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Items: 1 to 50 of 763

1.

Alcohol drinking and bladder cancer risk from a pooled analysis of ten cohort studies in Japan.

Masaoka H, Matsuo K, Oze I, Ito H, Naito M, Wada K, Nagata C, Nakayama T, Kitamura Y, Sadakane A, Tamakoshi A, Tsuji I, Sugawara Y, Sawada N, Mizoue T, Inoue M, Tanaka K, Tsugane S, Shimazu T.

J Epidemiol. 2019 Jun 15. doi: 10.2188/jea.JE20190014. [Epub ahead of print]

2.

Food frequency questionnaire reproducibility for middle-aged and elderly Japanese.

Maruyama K, Ikeda A, Ishihara J, Takachi R, Sawada N, Shimazu T, Nakamura K, Tanaka J, Yamaji T, Iwasaki M, Iso H, Tsugane S; JPHC-NEXT Protocol Validation Study Group.

Asia Pac J Clin Nutr. 2019;28(2):362-370. doi: 10.6133/apjcn.201906_28(2).0019.

3.

Circulating sex hormone levels and colorectal cancer risk in Japanese postmenopausal women: The JPHC nested case-control study.

Mori N, Sawada N, Iwasaki M, Yamaji T, Goto A, Shimazu T, Inoue M, Murphy N, Gunter MJ, Tsugane S.

Int J Cancer. 2019 May 27. doi: 10.1002/ijc.32431. [Epub ahead of print]

PMID:
31131883
4.

Pelvic angiography is effective for emergency pediatric patients with pelvic fractures: a propensity-score-matching study with a nationwide trauma registry in Japan.

Katayama Y, Kitamura T, Hirose T, Kiguchi T, Matsuyama T, Takahashi H, Kiyohara K, Sado J, Adachi S, Noda T, Izawa J, Nakagawa Y, Shimazu T.

Eur J Trauma Emerg Surg. 2019 May 22. doi: 10.1007/s00068-019-01154-w. [Epub ahead of print]

PMID:
31119320
5.

Smoking and pancreatic cancer incidence: a pooled analysis of ten population-based cohort studies in Japan.

Koyanagi YN, Ito H, Matsuo K, Sugawara Y, Hidaka A, Sawada N, Wada K, Nagata C, Tamakoshi A, Lin Y, Takeuchi T, Kitamura Y, Utada M, Sadakane A, Mizoue T, Naito M, Tanaka K, Shimazu T, Tsugane S, Inoue M.

Cancer Epidemiol Biomarkers Prev. 2019 May 21. pii: cebp.1327.2018. doi: 10.1158/1055-9965.EPI-18-1327. [Epub ahead of print]

PMID:
31113869
6.

Serum potassium level on hospital arrival and survival after out-of-hospital cardiac arrest: The CRITICAL study in Osaka, Japan.

Shida H, Matsuyama T, Iwami T, Okabayashi S, Yamada T, Hayakawa K, Yoshiya K, Irisawa T, Noguchi K, Nishimura T, Uejima T, Yagi Y, Kiguchi T, Kishimoto M, Matsuura M, Hayashi Y, Sogabe T, Morooka T, Sado J, Kishimori T, Kiyohara K, Shimazu T, Kitamura T, Kawamura T.

Eur Heart J Acute Cardiovasc Care. 2019 May 13:2048872619848883. doi: 10.1177/2048872619848883. [Epub ahead of print]

PMID:
31081678
7.

Usefulness of cerebral rSO2 monitoring during CPR to predict the probability of return of spontaneous circulation.

Takegawa R, Shiozaki T, Ogawa Y, Hirose T, Mori N, Ohnishi M, Ishihara T, Shintani A, Shimazu T.

Resuscitation. 2019 Jun;139:201-207. doi: 10.1016/j.resuscitation.2019.04.015. Epub 2019 Apr 18.

8.

Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study.

Hirabayashi M, Inoue M, Sawada N, Saito E, Abe SK, Hidaka A, Iwasaki M, Yamaji T, Shimazu T, Tsugane S.

Sci Rep. 2019 Apr 15;9(1):6099. doi: 10.1038/s41598-019-42365-w.

