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In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer Vaccination.

Shimodaira S, Yanagisawa R, Koya T, Hirabayashi K, Higuchi Y, Sakamoto T, Togi M, Kato T Jr, Kobayashi T, Koizumi T, Koido S, Sugiyama H.

Vaccines (Basel). 2019 Sep 19;7(3). pii: E120. doi: 10.3390/vaccines7030120.


Investigation of factors associated with allergic transfusion reaction due to platelet transfusion and the efficacy of platelets resuspended in BRS-A in adult patients.

Yamanaka M, Yanagisawa R, Kojima S, Nakazawa H, Shimodaira S.

Transfusion. 2019 Sep 18. doi: 10.1111/trf.15527. [Epub ahead of print]


Predicted Markers of Overall Survival in Pancreatic Cancer Patients Receiving Dendritic Cell Vaccinations Targeting WT1.

Ito Z, Kan S, Bito T, Horiuchi S, Akasu T, Yoshida S, Kajihara M, Hokari A, Saruta M, Yoshida N, Kobayashi M, Ohkusa T, Shimodaira S, Okamoto M, Sugiyama H, Koido S.

Oncology. 2019;97(3):135-148. doi: 10.1159/000500359. Epub 2019 Jun 19.


Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients.

Kojima S, Yanagisawa R, Tanaka M, Nakazawa Y, Shimodaira S.

Transfusion. 2018 Dec;58(12):2952-2958. doi: 10.1111/trf.14917. Epub 2018 Oct 6.


Synthesis of selenocysteine-containing cyclic peptides via tandem N-to-S acyl migration and intramolecular selenocysteine-mediated native chemical ligation.

Shimodaira S, Takei T, Hojo H, Iwaoka M.

Chem Commun (Camb). 2018 Oct 25;54(83):11737-11740. doi: 10.1039/c8cc06805d. Epub 2018 Oct 2.


Prognostic significance of Wilms' tumor 1 expression in patients with pancreatic ductal adenocarcinoma.

Kanai T, Ito Z, Oji Y, Suka M, Nishida S, Takakura K, Kajihara M, Saruta M, Fujioka S, Misawa T, Akiba T, Yanagisawa H, Shimodaira S, Okamoto M, Sugiyama H, Koido S.

Oncol Lett. 2018 Aug;16(2):2682-2692. doi: 10.3892/ol.2018.8961. Epub 2018 Jun 13.


Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors.

Hirabayashi K, Yanagisawa R, Saito S, Higuchi Y, Koya T, Sano K, Koido S, Okamoto M, Sugiyama H, Nakazawa Y, Shimodaira S.

Anticancer Res. 2018 Apr;38(4):2227-2234.


WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study.

Yanagisawa R, Koizumi T, Koya T, Sano K, Koido S, Nagai K, Kobayashi M, Okamoto M, Sugiyama H, Shimodaira S.

Anticancer Res. 2018 Apr;38(4):2217-2225.


Protein Folding in the Presence of Water-Soluble Cyclic Diselenides with Novel Oxidoreductase and Isomerase Activities.

Arai K, Ueno H, Asano Y, Chakrabarty G, Shimodaira S, Mugesh G, Iwaoka M.

Chembiochem. 2018 Feb 2;19(3):207-211. doi: 10.1002/cbic.201700624. Epub 2017 Dec 29.


Administration of platelet concentrates suspended in bicarbonated Ringer's solution in children who had platelet transfusion reactions.

Kobayashi J, Yanagisawa R, Ono T, Tatsuzawa Y, Tokutake Y, Kubota N, Hidaka E, Sakashita K, Kojima S, Shimodaira S, Nakamura T.

Vox Sang. 2018 Feb;113(2):128-135. doi: 10.1111/vox.12608. Epub 2017 Oct 25.


Selenoglutathione Diselenide: Unique Redox Reactions in the GPx-Like Catalytic Cycle and Repairing of Disulfide Bonds in Scrambled Protein.

Shimodaira S, Asano Y, Arai K, Iwaoka M.

