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Items: 1 to 50 of 99

1.

Micro Vacuum Chuck and Tensile Test System for Bio-Mechanical Evaluation of 3D Tissue Constructed of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPS-CM).

Uesugi K, Shima F, Fukumoto K, Hiura A, Tsukamoto Y, Miyagawa S, Sawa Y, Akagi T, Akashi M, Morishima K.

Micromachines (Basel). 2019 Jul 19;10(7). pii: E487. doi: 10.3390/mi10070487.

2.

Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring.

Matsumoto S, Hiraga T, Hayashi Y, Yoshikawa Y, Tsuda C, Araki M, Neya M, Shima F, Kataoka T.

Biochemistry. 2018 Sep 11;57(36):5350-5358. doi: 10.1021/acs.biochem.8b00680. Epub 2018 Aug 30.

PMID:
30141910
3.

Engraftment and morphological development of vascularized human iPS cell-derived 3D-cardiomyocyte tissue after xenotransplantation.

Narita H, Shima F, Yokoyama J, Miyagawa S, Tsukamoto Y, Takamura Y, Hiura A, Fukumoto K, Chiba T, Watanabe S, Sawa Y, Akashi M, Shimoda H.

Sci Rep. 2017 Oct 20;7(1):13708. doi: 10.1038/s41598-017-14053-0.

4.

Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway.

Yoshikawa Y, Takano O, Kato I, Takahashi Y, Shima F, Kataoka T.

Cancer Lett. 2017 Dec 1;410:82-91. doi: 10.1016/j.canlet.2017.09.017. Epub 2017 Sep 23.

PMID:
28951129
5.

Structural transition of solvated H-Ras/GTP revealed by molecular dynamics simulation and local network entropy.

Matsunaga S, Hano Y, Saito Y, Fujimoto KJ, Kumasaka T, Matsumoto S, Kataoka T, Shima F, Tanaka S.

J Mol Graph Model. 2017 Oct;77:51-63. doi: 10.1016/j.jmgm.2017.07.028. Epub 2017 Jul 29.

PMID:
28837923
6.

Fabrication of Orientation-Controlled 3D Tissues Using a Layer-by-Layer Technique and 3D Printed a Thermoresponsive Gel Frame.

Tsukamoto Y, Akagi T, Shima F, Akashi M.

Tissue Eng Part C Methods. 2017 Jun;23(6):357-366. doi: 10.1089/ten.TEC.2017.0134. Epub 2017 Jun 5.

PMID:
28471308
7.

Construction and histological analysis of a 3D human arterial wall model containing vasa vasorum using a layer-by-layer technique.

Shima F, Narita H, Hiura A, Shimoda H, Akashi M.

J Biomed Mater Res A. 2017 Mar;105(3):814-823. doi: 10.1002/jbm.a.35942. Epub 2016 Nov 22.

PMID:
27779830
8.

Integrin-α10 Dependency Identifies RAC and RICTOR as Therapeutic Targets in High-Grade Myxofibrosarcoma.

Okada T, Lee AY, Qin LX, Agaram N, Mimae T, Shen Y, O'Connor R, López-Lago MA, Craig A, Miller ML, Agius P, Molinelli E, Socci ND, Crago AM, Shima F, Sander C, Singer S.

Cancer Discov. 2016 Oct;6(10):1148-1165. Epub 2016 Aug 30.

9.

Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal.

Matsumoto S, Miyano N, Baba S, Liao J, Kawamura T, Tsuda C, Takeda A, Yamamoto M, Kumasaka T, Kataoka T, Shima F.

Sci Rep. 2016 May 16;6:25931. doi: 10.1038/srep25931.

10.

Current status of the development of Ras inhibitors.

Shima F, Matsumoto S, Yoshikawa Y, Kawamura T, Isa M, Kataoka T.

J Biochem. 2015 Aug;158(2):91-9. doi: 10.1093/jb/mvv060. Epub 2015 Jun 22. Review.

PMID:
26100833
11.

Effect of Hydrophobic Side Chains in the Induction of Immune Responses by Nanoparticle Adjuvants Consisting of Amphiphilic Poly(γ-glutamic acid).

Shima F, Akagi T, Akashi M.

Bioconjug Chem. 2015 May 20;26(5):890-8. doi: 10.1021/acs.bioconjchem.5b00106. Epub 2015 Apr 17.

PMID:
25865284
12.

Seroprevalence and risk factors of brucellosis in goats in selected states in Nigeria and the public health implications.