9.

Coffee consumption and mortality in Japanese men and women: A pooled analysis of eight population-based cohort studies in Japan (Japan Cohort Consortium).

Abe SK, Saito E, Sawada N, Tsugane S, Ito H, Lin Y, Tamakoshi A, Sado J, Kitamura Y, Sugawara Y, Tsuji I, Nagata C, Sadakane A, Shimazu T, Mizoue T, Matsuo K, Naito M, Tanaka K, Inoue M; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

Prev Med. 2019 Jun;123:270-277. doi: 10.1016/j.ypmed.2019.04.002. Epub 2019 Apr 2.

PMID:
30951734
10.

Diabetes and cancer risk: A Mendelian randomization study.

Goto A, Yamaji T, Sawada N, Momozawa Y, Kamatani Y, Kubo M, Shimazu T, Inoue M, Noda M, Tsugane S, Iwasaki M.

Int J Cancer. 2019 Mar 30. doi: 10.1002/ijc.32310. [Epub ahead of print]

PMID:
30927373
11.

Association of dietary diversity with total mortality and major causes of mortality in the Japanese population: JPHC study.

Kobayashi M, Sasazuki S, Shimazu T, Sawada N, Yamaji T, Iwasaki M, Mizoue T, Tsugane S.

Eur J Clin Nutr. 2019 Mar 19. doi: 10.1038/s41430-019-0416-y. [Epub ahead of print]

PMID:
30890778
12.

Myeloid-Derived Suppressor Cells Infiltrate the Brain and Suppress Neuroinflammation in a Mouse Model of Focal Traumatic Brain Injury.

Hosomi S, Koyama Y, Watabe T, Ohnishi M, Ogura H, Yamashita T, Shimazu T.

Neuroscience. 2019 May 15;406:457-466. doi: 10.1016/j.neuroscience.2019.03.015. Epub 2019 Mar 14.

PMID:
30880103
13.

Circulating Inflammation Markers and Risk of Gastric and Esophageal Cancers: A Case-Cohort Study Within the Japan Public Health Center-Based Prospective Study.

Camargo MC, Song M, Shimazu T, Charvat H, Yamaji T, Sawada N, Kemp TJ, Pfeiffer RM, Hildesheim A, Pinto LA, Tsugane S, Rabkin CS.

Cancer Epidemiol Biomarkers Prev. 2019 Apr;28(4):829-832. doi: 10.1158/1055-9965.EPI-18-1157. Epub 2019 Mar 15.

PMID:
30877129
14.

Serum albumin as a risk factor for death in patients with prolonged sepsis: An observational study.

Takegawa R, Kabata D, Shimizu K, Hisano S, Ogura H, Shintani A, Shimazu T.

J Crit Care. 2019 Jun;51:139-144. doi: 10.1016/j.jcrc.2019.02.004. Epub 2019 Feb 4.

15.

Polar auxin transport is essential to maintain growth and development of etiolated pea and maize seedlings grown under 1 g conditions: Relevance to the international space station experiment.

Miyamoto K, Inui A, Uheda E, Oka M, Kamada M, Yamazaki C, Shimazu T, Kasahara H, Sano H, Suzuki T, Higashibata A, Ueda J.

Life Sci Space Res (Amst). 2019 Feb;20:1-11. doi: 10.1016/j.lssr.2018.11.001. Epub 2018 Nov 15.

PMID:
30797426
16.

Physical activity and subsequent risk of kidney, bladder and upper urinary tract cancer in the Japanese population: the Japan Public Health Centre-based Prospective Study.

Ihira H, Sawada N, Yamaji T, Goto A, Shimazu T, Inoue M, Iwasaki M, Tsugane S; Japan Public Health Centre-based Prospective Study Group.

Br J Cancer. 2019 Mar;120(5):571-574. doi: 10.1038/s41416-019-0392-y. Epub 2019 Feb 12.

PMID:
30745583
17.

Female reproductive factors and risk of lymphoid neoplasm: The Japan Public Health Center-based Prospective Study.

Tanaka S, Sawada N, Yamaji T, Shimazu T, Goto A, Iwasaki M, Inoue M, Tsugane S; JPHC Study Group.