Biochemistry. 2017 Oct 24;56(42):5644-5653. doi: 10.1021/acs.biochem.7b00751. Epub 2017 Oct 12.


Significance of Wilms' tumor 1 antigen as a cancer vaccine for pancreatic cancer.

Koido S, Okamoto M, Kobayashi M, Shimodaira S, Sugiyama H.

Discov Med. 2017 Aug;24(130):41-49. Review.


Interferon-α-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity.

Koya T, Yanagisawa R, Higuchi Y, Sano K, Shimodaira S.

Sci Rep. 2017 Feb 13;7:42145. doi: 10.1038/srep42145.


Wilms' tumor 1 (WT1)-targeted cancer vaccines to extend survival for patients with pancreatic cancer.

Koido S, Okamoto M, Shimodaira S, Sugiyama H.

Immunotherapy. 2016 Nov;8(11):1309-1320. Review.


Dendritic Cell-Based Cancer Immunotherapy Targeting Wilms’ Tumor 1 for Pediatric Cancer.

Shimodaira S, Hirabayashi K, Yanagisawa R, Higuchi Y, Sano K, Koizumi T.

In: van den Heuvel-Eibrink MM, editor. Wilms Tumor [Internet]. Brisbane (AU): Codon Publications; 2016 Mar. Chapter 8.


Lung adenocarcinoma may be a more susceptive subtype to a dendritic cell-based cancer vaccine than other subtypes of non-small cell lung cancers: a multicenter retrospective analysis.

Takahashi H, Shimodaira S, Ogasawara M, Ota S, Kobayashi M, Abe H, Morita Y, Nagai K, Tsujitani S, Okamoto M, Suzuki Y, Nakanishi Y, Yonemitsu Y; DC Vaccine Study Group at the Japanese Society of Immunotherapy and Cell Therapy.

Cancer Immunol Immunother. 2016 Sep;65(9):1099-111. doi: 10.1007/s00262-016-1872-z. Epub 2016 Jul 22.


Transfusion-related acute lung injury in an infant.

Yanagisawa R, Takeuchi K, Kurata T, Sakashita K, Shimodaira S, Ishii E.

Pediatr Int. 2016 Jun;58(6):543-4. doi: 10.1111/ped.12951. No abstract available.


Advances in inducing adaptive immunity using cell-based cancer vaccines: Clinical applications in pancreatic cancer.

Kajihara M, Takakura K, Kanai T, Ito Z, Matsumoto Y, Shimodaira S, Okamoto M, Ohkusa T, Koido S.

World J Gastroenterol. 2016 May 14;22(18):4446-58. doi: 10.3748/wjg.v22.i18.4446. Review.


Dendritic cell-based cancer immunotherapy for colorectal cancer.

Kajihara M, Takakura K, Kanai T, Ito Z, Saito K, Takami S, Shimodaira S, Okamoto M, Ohkusa T, Koido S.

World J Gastroenterol. 2016 May 7;22(17):4275-86. doi: 10.3748/wjg.v22.i17.4275. Review.


Factors related to allergic transfusion reactions and febrile non-haemolytic transfusion reactions in children.

Yanagisawa R, Shimodaira S, Sakashita K, Hidaka Y, Kojima S, Nishijima F, Hidaka E, Shiohara M, Nakamura T.

Vox Sang. 2016 May;110(4):376-84. doi: 10.1111/vox.12373. Epub 2016 Jan 25.


Dendritic Cell-Based Adjuvant Vaccination Targeting Wilms' Tumor 1 in Patients with Advanced Colorectal Cancer.

Shimodaira S, Sano K, Hirabayashi K, Koya T, Higuchi Y, Mizuno Y, Yamaoka N, Yuzawa M, Kobayashi T, Ito K, Koizumi T.

Vaccines (Basel). 2015 Dec 11;3(4):1004-18. doi: 10.3390/vaccines3041004.


Enzyme-Linked Immunosorbent Spot Assay for the Detection of Wilms' Tumor 1-Specific T Cells Induced by Dendritic Cell Vaccination.

