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Risk factors in metabolic syndrome predict the progression of diabetic nephropathy in patients with type 2 diabetes.

Chuang SM, Shih HM, Chien MN, Liu SC, Wang CH, Lee CC.

Diabetes Res Clin Pract. 2019 Jul;153:6-13. doi: 10.1016/j.diabres.2019.04.022. Epub 2019 May 4.


Corrigendum to "Intelligent system to predict intradialytic hypotension in chronic hemodialysis" [J Formos Med Assoc (2018) [888-893].

Lin CJ, Chen CY, Wu PC, Pan CF, Shih HM, Huang MY, Chou LH, Tang JS, Wu CJ.

J Formos Med Assoc. 2019 May;118(5):955-956. doi: 10.1016/j.jfma.2019.04.004. No abstract available.


Association of sudden in-hospital cardiac arrest with emergency department crowding.

Chang YH, Shih HM, Chen CY, Chen WK, Huang FW, Muo CH.

Resuscitation. 2019 May;138:106-109. doi: 10.1016/j.resuscitation.2019.03.001. Epub 2019 Mar 9.


Association between intensive periodontal treatment and spontaneous intracerebral hemorrhage-a nationwide, population-based cohort study.

Huang JL, Chen WK, Lin CL, Lai CY, Kao CH, Chiang HH, Yang TY, Shih HM.

Medicine (Baltimore). 2019 Mar;98(10):e14814. doi: 10.1097/MD.0000000000014814.


Social media communication shorten door-to-balloon time in patients with ST-elevation myocardial infarction.

Yu SH, Shih HM, Chang SS, Chen WK, Li CY.

Medicine (Baltimore). 2019 Mar;98(10):e14791. doi: 10.1097/MD.0000000000014791.


Derivation and Validation of the SWAP Score for Very Early Prediction of Neurologic Outcome in Patients With Out-of-Hospital Cardiac Arrest.

Shih HM, Chen YC, Chen CY, Huang FW, Chang SS, Yu SH, Wu SY, Chen WK.

Ann Emerg Med. 2019 Jun;73(6):578-588. doi: 10.1016/j.annemergmed.2019.01.017. Epub 2019 Feb 26.


Erythropoietin modulates macrophages but not post-ischemic acute kidney injury in mice.

Chou YH, Liao FL, Chen YT, Yeh PY, Liu CH, Shih HM, Chang FC, Chiang WC, Chu TS, Lin SL.

J Formos Med Assoc. 2019 Jan;118(1 Pt 3):494-503. doi: 10.1016/j.jfma.2018.10.015. Epub 2018 Nov 7.


Results of Fabry Disease Screening in Male Pre-End Stage Renal Disease Patients with Unknown Etiology Found Through the Platform of a Chronic Kidney Disease Education Program in a Northern Taiwan Medical Center.

Lin CJ, Chien YH, Lai TS, Shih HM, Chen YC, Pan CF, Chen HH, Hwu WL, Wu CJ.

Kidney Blood Press Res. 2018;43(5):1636-1645. doi: 10.1159/000494678. Epub 2018 Oct 31.


The use of extracorporeal membrane oxygenation in trauma patients: A national case-control study.

Chen CY, Hsu TY, Chen WK, Muo CH, Chen HC, Shih HM.

Medicine (Baltimore). 2018 Sep;97(36):e12223. doi: 10.1097/MD.0000000000012223.


Association between sleep disorders and subsequent chronic spontaneous urticaria development: A population-based cohort study.

He GY, Tsai TF, Lin CL, Shih HM, Hsu TY.

Medicine (Baltimore). 2018 Aug;97(34):e11992. doi: 10.1097/MD.0000000000011992.


Regulation of axon repulsion by MAX-1 SUMOylation and AP-3.

Chen SY, Ho CT, Liu WW, Lucanic M, Shih HM, Huang PH, Cheng HJ.

Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8236-E8245. doi: 10.1073/pnas.1804373115. Epub 2018 Aug 13.


The role of sentrin-specific protease 2 substrate recognition in TGF-β-induced tumorigenesis.

Chang CC, Huang YS, Lin YM, Lin CJ, Jeng JC, Liu SM, Ho TL, Chang RT, Changou CA, Ho CC, Shih HM.

