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Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors (GISTs) and Acute Myeloid Leukemia (AML).

Lin WH, Wu S, Yeh TK, Chen CT, Song JS, Shiao HY, Kuo CC, Hsu T, Lu CT, Wang PC, Wu TS, Peng YH, Lin HY, Chen CP, Weng YL, Kung FC, Wu MH, Su YC, Huang KW, Chou LH, Hsueh CC, Yen KJ, Kuo PC, Huang CL, Chen LT, Shih C, Tsai HJ, Jiaang WT.

J Med Chem. 2019 Nov 13. doi: 10.1021/acs.jmedchem.9b01229. [Epub ahead of print]


Effect of the Integrated Prospective Payment Program on Family Members' Knowledge and Acceptance of Hospice Care of Patients on Prolonged Mechanical Ventilation.

Liu CJ, Kung PT, Chu CC, Chou WY, Shih CM, Tsai WC.

Respir Care. 2019 Nov 12. pii: respcare.06934. doi: 10.4187/respcare.06934. [Epub ahead of print]


Lactobacillus acidophilus-Fermented Germinated Brown Rice Suppresses Preneoplastic Lesions of the Colon in Rats.

Li SC, Lin HP, Chang JS, Shih CK.

Nutrients. 2019 Nov 9;11(11). pii: E2718. doi: 10.3390/nu11112718.


New silky lacewings from mid-Cretaceous Burmese amber (Insecta: Neuroptera: Psychopsidae).

Bai H, Chang YU, Shih C, Ren D, Wang Y.

Zootaxa. 2019 Aug 27;4661(1):zootaxa.4661.1.10. doi: 10.11646/zootaxa.4661.1.10.


Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model.

Liou AT, Liao CC, Chou SF, Chang YS, Chang CS, Shih C.

J Biomed Sci. 2019 Nov 11;26(1):93. doi: 10.1186/s12929-019-0585-y.


Oral administration of transgenic biosafe microorganism containing antimicrobial peptide enhances the survival of tilapia fry infected bacterial pathogen.

Lee BC, Hung CW, Lin CY, Shih CH, Tsai HJ.

Fish Shellfish Immunol. 2019 Nov 1. pii: S1050-4648(19)31020-4. doi: 10.1016/j.fsi.2019.10.052. [Epub ahead of print]


Fibroblast Growth Factor Receptor Inhibitors Reduce Adipogenesis of Orbital Fibroblasts and Enhance Myofibroblastic Differentiation in Graves' Orbitopathy.

Shih SR, Shih CW, Wei YH, Lu TX, Chou CH, Yen EY, Chang YC, Lin CC, Chi YC, Yang WS, Liao SL, Tsai FC.

Ocul Immunol Inflamm. 2019 Oct 28:1-10. doi: 10.1080/09273948.2019.1672196. [Epub ahead of print]


Role of nuclear factor-kappa B in feline injection site sarcoma.

Hsueh CS, Wu CH, Shih CH, Yeh JL, Jeng CR, Pang VF, Chiou HY, Chang HW.

BMC Vet Res. 2019 Oct 25;15(1):365. doi: 10.1186/s12917-019-2100-9.


Evaluation of white sweet potato tube-feeding formula in elderly diabetic patients: a randomized controlled trial.

Chen CM, Shih CK, Su YJ, Cheang KU, Lo SF, Li SC.

Nutr Metab (Lond). 2019 Oct 16;16:70. doi: 10.1186/s12986-019-0398-8. eCollection 2019.


Anti-inflammatory compound shows therapeutic safety and efficacy against flavivirus infection.

Chuang FK, Huang SM, Liao CL, Lee AR, Lien SP, Chiu YL, Chang TH, Tsai PL, Lin RJ, Shih CC, Tsai YJ, Lin GJ, Yen LC.

Antimicrob Agents Chemother. 2019 Oct 21. pii: AAC.00941-19. doi: 10.1128/AAC.00941-19. [Epub ahead of print]


Medication-Taking Habit and Outcome of Glucosamine Sulfate for Osteoarthritis Patients Influenced by National Health Insurance Regulations in Taiwan.

Hsu CH, Hsu NC, Shih CL, Huang HT, Chen CH, Chou PH.

J Clin Med. 2019 Oct 19;8(10). pii: E1734. doi: 10.3390/jcm8101734.


