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Distinct immunoglobulin heavy chain variable region gene repertoire and lower frequency of del(11q) in Taiwanese patients with chronic lymphocytic leukaemia.

Huang YJ, Kuo MC, Chang H, Wang PN, Wu JH, Huang YM, Ma MC, Tang TC, Kuo CY, Shih LY.

Br J Haematol. 2019 Jun 23. doi: 10.1111/bjh.16051. [Epub ahead of print]


Combined serum biomarkers in the noninvasive diagnosis of complicated parapneumonic effusions and empyema.

Wu KA, Wu CC, Liu YC, Hsueh PC, Chin CY, Wang CL, Chu CM, Shih LJ, Yang CY.

BMC Pulm Med. 2019 Jun 18;19(1):108. doi: 10.1186/s12890-019-0877-8.


Cutaneous involvement of polymorphic post-transplant lymphoproliferative disorder in a child after liver transplantation.

Chen KY, Lin CY, Kuo TT, Shih LY, Chang CH, Chen WT, Yang CY.

Pediatr Dermatol. 2019 Jun 18. doi: 10.1111/pde.13903. [Epub ahead of print]


Does public report card matter? A 10-year interrupted time series analysis on total knee replacement.

Chen TT, Hsueh YA, Liaw CK, Shih LN, Huang LY.

Eur J Public Health. 2019 Jun 9. pii: ckz112. doi: 10.1093/eurpub/ckz112. [Epub ahead of print]


Urinary Trypsinogen-2 Level Predicts Local Complications of Acute Pancreatitis.

Wu HC, Wang HP, Chen CC, Wu CH, Liu TH, Wang CH, Shih LN, Liao WC.

J Gastroenterol Hepatol. 2019 Apr 30. doi: 10.1111/jgh.14698. [Epub ahead of print]


Ets1 Plays a Critical Role in MLL/EB1-Mediated Leukemic Transformation in a Mouse Bone Marrow Transplantation Model.

Fu JF, Yen TH, Huang YJ, Shih LY.

Neoplasia. 2019 May;21(5):469-481. doi: 10.1016/j.neo.2019.03.006. Epub 2019 Apr 8.


Review of "The Challenge of Measuring Surgeon Spending for Payment Policies" by VonAchen P et al in Ann Surg 268: 903-907, 2018.

Shih L, Hollier LH Jr.

J Craniofac Surg. 2019 Apr 2. doi: 10.1097/SCS.0000000000005406. [Epub ahead of print] No abstract available.


Synchronous vascular endothelial growth factor protein profiles in both tissue and serum identify metastasis and poor survival in colorectal cancer.

Yeh CC, Shih LJ, Chang JL, Tsuei YW, Wu CC, Hsiao CW, Chuu CP, Kao YH.

Sci Rep. 2019 Mar 12;9(1):4228. doi: 10.1038/s41598-019-40862-6.


Translational methods to detect asymmetries in temporal and spatial walking metrics in parkinsonian mouse models and human subjects with Parkinson's disease.

Broom L, Worley A, Gao F, Hernandez LD, Ashton CE, Shih LC, VanderHorst VG.

Sci Rep. 2019 Feb 21;9(1):2437. doi: 10.1038/s41598-019-38623-6.


Sedoheptulose-1,7-bisphospate Accumulation and Metabolic Anomalies in Hepatoma Cells Exposed to Oxidative Stress.

Cheng ML, Lin JF, Huang CY, Li GJ, Shih LM, Chiu DT, Ho HY.

Oxid Med Cell Longev. 2019 Jan 13;2019:5913635. doi: 10.1155/2019/5913635. eCollection 2019.


TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

Haase D, Stevenson KE, Neuberg D, Maciejewski JP, Nazha A, Sekeres MA, Ebert BL, Garcia-Manero G, Haferlach C, Haferlach T, Kern W, Ogawa S, Nagata Y, Yoshida K, Graubert TA, Walter MJ, List AF, Komrokji RS, Padron E, Sallman D, Papaemmanuil E, Campbell PJ, Savona MR, Seegmiller A, Adès L, Fenaux P, Shih LY, Bowen D, Groves MJ, Tauro S, Fontenay M, Kosmider O, Bar-Natan M, Steensma D, Stone R, Heuser M, Thol F, Cazzola M, Malcovati L, Karsan A, Ganster C, Hellström-Lindberg E, Boultwood J, Pellagatti A, Santini V, Quek L, Vyas P, Tüchler H, Greenberg PL, Bejar R; International Working Group for MDS Molecular Prognostic Committee.

