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Protective Association Between Calcium Channel Blocker Use and Breast Cancer Recurrence in Postsurgical Women: A Population-Based Case-Control Study in Taiwan.

Shih JH, Kao LT, Chung CH, Liao GS, Fann LY, Chien WC, Li IH.

J Clin Pharmacol. 2020 Feb 5. doi: 10.1002/jcph.1579. [Epub ahead of print]


Association between major depressive disorder and subsequent tinnitus: A population-based study.

Kao LT, Shih JH, Yeh CB, Wang CH, Chen HC, Chien WC, Li IH.

J Affect Disord. 2020 Feb 15;263:367-372. doi: 10.1016/j.jad.2019.11.141. Epub 2019 Nov 30.


Comparison of the marginal hazard model and the sub-distribution hazard model for competing risks under an assumed copula.

Emura T, Shih JH, Ha ID, Wilke RA.

Stat Methods Med Res. 2019 Dec 22:962280219892295. doi: 10.1177/0962280219892295. [Epub ahead of print] No abstract available.


Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malignancy in lung adenocarcinoma.

Shih JH, Chen HY, Lin SC, Yeh YC, Shen R, Lang YD, Wu DC, Chen CY, Chen RH, Chou TY, Jou YS.

Nucleic Acids Res. 2020 Feb 20;48(3):1175-1191. doi: 10.1093/nar/gkz1149.


PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression.

Lang YD, Chen HY, Ho CM, Shih JH, Hsu EC, Shen R, Lee YC, Chen JW, Wu CY, Yeh HW, Chen RH, Jou YS.

Nat Commun. 2019 Dec 16;10(1):5716. doi: 10.1038/s41467-019-13665-6.


18F-DCFPyL PET/CT Imaging in Patients with Biochemical Recurrence Prostate Cancer after Primary Local Therapy.

Mena E, Lindenberg ML, Turkbey IB, Shih JH, Harmon SA, Lim I, Lin FI, Adler S, Eclarinal P, McKinney Y, Citrin D, Dahut W, Wood B, Krishnasamy V, Chang R, Levy E, Merino M, Pinto P, Eary JF, Choyke PL.

J Nucl Med. 2019 Nov 1. pii: jnumed.119.234799. doi: 10.2967/jnumed.119.234799. [Epub ahead of print]


Predicting and enhancing students' positive emotions: An empirical study from a Taiwanese sociocultural context.

Phan HP, Ngu BH, Lin RY, Wang HW, Shih JH, Shi SY.

Heliyon. 2019 Oct 5;5(10):e02550. doi: 10.1016/j.heliyon.2019.e02550. eCollection 2019 Oct.


Benzodiazepine receptor agonists and subsequent risk of psoriasis: A 5-year follow-up cohort study.

Li IH, Wang WM, Chien WC, Kao HH, Shih JH, Cheng YD, Pan KT, Kao LT.

J Am Acad Dermatol. 2019 Dec;81(6):1433-1435. doi: 10.1016/j.jaad.2019.06.005. Epub 2019 Jun 13. No abstract available.


The Roles Of Angiogenesis And Cancer Stem Cells In Sorafenib Drug Resistance In Hepatocellular Carcinoma.

Cheng CC, Chao WT, Liao CC, Shih JH, Lai YS, Hsu YH, Liu YH.

Onco Targets Ther. 2019 Oct 4;12:8217-8227. doi: 10.2147/OTT.S217468. eCollection 2019.


Ferumoxytol-Enhanced MR Lymphography for Detection of Metastatic Lymph Nodes in Genitourinary Malignancies: A Prospective Study.

Turkbey B, Czarniecki M, Shih JH, Harmon SA, Agarwal PK, Apolo AB, Citrin DE, Gulley JL, Harisinghani M, Madan RA, Metwalli AR, Paquette E, Pinto PA, Rais-Bahrami S, Rowe LS, Wood BJ, Jacobs PM, Lindenberg L, Dahut W, Choyke PL.

AJR Am J Roentgenol. 2020 Jan;214(1):105-113. doi: 10.2214/AJR.19.21264. Epub 2019 Oct 15.


Transplant Recipients Using Tacrolimus Had Higher Utilization of Healthcare Services Than Those Receiving Cyclosporine in Taiwan.

Lin YC, Tsai CS, Li IH, Tsai YT, Huang TY, Lee KF, Lin CS, Shih JH, Kao LT.

