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Items: 1 to 50 of 142

1.

Enablers and barriers to treatment adherence in heterozygous familial hypercholesterolaemia: a qualitative evidence synthesis.

Kinnear FJ, Wainwright E, Perry R, Lithander FE, Bayly G, Huntley A, Cox J, Shield JP, Searle A.

BMJ Open. 2019 Jul 31;9(7):e030290. doi: 10.1136/bmjopen-2019-030290.

2.

Associations between physical activity and asthma, eczema and obesity in children aged 12-16: an observational cohort study.

Jago R, Salway RE, Ness AR, Shield JPH, Ridd MJ, Henderson AJ.

BMJ Open. 2019 Jan 20;9(1):e024858. doi: 10.1136/bmjopen-2018-024858.

3.

Treatment adherence and BMI reduction are key predictors of HbA1c 1 year after diagnosis of childhood type 2 diabetes in the United Kingdom.

Candler TP, Mahmoud O, Lynn RM, Majbar AA, Barrett TG, Shield JPH.

Pediatr Diabetes. 2018 Dec;19(8):1393-1399. doi: 10.1111/pedi.12761. Epub 2018 Oct 11.

PMID:
30175430
4.

Continuing rise of Type 2 diabetes incidence in children and young people in the UK.

Candler TP, Mahmoud O, Lynn RM, Majbar AA, Barrett TG, Shield JPH.

Diabet Med. 2018 Jun;35(6):737-744. doi: 10.1111/dme.13609. Epub 2018 Mar 24.

5.

Is Child Abuse Associated with Adolescent Obesity? A Population Cohort Study.

Hawton K, Norris T, Crawley E, Shield JPH.

Child Obes. 2018 Feb/Mar;14(2):106-113. doi: 10.1089/chi.2017.0141. Epub 2017 Dec 20.

PMID:
29260887
6.

Cognitive behavioural therapy stabilises glycaemic control in adolescents with type 1 diabetes-Outcomes from a randomised control trial.

Wei C, Allen RJ, Tallis PM, Ryan FJ, Hunt LP, Shield JP, Crowne EC.

Pediatr Diabetes. 2018 Feb;19(1):106-113. doi: 10.1111/pedi.12519. Epub 2017 Apr 17.

PMID:
28419661
7.

Incidence and Clinical Associations of Childhood Acute Pancreatitis.

Majbar AA, Cusick E, Johnson P, Lynn RM, Hunt LP, Shield JP.

Pediatrics. 2016 Sep;138(3). pii: e20161198. doi: 10.1542/peds.2016-1198. Epub 2016 Aug 17.

8.

A recurrent mitochondrial p.Trp22Arg NDUFB3 variant causes a distinctive facial appearance, short stature and a mild biochemical and clinical phenotype.

Alston CL, Howard C, Oláhová M, Hardy SA, He L, Murray PG, O'Sullivan S, Doherty G, Shield JP, Hargreaves IP, Monavari AA, Knerr I, McCarthy P, Morris AA, Thorburn DR, Prokisch H, Clayton PE, McFarland R, Hughes J, Crushell E, Taylor RW.

J Med Genet. 2016 Sep;53(9):634-41. doi: 10.1136/jmedgenet-2015-103576. Epub 2016 Apr 18.

9.

Hyperglycaemia-induced chemoresistance in breast cancer cells: role of the estrogen receptor.

Zeng L, Zielinska HA, Arshad A, Shield JP, Bahl A, Holly JM, Perks CM.

Endocr Relat Cancer. 2016 Feb;23(2):125-34. doi: 10.1530/ERC-15-0507. Epub 2015 Dec 8.

PMID:
26647383
10.

Attitudes to Exercise and Diabetes in Young People with Type 1 Diabetes Mellitus: A Qualitative Analysis.

Ryninks K, Sutton E, Thomas E, Jago R, Shield JP, Burren CP.

PLoS One. 2015 Oct 14;10(10):e0137562. doi: 10.1371/journal.pone.0137562. eCollection 2015.

11.

Reduced insulin sensitivity in childhood survivors of haematopoietic stem cell transplantation is associated with lipodystropic and sarcopenic phenotypes.