Ogugua AJ, Akinseye VO, Ayoola MC, Oyesola OO, Shima FK, Tijjani AO, Musa AN, Adesokan HK, Perrett L, Taylor A, Stack JA, Moriyon I, Cadmus SI.

Afr J Med Med Sci. 2014 Sep;43(Suppl 1):121-129.

13.

The role of hydrophobicity in the disruption of erythrocyte membrane by nanoparticles composed of hydrophobically modified poly(γ-glutamic acid).

Shima F, Akagi T, Akashi M.

J Biomater Sci Polym Ed. 2014;25(2):203-10. doi: 10.1080/09205063.2013.848328. Epub 2013 Oct 18.

PMID:
24134678
14.

Manipulating the antigen-specific immune response by the hydrophobicity of amphiphilic poly(γ-glutamic acid) nanoparticles.

Shima F, Akagi T, Uto T, Akashi M.

Biomaterials. 2013 Dec;34(37):9709-16. doi: 10.1016/j.biomaterials.2013.08.064. Epub 2013 Sep 7.

PMID:
24016848
15.

[On-the-street DOTS for a homeless tuberculosis patient--case report of a patient who had difficulties with TB treatment adherence].

Saito R, Takao Y, Fukazawa K, Ohmori M, Nagamine M, Shima F, Kaguraoka S, Fukuuchi K, Ishikawa N.

Kekkaku. 2013 Apr;88(4):429-37. Japanese.

PMID:
23819320
16.

Size effect of amphiphilic poly(γ-glutamic acid) nanoparticles on cellular uptake and maturation of dendritic cells in vivo.

Shima F, Uto T, Akagi T, Baba M, Akashi M.

Acta Biomater. 2013 Nov;9(11):8894-901. doi: 10.1016/j.actbio.2013.06.010. Epub 2013 Jun 14.

PMID:
23770225
17.

Synergistic stimulation of antigen presenting cells via TLR by combining CpG ODN and poly(γ-glutamic acid)-based nanoparticles as vaccine adjuvants.

Shima F, Uto T, Akagi T, Akashi M.

Bioconjug Chem. 2013 Jun 19;24(6):926-33. doi: 10.1021/bc300611b. Epub 2013 May 13.

PMID:
23631730
18.

In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.

Shima F, Yoshikawa Y, Ye M, Araki M, Matsumoto S, Liao J, Hu L, Sugimoto T, Ijiri Y, Takeda A, Nishiyama Y, Sato C, Muraoka S, Tamura A, Osoda T, Tsuda K, Miyakawa T, Fukunishi H, Shimada J, Kumasaka T, Yamamoto M, Kataoka T.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. doi: 10.1073/pnas.1217730110. Epub 2013 Apr 29.

19.

Discovery of small-molecule Ras inhibitors that display antitumor activity by interfering with Ras·GTP-effector interaction.

Shima F, Yoshikawa Y, Matsumoto S, Kataoka T.

Enzymes. 2013;34 Pt. B:1-23. doi: 10.1016/B978-0-12-420146-0.00001-9. Epub 2013 Nov 7. Review.

PMID:
25034098
20.

Uptake of biodegradable poly(γ-glutamic acid) nanoparticles and antigen presentation by dendritic cells in vivo.

Uto T, Toyama M, Nishi Y, Akagi T, Shima F, Akashi M, Baba M.

Results Immunol. 2012 Dec 3;3:1-9. doi: 10.1016/j.rinim.2012.11.002. eCollection 2013.

21.

Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants.

Muraoka S, Shima F, Araki M, Inoue T, Yoshimoto A, Ijiri Y, Seki N, Tamura A, Kumasaka T, Yamamoto M, Kataoka T.

FEBS Lett. 2012 Jun 12;586(12):1715-8. doi: 10.1016/j.febslet.2012.04.058. Epub 2012 May 11.

22.

Solution structure of the state 1 conformer of GTP-bound H-Ras protein and distinct dynamic properties between the state 1 and state 2 conformers.

Araki M, Shima F, Yoshikawa Y, Muraoka S, Ijiri Y, Nagahara Y, Shirono T, Kataoka T, Tamura A.

J Biol Chem. 2011 Nov 11;286(45):39644-53. doi: 10.1074/jbc.M111.227074. Epub 2011 Sep 19.

23.

Comparative activity of biodegradable nanoparticles with aluminum adjuvants: antigen uptake by dendritic cells and induction of immune response in mice.