Front Pharmacol. 2019 Sep 19;10:1074. doi: 10.3389/fphar.2019.01074. eCollection 2019.


18F-Sodium fluoride PET/CT predicts overall survival in patients with advanced genitourinary malignancies treated with cabozantinib and nivolumab with or without ipilimumab.

Lim I, Lindenberg ML, Mena E, Verdini N, Shih JH, Mayfield C, Thompson R, Lin J, Vega A, Mallek M, Cadena J, Diaz C, Mortazavi A, Knopp M, Wright C, Stein M, Pal S, Choyke PL, Apolo AB.

Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):178-184. doi: 10.1007/s00259-019-04483-5. Epub 2019 Sep 14.


The effect of dextromethorphan use in Parkinson's disease: A 6-hydroxydopamine rat model and population-based study.

Liu CT, Kao LT, Shih JH, Chien WC, Chiu CH, Ma KH, Huang YS, Cheng CY, Shiue CY, Li IH.

Eur J Pharmacol. 2019 Nov 5;862:172639. doi: 10.1016/j.ejphar.2019.172639. Epub 2019 Sep 3.


Health Care Service Utilization After Various Vascular Access Selections.

Chang JT, Li IH, Shih JH, Chien WC, Pan KT, Wu ST, Tsai CS, Kao LT.

J Surg Res. 2019 Dec;244:166-173. doi: 10.1016/j.jss.2019.06.046. Epub 2019 Jul 9.


Evaluation of brain SERT with 4-[18F]-ADAM/micro-PET and hearing protective effects of dextromethorphan in hearing loss rat model.

Liu CT, Huang YS, Chen HC, Ma KH, Wang CH, Chiu CH, Shih JH, Kang HH, Shiue CY, Li IH.

Toxicol Appl Pharmacol. 2019 Sep 1;378:114604. doi: 10.1016/j.taap.2019.114604. Epub 2019 May 30.


IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion.

Conlon KC, Potter EL, Pittaluga S, Lee CR, Miljkovic MD, Fleisher TA, Dubois S, Bryant BR, Petrus M, Perera LP, Hsu J, Figg WD, Peer CJ, Shih JH, Yovandich JL, Creekmore SP, Roederer M, Waldmann TA.

Clin Cancer Res. 2019 Aug 15;25(16):4945-4954. doi: 10.1158/1078-0432.CCR-18-3468. Epub 2019 May 29.


Achieving optimal best practice: An inquiry into its nature and characteristics.

Phan HP, Ngu BH, Wang HW, Shih JH, Shi SY, Lin RY.

PLoS One. 2019 Apr 25;14(4):e0215732. doi: 10.1371/journal.pone.0215732. eCollection 2019.


Inverse Association of Fibrates and Liver Cancer: A Population-Based Case-Control Study in Taiwan.

Li IH, Shih JH, Tsai CS, Chien WC, Kao HH, Pan KT, Cheng YD, Kao LT.

J Clin Pharmacol. 2019 Sep;59(9):1170-1176. doi: 10.1002/jcph.1419. Epub 2019 Apr 9.


Regulation of Noise-Induced Loss of Serotonin Transporters with Resveratrol in a Rat Model Using 4-[18F]-ADAM/Small-Animal Positron Emission Tomography.

Li IH, Shih JH, Jhao YT, Chen HC, Chiu CH, Chen CF, Huang YS, Shiue CY, Ma KH.

Molecules. 2019 Apr 5;24(7). pii: E1344. doi: 10.3390/molecules24071344.


Interreader Variability of Prostate Imaging Reporting and Data System Version 2 in Detecting and Assessing Prostate Cancer Lesions at Prostate MRI.

Greer MD, Shih JH, Lay N, Barrett T, Bittencourt L, Borofsky S, Kabakus I, Law YM, Marko J, Shebel H, Merino MJ, Wood BJ, Pinto PA, Summers RM, Choyke PL, Turkbey B.

AJR Am J Roentgenol. 2019 Mar 27:1-8. doi: 10.2214/AJR.18.20536. [Epub ahead of print]


Autophagy inhibition plays a protective role against 3, 4-methylenedioxymethamphetamine (MDMA)-induced loss of serotonin transporters and depressive-like behaviors in rats.

Shih JH, Chiu CH, Ma KH, Huang YS, Shiue CY, Yeh TY, Kao LT, Lin YY, Li IH.

Pharmacol Res. 2019 Apr;142:283-293. doi: 10.1016/j.phrs.2019.02.026. Epub 2019 Feb 28.