Leukemia. 2019 Jan 11. doi: 10.1038/s41375-018-0351-2. [Epub ahead of print]


The Clinical Course of Idiopathic Bilateral Vocal Fold Motion Impairment in Adults: Case Series and Review of the Literature.

Abu Ghanem S, Junlapan A, Tsai SW, Shih LC, Sung CK, Damrose EJ.

J Voice. 2018 Dec 4. pii: S0892-1997(18)30441-7. doi: 10.1016/j.jvoice.2018.11.012. [Epub ahead of print]


Contribution of MMP2 Promoter Genotypes to Oral Cancer Susceptibility, Recurrence and Metastasis in Taiwan.

Tsai CW, Hsu HM, Wang YC, Chang WS, Shih LC, Sun KT, Hung YW, Yang YC, Gong CL, Bau DT.

Anticancer Res. 2018 Dec;38(12):6821-6826. doi: 10.21873/anticanres.13055.


Stable Isotope-Labeled Lipidomics to Unravel the Heterogeneous Development Lipotoxicity.

Shih LM, Tang HY, Lynn KS, Huang CY, Ho HY, Cheng ML.

Molecules. 2018 Nov 2;23(11). pii: E2862. doi: 10.3390/molecules23112862.


Comparison of the Fahn-Tolosa-Marin Clinical Rating Scale and the Essential Tremor Rating Assessment Scale.

Ondo W, Hashem V, LeWitt PA, Pahwa R, Shih L, Tarsy D, Zesiewicz T, Elble R.

Mov Disord Clin Pract. 2017 Nov 23;5(1):60-65. doi: 10.1002/mdc3.12560. eCollection 2018 Jan-Feb.


Early Injection Laryngoplasty After Surgery: 30 Cases and Proposed Aspiration Assessment Protocol.

Abu-Ghanem S, Rudy S, Deane S, Tsai SW, Shih LC, Damrose EJ, Sung CK.

J Voice. 2018 Oct 16. pii: S0892-1997(18)30313-8. doi: 10.1016/j.jvoice.2018.08.011. [Epub ahead of print]


Neck Lymph Node Metastasis as A Poor Prognostic Factor in Thoracic Esophageal Squamous Cell Carcinoma Patients Receiving Concurrent Chemoradiotherapy: A Propensity Score-Matched Analysis.

Chen YH, Lu HI, Lo CM, Wang YM, Chou SY, Hsiao CC, Shih LH, Chen SW, Li SH.

Sci Rep. 2018 Oct 10;8(1):15073. doi: 10.1038/s41598-018-33400-3.


Clinical and biological relevance of genetic alterations in pediatric T-cell acute lymphoblastic leukemia in Taiwan.

Yeh TC, Liang DC, Liu HC, Jaing TH, Chen SH, Hou JY, Yang CP, Huang YJ, Yao HW, Huang TY, Lin TH, Shih LY.

Pediatr Blood Cancer. 2019 Jan;66(1):e27496. doi: 10.1002/pbc.27496. Epub 2018 Oct 2.


CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia.

Chiang YJ, Liao WT, Ho KC, Wang SH, Chen YG, Ho CL, Huang SF, Shih LY, Yang-Yen HF, Yen JJ.

Oncogene. 2019 Feb;38(9):1432-1447. doi: 10.1038/s41388-018-0507-6. Epub 2018 Sep 28.


Genetic and Epigenetic Perturbations by DNMT3A-R882 Mutants Impaired Apoptosis through Augmentation of PRDX2 in Myeloid Leukemia Cells.

Bera R, Chiu MC, Huang YJ, Liang DC, Lee YS, Shih LY.

Neoplasia. 2018 Nov;20(11):1106-1120. doi: 10.1016/j.neo.2018.08.013. Epub 2018 Sep 21.