Wei C, Thyagiarajan MS, Hunt LP, Shield JP, Stevens MC, Crowne EC.

Pediatr Blood Cancer. 2015 Nov;62(11):1992-9. doi: 10.1002/pbc.25601. Epub 2015 May 19.

PMID:
25989749
12.

Adolescent experiences of anti-obesity drugs.

White B, Jamieson L, Clifford S, Shield JP, Christie D, Smith F, Wong IC, Viner RM.

Clin Obes. 2015 Jun;5(3):116-26. doi: 10.1111/cob.12101. Epub 2015 May 13.

PMID:
25974187
13.

Insulin and BMI as predictors of adult type 2 diabetes mellitus.

Sabin MA, Magnussen CG, Juonala M, Shield JP, Kähönen M, Lehtimäki T, Rönnemaa T, Koskinen J, Loo BM, Knip M, Hutri-Kähönen N, Viikari JS, Dwyer T, Raitakari OT.

Pediatrics. 2015 Jan;135(1):e144-51. doi: 10.1542/peds.2014-1534. Epub 2014 Dec 22.

14.

Adolescents' views and experiences of treatments for Type 2 diabetes: a qualitative study.

Turner KM, Percival J, Dunger DB, Olbers T, Barrett T, Shield JP.

Diabet Med. 2015 Feb;32(2):250-6. doi: 10.1111/dme.12577. Epub 2014 Oct 1.

PMID:
25186101
15.

Can foster care ever be justified for weight management?

Williams GM, Bredow M, Barton J, Pryce R, Shield JP.

Arch Dis Child. 2014 Mar;99(3):297-9. doi: 10.1136/archdischild-2013-304654. Epub 2013 Nov 13.

PMID:
24225275
16.

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.

Pearce LR, Atanassova N, Banton MC, Bottomley B, van der Klaauw AA, Revelli JP, Hendricks A, Keogh JM, Henning E, Doree D, Jeter-Jones S, Garg S, Bochukova EG, Bounds R, Ashford S, Gayton E, Hindmarsh PC, Shield JP, Crowne E, Barford D, Wareham NJ; UK10K consortium, O'Rahilly S, Murphy MP, Powell DR, Barroso I, Farooqi IS.

Cell. 2013 Nov 7;155(4):765-77.

17.

Longitudinal changes in body mass index following renal transplantation in UK children.

Plumb LA, Pitcher D, Tse Y, Shield JP, Inward C, Sinha MD; British Association for Paediatric Nephrology.

Nephrol Dial Transplant. 2014 Jan;29(1):196-203. doi: 10.1093/ndt/gft395. Epub 2013 Sep 29.

PMID:
24081859
18.

The impact of hyperglycemia on risk of infection and early death during induction therapy for acute lymphoblastic leukemia (ALL).

Dare JM, Moppett JP, Shield JP, Hunt LP, Stevens MC.

Pediatr Blood Cancer. 2013 Dec;60(12):E157-9. doi: 10.1002/pbc.24689. Epub 2013 Jul 19.

PMID:
23868820
19.

Identifying families' reasons for engaging or not engaging with childhood obesity services: A qualitative study.

Banks J, Cramer H, Sharp DJ, Shield JP, Turner KM.

J Child Health Care. 2014 Jun;18(2):101-10. doi: 10.1177/1367493512473854. Epub 2013 May 31.

PMID:
23728931
20.

High intensity interval running enhances measures of physical fitness but not metabolic measures of cardiovascular disease risk in healthy adolescents.

Buchan DS, Ollis S, Young JD, Cooper SM, Shield JP, Baker JS.

BMC Public Health. 2013 May 24;13:498. doi: 10.1186/1471-2458-13-498.

21.

Cost and effectiveness of treatment options for childhood obesity.

Hollinghurst S, Hunt LP, Banks J, Sharp DJ, Shield JP.

Pediatr Obes. 2014 Feb;9(1):e26-34. doi: 10.1111/j.2047-6310.2013.00150.x. Epub 2013 Mar 18.

PMID:
23505002
22.

Clinical presentation of 6q24 transient neonatal diabetes mellitus (6q24 TNDM) and genotype-phenotype correlation in an international cohort of patients.