Higuchi Y, Koya T, Yuzawa M, Yamaoka N, Mizuno Y, Yoshizawa K, Hirabayashi K, Kobayashi T, Sano K, Shimodaira S.

Biomedicines. 2015 Dec 4;3(4):304-315. doi: 10.3390/biomedicines3040304.


Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review.

Yanagisawa R, Nakazawa Y, Sakashita K, Saito S, Tanaka M, Shiohara M, Shimodaira S, Koike K.

Int J Hematol. 2016 Jan;103(1):107-11. doi: 10.1007/s12185-015-1902-1. Epub 2015 Nov 19. Review.


Efficacy of Erythropoietin-Beta Injections During Autologous Blood Donation Before Spinal Deformity Surgery in Children and Teenagers.

Ikegami S, Takahashi J, Kuraishi S, Shimizu M, Futatsugi T, Uehara M, Horiuchi K, Shimodaira S, Kato H.

Spine (Phila Pa 1976). 2015 Nov;40(21):E1144-9. doi: 10.1097/BRS.0000000000001108.


Dendritic cell-based immunotherapy targeting Wilms' tumor 1 in patients with recurrent malignant glioma.

Sakai K, Shimodaira S, Maejima S, Udagawa N, Sano K, Higuchi Y, Koya T, Ochiai T, Koide M, Uehara S, Nakamura M, Sugiyama H, Yonemitsu Y, Okamoto M, Hongo K.

J Neurosurg. 2015 Oct;123(4):989-97. doi: 10.3171/2015.1.JNS141554. Epub 2015 Aug 7.


Repeated exposure rather than the total volume of transfused components may influence the incidence of allergic transfusion reactions.

Kato H, Nakayama T, Uruma M, Okuyama Y, Handa M, Tomiyama Y, Shimodaira S, Takamoto S.

Transfusion. 2015 Nov;55(11):2576-81. doi: 10.1111/trf.13201. Epub 2015 Jun 20.


Identification of GH15 Family Thermophilic Archaeal Trehalases That Function within a Narrow Acidic-pH Range.

Sakaguchi M, Shimodaira S, Ishida SN, Amemiya M, Honda S, Sugahara Y, Oyama F, Kawakita M.

Appl Environ Microbiol. 2015 Aug;81(15):4920-31. doi: 10.1128/AEM.00956-15. Epub 2015 May 15.


A retrospective observational study to assess adverse transfusion reactions of patients with and without prior transfusion history.

Kato H, Nakayama T, Uruma M, Okuyama Y, Handa M, Tomiyama Y, Shimodaira S, Takamoto S.

Vox Sang. 2015 Apr;108(3):243-50. doi: 10.1111/vox.12208. Epub 2014 Dec 23.


Therapeutic effect of intratumoral injections of dendritic cells for locally recurrent gastric cancer: a case report.

Kobayashi M, Sakabe T, Chiba A, Nakajima A, Okamoto M, Shimodaira S, Yonemitsu Y, Shibamoto Y, Suzuki N, Nagaya M; DC-vaccine study group at the Japan Society of Innovative Cell Therapy (J-SICT).

World J Surg Oncol. 2014 Dec 19;12:390. doi: 10.1186/1477-7819-12-390.


Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature.

Saito S, Yanagisawa R, Yoshikawa K, Higuchi Y, Koya T, Yoshizawa K, Tanaka M, Sakashita K, Kobayashi T, Kurata T, Hirabayashi K, Nakazawa Y, Shiohara M, Yonemitsu Y, Okamoto M, Sugiyama H, Koike K, Shimodaira S.

Cytotherapy. 2015 Mar;17(3):330-5. doi: 10.1016/j.jcyt.2014.10.003. Epub 2014 Dec 4.


The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer.

Kobayashi M, Chiba A, Izawa H, Yanagida E, Okamoto M, Shimodaira S, Yonemitsu Y, Shibamoto Y, Suzuki N, Nagaya M; DC-vaccine study group at the Japan Society of Innovative Cell Therapy (J-SICT).

J Ovarian Res. 2014 May 7;7:48. doi: 10.1186/1757-2215-7-48.


