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Items: 1 to 50 of 355

1.

Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes.

Mizunoe Y, Kobayashi M, Hoshino S, Tagawa R, Itagawa R, Hoshino A, Okita N, Sudo Y, Nakagawa Y, Shimano H, Higami Y.

Sci Rep. 2020 Jan 20;10(1):634. doi: 10.1038/s41598-020-57428-6.

2.

Elucidation of Molecular Mechanism of a Selective PPARα Modulator, Pemafibrate, through Combinational Approaches of X-ray Crystallography, Thermodynamic Analysis, and First-Principle Calculations.

Kawasaki M, Kambe A, Yamamoto Y, Arulmozhiraja S, Ito S, Nakagawa Y, Tokiwa H, Nakano S, Shimano H.

Int J Mol Sci. 2020 Jan 6;21(1). pii: E361. doi: 10.3390/ijms21010361.

3.

Transcriptional co-repressor CtBP2 orchestrates epithelial-mesenchymal transition through a novel transcriptional holocomplex with OCT1.

Ma Y, Sekiya M, Kainoh K, Matsuda T, Iwasaki H, Osaki Y, Sugano Y, Suzuki H, Takeuchi Y, Miyamoto T, Yahagi N, Nakagawa Y, Matsuzaka T, Shimano H.

Biochem Biophys Res Commun. 2020 Mar 5;523(2):354-360. doi: 10.1016/j.bbrc.2019.12.070. Epub 2019 Dec 19.

PMID:
31866012
4.

Corrigendum to 'Prosthesis Used in Microvascular Decompressions: A Multicenter Survey in Japan Focusing on Adverse Events' [World Neurosurgery 130 (2019) e251-e258].

Hasegawa M, Hatayama T, Kondo A, Nagahiro S, Fujimaki T, Amagasaki K, Arita K, Date I, Fujii Y, Goto T, Hanaya R, Higuchi Y, Hongo K, Inoue T, Kasuya H, Kayama T, Kawashima M, Kohmura E, Maehara T, Matsushima T, Mizobuchi Y, Morita A, Nishizawa S, Noro S, Saito S, Shimano H, Shirane R, Takeshima H, Tanaka Y, Tanabe H, Toda H, Yamakami I, Nishiyama Y, Ohba S, Hirose Y, Suzuki T.

World Neurosurg. 2020 Feb;134:685. doi: 10.1016/j.wneu.2019.10.081. Epub 2019 Nov 13. No abstract available.

PMID:
31780425
5.

Hepatocyte ELOVL Fatty Acid Elongase 6 Determines Ceramide Acyl-Chain Length and Hepatic Insulin Sensitivity in Mice.

Matsuzaka T, Kuba M, Koyasu S, Yamamoto Y, Motomura K, Arulmozhiraja S, Ohno H, Sharma R, Shimura T, Okajima Y, Han SI, Aita Y, Mizunoe Y, Osaki Y, Iwasaki H, Yatoh S, Suzuki H, Sone H, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Ema M, Takahashi S, Tokiwa H, Shimano H.

Hepatology. 2019 Sep 17. doi: 10.1002/hep.30953. [Epub ahead of print]

PMID:
31529722
6.

Association between Lysosomal Dysfunction and Obesity-Related Pathology: A Key Knowledge to Prevent Metabolic Syndrome.

Mizunoe Y, Kobayashi M, Tagawa R, Nakagawa Y, Shimano H, Higami Y.

Int J Mol Sci. 2019 Jul 27;20(15). pii: E3688. doi: 10.3390/ijms20153688. Review.

7.

Prosthesis Used in Microvascular Decompressions: A Multicenter Survey in Japan Focusing on Adverse Events.