Sci Rep. 2018 Jun 28;8(1):9786. doi: 10.1038/s41598-018-28103-8.


Intelligent system to predict intradialytic hypotension in chronic hemodialysis.

Lin CJ, Chen CY, Wu PC, Pan CF, Shih HM, Huang MY, Chou LH, Tang JS, Wu CJ.

J Formos Med Assoc. 2018 Oct;117(10):888-893. doi: 10.1016/j.jfma.2018.05.023. Epub 2018 Jun 22. Erratum in: J Formos Med Assoc. 2019 May;118(5):955-956.


SUMOylation of XRCC1 activated by poly (ADP-ribosyl)ation regulates DNA repair.

Hu LY, Chang CC, Huang YS, Chou WC, Lin YM, Ho CC, Chen WT, Shih HM, Hsiung CN, Wu PE, Shen CY.

Hum Mol Genet. 2018 Jul 1;27(13):2306-2317. doi: 10.1093/hmg/ddy135.


Physiology and pathophysiology of renal erythropoietin-producing cells.

Shih HM, Wu CJ, Lin SL.

J Formos Med Assoc. 2018 Nov;117(11):955-963. doi: 10.1016/j.jfma.2018.03.017. Epub 2018 Apr 11. Review.


Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression.

Lin CY, Yang ST, Shen SC, Hsieh YC, Hsu FT, Chen CY, Chiang YH, Chuang JY, Chen KY, Hsu TI, Leong WC, Su YK, Lo WL, Yeh YS, Patria YN, Shih HM, Chang CC, Chou SY.

Mol Oncol. 2018 May;12(5):756-771. doi: 10.1002/1878-0261.12196. Epub 2018 Apr 17.


Author Correction: Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction.

Naik MT, Kang M, Ho CC, Liao PH, Hsieh YL, Naik NM, Wang SH, Chang I, Shih HM, Huang TH.

Sci Rep. 2018 Mar 19;8(1):5022. doi: 10.1038/s41598-018-23157-0.


Role of melatonin receptor 1A and pituitary homeobox-1 coexpression in protecting tubular epithelial cells in membranous nephropathy.

Huang YS, Lu KC, Chao TK, Chen JS, Chen A, Guo CY, Hsieh HY, Shih HM, Sytwu HK, Wu CC.

J Pineal Res. 2018 Aug;65(1):e12482. doi: 10.1111/jpi.12482. Epub 2018 Mar 25.


Molecular mechanism of K65 acetylation-induced attenuation of Ubc9 and the NDSM interaction.

Naik MT, Kang M, Ho CC, Liao PH, Hsieh YL, Naik NM, Wang SH, Chang I, Shih HM, Huang TH.

Sci Rep. 2017 Dec 12;7(1):17391. doi: 10.1038/s41598-017-17465-0. Erratum in: Sci Rep. 2018 Mar 19;8(1):5022.


Sex hormone-binding globulin (SHBG) is a potential early diagnostic biomarker for gastric cancer.

Cheng CW, Chang CC, Patria YN, Chang RT, Liu YR, Li FA, Shih HM, Lin CY.

Cancer Med. 2018 Jan;7(1):64-74. doi: 10.1002/cam4.1254. Epub 2017 Nov 17.


Effect of alcohol intoxication on the risk of venous thromboembolism: A nationwide retrospective cohort study.

Shen CJ, Kao CH, Hsu TY, Chen CY, Lin CL, Shih HM.

Medicine (Baltimore). 2017 Oct;96(42):e8041. doi: 10.1097/MD.0000000000008041.


Association of EV71 3C polymorphisms with clinical severity.

Ma HY, Lu CY, Tsao KC, Shih HM, Cheng AL, Huang LM, Chang LY.

J Microbiol Immunol Infect. 2018 Oct;51(5):608-613. doi: 10.1016/j.jmii.2016.12.006. Epub 2017 Jun 28.


Effect of Alcoholic Intoxication on the Risk of Inflammatory Bowel Disease: A Nationwide Retrospective Cohort Study.

Hsu TY, Shih HM, Wang YC, Lin LC, He GY, Chen CY, Kao CH, Chen CH, Chen WK, Yang TY.

PLoS One. 2016 Nov 1;11(11):e0165411. doi: 10.1371/journal.pone.0165411. eCollection 2016.