Uto T, Akagi T, Toyama M, Nishi Y, Shima F, Akashi M, Baba M.

Immunol Lett. 2011 Oct 30;140(1-2):36-43. doi: 10.1016/j.imlet.2011.06.002. Epub 2011 Jun 12.

PMID:
21693134
24.

Intracellular degradation and distribution of protein-encapsulated amphiphilic poly(amino acid) nanoparticles.

Akagi T, Shima F, Akashi M.

Biomaterials. 2011 Jul;32(21):4959-67. doi: 10.1016/j.biomaterials.2011.03.049. Epub 2011 Apr 11.

PMID:
21482432
25.

Critical roles of interactions among switch I-preceding residues and between switch II and its neighboring alpha-helix in conformational dynamics of the GTP-bound Ras family small GTPases.

Matsumoto K, Shima F, Muraoka S, Araki M, Hu L, Ijiri Y, Hirai R, Liao J, Yoshioka T, Kumasaka T, Yamamoto M, Tamura A, Kataoka T.

J Biol Chem. 2011 Apr 29;286(17):15403-12. doi: 10.1074/jbc.M110.204933. Epub 2011 Mar 9.

26.

[A high school measles outbreak--control measures and vaccine efficacy].

Tokuda K, Ikarashi M, Yamamoto KU, Taya KT, Nakashima K, Nakanishi Y, Shima F, Teranishi A, Taniguchi K, Okabe N.

Kansenshogaku Zasshi. 2010 Nov;84(6):714-20. Japanese.

PMID:
21226323
27.

Structural basis for conformational dynamics of GTP-bound Ras protein.

Shima F, Ijiri Y, Muraoka S, Liao J, Ye M, Araki M, Matsumoto K, Yamamoto N, Sugimoto T, Yoshikawa Y, Kumasaka T, Yamamoto M, Tamura A, Kataoka T.

J Biol Chem. 2010 Jul 16;285(29):22696-705. doi: 10.1074/jbc.M110.125161. Epub 2010 May 17.

28.

Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome.

Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):439-42. doi: 10.1016/j.bbrc.2009.02.087. Epub 2009 Feb 21.

PMID:
19236846
29.

Direct localization of subthalamic nucleus supplemented by single-track electrophysiological guidance in deep brain stimulation lead implantation: techniques and clinical results.

Koike Y, Shima F, Nakamizo A, Miyagi Y.

Stereotact Funct Neurosurg. 2008;86(3):173-8. doi: 10.1159/000120430. Epub 2008 Mar 12.

PMID:
18334860
30.

Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics.

Liao J, Shima F, Araki M, Ye M, Muraoka S, Sugimoto T, Kawamura M, Yamamoto N, Tamura A, Kataoka T.

Biochem Biophys Res Commun. 2008 May 2;369(2):327-32. doi: 10.1016/j.bbrc.2008.01.169. Epub 2008 Feb 20.

PMID:
18291096
31.

Brain shift: an error factor during implantation of deep brain stimulation electrodes.

Miyagi Y, Shima F, Sasaki T.

J Neurosurg. 2007 Nov;107(5):989-97.

PMID:
17977272
32.

Mechanical injury of the subthalamic area during stereotactic surgery followed by improvement of trunk, neck, and face tremor--case report--.

Hirashima Y, Ikeda H, Asahi T, Shibata T, Noguchi K, Shima F, Endo S.

Neurol Med Chir (Tokyo). 2005 Sep;45(9):484-6.

33.

[Critical role of posttranslational modification of Ras proteins in effector activation].

Shima F, Kataoka T.

Seikagaku. 2005 Jun;77(6):519-26. Review. Japanese. No abstract available.

PMID:
16022428
34.

Crystal structure of M-Ras reveals a GTP-bound "off" state conformation of Ras family small GTPases.

Ye M, Shima F, Muraoka S, Liao J, Okamoto H, Yamamoto M, Tamura A, Yagi N, Ueki T, Kataoka T.

J Biol Chem. 2005 Sep 2;280(35):31267-75. Epub 2005 Jun 30.

35.

Direct activation of fission yeast adenylyl cyclase by heterotrimeric G protein gpa2.

Ogihara H, Shima F, Naito K, Asato T, Kariya K, Kataoka T.

Kobe J Med Sci. 2004;50(3-4):111-21.

36.

Inferior temporal sulcus approach for amygdalohippocampectomy guided by a laser beam of stereotactic navigator.

Miyagi Y, Shima F, Ishido K, Araki T, Taniwaki Y, Okamoto I, Kamikaseda K.

