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Items: 21

1.

Airway pathological heterogeneity in asthma: Visualization of disease microclusters using topological data analysis.

Siddiqui S, Shikotra A, Richardson M, Doran E, Choy D, Bell A, Austin CD, Eastham-Anderson J, Hargadon B, Arron JR, Wardlaw A, Brightling CE, Heaney LG, Bradding P.

J Allergy Clin Immunol. 2018 Nov;142(5):1457-1468. doi: 10.1016/j.jaci.2017.12.982. Epub 2018 Mar 14.

PMID:
29550052
2.

Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q.

Lal N, Willcox CR, Beggs A, Taniere P, Shikotra A, Bradding P, Adams R, Fisher D, Middleton G, Tselepis C, Willcox BE.

J Pathol Clin Res. 2017 Jul 14;3(3):155-170. doi: 10.1002/cjp2.70. eCollection 2017 Jul.

3.

Associations in asthma between quantitative computed tomography and bronchial biopsy-derived airway remodelling.

Berair R, Hartley R, Mistry V, Sheshadri A, Gupta S, Singapuri A, Gonem S, Marshall RP, Sousa AR, Shikotra A, Kay R, Wardlaw A, Bradding P, Siddiqui S, Castro M, Brightling CE.

Eur Respir J. 2017 May 1;49(5). pii: 1601507. doi: 10.1183/13993003.01507-2016. Print 2017 May.

4.

A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma.

Shikotra A, Choy DF, Siddiqui S, Arthur G, Nagarkar DR, Jia G, Wright AK, Ohri CM, Doran E, Butler CA, Hargadon B, Abbas AR, Jackman J, Wu LC, Heaney LG, Arron JR, Bradding P.

J Immunol. 2017 Apr 15;198(8):3307-3317. doi: 10.4049/jimmunol.1600606. Epub 2017 Mar 8.

5.

Mast cell phenotype, TNFα expression and degranulation status in non-small cell lung cancer.

Shikotra A, Ohri CM, Green RH, Waller DA, Bradding P.

Sci Rep. 2016 Dec 6;6:38352. doi: 10.1038/srep38352.

6.

CD48 on blood leukocytes and in serum of asthma patients varies with severity.

Gangwar RS, Minai-Fleminger Y, Seaf M, Gutgold A, Shikotra A, Barber C, Chauhan A, Holgate S, Bradding P, Howarth P, Eliashar R, Berkman N, Levi-Schaffer F.

Allergy. 2017 Jun;72(6):888-895. doi: 10.1111/all.13082. Epub 2016 Dec 1. Erratum in: Allergy. 2017 Oct;72 (10 ):1591.

PMID:
27859399
7.

Reduced epithelial suppressor of cytokine signalling 1 in severe eosinophilic asthma.

Doran E, Choy DF, Shikotra A, Butler CA, O'Rourke DM, Johnston JA, Kissenpfennig A, Bradding P, Arron JR, Heaney LG.

Eur Respir J. 2016 Sep;48(3):715-25. doi: 10.1183/13993003.00400-2015. Epub 2016 Jun 23.

8.

KCa3.1 K+ Channel Expression and Function in Human Bronchial Epithelial Cells.

Arthur GK, Duffy SM, Roach KM, Hirst RA, Shikotra A, Gaillard EA, Bradding P.

PLoS One. 2015 Dec 21;10(12):e0145259. doi: 10.1371/journal.pone.0145259. eCollection 2015.

9.

TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.

Choy DF, Hart KM, Borthwick LA, Shikotra A, Nagarkar DR, Siddiqui S, Jia G, Ohri CM, Doran E, Vannella KM, Butler CA, Hargadon B, Sciurba JC, Gieseck RL, Thompson RW, White S, Abbas AR, Jackman J, Wu LC, Egen JG, Heaney LG, Ramalingam TR, Arron JR, Wynn TA, Bradding P.

Sci Transl Med. 2015 Aug 19;7(301):301ra129. doi: 10.1126/scitranslmed.aab3142.

PMID:
26290411
10.

Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells.

Gough KC, Maddison BC, Shikotra A, Moiseeva EP, Yang W, Jarvis S, Bradding P.

Respir Res. 2015 Jul 15;16:86. doi: 10.1186/s12931-015-0245-z.

11.

The role of tissue eosinophils in asthmatic airway remodelling.

Shikotra A, Siddiqui S.

Clin Exp Allergy. 2013 Dec;43(12):1302-6. doi: 10.1111/cea.12204. No abstract available.

PMID:
24261942
12.

Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells.

Chachi L, Shikotra A, Duffy SM, Tliba O, Brightling C, Bradding P, Amrani Y.

J Immunol. 2013 Sep 1;191(5):2624-2636. doi: 10.4049/jimmunol.1300104. Epub 2013 Jul 31.

13.

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients.

Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV, Woodruff PG, Harris JM, Arron JR; Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) Study Group.

J Allergy Clin Immunol. 2012 Sep;130(3):647-654.e10. doi: 10.1016/j.jaci.2012.06.025. Epub 2012 Aug 1.

14.

Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma.

Shikotra A, Choy DF, Ohri CM, Doran E, Butler C, Hargadon B, Shelley M, Abbas AR, Austin CD, Jackman J, Wu LC, Heaney LG, Arron JR, Bradding P.

J Allergy Clin Immunol. 2012 Jan;129(1):104-11.e1-9. doi: 10.1016/j.jaci.2011.08.031. Epub 2011 Oct 5.

PMID:
21975173
15.

The tissue microlocalisation and cellular expression of CD163, VEGF, HLA-DR, iNOS, and MRP 8/14 is correlated to clinical outcome in NSCLC.

Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P.

PLoS One. 2011;6(7):e21874. doi: 10.1371/journal.pone.0021874. Epub 2011 Jul 22. Erratum in: PLoS One. 6(12). doi: 10.1371/annotation/2088e0ac-4cdb-442d-9259-062f582e8097.

16.

Physical interactions between mast cells and eosinophils: a novel mechanism enhancing eosinophil survival in vitro.

Elishmereni M, Alenius HT, Bradding P, Mizrahi S, Shikotra A, Minai-Fleminger Y, Mankuta D, Eliashar R, Zabucchi G, Levi-Schaffer F.

Allergy. 2011 Mar;66(3):376-85. doi: 10.1111/j.1398-9995.2010.02494.x. Epub 2010 Oct 26.

PMID:
20977491
17.

Tumour necrosis factor-alpha expression in tumour islets confers a survival advantage in non-small cell lung cancer.

Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P.

BMC Cancer. 2010 Jun 23;10:323. doi: 10.1186/1471-2407-10-323.

18.

Chemokine receptor expression in tumour islets and stroma in non-small cell lung cancer.

Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P.

BMC Cancer. 2010 Apr 29;10:172. doi: 10.1186/1471-2407-10-172.

19.

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival.

Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P.

Eur Respir J. 2009 Jan;33(1):118-26. doi: 10.1183/09031936.00065708.

20.

Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis.

Siddiqui S, Sutcliffe A, Shikotra A, Woodman L, Doe C, McKenna S, Wardlaw A, Bradding P, Pavord I, Brightling C.

J Allergy Clin Immunol. 2007 Oct;120(4):813-9. Epub 2007 Jul 5.

PMID:
17610943
21.

Characterization of the ectodomain shedding of the beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).

Hussain I, Hawkins J, Shikotra A, Riddell DR, Faller A, Dingwall C.

J Biol Chem. 2003 Sep 19;278(38):36264-8. Epub 2003 Jul 11.

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