Treatment with chemotherapy and dendritic cells pulsed with multiple Wilms' tumor 1 (WT1)-specific MHC class I/II-restricted epitopes for pancreatic cancer.

Koido S, Homma S, Okamoto M, Takakura K, Mori M, Yoshizaki S, Tsukinaga S, Odahara S, Koyama S, Imazu H, Uchiyama K, Kajihara M, Arakawa H, Misawa T, Toyama Y, Yanagisawa S, Ikegami M, Kan S, Hayashi K, Komita H, Kamata Y, Ito M, Ishidao T, Yusa S, Shimodaira S, Gong J, Sugiyama H, Ohkusa T, Tajiri H.

Clin Cancer Res. 2014 Aug 15;20(16):4228-39. doi: 10.1158/1078-0432.CCR-14-0314. Epub 2014 Jul 23.


Storage of volume-reduced washed platelets in M-sol additive solution for 7 days.

Hirayama J, Fujihara M, Akino M, Kojima S, Yanagisawa R, Homma C, Kato T, Ikeda H, Azuma H, Shimodaira S, Takamoto S.

Transfusion. 2014 Dec;54(12):3173-7. doi: 10.1111/trf.12724. Epub 2014 Jun 4.


Prognostic factors related to add-on dendritic cell vaccines on patients with inoperable pancreatic cancer receiving chemotherapy: a multicenter analysis.

Kobayashi M, Shimodaira S, Nagai K, Ogasawara M, Takahashi H, Abe H, Tanii M, Okamoto M, Tsujitani S, Yusa S, Ishidao T, Kishimoto J, Shibamoto Y, Nagaya M, Yonemitsu Y; DC Vaccine Study Group at the Japan Society of Innovative Cell Therapy (J-SICT).

Cancer Immunol Immunother. 2014 Aug;63(8):797-806. doi: 10.1007/s00262-014-1554-7. Epub 2014 Apr 29.


Diamine oxidase activity levels in anorexia nervosa.

Takimoto Y, Yoshiuchi K, Shimodaira S, Akabayashi A.

Int J Eat Disord. 2014 Mar;47(2):203-5. doi: 10.1002/eat.22202. Epub 2013 Oct 30.


Incidence of transfusion-related adverse reactions per patient reflects the potential risk of transfusion therapy in Japan.

Kato H, Uruma M, Okuyama Y, Fujita H, Handa M, Tomiyama Y, Shimodaira S, Kurata Y, Takamoto S.

Am J Clin Pathol. 2013 Aug;140(2):219-24. doi: 10.1309/AJCP6SBPOX0UWHEK.


Dendritic cell-based immunotherapy targeting synthesized peptides for advanced biliary tract cancer.

Kobayashi M, Sakabe T, Abe H, Tanii M, Takahashi H, Chiba A, Yanagida E, Shibamoto Y, Ogasawara M, Tsujitani S, Koido S, Nagai K, Shimodaira S, Okamoto M, Yonemitsu Y, Suzuki N, Nagaya M; DC-vaccine study group at the Japan Society of Innovative Cell Therapy (J-SICT).

J Gastrointest Surg. 2013 Sep;17(9):1609-17. doi: 10.1007/s11605-013-2286-2. Epub 2013 Jul 20.


Immunochemoradiotherapy for patients with oral squamous cell carcinoma: augmentation of OK-432-induced helper T cell 1 response by 5-FU and X-ray irradiation.

Tano T, Okamoto M, Kan S, Bando T, Goda H, Nakashiro K, Shimodaira S, Koido S, Homma S, Fujita T, Sato M, Yamashita N, Hamakawa H, Kawakami Y.

Neoplasia. 2013 Jul;15(7):805-14.


Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis.

Shigemura T, Nakazawa Y, Yoshikawa K, Hirabayashi K, Saito S, Kobayashi N, Sakashita K, Shiohara M, Wada T, Shimodaira S, Agematsu K, Koike K.

Transfusion. 2014 Mar;54(3):516-21. doi: 10.1111/trf.12325. Epub 2013 Jun 30.