A comparison of prostate cancer bone metastases on 18F-Sodium Fluoride and Prostate Specific Membrane Antigen (18F-PSMA) PET/CT: Discordant uptake in the same lesion.

Harmon SA, Mena E, Shih JH, Adler S, McKinney Y, Bergvall E, Mehralivand S, Sowalsky AG, Couvillon A, Madan RA, Gulley JL, Eary J, Mease RC, Pomper MG, Dahut WL, Turkbey B, Lindenberg L, Choyke PL.

Oncotarget. 2018 Dec 28;9(102):37676-37688. doi: 10.18632/oncotarget.26481. eCollection 2018 Dec 28.


When to Biopsy the Seminal Vesicles: A Validated Multiparametric Magnetic Resonance Imaging and Target Driven Model to Detect Seminal Vesicle Invasion in Prostate Cancer.

Gold SA, Shih JH, Rais-Bahrami S, Bloom JB, Vourganti S, Singla N, Baroni RH, Coker MA, Fialkoff J, Noschang J, Roehrborn CG, Turkbey B, Pinto PA; Collaborators.

J Urol. 2019 Jan 23. doi: 10.1097/JU.0000000000000112. [Epub ahead of print]


A Grading System for the Assessment of Risk of Extraprostatic Extension of Prostate Cancer at Multiparametric MRI.

Mehralivand S, Shih JH, Harmon S, Smith C, Bloom J, Czarniecki M, Gold S, Hale G, Rayn K, Merino MJ, Wood BJ, Pinto PA, Choyke PL, Turkbey B.

Radiology. 2019 Mar;290(3):709-719. doi: 10.1148/radiol.2018181278. Epub 2019 Jan 22.


Intra- and interreader reproducibility of PI-RADSv2: A multireader study.

Smith CP, Harmon SA, Barrett T, Bittencourt LK, Law YM, Shebel H, An JY, Czarniecki M, Mehralivand S, Coskun M, Wood BJ, Pinto PA, Shih JH, Choyke PL, Turkbey B.

J Magn Reson Imaging. 2019 Jun;49(6):1694-1703. doi: 10.1002/jmri.26555. Epub 2018 Dec 21.


Androgen Deprivation Therapy Use Increases the Risk of Heart Failure in Patients With Prostate Cancer: A Population-Based Cohort Study.

Kao HH, Kao LT, Li IH, Pan KT, Shih JH, Chou YC, Wu ST.

J Clin Pharmacol. 2019 Mar;59(3):335-343. doi: 10.1002/jcph.1332. Epub 2018 Nov 7.


Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation.

Gaur S, Lay N, Harmon SA, Doddakashi S, Mehralivand S, Argun B, Barrett T, Bednarova S, Girometti R, Karaarslan E, Kural AR, Oto A, Purysko AS, Antic T, Magi-Galluzzi C, Saglican Y, Sioletic S, Warren AY, Bittencourt L, Fütterer JJ, Gupta RT, Kabakus I, Law YM, Margolis DJ, Shebel H, Westphalen AC, Wood BJ, Pinto PA, Shih JH, Choyke PL, Summers RM, Turkbey B.

Oncotarget. 2018 Sep 18;9(73):33804-33817. doi: 10.18632/oncotarget.26100. eCollection 2018 Sep 18.


A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma.

Koehler JW, Miller AD, Miller CR, Porter B, Aldape K, Beck J, Brat D, Cornax I, Corps K, Frank C, Giannini C, Horbinski C, Huse JT, O'Sullivan MG, Rissi DR, Mark Simpson R, Woolard K, Shih JH, Mazcko C, Gilbert MR, LeBlanc AK.

J Neuropathol Exp Neurol. 2018 Nov 1;77(11):1039-1054. doi: 10.1093/jnen/nly085.


Pioglitazone use and Parkinson's disease: a retrospective cohort study in Taiwan.

Wu HF, Kao LT, Shih JH, Kao HH, Chou YC, Li IH, Kao S.

BMJ Open. 2018 Aug 29;8(8):e023302. doi: 10.1136/bmjopen-2018-023302.


Disease-specific health literacy, disease knowledge, and adherence behavior among patients with type 2 diabetes in Taiwan.

Yeh JZ, Wei CJ, Weng SF, Tsai CY, Shih JH, Shih CL, Chiu CH.

