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Dynamic response of microglia/macrophage polarization following demyelination in mice.

Chu T, Zhang YP, Tian Z, Ye C, Zhu M, Shields LBE, Kong M, Barnes GN, Shields CB, Cai J.

J Neuroinflammation. 2019 Oct 17;16(1):188. doi: 10.1186/s12974-019-1586-1.


Missed thoracic myelopathy: Do not throw the hammer away yet.

Shields LBE, Iyer VG, Zhang YP, Shields CB.

Surg Neurol Int. 2019 Aug 9;10:158. doi: 10.25259/SNI_352_2019. eCollection 2019.


Pipeline Embolization Device for Treatment of Craniocervical Internal Carotid Artery Dissections: Report of 3 Cases.

Shields LBE, Shields CB, Ghiassi M, Dashti SR, Yao TL, Zhang YP, Ghiassi M.

World Neurosurg. 2019 Sep 3;132:106-112. doi: 10.1016/j.wneu.2019.08.183. [Epub ahead of print]


Inhibitor of DNA binding 2 promotes axonal growth through upregulation of Neurogenin2.

Huang Z, Liu J, Jin J, Chen Q, Shields LBE, Zhang YP, Shields CB, Zhou L, Zhou B, Yu P.

Exp Neurol. 2019 Oct;320:112966. doi: 10.1016/j.expneurol.2019.112966. Epub 2019 May 28.


Endovascular Treatment for Venous Sinus Stenosis in Idiopathic Intracranial Hypertension: An Observational Study of Clinical Indications, Surgical Technique, and Long-Term Outcomes.

Shields LBE, Shields CB, Yao TL, Plato BM, Zhang YP, Dashti SR.

World Neurosurg. 2019 Jan;121:e165-e171. doi: 10.1016/j.wneu.2018.09.070. Epub 2018 Sep 21.


Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery.

Wang Y, Wu W, Wu X, Sun Y, Zhang YP, Deng LX, Walker MJ, Qu W, Chen C, Liu NK, Han Q, Dai H, Shields LB, Shields CB, Sengelaub DR, Jones KJ, Smith GM, Xu XM.

Elife. 2018 Sep 12;7. pii: e39016. doi: 10.7554/eLife.39016.


A Laser-Guided Spinal Cord Displacement Injury in Adult Mice.

Wu X, Qu W, Bakare AA, Zhang YP, Fry CME, Shields LBE, Shields CB, Xu XM.

J Neurotrauma. 2019 Feb 1;36(3):460-468. doi: 10.1089/neu.2018.5756. Epub 2018 Aug 13.


A Hospital-Based Neuroscience Nursing Course Designed to Improve Competence and Confidence.

Shields LBE, Perkins L, Clark L, Shields CB.

J Nurs Adm. 2018 Jun;48(6):300-302. doi: 10.1097/NNA.0000000000000618.


Acute cauda equina syndrome following orthopedic procedures as a result of epidural anesthesia.

Shields LBE, Iyer VG, Zhang YP, Shields CB.

Surg Neurol Int. 2018 Apr 10;9:81. doi: 10.4103/sni.sni_492_17. eCollection 2018.


An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury.

Chen C, Zhang YP, Sun Y, Xiong W, Shields LBE, Shields CB, Jin X, Xu XM.

J Vis Exp. 2017 Dec 31;(130). doi: 10.3791/56565.


CXCL12/CXCR4/CXCR7 Chemokine Axis in the Central Nervous System: Therapeutic Targets for Remyelination in Demyelinating Diseases.

Chu T, Shields LBE, Zhang YP, Feng SQ, Shields CB, Cai J.

Neuroscientist. 2017 Dec;23(6):627-648. doi: 10.1177/1073858416685690. Epub 2017 Jan 10. Review.


Enriched physical environment reverses spatial cognitive impairment of socially isolated APPswe/PS1dE9 transgenic mice before amyloidosis onset.

Cao M, Hu PP, Zhang YL, Yan YX, Shields CB, Zhang YP, Hu G, Xiao M.

CNS Neurosci Ther. 2018 Mar;24(3):202-211. doi: 10.1111/cns.12790. Epub 2017 Dec 23.


Pathophysiological and behavioral deficits in developing mice following rotational acceleration-deceleration traumatic brain injury.