Prognostic impact of expression of Bcl-2 and Bax genes in circulating immune cells derived from patients with head and neck carcinoma.

Tano T, Okamoto M, Kan S, Nakashiro K, Shimodaira S, Koido S, Homma S, Sato M, Fujita T, Kawakami Y, Hamakawa H.

Neoplasia. 2013 Mar;15(3):305-14.


Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients.

Yanagisawa R, Shimodaira S, Kojima S, Nakasone N, Ishikawa S, Momose K, Honda T, Yoshikawa K, Saito S, Tanaka M, Nakazawa Y, Sakashita K, Shiohara M, Akino M, Hirayama J, Azuma H, Koike K.

Transfusion. 2013 Sep;53(9):2053-60. doi: 10.1111/trf.12025. Epub 2012 Dec 17.


Impact of dendritic cell vaccines pulsed with Wilms' tumour-1 peptide antigen on the survival of patients with advanced non-small cell lung cancers.

Takahashi H, Okamoto M, Shimodaira S, Tsujitani S, Nagaya M, Ishidao T, Kishimoto J, Yonemitsu Y; DC-vaccine study group at the Japan Society of Innovative Cell Therapy (J-SICT).

Eur J Cancer. 2013 Mar;49(4):852-9. doi: 10.1016/j.ejca.2012.11.005. Epub 2012 Dec 11.


Growth inhibition and apoptosis by an active component of OK-432, a streptococcal agent, via Toll-like receptor 4 in human head and neck cancer cell lines.

Tano T, Okamoto M, Kan S, Nakashiro K, Shimodaira S, Yamashita N, Kawakami Y, Hamakawa H.

Oral Oncol. 2012 Aug;48(8):678-85. doi: 10.1016/j.oraloncology.2012.02.005. Epub 2012 Mar 3.


Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma.

Kimura Y, Tsukada J, Tomoda T, Takahashi H, Imai K, Shimamura K, Sunamura M, Yonemitsu Y, Shimodaira S, Koido S, Homma S, Okamoto M.

Pancreas. 2012 Mar;41(2):195-205. doi: 10.1097/MPA.0b013e31822398c6.


The usefulness of pathogen inactivation during an outbreak of the new strain of influenza (H1N1).

Narimatsu H, Yuji K, Shimodaira S, Kami M.

Transfus Med Rev. 2010 Apr;24(2):151-2. doi: 10.1016/j.tmrv.2009.12.001. No abstract available.


The clinical characteristics of CD7+ CD56+ acute myeloid leukemias other than M0.

Suzuki R, Ohtake S, Takeuchi J, Nagai M, Kodera Y, Hamaguchi M, Miyawaki S, Karasuno T, Shimodaira S, Ohno R, Nakamura S, Naoe T.

Int J Hematol. 2010 Mar;91(2):303-9. doi: 10.1007/s12185-010-0492-1. Epub 2010 Jan 29.


Changes in angiogenesis-related factors in serum following autologous bone marrow cell implantation for severe limb ischemia.

Tachi Y, Fukui D, Wada Y, Koshikawa M, Shimodaira S, Ikeda U, Amano J.

Expert Opin Biol Ther. 2008 Jun;8(6):705-12. doi: 10.1517/14712598.8.6.705 .


Promising approach for aggressive NK cell leukaemia with allogeneic haematopoietic cell transplantation.

Ito T, Makishima H, Nakazawa H, Kobayashi H, Shimodaira S, Nakazawa Y, Kitano K, Matsuda K, Hidaka E, Ishida F.

Eur J Haematol. 2008 Aug;81(2):107-11. doi: 10.1111/j.1600-0609.2008.01090.x. Epub 2008 May 6.


Elevated osteopontin levels in patients with peripheral arterial disease.

Koshikawa M, Aizawa K, Kasai H, Izawa A, Tomita T, Kumazaki S, Tsutsui H, Koyama J, Shimodaira S, Takahashi M, Ikeda U.

Angiology. 2009 Feb-Mar;60(1):42-5. doi: 10.1177/0003319708314250. Epub 2008 Apr 2.


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