolates of Erysipelothrix rhusiopathiae.

Shiraiwa K, Ogawa Y, Eguchi M, Hikono H, Kusumoto M, Shimoji Y.

J Microbiol Methods. 2015 Oct;117:11-3. doi: 10.1016/j.mimet.2015.07.001. Epub 2015 Jul 4.


Disease progression of HIV-1 infection in symptomatic and asymptomatic seroconverters in Osaka, Japan: a retrospective observational study.

Watanabe D, Suzuki S, Ashida M, Shimoji Y, Hirota K, Ogawa Y, Yajima K, Kasai D, Nishida Y, Uehira T, Shirasaka T.

AIDS Res Ther. 2015 May 22;12:19. doi: 10.1186/s12981-015-0059-6. eCollection 2015.


Monoclonal antibody-based competitive enzyme-linked immunosorbent assay to detect antibodies to O:4 Salmonella in the sera of livestock and poultry.

Aribam SD, Ogawa Y, Matsui H, Hirota J, Okamura M, Akiba M, Shimoji Y, Eguchi M.

J Microbiol Methods. 2015 Jan;108:1-3. doi: 10.1016/j.mimet.2014.11.002. Epub 2014 Nov 13.


Evaluation of the live vaccine efficacy of virulence plasmid-cured, and phoP- or aroA-deficient Salmonella enterica serovar Typhimurium in mice.

Matsui H, Isshiki Y, Eguchi M, Ogawa Y, Shimoji Y.

J Vet Med Sci. 2015 Feb;77(2):181-6. doi: 10.1292/jvms.14-0013. Epub 2014 Oct 24.


Erysipelas in a free-range layer flock with conjunctival oedema as an unusual clinical sign.

Schmitt F, Schade B, Böhm B, Shimoji Y, Pfahler C.

Berl Munch Tierarztl Wochenschr. 2014 May-Jun;127(5-6):183-7.


Phosphorylcholine and SpaA, a choline-binding protein, are involved in the adherence of Erysipelothrix rhusiopathiae to porcine endothelial cells, but this adherence is not mediated by the PAF receptor.

Harada T, Ogawa Y, Eguchi M, Shi F, Sato M, Uchida K, Nakayama H, Shimoji Y.

Vet Microbiol. 2014 Aug 6;172(1-2):216-22. doi: 10.1016/j.vetmic.2014.04.012. Epub 2014 May 9.


A rapid differentiation method for enteroinvasive Escherichia coli.

Aribam SD, Hirota J, Kusumoto M, Harada T, Shiraiwa K, Ogawa Y, Shimoji Y, Eguchi M.

J Microbiol Methods. 2014 Mar;98:64-6. doi: 10.1016/j.mimet.2013.11.012. Epub 2014 Jan 9.


Development of a loop-mediated isothermal amplification assay for rapid and simple detection of Erysipelothrix rhusiopathiae.

Yamazaki Y, Oba E, Kashiwagi N, Sugita K, Shiiba K, Baba Y, Shimoji Y, Yamazaki W.

Lett Appl Microbiol. 2014 Apr;58(4):362-9. doi: 10.1111/lam.12198. Epub 2013 Dec 11.


Characterization and identification of a novel candidate vaccine protein through systematic analysis of extracellular proteins of Erysipelothrix rhusiopathiae.

Shi F, Ogawa Y, Sano A, Harada T, Hirota J, Eguchi M, Oishi E, Shimoji Y.

Infect Immun. 2013 Dec;81(12):4333-40. doi: 10.1128/IAI.00549-13. Epub 2013 Sep 9.


Erysipelothrix rhusiopathiae exploits cytokeratin 18-positive epithelial cells of porcine tonsillar crypts as an invasion gateway.

Harada T, Ogawa Y, Eguchi M, Shi F, Sato M, Uchida K, Nakayama H, Shimoji Y.

Vet Immunol Immunopathol. 2013 Jun 15;153(3-4):260-6. doi: 10.1016/j.vetimm.2013.03.013. Epub 2013 Mar 30.


Capsular polysaccharide of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, and its modification with phosphorylcholine.

Shi F, Harada T, Ogawa Y, Ono H, Ohnishi-Kameyama M, Miyamoto T, Eguchi M, Shimoji Y.

Infect Immun. 2012 Nov;80(11):3993-4003. doi: 10.1128/IAI.00635-12. Epub 2012 Sep 4.


Immunostimulatory effects of recombinant Erysipelothrix rhusiopathiae expressing porcine interleukin-18 in mice and pigs.

Ogawa Y, Minagawa Y, Shi F, Eguchi M, Muneta Y, Shimoji Y.

Clin Vaccine Immunol. 2012 Sep;19(9):1393-8. doi: 10.1128/CVI.00342-12. Epub 2012 Jul 3.


Collagen adhesin-nanoparticle interaction impairs adhesin's ligand binding mechanism.

Devi AS, Ogawa Y, Shimoji Y, Balakumar S, Ponnuraj K.

Biochim Biophys Acta. 2012 Jul;1820(7):819-28. doi: 10.1016/j.bbagen.2012.04.006. Epub 2012 Apr 17.


New sensitive competitive enzyme-linked immunosorbent assay using a monoclonal antibody against nonstructural protein 1 of West Nile virus NY99.

Hirota J, Shimoji Y, Shimizu S.

Clin Vaccine Immunol. 2012 Feb;19(2):277-83. doi: 10.1128/CVI.05382-11. Epub 2011 Dec 21.


A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.