Hasegawa M, Hatayama T, Kondo A, Nagahiro S, Fujimaki T, Amagasaki K, Arita K, Date I, Fujii Y, Goto T, Hanaya R, Higuchi Y, Hongo K, Inoue T, Kasuya H, Kayama T, Kawashima M, Kohmura E, Maehara T, Matsushima T, Mizobuchi Y, Morita A, Nishizawa S, Noro S, Saito S, Shimano H, Shirane R, Takeshima H, Tanaka Y, Tanabe H, Toda H, Yamakami I, Nishiyama Y, Ohba S, Hirose Y, Suzuki T.

World Neurosurg. 2019 Oct;130:e251-e258. doi: 10.1016/j.wneu.2019.06.053. Epub 2019 Jun 14. Erratum in: World Neurosurg. 2020 Feb;134:685.

PMID:
31207376
8.

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Fruchart JC, Santos RD, Aguilar-Salinas C, Aikawa M, Al Rasadi K, Amarenco P, Barter PJ, Ceska R, Corsini A, Després JP, Duriez P, Eckel RH, Ezhov MV, Farnier M, Ginsberg HN, Hermans MP, Ishibashi S, Karpe F, Kodama T, Koenig W, Krempf M, Lim S, Lorenzatti AJ, McPherson R, Nuñez-Cortes JM, Nordestgaard BG, Ogawa H, Packard CJ, Plutzky J, Ponte-Negretti CI, Pradhan A, Ray KK, Reiner Ž, Ridker PM, Ruscica M, Sadikot S, Shimano H, Sritara P, Stock JK, Su TC, Susekov AV, Tartar A, Taskinen MR, Tenenbaum A, Tokgözoğlu LS, Tomlinson B, Tybjærg-Hansen A, Valensi P, Vrablík M, Wahli W, Watts GF, Yamashita S, Yokote K, Zambon A, Libby P.

Cardiovasc Diabetol. 2019 Jun 4;18(1):71. doi: 10.1186/s12933-019-0864-7. Review.

9.

Rho-associated, coiled-coil-containing protein kinase 1 as a new player in the regulation of hepatic lipogenesis.

Miyamoto T, Matsuzaka T, Shimano H.

J Diabetes Investig. 2019 Sep;10(5):1165-1167. doi: 10.1111/jdi.13051. Epub 2019 Apr 19.

10.

Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism.

Sharma R, Matsuzaka T, Kaushik MK, Sugasawa T, Ohno H, Wang Y, Motomura K, Shimura T, Okajima Y, Mizunoe Y, Ma Y, Saber ZM, Iwasaki H, Yatoh S, Suzuki H, Aita Y, Han SI, Takeuchi Y, Yahagi N, Miyamoto T, Sekiya M, Nakagawa Y, Shimano H.

Sci Rep. 2019 Mar 26;9(1):5169. doi: 10.1038/s41598-019-41631-1.

11.

Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice.

Qin R, Murakoshi N, Xu D, Tajiri K, Feng D, Stujanna EN, Yonebayashi S, Nakagawa Y, Shimano H, Nogami A, Koike A, Aonuma K, Ieda M.

Physiol Rep. 2019 Feb;7(4):e13972. doi: 10.14814/phy2.13972.

12.

Glucocorticoid receptor suppresses gene expression of Rev-erbα (Nr1d1) through interaction with the CLOCK complex.

Murayama Y, Yahagi N, Takeuchi Y, Aita Y, Mehrazad Saber Z, Wada N, Li E, Piao X, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Miyamoto T, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.

FEBS Lett. 2019 Feb;593(4):423-432. doi: 10.1002/1873-3468.13328. Epub 2019 Feb 1.

13.

Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.

Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.

JCI Insight. 2019 Jan 10;4(1). pii: 122163. doi: 10.1172/jci.insight.122163. [Epub ahead of print]

14.

Higher pulse pressure predicts initiation of dialysis in Japanese patients with diabetes.

Osawa T, Fujihara K, Harada M, Yamamoto M, Ishizawa M, Suzuki H, Ishiguro H, Matsubayashi Y, Seida H, Yamanaka N, Tanaka S, Shimano H, Kodama S, Sone H.

Diabetes Metab Res Rev. 2019 Mar;35(3):e3120. doi: 10.1002/dmrr.3120. Epub 2019 Jan 16.