Antiangiogenic Effect of Isomalyngamide A Riboside CY01 in Breast Cancer Cells via Inhibition of Migration, Tube Formation and pVEGFR2/pAKT Signals.

Shih CY, Chang TT, Chen CL, Li WS.

Anticancer Agents Med Chem. 2019 Oct 19. doi: 10.2174/1871520619666191019123244. [Epub ahead of print]


Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore.

Wu D, Dou J, Chai X, Bellis C, Wilm A, Shih CC, Soon WWJ, Bertin N, Lin CB, Khor CC, DeGiorgio M, Cheng S, Bao L, Karnani N, Hwang WYK, Davila S, Tan P, Shabbir A, Moh A, Tan EK, Foo JN, Goh LL, Leong KP, Foo RSY, Lam CSP, Richards AM, Cheng CY, Aung T, Wong TY, Ng HH; SG10K Consortium, Liu J, Wang C.

Cell. 2019 Oct 17;179(3):736-749.e15. doi: 10.1016/j.cell.2019.09.019.


Efficacy and Safety of Extracorporeal Shockwave Therapy for Treatment of Knee Osteoarthritis: A Systematic Review and Meta-analysis.

Wang YC, Huang HT, Huang PJ, Liu ZM, Shih CL.

Pain Med. 2019 Oct 18. pii: pnz262. doi: 10.1093/pm/pnz262. [Epub ahead of print]


Multilevel Photonic Transistor Memory Devices Using Conjugated/Insulated Polymer Blend Electrets.

Shih CC, Chiang YC, Hsieh HC, Lin YC, Chen WC.

ACS Appl Mater Interfaces. 2019 Nov 13;11(45):42429-42437. doi: 10.1021/acsami.9b14628. Epub 2019 Oct 30.


Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly.

Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ.

MBio. 2019 Oct 15;10(5). pii: e02447-19. doi: 10.1128/mBio.02447-19.


Hypnotic Effects of Lactobacillus fermentum PS150TM on Pentobarbital-Induced Sleep in Mice.

Lin A, Shih CT, Huang CL, Wu CC, Lin CT, Tsai YC.

Nutrients. 2019 Oct 9;11(10). pii: E2409. doi: 10.3390/nu11102409.


Assessing the Similarity between Random Copolymer Drug Glatiramer Acetate by Using LC-MS Data Coupling with Hypothesis Testing.

Wu HY, Ma MC, Pan YY, Shih CL, Zgoda V, Li CS, Lin LC, Liao PC.

Anal Chem. 2019 Nov 1. doi: 10.1021/acs.analchem.9b02488. [Epub ahead of print]


Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta.

Pan CH, Chen CJ, Shih CM, Wang MF, Wang JY, Wu CH.

Aging (Albany NY). 2019 Oct 3;11(19):8085-8102. doi: 10.18632/aging.102270. Epub 2019 Oct 3.


Study protocol for a prospective observational study to investigate the role of luminal pressure on arteriovenous fistula maturation.

Cheng HS, Chang TI, Chen CH, Hsu SC, Hsieh HL, Chen CY, Huang WC, Sue YM, Lin FY, Shih CM, Chen JW, Lin SJ, Huang PH, Liu CT.

Medicine (Baltimore). 2019 Oct;98(40):e17238. doi: 10.1097/MD.0000000000017238.


Investigation of the Capacitance-Voltage Electrical Characteristics of Thin-Film Transistors Caused by Hydrogen Diffusion under Negative Bias Stress in a Moist Environment.

Chen HC, Kuo CW, Chang TC, Lai WC, Chen PH, Chen GF, Huang SP, Chen JJ, Zhou KJ, Shih CC, Tsao YC, Huang HC, Sze SM.

ACS Appl Mater Interfaces. 2019 Oct 30;11(43):40196-40203. doi: 10.1021/acsami.9b11637. Epub 2019 Oct 15.


Ocular and orbital exacerbation after rituximab therapy for granulomatosis with polyangiitis.

Shih CB, Wang YC, Lai CC.

Can J Ophthalmol. 2019 Oct;54(5):e237-e241. doi: 10.1016/j.jcjo.2018.12.004. Epub 2019 Jan 23. No abstract available.


Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress.

Tung TH, Tung YT, Lin IH, Shih CK, Nguyen NTK, Shabrina A, Huang SY.

Biomolecules. 2019 Sep 21;9(10). pii: E516. doi: 10.3390/biom9100516.


Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity.