Bioimaging of alloantigen-stimulated regulatory T cells in rat vascularized composite allotransplantation.

Cheng HY, Tay SKL, Wen CJ, Lin CF, Wang AY, Shih LY, Liu SC, Kobayashi E, Lin CH, Wei FC.

PLoS One. 2018 Sep 7;13(9):e0203624. doi: 10.1371/journal.pone.0203624. eCollection 2018.


Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes.

Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G.

Cancer Discov. 2018 Nov;8(11):1438-1457. doi: 10.1158/2159-8290.CD-17-1203. Epub 2018 Aug 23.


Training Effects of Visual Stroboscopic Impairment on Surgical Performance: A Randomized-Controlled Trial.

Zavlin D, Chegireddy V, Nguyen-Lee JJ, Shih L, Nia AM, Friedman JD, Echo A.

J Surg Educ. 2019 Mar - Apr;76(2):560-567. doi: 10.1016/j.jsurg.2018.07.018. Epub 2018 Aug 18.


The crucial role of blood VEGF kinetics in patients with locally advanced esophageal squamous cell carcinoma receiving curative concurrent chemoradiotherapy.

Chen YH, Lu HI, Lo CM, Wang YM, Chou SY, Hsiao CC, Huang CC, Shih LH, Chen SW, Li SH.

BMC Cancer. 2018 Aug 20;18(1):837. doi: 10.1186/s12885-018-4731-9.


ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion.

Madan V, Han L, Hattori N, Teoh WW, Mayakonda A, Sun QY, Ding LW, Nordin HBM, Lim SL, Shyamsunder P, Dakle P, Sundaresan J, Doan NB, Sanada M, Sato-Otsubo A, Meggendorfer M, Yang H, Said JW, Ogawa S, Haferlach T, Liang DC, Shih LY, Nakamaki T, Wang QT, Koeffler HP.

Haematologica. 2018 Dec;103(12):1980-1990. doi: 10.3324/haematol.2018.189928. Epub 2018 Aug 9.


Identifying therapeutic targets from spontaneous beneficial brain lesions.

Joutsa J, Shih LC, Horn A, Reich MM, Wu O, Rost NS, Fox MD.

Ann Neurol. 2018 Jul;84(1):153-157. doi: 10.1002/ana.25285.


Bortezomib-based therapy for transplant-ineligible East Asian patients with newly diagnosed mantle-cell lymphoma.

Jin J, Okamoto R, Yoon SS, Shih LY, Zhu J, Liu T, Hong X, Pei L, Rooney B, van de Velde H, Huang H.

Onco Targets Ther. 2018 Jul 6;11:3869-3882. doi: 10.2147/OTT.S150339. eCollection 2018.


Arecoline inhibits the growth of 3T3-L1 preadipocytes via AMP-activated protein kinase and reactive oxygen species pathways.

Tian ZH, Weng JT, Shih LJ, Siao AC, Chan TY, Tsuei YW, Kuo YC, Wang TS, Kao YH.

PLoS One. 2018 Jul 16;13(7):e0200508. doi: 10.1371/journal.pone.0200508. eCollection 2018.


Extranodal NK/T-cell lymphoma, nasal type: Clinical features, outcome, and prognostic factors in 101 cases.

Su YJ, Wang PN, Chang H, Shih LY, Lin TL, Kuo MC, Chuang WY, Wu JH, Tang TC, Hung YS, Dunn P, Kao HW.

Eur J Haematol. 2018 Sep;101(3):379-388. doi: 10.1111/ejh.13126. Epub 2018 Jul 27.


The clinical impact of supraclavicular lymph node metastasis in patients with locally advanced esophageal squamous cell carcinoma receiving curative concurrent chemoradiotherapy.

Chen YH, Lu HI, Lo CM, Wang YM, Chou SY, Huang CH, Shih LH, Chen SW, Li SH.

PLoS One. 2018 Jun 11;13(6):e0198800. doi: 10.1371/journal.pone.0198800. eCollection 2018.


Association of Matrix Metalloproteinase-7 Genotypes to the Risk of Oral Cancer in Taiwan.