PMID:
30578707
15.

Elovl6 regulates mechanical damage-induced keratinocyte death and skin inflammation.

Nakamura Y, Matsuzaka T, Tahara-Hanaoka S, Shibuya K, Shimano H, Nakahashi-Oda C, Shibuya A.

Cell Death Dis. 2018 Dec 5;9(12):1181. doi: 10.1038/s41419-018-1226-1.

16.

Protein Residue Networks from Energetic and Geometric Data: Are They Identical?

Sladek V, Tokiwa H, Shimano H, Shigeta Y.

J Chem Theory Comput. 2018 Dec 11;14(12):6623-6631. doi: 10.1021/acs.jctc.8b00733. Epub 2018 Nov 30.

PMID:
30500196
17.

Network meta-analysis of the relative efficacy of bariatric surgeries for diabetes remission.

Kodama S, Fujihara K, Horikawa C, Harada M, Ishiguro H, Kaneko M, Furukawa K, Matsubayashi Y, Matsunaga S, Shimano H, Tanaka S, Kato K, Sone H.

Obes Rev. 2018 Dec;19(12):1621-1629. doi: 10.1111/obr.12751. Epub 2018 Sep 30. Review.

PMID:
30270528
18.

Relationship between intake of fruit separately from vegetables and triglycerides - A meta-analysis.

Kodama S, Horikawa C, Fujihara K, Ishii D, Hatta M, Takeda Y, Kitazawa M, Matsubayashi Y, Shimano H, Kato K, Tanaka S, Sone H.

Clin Nutr ESPEN. 2018 Oct;27:53-58. doi: 10.1016/j.clnesp.2018.07.001. Epub 2018 Jul 13.

PMID:
30144893
19.

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.

Araki M, Nakagawa Y, Oishi A, Han SI, Wang Y, Kumagai K, Ohno H, Mizunoe Y, Iwasaki H, Sekiya M, Matsuzaka T, Shimano H.

Int J Mol Sci. 2018 Jul 23;19(7). pii: E2148. doi: 10.3390/ijms19072148.

20.

Brg1 regulates pro-lipogenic transcription by modulating SREBP activity in hepatocytes.

Li N, Li M, Hong W, Shao J, Xu H, Shimano H, Lu J, Xu Y.

Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2881-2889. doi: 10.1016/j.bbadis.2018.05.022. Epub 2018 May 30.

21.

Malondialdehyde-modified LDL-related variables are associated with diabetic kidney disease in type 2 diabetes.

Furukawa S, Suzuki H, Fujihara K, Kobayashi K, Iwasaki H, Sugano Y, Yatoh S, Sekiya M, Yahagi N, Shimano H.

Diabetes Res Clin Pract. 2018 Jul;141:237-243. doi: 10.1016/j.diabres.2018.05.019. Epub 2018 May 26.

PMID:
29775676
22.

CREBH Regulates Systemic Glucose and Lipid Metabolism.

Nakagawa Y, Shimano H.

Int J Mol Sci. 2018 May 8;19(5). pii: E1396. doi: 10.3390/ijms19051396. Review.

23.

Evaluation of safety for hepatectomy in a novel mouse model with nonalcoholic-steatohepatitis.

Ozawa Y, Tamura T, Owada Y, Shimizu Y, Kemmochi A, Hisakura K, Matsuzaka T, Shimano H, Isoda H, Ohkohchi N.

World J Gastroenterol. 2018 Apr 21;24(15):1622-1631. doi: 10.3748/wjg.v24.i15.1622.

24.

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.

Ohno H, Matsuzaka T, Tang N, Sharma R, Motomura K, Shimura T, Satoh A, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Nakagawa Y, Sone H, Yahagi N, Yamada N, Higami Y, Shimano H.

Endocrinology. 2018 Jun 1;159(6):2308-2323. doi: 10.1210/en.2017-03179.

PMID:
29668871
25.