Takatsuka M, Osada-Oka M, Satoh EF, Kitadokoro K, Nishiuchi Y, Niki M, Inoue M, Iwai K, Arakawa T, Shimoji Y, Ogura H, Kobayashi K, Rambukkana A, Matsumoto S.

PLoS One. 2011;6(6):e20985. doi: 10.1371/journal.pone.0020985. Epub 2011 Jun 16.


The genome of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas, reveals new insights into the evolution of firmicutes and the organism's intracellular adaptations.

Ogawa Y, Ooka T, Shi F, Ogura Y, Nakayama K, Hayashi T, Shimoji Y.

J Bacteriol. 2011 Jun;193(12):2959-71. doi: 10.1128/JB.01500-10. Epub 2011 Apr 8.


Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of the collagen-binding region of RspB from Erysipelothrix rhusiopathiae.

Devi AS, Ogawa Y, Shimoji Y, Ponnuraj K.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1;66(Pt 2):156-9. doi: 10.1107/S1744309109035581. Epub 2010 Jan 27.


Oral vaccination against mycoplasmal pneumonia of swine using a live Erysipelothrix rhusiopathiae vaccine strain as a vector.

Ogawa Y, Oishi E, Muneta Y, Sano A, Hikono H, Shibahara T, Yagi Y, Shimoji Y.

Vaccine. 2009 Jul 16;27(33):4543-50. doi: 10.1016/j.vaccine.2009.04.081. Epub 2009 May 21.


Immune response of gnotobiotic piglets against Mycoplasma hyopneumoniae.

Muneta Y, Minagawa Y, Shimoji Y, Ogawa Y, Hikono H, Mori Y.

J Vet Med Sci. 2008 Oct;70(10):1065-70.


IL-18 expression in pigs following infection with Mycoplasma hyopneumoniae.

Muneta Y, Minagawa Y, Shimoji Y, Nagata R, Markham PF, Browning GF, Mori Y.

J Interferon Cytokine Res. 2006 Sep;26(9):637-44.


Different foreign genes incidentally integrated into the same locus of the Streptococcus suis genome.

Sekizaki T, Takamatsu D, Osaki M, Shimoji Y.

J Bacteriol. 2005 Feb;187(3):872-83.


Extract of Kurosu, a vinegar from unpolished rice, inhibits azoxymethane-induced colon carcinogenesis in male F344 rats.

Shimoji Y, Kohno H, Nanda K, Nishikawa Y, Ohigashi H, Uenakai K, Tanaka T.

Nutr Cancer. 2004;49(2):170-3.


Extract of vinegar "Kurosu" from unpolished rice inhibits the proliferation of human cancer cells.

Nanda K, Miyoshi N, Nakamura Y, Shimoji Y, Tamura Y, Nishikawa Y, Uenakai K, Kohno H, Tanaka T.

J Exp Clin Cancer Res. 2004 Mar;23(1):69-75.


Extract of vinegar "Kurosu" from unpolished rice inhibits the development of colonic aberrant crypt foci induced by azoxymethane.

Shimoji Y, Sugie S, Kohno H, Tanaka T, Nanda K, Tamura Y, Nishikawa Y, Hayashi R, Uenakai K, Ohigashi H.

J Exp Clin Cancer Res. 2003 Dec;22(4):591-7.


Porcine TLR2 and TLR6: identification and their involvement in Mycoplasma hyopneumoniae infection.

Muneta Y, Uenishi H, Kikuma R, Yoshihara K, Shimoji Y, Yamamoto R, Hamashima N, Yokomizo Y, Mori Y.

J Interferon Cytokine Res. 2003 Oct;23(10):583-90.


Synthesis and structure-activity relationships of novel parenteral carbapenems, CS-023 (R-115685) and related compounds containing an amidine moiety.

Kawamoto I, Shimoji Y, Kanno O, Kojima K, Ishikawa K, Matsuyama E, Ashida Y, Shibayama T, Fukuoka T, Ohya S.

J Antibiot (Tokyo). 2003 Jun;56(6):565-79. Erratum in: J Antibiot (Tokyo). 2003 Aug;56(8):C3.


Adhesive surface proteins of Erysipelothrix rhusiopathiae bind to polystyrene, fibronectin, and type I and IV collagens.

Shimoji Y, Ogawa Y, Osaki M, Kabeya H, Maruyama S, Mikami T, Sekizaki T.

J Bacteriol. 2003 May;185(9):2739-48.


Allelic variation in srtAs of Streptococcus suis strains.

Osaki M, Takamatsu D, Shimoji Y, Sekizaki T.

FEMS Microbiol Lett. 2003 Feb 28;219(2):195-201.


Expression of interleukin-18 by porcine airway and intestinal epithelium.

Muneta Y, Goji N, Tsuji NM, Mikami O, Shimoji Y, Nakajima Y, Yokomizo Y, Mori Y.

J Interferon Cytokine Res. 2002 Aug;22(8):883-9.


Isolation and identification of DPPH radical scavenging compounds in Kurosu (Japanese unpolished rice vinegar).

Shimoji Y, Tamura Y, Nakamura Y, Nanda K, Nishidai S, Nishikawa Y, Ishihara N, Uenakai K, Ohigashi H.

J Agric Food Chem. 2002 Oct 23;50(22):6501-3.


Hyaluronidase is not essential for the lethality of Erysipelothrix rhusiopathiae infection in mice.

Shimoji Y, Asato H, Sekizaki T, Mori Y, Yokomizo Y.

J Vet Med Sci. 2002 Feb;64(2):173-6.

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