Shih LC, Li CH, Sun KT, Chen LY, Hsu CL, Hung YW, Wu CN, Hsia TC, Shen TC, Chang WS, Shih TC, Tsai CW, Bau DT.

Anticancer Res. 2018 Apr;38(4):2087-2092.


Qualitative CT Criterion for Subsolid Nodule Subclassification: Improving Interobserver Agreement and Pathologic Correlation in the Adenocarcinoma Spectrum.

Chen PA, Huang EP, Shih LY, Tang EK, Chien CC, Wu MT, Wu FZ.

Acad Radiol. 2018 Nov;25(11):1439-1445. doi: 10.1016/j.acra.2018.01.011. Epub 2018 Mar 9.


Surgical treatments for essential tremor.

Elble RJ, Shih L, Cozzens JW.

Expert Rev Neurother. 2018 Apr;18(4):303-321. doi: 10.1080/14737175.2018.1445526. Epub 2018 Mar 1. Review.


Computed tomography analysis of frontal cell prevalence according to the International Frontal Sinus Anatomy Classification.

Choby G, Thamboo A, Won TB, Kim J, Shih LC, Hwang PH.

Int Forum Allergy Rhinol. 2018 Jul;8(7):825-830. doi: 10.1002/alr.22105. Epub 2018 Feb 19.


Postoperative Changes in the Systemic Inflammatory Milieu in Older Surgical Patients.

Shih L, Guler N, Syed D, Hopkinson W, McComas KN, Walborn A, Hoppensteadt D, Fareed J, Rondina MT.

Clin Appl Thromb Hemost. 2018 May;24(4):583-588. doi: 10.1177/1076029617747412. Epub 2017 Dec 19.


Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

Walsh RR, Krismer F, Galpern WR, Wenning GK, Low PA, Halliday G, Koroshetz WJ, Holton J, Quinn NP, Rascol O, Shaw LM, Eidelberg D, Bower P, Cummings JL, Abler V, Biedenharn J, Bitan G, Brooks DJ, Brundin P, Fernandez H, Fortier P, Freeman R, Gasser T, Hewitt A, Höglinger GU, Huentelman MJ, Jensen PH, Jeromin A, Kang UJ, Kaufmann H, Kellerman L, Khurana V, Klockgether T, Kim WS, Langer C, LeWitt P, Masliah E, Meissner W, Melki R, Ostrowitzki S, Piantadosi S, Poewe W, Robertson D, Roemer C, Schenk D, Schlossmacher M, Schmahmann JD, Seppi K, Shih L, Siderowf A, Stebbins GT, Stefanova N, Tsuji S, Sutton S, Zhang J.

Neurology. 2018 Jan 9;90(2):74-82. doi: 10.1212/WNL.0000000000004798. Epub 2017 Dec 13. Review.


The prognostic significance of celiac lymph node metastasis in patients with locally advanced esophageal squamous cell carcinoma receiving curative concurrent chemoradiotherapy.

Chen YH, Lu HI, Wang YM, Lo CM, Chou SY, Huang CH, Shih LH, Chen SW, Li SH.

Oncotarget. 2017 Oct 16;8(56):96190-96202. doi: 10.18632/oncotarget.21878. eCollection 2017 Nov 10.


The clinical and prognostic relevance of driver mutations in 203 Taiwanese patients with primary myelofibrosis.

Kuo MC, Lin TH, Sun CF, Lin TL, Wu JH, Wang PN, Huang YJ, Chang H, Huang TY, Shih LY.

J Clin Pathol. 2018 Jun;71(6):514-521. doi: 10.1136/jclinpath-2017-204829. Epub 2017 Dec 4.


Equivalence in outcomes between Draf 2B vs Draf 3 frontal sinusotomy for refractory chronic frontal rhinosinusitis.

Patel VS, Choby G, Shih LC, Patel ZM, Nayak JV, Hwang PH.

Int Forum Allergy Rhinol. 2018 Jan;8(1):25-31. doi: 10.1002/alr.22032. Epub 2017 Nov 13.


The Association of Flap Endonuclease 1 Genotypes with the Susceptibility of Endometriosis.

Chou AK, Shen MY, Chen FY, Hsiao CL, Shih LC, Chang WS, Tsai CW, Ying TH, Wu MH, Huang CY, Bau DT.