Molecular association model of PPARα and its new specific and efficient ligand, pemafibrate: Structural basis for SPPARMα.

Yamamoto Y, Takei K, Arulmozhiraja S, Sladek V, Matsuo N, Han SI, Matsuzaka T, Sekiya M, Tokiwa T, Shoji M, Shigeta Y, Nakagawa Y, Tokiwa H, Shimano H.

Biochem Biophys Res Commun. 2018 May 5;499(2):239-245. doi: 10.1016/j.bbrc.2018.03.135. Epub 2018 Mar 22.

PMID:
29567478
26.

Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.

Karasawa T, Kawashima A, Usui-Kawanishi F, Watanabe S, Kimura H, Kamata R, Shirasuna K, Koyama Y, Sato-Tomita A, Matsuzaka T, Tomoda H, Park SY, Shibayama N, Shimano H, Kasahara T, Takahashi M.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):744-756. doi: 10.1161/ATVBAHA.117.310581. Epub 2018 Feb 8.

PMID:
29437575
27.

Epigenetic modulation of Fgf21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood.

Yuan X, Tsujimoto K, Hashimoto K, Kawahori K, Hanzawa N, Hamaguchi M, Seki T, Nawa M, Ehara T, Kitamura Y, Hatada I, Konishi M, Itoh N, Nakagawa Y, Shimano H, Takai-Igarashi T, Kamei Y, Ogawa Y.

Nat Commun. 2018 Feb 12;9(1):636. doi: 10.1038/s41467-018-03038-w.

28.

Age-dependent changes in dynamic standing-balance ability evaluated quantitatively using a stabilometer.

Suzuki Y, Yatoh S, Suzuki H, Tanabe Y, Shimizu Y, Hada Y, Shimano H.

J Phys Ther Sci. 2018 Jan;30(1):86-91. doi: 10.1589/jpts.30.86. Epub 2018 Jan 27.

29.

A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.

Piao X, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.

FEBS Lett. 2018 Feb;592(3):422-433. doi: 10.1002/1873-3468.12975. Epub 2018 Jan 23.

30.

A Rare Coexistence of Pheochromocytoma and Parkinson's Disease With Diagnostic Challenges.

Matsumura-Matsuda E, Sekiya M, Omoto-Inuzuka M, Santo K, Shikama A, Kuba M, Sugano Y, Iwasaki H, Yatoh S, Sato T, Hara H, Takekoshi K, Suzuki H, Shimano H.

Intern Med. 2018 Apr 1;57(7):979-985. doi: 10.2169/internalmedicine.9242-17. Epub 2017 Dec 21.

31.

Relationships among cardiorespiratory fitness, muscular fitness, and cardiometabolic risk factors in Japanese adolescents: Niigata screening for and preventing the development of non-communicable disease study-Agano (NICE EVIDENCE Study-Agano) 2.

Morikawa SY, Fujihara K, Hatta M, Osawa T, Ishizawa M, Yamamoto M, Furukawa K, Ishiguro H, Matsunaga S, Ogawa Y, Shimano H, Sone H.

Pediatr Diabetes. 2018 Jun;19(4):593-602. doi: 10.1111/pedi.12623. Epub 2017 Dec 19.

PMID:
29266622
32.

Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features.

Owada Y, Tamura T, Tanoi T, Ozawa Y, Shimizu Y, Hisakura K, Matsuzaka T, Shimano H, Nakano N, Sakashita S, Matsukawa T, Isoda H, Ohkohchi N.

Pathol Int. 2018 Jan;68(1):12-22. doi: 10.1111/pin.12612. Epub 2017 Nov 20.

PMID:
29154469
33.

Mitochondrial intermediate peptidase is a novel regulator of sirtuin-3 activation by caloric restriction.

Kobayashi M, Takeda K, Narita T, Nagai K, Okita N, Sudo Y, Miura Y, Tsumoto H, Nakagawa Y, Shimano H, Higami Y.