Analysis of Patients with Helicobacter pylori Infection and the Subsequent Risk of Developing Osteoporosis after Eradication Therapy: A Nationwide Population-Based Cohort Study.

Shih HM, Hsu TY, Chen CY, Lin CL, Kao CH, Chen CH, Yang TY, Chen WK.

PLoS One. 2016 Sep 14;11(9):e0162645. doi: 10.1371/journal.pone.0162645. eCollection 2016.


Eosinophilic Gastroenteritis : Brief Review.

Shih HM, Bair MJ, Chen HL, Lin IT.

Acta Gastroenterol Belg. 2016 Apr-Jun;79(2):239-44. Review.


Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression.

Huang YS, Chang CC, Lee SS, Jou YS, Shih HM.

Oncotarget. 2016 Jul 12;7(28):43256-43266. doi: 10.18632/oncotarget.9673.


RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner.

Kuo CY, Li X, Stark JM, Shih HM, Ann DK.

Cell Cycle. 2016;15(6):787-98. doi: 10.1080/15384101.2016.1138184.


Preliminary Prospective Study to Assess the Effect of Early Blood Urea Nitrogen/Creatinine Ratio-Based Hydration Therapy on Poststroke Infection Rate and Length of Stay in Acute Ischemic Stroke.

Lin WC, Shih HM, Lin LC.

J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2720-7. doi: 10.1016/j.jstrokecerebrovasdis.2015.08.002. Epub 2015 Aug 31.


HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.

Ho YK, Zhi H, Bowlin T, Dorjbal B, Philip S, Zahoor MA, Shih HM, Semmes OJ, Schaefer B, Glover JN, Giam CZ.

PLoS Pathog. 2015 Aug 18;11(8):e1005102. doi: 10.1371/journal.ppat.1005102. eCollection 2015 Aug.


Daxx and TCF4 interaction links to oral squamous cell carcinoma growth by promoting cell cycle progression via induction of cyclin D1 expression.

Lin GJ, Huang YS, Lin CK, Huang SH, Shih HM, Sytwu HK, Chen YW.

Clin Oral Investig. 2016 Apr;20(3):533-40. doi: 10.1007/s00784-015-1536-y. Epub 2015 Jul 24.


Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection.

Chiang YP, Sheng WH, Shao PL, Chi YH, Chen YM, Huang SW, Shih HM, Chang LY, Lu CY, Chang SC, Hung CC, Huang LM.

EBioMedicine. 2014 Oct 7;1(2-3):126-32. doi: 10.1016/j.ebiom.2014.10.002. eCollection 2014 Dec.


The author responds:.

Shih HM.

Am J Emerg Med. 2015 Feb;33(2):302. No abstract available.


Is red blood cell distribution width enough to predict prognosis of necrotizing fasciitis: author's reply.

Shih HM.

Am J Emerg Med. 2015 Mar;33(3):468. doi: 10.1016/j.ajem.2014.12.004. Epub 2014 Dec 15. No abstract available.


The RING domain of human promyelocytic leukemia protein (PML).

Huang SY, Chang CF, Fang PJ, Naik MT, Güntert P, Shih HM, Huang TH.

J Biomol NMR. 2015 Feb;61(2):173-80. doi: 10.1007/s10858-015-9901-3. Epub 2015 Jan 28. No abstract available.


PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2.

Kuo HY, Huang YS, Tseng CH, Chen YC, Chang YW, Shih HM, Wu CW.

Cell Cycle. 2014;13(19):3132-42. doi: 10.4161/15384101.2014.949212.


Can red cell distribution width predict mortality rate in patients with necrotizing fasciitis? The Author's Reply.

Shih HM.

Am J Emerg Med. 2014 Dec;32(12):1538. doi: 10.1016/j.ajem.2014.10.001. Epub 2014 Oct 7. No abstract available.


The B-box 1 dimer of human promyelocytic leukemia protein.

Huang SY, Naik MT, Chang CF, Fang PJ, Wang YH, Shih HM, Huang TH.

J Biomol NMR. 2014 Dec;60(4):275-81. doi: 10.1007/s10858-014-9869-4. Epub 2014 Oct 30. No abstract available.