Cancer Genomics Proteomics. 2017 Nov-Dec;14(6):455-460.


The effect of a hepatitis pay-for-performance program on outcomes of patients undergoing antiviral therapy.

Chen TT, Hsueh YA, Ko CH, Shih LN, Yang SS.

Eur J Public Health. 2017 Dec 1;27(6):955-960. doi: 10.1093/eurpub/ckx114.


Evolution of the endoscopic modified Lothrop procedure: A systematic review and meta-analysis.

Shih LC, Patel VS, Choby GW, Nakayama T, Hwang PH.

Laryngoscope. 2018 Feb;128(2):317-326. doi: 10.1002/lary.26794. Epub 2017 Sep 16. Review.


Validation of the 18-gene classifier as a prognostic biomarker of distant metastasis in breast cancer.

Cheng SH, Huang TT, Cheng YH, Tan TBK, Horng CF, Wang YA, Brian NS, Shih LS, Yu BL.

PLoS One. 2017 Sep 8;12(9):e0184372. doi: 10.1371/journal.pone.0184372. eCollection 2017.


Mutational status of NRAS, KRAS, and PTPN11 genes is associated with genetic/cytogenetic features in children with B-precursor acute lymphoblastic leukemia.

Liang DC, Chen SH, Liu HC, Yang CP, Yeh TC, Jaing TH, Hung IJ, Hou JY, Lin TH, Lin CH, Shih LY.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26786. Epub 2017 Aug 29.


National randomized controlled trial of virtual house calls for Parkinson disease.

Beck CA, Beran DB, Biglan KM, Boyd CM, Dorsey ER, Schmidt PN, Simone R, Willis AW, Galifianakis NB, Katz M, Tanner CM, Dodenhoff K, Aldred J, Carter J, Fraser A, Jimenez-Shahed J, Hunter C, Spindler M, Reichwein S, Mari Z, Dunlop B, Morgan JC, McLane D, Hickey P, Gauger L, Richard IH, Mejia NI, Bwala G, Nance M, Shih LC, Singer C, Vargas-Parra S, Zadikoff C, Okon N, Feigin A, Ayan J, Vaughan C, Pahwa R, Dhall R, Hassan A, DeMello S, Riggare SS, Wicks P, Achey MA, Elson MJ, Goldenthal S, Keenan HT, Korn R, Schwarz H, Sharma S, Stevenson EA, Zhu W; Connect.Parkinson Investigators.

Neurology. 2017 Sep 12;89(11):1152-1161. doi: 10.1212/WNL.0000000000004357. Epub 2017 Aug 16.


Nilotinib dose-optimization in newly diagnosed chronic myeloid leukaemia in chronic phase: final results from ENESTxtnd.

Hughes TP, Munhoz E, Aurelio Salvino M, Ong TC, Elhaddad A, Shortt J, Quach H, Pavlovsky C, Louw VJ, Shih LY, Turkina AG, Meillon L, Jin Y, Acharya S, Dalal D, Lipton JH.

Br J Haematol. 2017 Oct;179(2):219-228. doi: 10.1111/bjh.14829. Epub 2017 Jul 12.


The Contribution of Matrix Metalloproteinase-8 Promoter Polymorphism to Oral Cancer Susceptibility.

Hung YW, Tsai CW, Wu CN, Shih LC, Chen YY, Liu YF, Hung HS, Shen MY, Chang WS, Bau DT.

In Vivo. 2017 Jul-Aug;31(4):585-590.


Proteome profiling reveals novel biomarkers to identify complicated parapneumonic effusions.

Wu KA, Wu CC, Chen CD, Chu CM, Shih LJ, Liu YC, Wang CL, Lin HH, Yang CY.

Sci Rep. 2017 Jun 22;7(1):4026. doi: 10.1038/s41598-017-04189-4.


Differential Interaction of Myoglobin with Select Fatty Acids of Carbon Chain Lengths C8 to C16.

Jue T, Shih L, Chung Y.

Lipids. 2017 Aug;52(8):711-727. doi: 10.1007/s11745-017-4272-z. Epub 2017 Jun 21.


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