FEBS Lett. 2017 Dec;591(24):4067-4073. doi: 10.1002/1873-3468.12914. Epub 2017 Nov 28.

34.

Quantitative Relationship Between Cumulative Risk Alleles Based on Genome-Wide Association Studies and Type 2 Diabetes Mellitus: A Systematic Review and Meta-analysis.

Kodama S, Fujihara K, Ishiguro H, Horikawa C, Ohara N, Yachi Y, Tanaka S, Shimano H, Kato K, Hanyu O, Sone H.

J Epidemiol. 2018 Jan 5;28(1):3-18. doi: 10.2188/jea.JE20160151. Epub 2017 Oct 25. Review.

35.

Effect of sodium-glucose cotransporter 2 (SGLT2) inhibition on weight loss is partly mediated by liver-brain-adipose neurocircuitry.

Sawada Y, Izumida Y, Takeuchi Y, Aita Y, Wada N, Li E, Murayama Y, Piao X, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Kadowaki T, Shimano H, Yahagi N.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):40-45. doi: 10.1016/j.bbrc.2017.09.081. Epub 2017 Sep 18.

PMID:
28928093
36.

SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.

Shimano H, Sato R.

Nat Rev Endocrinol. 2017 Dec;13(12):710-730. doi: 10.1038/nrendo.2017.91. Epub 2017 Aug 29. Review.

PMID:
28849786
37.

Association between all-cause mortality and severity of depressive symptoms in patients with type 2 diabetes: Analysis from the Japan Diabetes Complications Study (JDCS).

Matsunaga S, Tanaka S, Fujihara K, Horikawa C, Iimuro S, Kitaoka M, Sato A, Nakamura J, Haneda M, Shimano H, Akanuma Y, Ohashi Y, Sone H.

J Psychosom Res. 2017 Aug;99:34-39. doi: 10.1016/j.jpsychores.2017.05.020. Epub 2017 May 31.

PMID:
28712428
38.

A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling.

Muranaka H, Hayashi A, Minami K, Kitajima S, Kohno S, Nishimoto Y, Nagatani N, Suzuki M, Kulathunga LAN, Sasaki N, Okada N, Matsuzaka T, Shimano H, Tada H, Takahashi C.

Oncogenesis. 2017 Jun 26;6(6):e350. doi: 10.1038/oncsis.2017.51.

39.

Critical role of CREBH-mediated induction of transforming growth factor β2 by hepatitis C virus infection in fibrogenic responses in hepatic stellate cells.

Chida T, Ito M, Nakashima K, Kanegae Y, Aoshima T, Takabayashi S, Kawata K, Nakagawa Y, Yamamoto M, Shimano H, Matsuura T, Kobayashi Y, Suda T, Suzuki T.

Hepatology. 2017 Nov;66(5):1430-1443. doi: 10.1002/hep.29319. Epub 2017 Sep 29.

PMID:
28621467
40.

Elovl6 Deficiency Improves Glycemic Control in Diabetic db/db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity.

Zhao H, Matsuzaka T, Nakano Y, Motomura K, Tang N, Yokoo T, Okajima Y, Han SI, Takeuchi Y, Aita Y, Iwasaki H, Yatoh S, Suzuki H, Sekiya M, Yahagi N, Nakagawa Y, Sone H, Yamada N, Shimano H.

Diabetes. 2017 Jul;66(7):1833-1846. doi: 10.2337/db16-1277. Epub 2017 May 1.

41.

Role of Hormone-sensitive Lipase in Leptin-Promoted Fat Loss and Glucose Lowering.

Takanashi M, Taira Y, Okazaki S, Takase S, Kimura T, Li CC, Xu PF, Noda A, Sakata I, Kumagai H, Ikeda Y, Iizuka Y, Yahagi N, Shimano H, Osuga JI, Ishibashi S, Kadowaki T, Okazaki H.

J Atheroscler Thromb. 2017 Nov 1;24(11):1105-1116. doi: 10.5551/jat.39552. Epub 2017 Apr 12.

42.