Cancer Sci. 2019 Apr;110(4):1442-1452. doi: 10.1111/cas.13962. Epub 2019 Mar 9.

18.

The Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT): Study design and participants.

Sawada N, Iwasaki M, Yamaji T, Goto A, Shimazu T, Inoue M, Tanno K, Sakata K, Yamagishi K, Iso H, Yasuda N, Kato T, Saito I, Hasegawa M, Aoyagi K, Tsugane S.

J Epidemiol. 2019 Feb 2. doi: 10.2188/jea.JE20180182. [Epub ahead of print]

19.

Prehospital factors associated with death on hospital arrival after traffic crash in Japan: a national observational study.

Katayama Y, Kitamura T, Kiyohara K, Sado J, Hirose T, Matsuyama T, Kiguchi T, Izawa J, Nakagawa Y, Shimazu T.

BMJ Open. 2019 Jan 29;9(1):e025350. doi: 10.1136/bmjopen-2018-025350.

20.

Lack of social support and social trust as potential risk factors for dry eye disease: JPHC-NEXT study.

Viet Vu CH, Uchino M, Kawashima M, Yuki K, Tsubota K, Nishi A, German CA, Sakata K, Tanno K, Iso H, Yamagishi K, Yasuda N, Saito I, Kato T, Arima K, Tomita Y, Shimazu T, Yamaji T, Goto A, Inoue M, Iwasaki M, Sawada N, Tsugane S; JPHC-NEXT Study Group.

Ocul Surf. 2019 Apr;17(2):278-284. doi: 10.1016/j.jtos.2019.01.005. Epub 2019 Jan 24.

PMID:
30685439
21.

Profile of the ORION (Osaka emergency information Research Intelligent Operation Network system) between 2015 and 2016 in Osaka, Japan: a population-based registry of emergency patients with both ambulance and in-hospital records.

Okamoto J, Katayama Y, Kitamura T, Sado J, Nakamura R, Kimura N, Misaki H, Yamao S, Nakao S, Nitta M, Iwami T, Fujimi S, Kuwagata Y, Shimazu T, Matsuoka T.

Acute Med Surg. 2018 Sep 25;6(1):12-24. doi: 10.1002/ams2.371. eCollection 2019 Jan.

22.

Association between serum liver enzymes and all-cause mortality: The Japan Public Health Center-based Prospective Study.

Yuwaki K, Shimazu T, Yamagiwa Y, Inoue M, Goto A, Yamaji T, Iwasaki M, Sawada N, Tsugane S; JPHC Study Group.

Liver Int. 2018 Dec 19. doi: 10.1111/liv.14030. [Epub ahead of print]

PMID:
30566759
23.

Bone marrow-derived mononuclear cell therapy can attenuate systemic inflammation in rat heatstroke.

Umemura Y, Ogura H, Matsuura H, Ebihara T, Shimizu K, Shimazu T.

Scand J Trauma Resusc Emerg Med. 2018 Nov 16;26(1):97. doi: 10.1186/s13049-018-0566-2.

24.

The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis.

Itai N, Shimazu T, Kimura T, Ibe I, Yamashita R, Kaburagi Y, Dohi T, Tonozuka T, Takao T, Nishikawa A.

PLoS One. 2018 Nov 12;13(11):e0207205. doi: 10.1371/journal.pone.0207205. eCollection 2018.

25.

Cigarette smoking and cervical cancer risk: an evaluation based on a systematic review and meta-analysis among Japanese women.

Sugawara Y, Tsuji I, Mizoue T, Inoue M, Sawada N, Matsuo K, Ito H, Naito M, Nagata C, Kitamura Y, Sadakane A, Tanaka K, Tamakoshi A, Tsugane S, Shimazu T; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

Jpn J Clin Oncol. 2019 Jan 1;49(1):77-86. doi: 10.1093/jjco/hyy158.

PMID:
30407555
26.

Cruciferous vegetable intake and colorectal cancer risk: Japan public health center-based prospective study.

