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Items: 49

1.

A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations.

Zyba SJ, Shenvi SV, Killilea DW, Holland TC, Kim E, Moy A, Sutherland B, Gildengorin V, Shigenaga MK, King JC.

Am J Clin Nutr. 2017 Feb;105(2):343-351. doi: 10.3945/ajcn.116.135327. Epub 2016 Dec 21. Erratum in: Am J Clin Nutr. 2017 Dec;106(6):1539.

2.

A multicomponent nutrient bar promotes weight loss and improves dyslipidemia and insulin resistance in the overweight/obese: chronic inflammation blunts these improvements.

McCann JC, Shigenaga MK, Mietus-Snyder ML, Lal A, Suh JH, Krauss RM, Gildengorin GL, Goldrich AM, Block DS, Shenvi SV, McHugh TH, Olson DA, Ames BN.

FASEB J. 2015 Aug;29(8):3287-301. doi: 10.1096/fj.15-271833. Epub 2015 Apr 21.

PMID:
25900806
3.

Compared to sucrose, previous consumption of fructose and glucose monosaccharides reduces survival and fitness of female mice.

Ruff JS, Hugentobler SA, Suchy AK, Sosa MM, Tanner RE, Hite ME, Morrison LC, Gieng SH, Shigenaga MK, Potts WK.

J Nutr. 2015 Mar;145(3):434-41. doi: 10.3945/jn.114.202531. Epub 2014 Dec 10.

4.

Human-relevant levels of added sugar consumption increase female mortality and lower male fitness in mice.

Ruff JS, Suchy AK, Hugentobler SA, Sosa MM, Schwartz BL, Morrison LC, Gieng SH, Shigenaga MK, Potts WK.

Nat Commun. 2013;4:2245. doi: 10.1038/ncomms3245.

5.

Biomarkers of oxidative stress study V: ozone exposure of rats and its effect on lipids, proteins, and DNA in plasma and urine.

Kadiiska MB, Basu S, Brot N, Cooper C, Saari Csallany A, Davies MJ, George MM, Murray DM, Jackson Roberts L 2nd, Shigenaga MK, Sohal RS, Stocker R, Van Thiel DH, Wiswedel I, Hatch GE, Mason RP.

Free Radic Biol Med. 2013 Aug;61:408-15. doi: 10.1016/j.freeradbiomed.2013.04.023. Epub 2013 Apr 19.

6.

A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial.

Mietus-Snyder ML, Shigenaga MK, Suh JH, Shenvi SV, Lal A, McHugh T, Olson D, Lilienstein J, Krauss RM, Gildengoren G, McCann JC, Ames BN.

FASEB J. 2012 Aug;26(8):3515-27. doi: 10.1096/fj.11-201558. Epub 2012 May 1.

7.

The anti-tumor effects of calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas.

Mahlke MA, Cortez LA, Ortiz MA, Rodriguez M, Uchida K, Shigenaga MK, Lee S, Zhang Y, Tominaga K, Hubbard GB, Ikeno Y.

Pathobiol Aging Age Relat Dis. 2011;1. doi: 10.3402/pba.v1i0.7189. Epub 2011 Jun 1.

8.

Clinical assay of four thiol amino acid redox couples by LC-MS/MS: utility in thalassemia.

Suh JH, Kim R, Yavuz B, Lee D, Lal A, Ames BN, Shigenaga MK.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 15;877(28):3418-27. doi: 10.1016/j.jchromb.2009.06.041. Epub 2009 Jul 2.

9.
10.

Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning.

Kadiiska MB, Gladen BC, Baird DD, Graham LB, Parker CE, Ames BN, Basu S, Fitzgerald GA, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ 2nd, Rokach J, Shigenaga MK, Sun J, Walter PB, Tomer KB, Barrett JC, Mason RP.

Free Radic Biol Med. 2005 Mar 15;38(6):711-8.

PMID:
15721981
11.

Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, Hatch GE, Hensley K, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ 2nd, Rokach J, Shigenaga MK, Sohal RS, Sun J, Tice RR, Van Thiel DH, Wellner D, Walter PB, Tomer KB, Mason RP, Barrett JC.

Free Radic Biol Med. 2005 Mar 15;38(6):698-710.

PMID:
15721980
13.

The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms.

Nukui M, Taylor KB, McPherson DT, Shigenaga MK, Jedrzejas MJ.

J Biol Chem. 2003 Jan 31;278(5):3079-88. Epub 2002 Nov 21.

14.

Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation.

Jiang Q, Lykkesfeldt J, Shigenaga MK, Shigeno ET, Christen S, Ames BN.

Free Radic Biol Med. 2002 Dec 1;33(11):1534-42.

PMID:
12446211
15.
16.

Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig.

Halsted CH, Villanueva JA, Devlin AM, Niemelä O, Parkkila S, Garrow TA, Wallock LM, Shigenaga MK, Melnyk S, James SJ.

Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10072-7. Epub 2002 Jul 16.

17.

Immunodetection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC.

Girault I, Karu AE, Schaper M, Barcellos-Hoff MH, Hagen T, Vogel DS, Ames BN, Christen S, Shigenaga MK.

Free Radic Biol Med. 2001 Dec 1;31(11):1375-87.

PMID:
11728809
18.

gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention.

Jiang Q, Christen S, Shigenaga MK, Ames BN.

Am J Clin Nutr. 2001 Dec;74(6):714-22. Review.

PMID:
11722951
19.

Myeloperoxidase and protein oxidation in cystic fibrosis.

Van Der Vliet A, Nguyen MN, Shigenaga MK, Eiserich JP, Marelich GP, Cross CE.