Effects of K-877, a novel selective PPARα modulator, on small intestine contribute to the amelioration of hyperlipidemia in low-density lipoprotein receptor knockout mice.

Takei K, Nakagawa Y, Wang Y, Han SI, Satoh A, Sekiya M, Matsuzaka T, Shimano H.

J Pharmacol Sci. 2017 Apr;133(4):214-222. doi: 10.1016/j.jphs.2017.02.003. Epub 2017 Feb 11.

43.

A key role of nuclear factor Y in the refeeding response of fatty acid synthase in adipocytes.

Nishi-Tatsumi M, Yahagi N, Takeuchi Y, Toya N, Takarada A, Murayama Y, Aita Y, Sawada Y, Piao X, Oya Y, Shikama A, Masuda Y, Kubota M, Izumida Y, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Kawakami Y, Kadowaki T, Yamada N, Shimano H.

FEBS Lett. 2017 Apr;591(7):965-978. doi: 10.1002/1873-3468.12620. Epub 2017 Mar 27.

44.

Comparison of baseline characteristics and clinical course in Japanese patients with type 2 diabetes among whom different types of oral hypoglycemic agents were chosen by diabetes specialists as initial monotherapy (JDDM 42).

Fujihara K, Igarashi R, Matsunaga S, Matsubayashi Y, Yamada T, Yokoyama H, Tanaka S, Shimano H, Maegawa H, Yamazaki K, Kawai K, Sone H.

Medicine (Baltimore). 2017 Feb;96(7):e6122. doi: 10.1097/MD.0000000000006122.

45.

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.

Takei K, Han SI, Murayama Y, Satoh A, Oikawa F, Ohno H, Osaki Y, Matsuzaka T, Sekiya M, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Yamada N, Nakagawa Y, Shimano H.

J Diabetes Investig. 2017 Jul;8(4):446-452. doi: 10.1111/jdi.12621. Epub 2017 Apr 25.

46.

Unstable bodyweight and incident type 2 diabetes mellitus: A meta-analysis.

Kodama S, Fujihara K, Ishiguro H, Horikawa C, Ohara N, Yachi Y, Tanaka S, Shimano H, Kato K, Hanyu O, Sone H.

J Diabetes Investig. 2017 Jul;8(4):501-509. doi: 10.1111/jdi.12623. Epub 2017 Apr 26.

47.

SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism.

Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK.

Cell Metab. 2017 Feb 7;25(2):412-427. doi: 10.1016/j.cmet.2016.11.009. Epub 2016 Dec 29.

48.

CREB3L3 controls fatty acid oxidation and ketogenesis in synergy with PPARα.

Nakagawa Y, Satoh A, Tezuka H, Han SI, Takei K, Iwasaki H, Yatoh S, Yahagi N, Suzuki H, Iwasaki Y, Sone H, Matsuzaka T, Yamada N, Shimano H.

Sci Rep. 2016 Dec 16;6:39182. doi: 10.1038/srep39182.

49.

Elongation of Long-Chain Fatty Acid Family Member 6 (Elovl6)-Driven Fatty Acid Metabolism Regulates Vascular Smooth Muscle Cell Phenotype Through AMP-Activated Protein Kinase/Krüppel-Like Factor 4 (AMPK/KLF4) Signaling.

Sunaga H, Matsui H, Anjo S, Syamsunarno MR, Koitabashi N, Iso T, Matsuzaka T, Shimano H, Yokoyama T, Kurabayashi M.

J Am Heart Assoc. 2016 Nov 23;5(12). pii: e004014.

50.

Comparative Binding Analysis of Dipeptidyl Peptidase IV (DPP-4) with Antidiabetic Drugs - An Ab Initio Fragment Molecular Orbital Study.

Arulmozhiraja S, Matsuo N, Ishitsubo E, Okazaki S, Shimano H, Tokiwa H.

PLoS One. 2016 Nov 10;11(11):e0166275. doi: 10.1371/journal.pone.0166275. eCollection 2016.

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