Neurosurgery. 2003 May;52(5):1117-23; discussion 1123-4.

PMID:
12699556
37.

Implantation of deep brain stimulation electrodes in unshaved patients. Technical note.

Miyagi Y, Shima F, Ishido K.

J Neurosurg. 2002 Dec;97(6):1476-8.

PMID:
12507152
38.

Localization of epileptogenic zone in temporal lobe epilepsy by ictal scalp EEG.

Sakai Y, Nagano H, Sakata A, Kinoshita S, Hamasaki N, Shima F, Morioka T.

Seizure. 2002 Apr;11(3):163-8.

39.

Inferior temporal sulcus as a site of corticotomy: magnetic resonance imaging analysis of individual sulcus patterns.

Miyagi Y, Shima F, Ishido K, Araki T, Kamikaseda K.

Neurosurgery. 2001 Dec;49(6):1394-7; discussion 1397-8.

PMID:
11846939
40.

Pleomorphic xanthoastrocytoma with predominantly exophytic growth: case report.

Miyagi Y, Suzuki SO, Iwaki T, Shima F, Ishido K, Araki T, Kamikaseda K.

Surg Neurol. 2001 Nov;56(5):330-2. No abstract available.

PMID:
11750009
41.

Critical function of the Ras-associating domain as a primary Ras-binding site for regulation of Saccharomyces cerevisiae adenylyl cyclase.

Kido M, Shima F, Satoh T, Asato T, Kariya K, Kataoka T.

J Biol Chem. 2002 Feb 1;277(5):3117-23. Epub 2001 Nov 26.

42.

Role of Raf-1 conserved region 2 in regulation of Ras-dependent Raf-1 activation.

Sendoh H, Hu CD, Wu D, Song C, Yamawaki-Kataoka Y, Kotani J, Okada T, Shima F, Kariya K, Kataoka T.

Biochem Biophys Res Commun. 2000 May 19;271(3):596-602.

PMID:
10814507
43.

Association of yeast adenylyl cyclase with cyclase-associated protein CAP forms a second Ras-binding site which mediates its Ras-dependent activation.

Shima F, Okada T, Kido M, Sen H, Tanaka Y, Tamada M, Hu CD, Yamawaki-Kataoka Y, Kariya K, Kataoka T.

Mol Cell Biol. 2000 Jan;20(1):26-33.

44.

Posteroventral pallidotomy for midbrain tremor after a pontine hemorrhage. Case report.

Miyagi Y, Shima F, Ishido K, Moriguchi M, Kamikaseda K.

J Neurosurg. 1999 Nov;91(5):885-8.

PMID:
10541252
45.

Tremor induced by toluene misuse successfully treated by a Vim thalamotomy.

Miyagi Y, Shima F, Ishido K, Yasutake T, Kamikaseda K.

J Neurol Neurosurg Psychiatry. 1999 Jun;66(6):794-6.

46.

Characterization of a novel Ras-binding protein Ce-FLI-1 comprising leucine-rich repeats and gelsolin-like domains.

Goshima M, Kariya K, Yamawaki-Kataoka Y, Okada T, Shibatohge M, Shima F, Fujimoto E, Kataoka T.

Biochem Biophys Res Commun. 1999 Apr 2;257(1):111-6.

PMID:
10092519
47.

Coiled-coil interaction of N-terminal 36 residues of cyclase-associated protein with adenylyl cyclase is sufficient for its function in Saccharomyces cerevisiae ras pathway.

Nishida Y, Shima F, Sen H, Tanaka Y, Yanagihara C, Yamawaki-Kataoka Y, Kariya K, Kataoka T.

J Biol Chem. 1998 Oct 23;273(43):28019-24.

48.

[A support system after the health examination for the aged].

Tukada H, Shima F, Fukunaga H, Sato E, Fujiyama Y.

Nihon Koshu Eisei Zasshi. 1997 Dec;44(12):977-82. Japanese. No abstract available.

PMID:
9553387
49.

Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.

Shibatohge M, Kariya Ki, Liao Y, Hu CD, Watari Y, Goshima M, Shima F, Kataoka T.

J Biol Chem. 1998 Mar 13;273(11):6218-22.

50.

Visual evoked potentials in the vicinity of the optic tract during stereotactic pallidotomy.

Tobimatsu S, Shima F, Ishido K, Kato M.

Electroencephalogr Clin Neurophysiol. 1997 May;104(3):274-9.

PMID:
9186242

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