Guang Y, McGrath TM, Klug N, Nims R, Shih CC, Bayguinov PO, Guilak F, Pham CTN, Fitzpatrick JAJ, Setton LA.

J Biomech Eng. 2019 Sep 1. doi: 10.1115/1.4044892. [Epub ahead of print]


The effect of visuospatial resolution on discharge variability among motor units and force-discharge relation.

Chen YC, Shih CL, Lin YT, Hwang IS.

Chin J Physiol. 2019 Jul-Aug;62(4):166-174. doi: 10.4103/CJP.CJP_12_19.


Djulis (Chenopodium Formosanum) Prevents Colon Carcinogenesis via Regulating Antioxidative and Apoptotic Pathways in Rats.

Lee CW, Chen HJ, Xie GR, Shih CK.

Nutrients. 2019 Sep 10;11(9). pii: E2168. doi: 10.3390/nu11092168.


Phytochrome coordinates with a hnRNP to regulate alternative splicing via an exonic splicing silencer.

Lin BY, Shih CJ, Hsieh HY, Chen HC, Tu SL.

Plant Physiol. 2019 Sep 9. pii: pp.00289.2019. doi: 10.1104/pp.19.00289. [Epub ahead of print]


Factors in ProGlide® Vascular Closure Failure in Sheath Arteriotomies Greater than 16 French.

Chen IM, Lee TH, Chen PL, Shih CC, Chang HH.

Eur J Vasc Endovasc Surg. 2019 Oct;58(4):615-622. doi: 10.1016/j.ejvs.2019.03.037. Epub 2019 Sep 6.


Characterization of hand tendons through high-frequency ultrasound elastography.

Chen PY, Yang TH, Kuo LC, Shih CC, Huang CC.

IEEE Trans Ultrason Ferroelectr Freq Control. 2019 Aug 28. doi: 10.1109/TUFFC.2019.2938147. [Epub ahead of print]


Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model.

Wu SY, Chang YS, Chu TH, Shih C.

J Virol. 2019 Oct 29;93(22). pii: e01001-19. doi: 10.1128/JVI.01001-19. Print 2019 Nov 15.


Cretaceous winged stick insects clarify the early evolution of Phasmatodea.

Yang H, Yin X, Lin X, Wang C, Shih C, Zhang W, Ren D, Gao T.

Proc Biol Sci. 2019 Aug 28;286(1909):20191085. doi: 10.1098/rspb.2019.1085. Epub 2019 Aug 21.


Macroscopic Salt Rejection through Electrostatically Gated Nanoporous Graphene.

Wyss RM, Tian T, Yazda K, Park HG, Shih CJ.

Nano Lett. 2019 Sep 11;19(9):6400-6409. doi: 10.1021/acs.nanolett.9b02579. Epub 2019 Aug 30.


Frontal Sinus Transillumination in Cranioplasty for Facial Feminization Surgery.

Gilde JE, Shih CW, Kleinberger AJ.

JAMA Facial Plast Surg. 2019 Aug 15. doi: 10.1001/jamafacial.2019.0606. [Epub ahead of print] No abstract available.


Heterogeneous Nuclear Ribonucleoprotein H1 Coordinates with Phytochrome and the U1 snRNP Complex to Regulate Alternative Splicing in Physcomitrella patens.

Shih CJ, Chen HW, Hsieh HY, Lai YH, Chiu FY, Chen YR, Tu SL.

Plant Cell. 2019 Oct;31(10):2510-2524. doi: 10.1105/tpc.19.00314. Epub 2019 Aug 13.


Factors Associated with Access of Marital Migrants and Migrant Workers to Healthcare in Taiwan: A Questionnaire Survey with Quantitative Analysis.

Chu FY, Chang HT, Shih CL, Jeng CJ, Chen TJ, Lee WC.

Int J Environ Res Public Health. 2019 Aug 8;16(16). pii: E2830. doi: 10.3390/ijerph16162830.


miR-140 targeting CTSB signaling suppresses the mesenchymal transition and enhances temozolomide cytotoxicity in glioblastoma multiforme.

Ho KH, Cheng CH, Chou CM, Chen PH, Liu AJ, Lin CW, Shih CM, Chen KC.

Pharmacol Res. 2019 Sep;147:104390. doi: 10.1016/j.phrs.2019.104390. Epub 2019 Aug 6.


Seroepidemiology of Hepatitis B Virus Infection in Native and Immigrant Pregnant Women: A 20-Year Retrospective Study in Taiwan.