Wang G, Zhang YP, Gao Z, Shields LBE, Li F, Chu T, Lv H, Moriarty T, Xu XM, Yang X, Shields CB, Cai J.

Dis Model Mech. 2018 Jan 30;11(1). pii: dmm030387. doi: 10.1242/dmm.030387.


A Tissue Displacement-based Contusive Spinal Cord Injury Model in Mice.

Wu X, Zhang YP, Qu W, Shields LBE, Shields CB, Xu XM.

J Vis Exp. 2017 Jun 18;(124). doi: 10.3791/54988.


Decreasing hospital length of stay following lumbar fusion utilizing multidisciplinary committee meetings involving surgeons and other caretakers.

Shields LB, Clark L, Glassman SD, Shields CB.

Surg Neurol Int. 2017 Jan 19;8:5. doi: 10.4103/2152-7806.198732. eCollection 2017.


Posterior reversible encephalopathy syndrome following a thoracic discectomy-induced dural leak: case report.

Shields LB, Johnson JR, Shields CB.

J Neurosurg Spine. 2016 Nov;25(5):586-590. Epub 2016 Jun 3.


Current Understanding of Platelet-Activating Factor Signaling in Central Nervous System Diseases.

Liu Y, Shields LBE, Gao Z, Wang Y, Zhang YP, Chu T, Zhu Q, Shields CB, Cai J.

Mol Neurobiol. 2017 Sep;54(7):5563-5572. doi: 10.1007/s12035-016-0062-5. Epub 2016 Sep 9. Review.


Anatomical and functional effects of lateral cervical hemicontusion in adult rats.

Walker CL, Zhang YP, Liu Y, Li Y, Walker MJ, Liu NK, Shields CB, Xu XM.

Restor Neurol Neurosci. 2016 May 2;34(3):389-400. doi: 10.3233/RNN-150597.


A controlled spinal cord contusion for the rhesus macaque monkey.

Ma Z, Zhang YP, Liu W, Yan G, Li Y, Shields LBE, Walker M, Chen K, Huang W, Kong M, Lu Y, Brommer B, Chen X, Xu XM, Shields CB.

Exp Neurol. 2016 May;279:261-273. doi: 10.1016/j.expneurol.2016.02.008. Epub 2016 Feb 11.


A Compact Blast-Induced Traumatic Brain Injury Model in Mice.

Wang H, Zhang YP, Cai J, Shields LB, Tuchek CA, Shi R, Li J, Shields CB, Xu XM.

J Neuropathol Exp Neurol. 2016 Feb;75(2):183-96.


Thermal nociception using a modified Hargreaves method in primates and humans.

Ma Z, Li Y, Zhang YP, Shields LB, Xie Q, Yan G, Liu W, Chen G, Zhang Y, Brommer B, Xu XM, Lu Y, Chen X, Shields CB.

Funct Neurol. 2015 Oct-Dec;30(4):229-36.


Developmental expression and function analysis of protein tyrosine phosphatase receptor type D in oligodendrocyte myelination.

Zhu Q, Tan Z, Zhao S, Huang H, Zhao X, Hu X, Zhang Y, Shields CB, Uetani N, Qiu M.

Neuroscience. 2015 Nov 12;308:106-14. doi: 10.1016/j.neuroscience.2015.08.062. Epub 2015 Sep 1.


The Art of Intraoperative Glioma Identification.

Zhang ZZ, Shields LB, Sun DA, Zhang YP, Hunt MA, Shields CB.

Front Oncol. 2015 Jul 30;5:175. doi: 10.3389/fonc.2015.00175. eCollection 2015. Review.


Treadmill training induced lumbar motoneuron dendritic plasticity and behavior recovery in adult rats after a thoracic contusive spinal cord injury.

Wang H, Liu NK, Zhang YP, Deng L, Lu QB, Shields CB, Walker MJ, Li J, Xu XM.

Exp Neurol. 2015 Sep;271:368-78. doi: 10.1016/j.expneurol.2015.07.004. Epub 2015 Jul 9.


Attenuated Reactive Gliosis and Enhanced Functional Recovery Following Spinal Cord Injury in Null Mutant Mice of Platelet-Activating Factor Receptor.