Mori N, Sawada N, Shimazu T, Yamaji T, Goto A, Takachi R, Ishihara J, Iwasaki M, Inoue M, Tsugane S; ; the JPHC Study Group.

Eur J Cancer Prev. 2018 Nov 5. doi: 10.1097/CEJ.0000000000000491. [Epub ahead of print]

PMID:
30399043
27.

The effect of different target temperatures in targeted temperature management on neurologically favorable outcome after out-of-hospital cardiac arrest: A nationwide multicenter observational study in Japan (the JAAM-OHCA registry).

Irisawa T, Matsuyama T, Iwami T, Yamada T, Hayakawa K, Yoshiya K, Noguchi K, Nishimura T, Uejima T, Yagi Y, Kiguchi T, Kishimoto M, Matsuura M, Hayashi Y, Sogabe T, Morooka T, Kitamura T, Shimazu T; CRITICAL Study investigators.

Resuscitation. 2018 Dec;133:82-87. doi: 10.1016/j.resuscitation.2018.10.004. Epub 2018 Oct 11.

PMID:
30316953
28.

Inflammatory projections after focal brain injury trigger neuronal network disruption: An 18F-DPA714 PET study in mice.

Hosomi S, Watabe T, Mori Y, Koyama Y, Adachi S, Hoshi N, Ohnishi M, Ogura H, Yoshioka Y, Hatazawa J, Yamashita T, Shimazu T.

Neuroimage Clin. 2018;20:946-954. doi: 10.1016/j.nicl.2018.09.031. Epub 2018 Oct 1.

29.

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8.

Tsusaka T, Kikuchi M, Shimazu T, Suzuki T, Sohtome Y, Akakabe M, Sodeoka M, Dohmae N, Umehara T, Shinkai Y.

Epigenetics Chromatin. 2018 Oct 4;11(1):56. doi: 10.1186/s13072-018-0231-z.

30.

Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial.

Shimizu K, Yamada T, Ogura H, Mohri T, Kiguchi T, Fujimi S, Asahara T, Yamada T, Ojima M, Ikeda M, Shimazu T.

Crit Care. 2018 Sep 27;22(1):239. doi: 10.1186/s13054-018-2167-x.

31.

Fruit and vegetable intake and pancreatic cancer risk in a population-based cohort study in Japan.

Yamagiwa Y, Sawada N, Shimazu T, Yamaji T, Goto A, Takachi R, Ishihara J, Iwasaki M, Inoue M, Tsugane S.

Int J Cancer. 2019 Apr 15;144(8):1858-1866. doi: 10.1002/ijc.31894. Epub 2018 Oct 30.

PMID:
30255932
32.

The clinical importance of a cytokine network in the acute phase of sepsis.

Matsumoto H, Ogura H, Shimizu K, Ikeda M, Hirose T, Matsuura H, Kang S, Takahashi K, Tanaka T, Shimazu T.

Sci Rep. 2018 Sep 18;8(1):13995. doi: 10.1038/s41598-018-32275-8.

33.

The development of a public health nurses precepting experiential learning scale.

Shimazu T.

Nihon Koshu Eisei Zasshi. 2018;65(8):377-385. doi: 10.11236/jph.65.8_377.

34.

Plasma C-peptide and glycated albumin and subsequent risk of cancer: From a large prospective case-cohort study in Japan.

Hidaka A, Budhathoki S, Yamaji T, Sawada N, Tanaka-Mizuno S, Kuchiba A, Charvat H, Goto A, Shimazu T, Inoue M, Noda M, Tsugane S, Iwasaki M; JPHC Study Group.

Int J Cancer. 2019 Feb 15;144(4):718-729. doi: 10.1002/ijc.31847. Epub 2018 Oct 30.

PMID:
30183080
35.

Fish intake and risk of mortality due to aortic dissection and aneurysm: A pooled analysis of the Japan cohort consortium.

Yamagishi K, Iso H, Shimazu T, Tamakoshi A, Sawada N, Matsuo K, Ito H, Wakai K, Nakayama T, Kitamura Y, Sado J, Tsuji I, Sugawara Y, Mizoue T, Inoue M, Nagata C, Sadakane A, Tanaka K, Tsugane S, Sasazuki S; Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

Clin Nutr. 2019 Aug;38(4):1678-1683. doi: 10.1016/j.clnu.2018.08.007. Epub 2018 Aug 16.