Lin CC, Shih CT, Lee CH, Ku MK, Huang YL.

Am J Trop Med Hyg. 2019 Oct;101(4):899-904. doi: 10.4269/ajtmh.19-0088.


Serum fibroblast growth factor 23 and mineral metabolism in patients with euthyroid Graves' diseases: a case-control study.

Lin CH, Chang CK, Shih CW, Li HY, Chen KY, Yang WS, Tsai KS, Wang CY, Shih SR.

Osteoporos Int. 2019 Nov;30(11):2289-2297. doi: 10.1007/s00198-019-05116-1. Epub 2019 Aug 5.


Acute Myocardial Infarction Hospitalizations between Cold and Hot Seasons in an Island across Tropical and Subtropical Climate Zones-A Population-Based Study.

Chu ML, Shih CY, Hsieh TC, Chen HL, Lee CW, Hsieh JC.

Int J Environ Res Public Health. 2019 Aug 2;16(15). pii: E2769. doi: 10.3390/ijerph16152769.


Dietary Glycotoxins, Advanced Glycation End Products, Inhibit Cell Proliferation and Progesterone Secretion in Ovarian Granulosa Cells and Mimic PCOS-like Symptoms.

Lin PH, Chang CC, Wu KH, Shih CK, Chiang W, Chen HY, Shih YH, Wang KL, Hong YH, Shieh TM, Hsia SM.

Biomolecules. 2019 Jul 31;9(8). pii: E327. doi: 10.3390/biom9080327.


Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model.

Chang CS, Liao CC, Liou AT, Chang YS, Chang YT, Tzeng BH, Chen CC, Shih C.

Sci Rep. 2019 Jul 31;9(1):11108. doi: 10.1038/s41598-019-47455-3.


Tailor-made iliac branched device for preserving the internal iliac artery in patients with common iliac artery aneurysm.

Chen PL, Hsu HL, Chen IM, Kuo TT, Chen YY, Shih CC.

J Chin Med Assoc. 2019 Sep;82(9):710-713. doi: 10.1097/JCMA.0000000000000156.


Determination of phenylenediamines in hair colors derivatizated with 5-(4, 6-dichlorotriazinyl)aminofluorescein via micellar electrokinetic chromatography.

Ko HY, Lin YH, Shih CJ, Chen YL.

J Food Drug Anal. 2019 Jul;27(3):825-831. doi: 10.1016/j.jfda.2019.02.005. Epub 2019 Mar 21.


Focused Ultrasound Assists in Diagnosis and Management of Difficult Airway in Ludwig's Angina.

Shih CC, Wang JC, Chen SJ, Hsu YP.

J Med Ultrasound. 2019 Apr-Jun;27(2):101-103. doi: 10.4103/JMU.JMU_95_18. Epub 2019 Jan 8.


Comparison of implant failure rates of different plates for midshaft clavicular fractures based on fracture classifications.

Chiu YC, Huang KC, Shih CM, Lee KT, Chen KH, Hsu CE.

J Orthop Surg Res. 2019 Jul 16;14(1):220. doi: 10.1186/s13018-019-1259-x.


Insulin Resistance and Cardiovascular Risks in Different Groups of Hemodialysis Patients: A Multicenter Study.

Duong TV, Shih CK, Wong TC, Chen HH, Chen TH, Hsu YH, Peng SJ, Kuo KL, Liu HC, Lin ET, Su CT, Yang SH.

Biomed Res Int. 2019 Jun 11;2019:1541593. doi: 10.1155/2019/1541593. eCollection 2019.


BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine.

Chao PK, Chang HF, Chang WT, Yeh TK, Ou LC, Chuang JY, Tsu-An Hsu J, Tao PL, Loh HH, Shih C, Ueng SH, Yeh SH.

Neuropharmacology. 2019 Jul 3:107678. doi: 10.1016/j.neuropharm.2019.107678. [Epub ahead of print]


Correction: Risk of Obstructive Sleep Apnea in Adult Patients with Asthma: A Population-Based Cohort Study in Taiwan.

Shen TC, Lin CL, Wei CC, Chen CH, Tu CY, Hsia TC, Shih CM, Hsu WH, Sung FC, Kao CH.

PLoS One. 2019 Jul 5;14(7):e0219612. doi: 10.1371/journal.pone.0219612. eCollection 2019.

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