Docherty LE, Kabwama S, Lehmann A, Hawke E, Harrison L, Flanagan SE, Ellard S, Hattersley AT, Shield JP, Ennis S, Mackay DJ, Temple IK.

Diabetologia. 2013 Apr;56(4):758-62. doi: 10.1007/s00125-013-2832-1. Epub 2013 Feb 6.

PMID:
23385738
23.

Clinical and molecular characterisation of hyperinsulinaemic hypoglycaemia in infants born small-for-gestational age.

Arya VB, Flanagan SE, Kumaran A, Shield JP, Ellard S, Hussain K, Kapoor RR.

Arch Dis Child Fetal Neonatal Ed. 2013 Jul;98(4):F356-8. doi: 10.1136/archdischild-2012-302880. Epub 2013 Jan 29.

24.

Clinical and molecular characterisation of 300 patients with congenital hyperinsulinism.

Kapoor RR, Flanagan SE, Arya VB, Shield JP, Ellard S, Hussain K.

Eur J Endocrinol. 2013 Mar 15;168(4):557-64. doi: 10.1530/EJE-12-0673. Print 2013 Apr.

25.

Early-onset, coexisting autoimmunity and decreased HLA-mediated susceptibility are the characteristics of diabetes in Down syndrome.

Aitken RJ, Mehers KL, Williams AJ, Brown J, Bingley PJ, Holl RW, Rohrer TR, Schober E, Abdul-Rasoul MM, Shield JP, Gillespie KM.

Diabetes Care. 2013 May;36(5):1181-5. doi: 10.2337/dc12-1712. Epub 2012 Dec 28.

26.

Is labetalol really a culprit in neonatal hypoglycaemia?

Daskas N, Crowne E, Shield JP.

Arch Dis Child Fetal Neonatal Ed. 2013 Mar;98(2):F185. doi: 10.1136/archdischild-2012-303057. Epub 2012 Oct 31. No abstract available.

PMID:
23118200
27.

How does physical activity and fitness influence glycaemic control in young people with Type 1 diabetes?

Cuenca-García M, Jago R, Shield JP, Burren CP.

Diabet Med. 2012 Oct;29(10):e369-76. doi: 10.1111/j.1464-5491.2012.03740.x.

PMID:
22803800
28.

Assessment of childhood obesity in secondary care: OSCA consensus statement.

Viner RM, White B, Barrett T, Candy DC, Gibson P, Gregory JW, Matyka K, Ong K, Roche E, Rudolf MC, Shaikh G, Shield JP, Wales JK.

Arch Dis Child Educ Pract Ed. 2012 Jun;97(3):98-105. doi: 10.1136/edpract-2011-301426.

PMID:
22611124
29.

Evaluating the transferability of a hospital-based childhood obesity clinic to primary care: a randomised controlled trial.

Banks J, Sharp DJ, Hunt LP, Shield JP.

Br J Gen Pract. 2012 Jan;62(594):e6-12. doi: 10.3399/bjgp12X616319.

30.

Is healthy eating for obese children necessarily more costly for families?

Banks J, Williams J, Cumberlidge T, Cimonetti T, Sharp DJ, Shield JP.

Br J Gen Pract. 2012 Jan;62(594):e1-5. doi: 10.3399/bjgp12X616300.

31.

Serum levels of pigment epithelium-derived factor (PEDF) are positively associated with acanthosis nigricans in obese adolescents.

Galhardo J, Hunt LP, Shield JP.

Diabet Med. 2012 Jul;29(7):e117-20. doi: 10.1111/j.1464-5491.2012.03592.x.

PMID:
22288782
32.

The Bristol Online Obesity Screening Tool: experience of using a screening tool for assessing obese children in primary care.

Owen SE, Sharp DJ, Shield JP.

Prim Health Care Res Dev. 2011 Oct;12(4):293-300. doi: 10.1017/S1463423611000132.

PMID:
22284945
33.

Normalizing eating behavior reduces body weight and improves gastrointestinal hormonal secretion in obese adolescents.

Galhardo J, Hunt LP, Lightman SL, Sabin MA, Bergh C, Sodersten P, Shield JP.

J Clin Endocrinol Metab. 2012 Feb;97(2):E193-201. doi: 10.1210/jc.2011-1999. Epub 2011 Dec 7.