PMID:
30172657
36.

Delay of computed tomography is associated with poor outcome in patients with blunt traumatic aortic injury: A nationwide observational study in Japan.

Katayama Y, Kitamura T, Hirose T, Kiguchi T, Matsuyama T, Sado J, Kiyohara K, Izawa J, Tachino J, Ebihara T, Yoshiya K, Nakagawa Y, Shimazu T.

Medicine (Baltimore). 2018 Aug;97(35):e12112. doi: 10.1097/MD.0000000000012112.

37.

Circumnutational movement in rice coleoptiles involves the gravitropic response: analysis of an agravitropic mutant and space-grown seedlings.

Kobayashi A, Kim HJ, Tomita Y, Miyazawa Y, Fujii N, Yano S, Yamazaki C, Kamada M, Kasahara H, Miyabayashi S, Shimazu T, Fusejima Y, Takahashi H.

Physiol Plant. 2019 Mar;165(3):464-475. doi: 10.1111/ppl.12824. Epub 2018 Oct 2.

PMID:
30159898
38.

Validation of a Blood Biomarker for Identification of Individuals at High Risk for Gastric Cancer.

Epplein M, Butt J, Zhang Y, Hendrix LH, Abnet CC, Murphy G, Zheng W, Shu XO, Tsugane S, Qiao YL, Taylor PR, Shimazu T, Yoo KY, Park SK, Kim J, Jee SH, Waterboer T, Pawlita M, You WC, Pan KF.

Cancer Epidemiol Biomarkers Prev. 2018 Dec;27(12):1472-1479. doi: 10.1158/1055-9965.EPI-18-0582. Epub 2018 Aug 29.

PMID:
30158280
39.

Circulating inflammatory markers and colorectal cancer risk: A prospective case-cohort study in Japan.

Song M, Sasazuki S, Camargo MC, Shimazu T, Charvat H, Yamaji T, Sawada N, Kemp TJ, Pfeiffer RM, Hildesheim A, Pinto LA, Rabkin CS, Tsugane S.

Int J Cancer. 2018 Dec 1;143(11):2767-2776. doi: 10.1002/ijc.31821. Epub 2018 Oct 9.

PMID:
30132835
40.

A familial case of spondyloepiphyseal dysplasia tarda caused by a novel splice site mutation in TRAPPC2.

Fukuma M, Takagi M, Shimazu T, Imamura H, Yagi H, Nishimura G, Hasegawa T.

Clin Pediatr Endocrinol. 2018;27(3):193-196. doi: 10.1297/cpe.27.193. Epub 2018 Jul 31. No abstract available.

41.

Increased Levels of Branched-Chain Amino Acid Associated With Increased Risk of Pancreatic Cancer in a Prospective Case-Control Study of a Large Cohort.

Katagiri R, Goto A, Nakagawa T, Nishiumi S, Kobayashi T, Hidaka A, Budhathoki S, Yamaji T, Sawada N, Shimazu T, Inoue M, Iwasaki M, Yoshida M, Tsugane S.

Gastroenterology. 2018 Nov;155(5):1474-1482.e1. doi: 10.1053/j.gastro.2018.07.033. Epub 2018 Aug 1.

PMID:
30076838
42.

Unveiling epidithiodiketopiperazine as a non-histone arginine methyltransferase inhibitor by chemical protein methylome analyses.

Sohtome Y, Shimazu T, Barjau J, Fujishiro S, Akakabe M, Terayama N, Dodo K, Ito A, Yoshida M, Shinkai Y, Sodeoka M.

Chem Commun (Camb). 2018 Aug 14;54(66):9202-9205. doi: 10.1039/c8cc03907k.

PMID:
30063235
43.

Short-term outcomes of multicenter prospective cohort study of gastric endoscopic resection: 'Real-world evidence' in Japan.