Wang Y, Gao Z, Zhang Y, Feng SQ, Liu Y, Shields LBE, Zhao YZ, Zhu Q, Gozal D, Shields CB, Cai J.

Mol Neurobiol. 2016 Jul;53(5):3448-3461. doi: 10.1007/s12035-015-9263-6. Epub 2015 Jun 18.


BAER suppression during posterior fossa dural opening.

Shields CB, Shields LB, Jiang YD, Yao T, Zhang YP, Sun DA.

Surg Neurol Int. 2015 Apr 9;6:57. doi: 10.4103/2152-7806.154775. eCollection 2015.


Inhibition of LINGO-1 promotes functional recovery after experimental spinal cord demyelination.

Zhang Y, Zhang YP, Pepinsky B, Huang G, Shields LB, Shields CB, Mi S.

Exp Neurol. 2015 Apr;266:68-73. doi: 10.1016/j.expneurol.2015.02.006. Epub 2015 Feb 11.


A novel vertebral stabilization method for producing contusive spinal cord injury.

Walker MJ, Walker CL, Zhang YP, Shields LB, Shields CB, Xu XM.

J Vis Exp. 2015 Jan 5;(95):e50149. doi: 10.3791/50149.


Technical comments on rodent spinal cord injuries models.

Zhang Z, Zhang YP, Shields LB, Shields CB.

Neural Regen Res. 2014 Mar 1;9(5):453-5. doi: 10.4103/1673-5374.130052. No abstract available.


A semicircular controlled cortical impact produces long-term motor and cognitive dysfunction that correlates well with damage to both the sensorimotor cortex and hippocampus.

Liu NK, Zhang YP, Zou J, Verhovshek T, Chen C, Lu QB, Walker CL, Shields CB, Xu XM.

Brain Res. 2014 Aug 12;1576:18-26. doi: 10.1016/j.brainres.2014.05.042. Epub 2014 Jun 4.


Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injury.

Liu NK, Deng LX, Zhang YP, Lu QB, Wang XF, Hu JG, Oakes E, Bonventre JV, Shields CB, Xu XM.

Ann Neurol. 2014 May;75(5):644-58. doi: 10.1002/ana.24134. Epub 2014 Apr 2.


Traumatic brain injury using mouse models.

Zhang YP, Cai J, Shields LB, Liu N, Xu XM, Shields CB.

Transl Stroke Res. 2014 Aug;5(4):454-71. doi: 10.1007/s12975-014-0327-0. Epub 2014 Feb 5. Review.


Aquaporin-4 mitigates retrograde degeneration of rubrospinal neurons by facilitating edema clearance and glial scar formation after spinal cord injury in mice.

Wu Q, Zhang YJ, Gao JY, Li XM, Kong H, Zhang YP, Xiao M, Shields CB, Hu G.

Mol Neurobiol. 2014 Jun;49(3):1327-37. doi: 10.1007/s12035-013-8607-3. Epub 2014 Jan 4.


Correlation between electrophysiological properties, morphological maturation, and olig gene changes during postnatal motor tract development.

Cai J, Zhang YP, Shields LB, Zhang ZZ, Liu N, Xu XM, Feng SQ, Shields CB.

Dev Neurobiol. 2013 Sep;73(9):713-22. doi: 10.1002/dneu.22094. Epub 2013 Jul 19.


Controlled cervical laceration injury in mice.

Zhang YP, Walker MJ, Shields LB, Wang X, Walker CL, Xu XM, Shields CB.

J Vis Exp. 2013 May 9;(75):e50030. doi: 10.3791/50030.


Reciprocal modulation between microglia and astrocyte in reactive gliosis following the CNS injury.

Gao Z, Zhu Q, Zhang Y, Zhao Y, Cai L, Shields CB, Cai J.

Mol Neurobiol. 2013 Dec;48(3):690-701. doi: 10.1007/s12035-013-8460-4. Epub 2013 Apr 24. Review.


Apolipoprotein E Mimetic Promotes Functional and Histological Recovery in Lysolecithin-Induced Spinal Cord Demyelination in Mice.

Gu Z, Li F, Zhang YP, Shields LB, Hu X, Zheng Y, Yu P, Zhang Y, Cai J, Vitek MP, Shields CB.

J Neurol Neurophysiol. 2013 Apr;2014(Suppl 12):10.