Am J Physiol Lung Cell Mol Physiol. 2000 Sep;279(3):L537-46.

20.

Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs.

Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ 2nd, Wynshaw-Boris A, Levine RL.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9915-9.

21.

Reactive nitrogen species and tyrosine nitration in the respiratory tract: epiphenomena or a pathobiologic mechanism of disease?

van der Vliet A, Eiserich JP, Shigenaga MK, Cross CE.

Am J Respir Crit Care Med. 1999 Jul;160(1):1-9. Review. No abstract available.

PMID:
10390372
22.
23.

DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine.

Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, Ames BN.

Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):288-93.

24.

'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status.

MacGregor JT, Wehr CM, Hiatt RA, Peters B, Tucker JD, Langlois RG, Jacob RA, Jensen RH, Yager JW, Shigenaga MK, Frei B, Eynon BP, Ames BN.

Mutat Res. 1997 Jun 9;377(1):125-35.

PMID:
9219587
25.

gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications.

Christen S, Woodall AA, Shigenaga MK, Southwell-Keely PT, Duncan MW, Ames BN.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3217-22.

26.

Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection.

Shigenaga MK, Lee HH, Blount BC, Christen S, Shigeno ET, Yip H, Ames BN.

Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3211-6.

27.

Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats.

Liu J, Wang X, Shigenaga MK, Yeo HC, Mori A, Ames BN.

FASEB J. 1996 Nov;10(13):1532-8.

PMID:
8940299
28.

Cancer prevention, rodent high-dose cancer tests, and risk assessment.

Ames BN, Gold LS, Shigenaga MK.

Risk Anal. 1996 Oct;16(5):613-7. Review. No abstract available.

PMID:
8962512
29.

Antioxidant activity of diethyldithiocarbamate.

Liu J, Shigenaga MK, Yan LJ, Mori A, Ames BN.

Free Radic Res. 1996 Jun;24(6):461-72.

PMID:
8804989
30.
31.

Mitochondrial decay in aging.

Ames BN, Shigenaga MK, Hagen TM.

Biochim Biophys Acta. 1995 May 24;1271(1):165-70. Review.

32.

Oxidative damage and mitochondrial decay in aging.

Shigenaga MK, Hagen TM, Ames BN.

Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10771-8. Review.

34.

DNA lesions, inducible DNA repair, and cell division: three key factors in mutagenesis and carcinogenesis.

Ames BN, Shigenaga MK, Gold LS.

Environ Health Perspect. 1993 Dec;101 Suppl 5:35-44. Review.

35.

Oxidants, antioxidants, and the degenerative diseases of aging.

Ames BN, Shigenaga MK, Hagen TM.

Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):7915-22. Review.

36.

Maternal dietary zinc influences DNA strand break and 8-hydroxy-2'-deoxyguanosine levels in infant rhesus monkey liver.

Olin KL, Shigenaga MK, Ames BN, Golub MS, Gershwin ME, Hendrickx AG, Keen CL.

Proc Soc Exp Biol Med. 1993 Sep;203(4):461-6.

PMID:
8351286
37.

Antioxidant status and indexes of oxidative stress during consecutive days of exercise.

Viguie CA, Frei B, Shigenaga MK, Ames BN, Packer L, Brooks GA.

J Appl Physiol (1985). 1993 Aug;75(2):566-72.

PMID:
7693646
38.

Oxidants and mitogenesis as causes of mutation and cancer: the influence of diet.

Shigenaga MK, Ames BN.

Basic Life Sci. 1993;61:419-36. Review.

PMID:
8304950
39.

Oxidants are a major contributor to aging.

Ames BN, Shigenaga MK.

Ann N Y Acad Sci. 1992 Nov 21;663:85-96. Review.

PMID:
1482105
40.

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

Park EM, Shigenaga MK, Degan P, Korn TS, Kitzler JW, Wehr CM, Kolachana P, Ames BN.

Proc Natl Acad Sci U S A. 1992 Apr 15;89(8):3375-9.

41.

Ascorbic acid protects against endogenous oxidative DNA damage in human sperm.

Fraga CG, Motchnik PA, Shigenaga MK, Helbock HJ, Jacob RA, Ames BN.

Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11003-6.

42.
43.

Assays for 8-hydroxy-2'-deoxyguanosine: a biomarker of in vivo oxidative DNA damage.

Shigenaga MK, Ames BN.

Free Radic Biol Med. 1991;10(3-4):211-6.

PMID:
1650737
44.

The role of cytochromes P-450 and flavin-containing monooxygenase in the metabolism of (S)-nicotine by rabbit lung.

Williams DE, Shigenaga MK, Castagnoli N Jr.

Drug Metab Dispos. 1990 Jul-Aug;18(4):418-28.

PMID:
1976062
45.

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

Fraga CG, Shigenaga MK, Park JW, Degan P, Ames BN.

Proc Natl Acad Sci U S A. 1990 Jun;87(12):4533-7.

46.
47.

Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

Shigenaga MK, Gimeno CJ, Ames BN.

Proc Natl Acad Sci U S A. 1989 Dec;86(24):9697-701.

48.

Liver and lung microsomal metabolism of the tobacco alkaloid beta-nicotyrine.

Shigenaga MK, Kim BH, Caldera-Munoz P, Cairns T, Jacob P 3rd, Trevor AJ, Castagnoli N Jr.

Chem Res Toxicol. 1989 Sep-Oct;2(5):282-7.

PMID:
2519819
49.

Metabolism-dependent covalent binding of (S)-[5-3H]nicotine to liver and lung microsomal macromolecules.

Shigenaga MK, Trevor AJ, Castagnoli N Jr.

Drug Metab Dispos. 1988 May-Jun;16(3):397-402.

PMID:
2900731

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