Hypertensive patients using thiazide diuretics as primary stroke prevention make better functional outcome after ischemic stroke.

Shih HM, Lin WC, Wang CH, Lin LC.

J Stroke Cerebrovasc Dis. 2014 Oct;23(9):2414-8. doi: 10.1016/j.jstrokecerebrovasdis.2014.05.021. Epub 2014 Aug 31.


Red cell distribution width is an independent predictor of mortality in necrotizing fasciitis.

Weng CL, Wang CH, Chen IC, Hsiao KY, Chang KP, Wu SY, Shih HM.

Am J Emerg Med. 2014 Oct;32(10):1259-62. doi: 10.1016/j.ajem.2014.08.001. Epub 2014 Aug 7.


Urinary Xist is a potential biomarker for membranous nephropathy.

Huang YS, Hsieh HY, Shih HM, Sytwu HK, Wu CC.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):415-21. doi: 10.1016/j.bbrc.2014.08.077. Epub 2014 Aug 23.


An arginine-rich motif of ring finger protein 4 (RNF4) oversees the recruitment and degradation of the phosphorylated and SUMOylated Krüppel-associated box domain-associated protein 1 (KAP1)/TRIM28 protein during genotoxic stress.

Kuo CY, Li X, Kong XQ, Luo C, Chang CC, Chung Y, Shih HM, Li KK, Ann DK.

J Biol Chem. 2014 Jul 25;289(30):20757-72. doi: 10.1074/jbc.M114.555672. Epub 2014 Jun 6.


Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.

Kung CC, Naik MT, Wang SH, Shih HM, Chang CC, Lin LY, Chen CL, Ma C, Chang CF, Huang TH.

Biochem J. 2014 Aug 15;462(1):53-65. doi: 10.1042/BJ20140521.


Aortoiliac occlusive disease presenting as sudden onset paraplegia.

Lai CH, Wang CH, Wu SY, Shih HM.

Ann Vasc Surg. 2014 Jul;28(5):1321.e5-7. doi: 10.1016/j.avsg.2013.12.013. Epub 2014 Feb 5.


HIC1 interacts with and modulates the activity of STAT3.

Lin YM, Wang CM, Jeng JC, Leprince D, Shih HM.

Cell Cycle. 2013 Jul 15;12(14):2266-76. doi: 10.4161/cc.25365.


SENP1 deSUMOylates and regulates Pin1 protein activity and cellular function.

Chen CH, Chang CC, Lee TH, Luo M, Huang P, Liao PH, Wei S, Li FA, Chen RH, Zhou XZ, Shih HM, Lu KP.

Cancer Res. 2013 Jul 1;73(13):3951-62. doi: 10.1158/0008-5472.CAN-12-4360. Epub 2013 Apr 30. Erratum in: Cancer Res. 2017 Apr 15;77(8):2173.


HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response.

Lee YH, Kuo CY, Stark JM, Shih HM, Ann DK.

Nucleic Acids Res. 2013 Jun;41(11):5784-98. doi: 10.1093/nar/gkt231. Epub 2013 Apr 15.


The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer.

Kuo HY, Chen YC, Chang HY, Jeng JC, Lin EH, Pan CM, Chang YW, Wang ML, Chou YT, Shih HM, Wu CW.

Carcinogenesis. 2013 Aug;34(8):1708-16. doi: 10.1093/carcin/bgt109. Epub 2013 Apr 4.


Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human.

Lo YH, Huang YW, Wu YH, Tsai CS, Lin YC, Mo ST, Kuo WC, Chuang YT, Jiang ST, Shih HM, Lai MZ.

Blood. 2013 Apr 18;121(16):3185-94. doi: 10.1182/blood-2012-05-432104. Epub 2013 Feb 21.


Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response.

Hsieh YL, Kuo HY, Chang CC, Naik MT, Liao PH, Ho CC, Huang TC, Jeng JC, Hsu PH, Tsai MD, Huang TH, Shih HM.

EMBO J. 2013 Mar 20;32(6):791-804. doi: 10.1038/emboj.2013.5. Epub 2013 Feb 8.


The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.

Yang WC, Shih HM.

Oncogene. 2013 Oct 24;32(43):5167-75. doi: 10.1038/onc.2012.537. Epub 2012 Dec 3.


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