BMC Public Health. 2018 Aug 24;18(1):1062. doi: 10.1186/s12889-018-5972-x.


Association between peripheral manganese levels and attention-deficit/hyperactivity disorder: a preliminary meta-analysis.

Shih JH, Zeng BY, Lin PY, Chen TY, Chen YW, Wu CK, Tseng PT, Wu MK.

Neuropsychiatr Dis Treat. 2018 Jul 18;14:1831-1842. doi: 10.2147/NDT.S165378. eCollection 2018. Review.


A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells.

Przepiorski A, Sander V, Tran T, Hollywood JA, Sorrenson B, Shih JH, Wolvetang EJ, McMahon AP, Holm TM, Davidson AJ.

Stem Cell Reports. 2018 Aug 14;11(2):470-484. doi: 10.1016/j.stemcr.2018.06.018. Epub 2018 Jul 19.


Understanding levels of best practice: An empirical validation.

Phan HP, Ngu BH, Wang HW, Shih JH, Shi SY, Lin RY.

PLoS One. 2018 Jun 14;13(6):e0198888. doi: 10.1371/journal.pone.0198888. eCollection 2018.


Causal estimands and confidence intervals associated with Wilcoxon-Mann-Whitney tests in randomized experiments.

Fay MP, Brittain EH, Shih JH, Follmann DA, Gabriel EE.

Stat Med. 2018 Sep 10;37(20):2923-2937. doi: 10.1002/sim.7799. Epub 2018 May 17.


Differentiating pseudoprogression from true progression: analysis of radiographic, biologic, and clinical clues in GBM.

Rowe LS, Butman JA, Mackey M, Shih JH, Cooley-Zgela T, Ning H, Gilbert MR, Smart DK, Camphausen K, Krauze AV.

J Neurooncol. 2018 Aug;139(1):145-152. doi: 10.1007/s11060-018-2855-z. Epub 2018 May 16.


Evaluating the size criterion for PI-RADSv2 category 5 upgrade: is 15 mm the best threshold?

An JY, Harmon SA, Mehralivand S, Czarniecki M, Smith CP, Peretti JA, Wood BJ, Pinto PA, Choyke PL, Shih JH, Turkbey B.

Abdom Radiol (NY). 2018 Dec;43(12):3436-3444. doi: 10.1007/s00261-018-1631-z.


Can Apparent Diffusion Coefficient Values Assist PI-RADS Version 2 DWI Scoring? A Correlation Study Using the PI-RADSv2 and International Society of Urological Pathology Systems.

Gaur S, Harmon S, Rosenblum L, Greer MD, Mehralivand S, Coskun M, Merino MJ, Wood BJ, Shih JH, Pinto PA, Choyke PL, Turkbey B.

AJR Am J Roentgenol. 2018 Jul;211(1):W33-W41. doi: 10.2214/AJR.17.18702. Epub 2018 May 7.


A Multireader Exploratory Evaluation of Individual Pulse Sequence Cancer Detection on Prostate Multiparametric Magnetic Resonance Imaging (MRI).

Gaur S, Harmon S, Gupta RT, Margolis DJ, Lay N, Mehralivand S, Merino MJ, Wood BJ, Pinto PA, Shih JH, Choyke PL, Turkbey B.

Acad Radiol. 2019 Jan;26(1):5-14. doi: 10.1016/j.acra.2018.03.024. Epub 2018 Apr 25.


Computer-aided diagnosis prior to conventional interpretation of prostate mpMRI: an international multi-reader study.

Greer MD, Lay N, Shih JH, Barrett T, Bittencourt LK, Borofsky S, Kabakus I, Law YM, Marko J, Shebel H, Mertan FV, Merino MJ, Wood BJ, Pinto PA, Summers RM, Choyke PL, Turkbey B.

Eur Radiol. 2018 Oct;28(10):4407-4417. doi: 10.1007/s00330-018-5374-6. Epub 2018 Apr 12.


Prospective comparison of PI-RADS version 2 and qualitative in-house categorization system in detection of prostate cancer.

Gaur S, Harmon S, Mehralivand S, Bednarova S, Calio BP, Sugano D, Sidana A, Merino MJ, Pinto PA, Wood BJ, Shih JH, Choyke PL, Turkbey B.

J Magn Reson Imaging. 2018 Nov;48(5):1326-1335. doi: 10.1002/jmri.26025. Epub 2018 Mar 31.