Suzuki H, Takizawa K, Hirasawa T, Takeuchi Y, Ishido K, Hoteya S, Yano T, Tanaka S, Endo M, Nakagawa M, Toyonaga T, Doyama H, Hirasawa K, Matsuda M, Yamamoto H, Fujishiro M, Hashimoto S, Maeda Y, Oyama T, Takenaka R, Yamamoto Y, Naito Y, Michida T, Kobayashi N, Kawahara Y, Hirano M, Jin M, Hori S, Niwa Y, Hikichi T, Shimazu T, Ono H, Tanabe S, Kondo H, Iishi H, Ninomiya M; Ichiro Oda for J-WEB/EGC group.

Dig Endosc. 2019 Jan;31(1):30-39. doi: 10.1111/den.13246. Epub 2018 Sep 25.

PMID:
30058258
44.

Association of prophylactic synbiotics with reduction in diarrhea and pneumonia in mechanically ventilated critically ill patients: A propensity score analysis.

Shimizu K, Ogura H, Kabata D, Shintani A, Tasaki O, Ojima M, Ikeda M, Shimazu T.

J Infect Chemother. 2018 Oct;24(10):795-801. doi: 10.1016/j.jiac.2018.06.006. Epub 2018 Jul 20.

PMID:
30037757
45.

Changes in Smoking Status and Mortality From All Causes and Lung Cancer: A Longitudinal Analysis of a Population-based Study in Japan.

Zha L, Sobue T, Kitamura T, Kitamura Y, Sawada N, Iwasaki M, Sasazuki S, Yamaji T, Shimazu T, Tsugane S.

J Epidemiol. 2019 Jan 5;29(1):11-17. doi: 10.2188/jea.JE20170112. Epub 2018 Jul 21.

46.

Serial change of C1 inhibitor in patients with sepsis: a prospective observational study.

Hirose T, Ogura H, Takahashi H, Ojima M, Jinkoo K, Nakamura Y, Kojima T, Shimazu T.

J Intensive Care. 2018 Jul 4;6:37. doi: 10.1186/s40560-018-0309-5. eCollection 2018.

47.

The profile of Japanese Association for Acute Medicine - out-of-hospital cardiac arrest registry in 2014-2015.

Kitamura T, Iwami T, Atsumi T, Endo T, Kanna T, Kuroda Y, Sakurai A, Tasaki O, Tahara Y, Tsuruta R, Tomio J, Nakata K, Nachi S, Hase M, Hayakawa M, Hiruma T, Hiasa K, Muguruma T, Yano T, Shimazu T, Morimura N; special committee that aims to improve survival after out‐of‐hospital cardiac arrest (OHCA) by providing evidence‐based therapeutic strategy and emergency medical system from the Japanese Association for Acute Medicine (JAAM).

Acute Med Surg. 2018 Apr 25;5(3):249-258. doi: 10.1002/ams2.340. eCollection 2018 Jul.

48.

Female reproductive factors and risk of all-cause and cause-specific mortality among women: The Japan Public Health Center-based Prospective Study (JPHC study).

Otsuki S, Saito E, Sawada N, Abe SK, Hidaka A, Yamaji T, Shimazu T, Goto A, Iwasaki M, Iso H, Mizoue T, Shibuya K, Inoue M, Tsugane S; JPHC Study Group.

Ann Epidemiol. 2018 Sep;28(9):597-604.e6. doi: 10.1016/j.annepidem.2018.06.001. Epub 2018 Jun 15.

PMID:
29960824
49.

Epstein-Barr Virus Antibody Titers Are Not Associated with Gastric Cancer Risk in East Asia.

Varga MG, Cai H, Waterboer T, Murphy G, Shimazu T, Taylor PR, Qiao YL, Park SK, Yoo KY, Jee SH, Cho ER, Kim J, Abnet CC, Tsugane S, Cai Q, Zheng W, Pawlita M, Shu XO, Epplein M.

Dig Dis Sci. 2018 Oct;63(10):2765-2772. doi: 10.1007/s10620-018-5154-9. Epub 2018 Jun 8.

PMID:
29948559
50.

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota.

Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y.

Nat Immunol. 2018 Jul;19(7):755-765. doi: 10.1038/s41590-018-0134-y. Epub 2018 Jun 18.

PMID:
29915298

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