A bilateral head injury that shows graded brain damage and behavioral deficits in adultmice.

Liu NK, Zhang YP, O'Connor J, Gianaris A, Oakes E, Lu QB, Verhovshek T, Walker CL, Shields CB, Xu XM.

Brain Res. 2013 Mar 7;1499:121-8. doi: 10.1016/j.brainres.2012.12.031. Epub 2012 Dec 28.


Post-traumatic syringomyelia: CSF hydrodynamic changes following spinal cord injury are the driving force in the development of PTSM.

Shields CB, Zhang YP, Shields LB.

Handb Clin Neurol. 2012;109:355-67. doi: 10.1016/B978-0-444-52137-8.00022-X.


Intrathecal treatment of cerebral vasospasm.

Zhang YP, Shields LB, Yao TL, Dashti SR, Shields CB.

J Stroke Cerebrovasc Dis. 2013 Nov;22(8):1201-11. doi: 10.1016/j.jstrokecerebrovasdis.2012.04.005. Epub 2012 May 30. Review.


Kr├╝ppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract.

Blackmore MG, Wang Z, Lerch JK, Motti D, Zhang YP, Shields CB, Lee JK, Goldberg JL, Lemmon VP, Bixby JL.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7517-22. doi: 10.1073/pnas.1120684109. Epub 2012 Apr 23.


Cervical central canal occlusion induces noncommunicating syringomyelia.

Zhang Y, Zhang YP, Shields LB, Zheng Y, Xu XM, Whittemore SR, Shields CB.

Neurosurgery. 2012 Jul;71(1):126-37. doi: 10.1227/NEU.0b013e31824d18ae.


Characterizing phospholipase A2-induced spinal cord injury-a comparison with contusive spinal cord injury in adult rats.

Liu NK, Titsworth WL, Zhang YP, Xhafa AI, Shields CB, Xu XM.

Transl Stroke Res. 2011 Dec 1;2(4):608-18. doi: 10.1007/s12975-011-0089-x.


Malignant psammomatous melanotic schwannoma of the spine: A component of Carney complex.

Shields LB, Glassman SD, Raque GH, Shields CB.

Surg Neurol Int. 2011;2:136. doi: 10.4103/2152-7806.85609. Epub 2011 Sep 30.


Mouse intermittent hypoxia mimicking apnoea of prematurity: effects on myelinogenesis and axonal maturation.

Cai J, Tuong CM, Zhang Y, Shields CB, Guo G, Fu H, Gozal D.

J Pathol. 2012 Feb;226(3):495-508. doi: 10.1002/path.2980. Epub 2011 Oct 18.


Deletion of the pro-apoptotic endoplasmic reticulum stress response effector CHOP does not result in improved locomotor function after severe contusive spinal cord injury.

Ohri SS, Maddie MA, Zhang Y, Shields CB, Hetman M, Whittemore SR.

J Neurotrauma. 2012 Feb 10;29(3):579-88. doi: 10.1089/neu.2011.1940. Epub 2011 Nov 21.


Inhibitor of DNA binding 2 promotes sensory axonal growth after SCI.

Yu P, Zhang YP, Shields LB, Zheng Y, Hu X, Hill R, Howard R, Gu Z, Burke DA, Whittemore SR, Xu XM, Shields CB.

Exp Neurol. 2011 Sep;231(1):38-44. doi: 10.1016/j.expneurol.2011.05.013. Epub 2011 Jun 12.


Effect of heparin following cervical spinal cord injuries in rats.

Zheng Y, Zhang YP, Shields LB, Zhang Y, Siu MW, Burke DA, Zhu J, Hu X, Dimar JR, Shields CB.

Neurosurgery. 2011 Oct;69(4):930-41; discussion 941. doi: 10.1227/NEU.0b013e3182241f3b.


Enhanced adenoviral gene delivery to motor and dorsal root ganglion neurons following injection into demyelinated peripheral nerves.

Zhang Y, Zheng Y, Zhang YP, Shields LB, Hu X, Yu P, Burke DA, Wang H, Jun C, Byers J, Whittemore SR, Shields CB.

J Neurosci Res. 2010 Aug 15;88(11):2374-84. doi: 10.1002/jnr.22394.


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