A Prospective Comparison of 18F-Sodium Fluoride PET/CT and PSMA-Targeted 18F-DCFBC PET/CT in Metastatic Prostate Cancer.

Harmon SA, Bergvall E, Mena E, Shih JH, Adler S, McKinney Y, Mehralivand S, Citrin DE, Couvillon A, Madan RA, Gulley JL, Mease RC, Jacobs PM, Pomper MG, Turkbey B, Choyke PL, Lindenberg ML.

J Nucl Med. 2018 Nov;59(11):1665-1671. doi: 10.2967/jnumed.117.207373. Epub 2018 Mar 30.


PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis.

Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, Yang RB, Jou YS.

Nat Cell Biol. 2018 Apr;20(4):479-491. doi: 10.1038/s41556-018-0062-y. Epub 2018 Mar 28.


The Problems with the Kappa Statistic as a Metric of Interobserver Agreement on Lesion Detection Using a Third-reader Approach When Locations Are Not Prespecified.

Shih JH, Greer MD, Turkbey B.

Acad Radiol. 2018 Oct;25(10):1325-1332. doi: 10.1016/j.acra.2018.01.030. Epub 2018 Mar 16.


A Magnetic Resonance Imaging-Based Prediction Model for Prostate Biopsy Risk Stratification.

Mehralivand S, Shih JH, Rais-Bahrami S, Oto A, Bednarova S, Nix JW, Thomas JV, Gordetsky JB, Gaur S, Harmon SA, Siddiqui MM, Merino MJ, Parnes HL, Wood BJ, Pinto PA, Choyke PL, Turkbey B.

JAMA Oncol. 2018 May 1;4(5):678-685. doi: 10.1001/jamaoncol.2017.5667.


All over the map: An interobserver agreement study of tumor location based on the PI-RADSv2 sector map.

Greer MD, Shih JH, Barrett T, Bednarova S, Kabakus I, Law YM, Shebel H, Merino MJ, Wood BJ, Pinto PA, Choyke PL, Turkbey B.

J Magn Reson Imaging. 2018 Aug;48(2):482-490. doi: 10.1002/jmri.25948. Epub 2018 Jan 17.


Multiparametric MRI for the detection of local recurrence of prostate cancer in the setting of biochemical recurrence after low dose rate brachytherapy.

Valle LF, Greer MD, Shih JH, Barrett T, Law YM, Rosenkrantz AB, Shebel H, Muthigi A, Su D, Merino MJ, Wood BJ, Pinto PA, Krauze AV, Kaushal A, Choyke PL, Türkbey B, Citrin DE.

Diagn Interv Radiol. 2018 Jan-Feb;24(1):46-53. doi: 10.5152/dir.2018.17285.


Interpersonal predictors of stress generation: Is there a super factor?

Shih JH, Barstead MG, Dianno N.

Br J Psychol. 2018 Aug;109(3):466-486. doi: 10.1111/bjop.12278. Epub 2017 Dec 10.


Clinical impact of PSMA-based 18F-DCFBC PET/CT imaging in patients with biochemically recurrent prostate cancer after primary local therapy.

Mena E, Lindenberg ML, Shih JH, Adler S, Harmon S, Bergvall E, Citrin D, Dahut W, Ton AT, McKinney Y, Weaver J, Eclarinal P, Forest A, Afari G, Bhattacharyya S, Mease RC, Merino MJ, Pinto P, Wood BJ, Jacobs P, Pomper MG, Choyke PL, Turkbey B.

Eur J Nucl Med Mol Imaging. 2018 Jan;45(1):4-11. doi: 10.1007/s00259-017-3818-x. Epub 2017 Sep 11.


Validation of the Dominant Sequence Paradigm and Role of Dynamic Contrast-enhanced Imaging in PI-RADS Version 2.

Greer MD, Shih JH, Lay N, Barrett T, Kayat Bittencourt L, Borofsky S, Kabakus IM, Law YM, Marko J, Shebel H, Mertan FV, Merino MJ, Wood BJ, Pinto PA, Summers RM, Choyke PL, Turkbey B.

Radiology. 2017 Dec;285(3):859-869. doi: 10.1148/radiol.2017161316. Epub 2017 Jul 19.


Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling.

Huang YC, Tsai MS, Hsieh PC, Shih JH, Wang TS, Wang YC, Lin TH, Wang SH.

Toxicol Appl Pharmacol. 2017 Aug 15;329:128-139. doi: 10.1016/j.taap.2017.05.034. Epub 2017 May 27.


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