PMID:
22162463
34.

Parents' views and experiences of childhood obesity management in primary care: a qualitative study.

Turner KM, Salisbury C, Shield JP.

Fam Pract. 2012 Aug;29(4):476-81. doi: 10.1093/fampra/cmr111. Epub 2011 Nov 24.

PMID:
22117082
35.
36.

3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase.

Sass JO, Walter M, Shield JP, Atherton AM, Garg U, Scott D, Woods CG, Smith LD.

J Inherit Metab Dis. 2012 May;35(3):437-42. doi: 10.1007/s10545-011-9381-x. Epub 2011 Aug 24.

PMID:
21863277
37.

Barriers engaging families and GPs in childhood weight management strategies.

Banks J, Shield JP, Sharp D.

Br J Gen Pract. 2011 Aug;61(589):e492-7. doi: 10.3399/bjgp11X588466.

38.

Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations.

Kapoor RR, Flanagan SE, James CT, McKiernan J, Thomas AM, Harmer SC, Shield JP, Tinker A, Ellard S, Hussain K.

Diabetologia. 2011 Oct;54(10):2575-83. doi: 10.1007/s00125-011-2207-4. Epub 2011 Jun 15.

39.

Blood pressure in children in relation to relative body fat composition and cardio-respiratory fitness.

Hunt LP, Shield JP, Cooper AR, Ness AR, Lawlor DA.

Int J Pediatr Obes. 2011 Aug;6(3-4):275-84. doi: 10.3109/17477166.2011.583655. Epub 2011 Jun 7.

PMID:
21649556
40.

Abnormal liver function in children with metabolic syndrome from a UK-based obesity clinic.

Wei C, Ford A, Hunt L, Crowne EC, Shield JP.

Arch Dis Child. 2011 Nov;96(11):1003-7. doi: 10.1136/adc.2010.190975. Epub 2010 Nov 19.

PMID:
21097793
41.

6q24 transient neonatal diabetes.

Temple IK, Shield JP.

Rev Endocr Metab Disord. 2010 Sep;11(3):199-204. doi: 10.1007/s11154-010-9150-4. Review.

PMID:
20922569
42.

European Medicines Agency withdrawal for sibutramine.

Galhardo J, Davis N, Matthai S, Shield JP.

Arch Dis Child. 2010 Oct;95(10):856. doi: 10.1136/adc.2010.190959. Epub 2010 Jun 23. No abstract available.

PMID:
20573736
43.

Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase.

Zeng L, Biernacka KM, Holly JM, Jarrett C, Morrison AA, Morgan A, Winters ZE, Foulstone EJ, Shield JP, Perks CM.

Endocr Relat Cancer. 2010 May 18;17(2):539-51. doi: 10.1677/ERC-09-0221. Print 2010 Jun.

PMID:
20356977
44.

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations.

Flanagan SE, Kapoor RR, Mali G, Cody D, Murphy N, Schwahn B, Siahanidou T, Banerjee I, Akcay T, Rubio-Cabezas O, Shield JP, Hussain K, Ellard S.

Eur J Endocrinol. 2010 May;162(5):987-92. doi: 10.1530/EJE-09-0861. Epub 2010 Feb 17.

45.

Pancreatic hypoplasia presenting with neonatal diabetes mellitus in association with congenital heart defect and developmental delay.

Balasubramanian M, Shield JP, Acerini CL, Walker J, Ellard S, Marchand M, Polak M, Vaxillaire M, Crolla JA, Bunyan DJ, Mackay DJ, Temple IK.

Am J Med Genet A. 2010 Feb;152A(2):340-6. doi: 10.1002/ajmg.a.33194.

PMID:
20082465
46.

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival.

Rauschenberger K, Schöler K, Sass JO, Sauer S, Djuric Z, Rumig C, Wolf NI, Okun JG, Kölker S, Schwarz H, Fischer C, Grziwa B, Runz H, Nümann A, Shafqat N, Kavanagh KL, Hämmerling G, Wanders RJ, Shield JP, Wendel U, Stern D, Nawroth P, Hoffmann GF, Bartram CR, Arnold B, Bierhaus A, Oppermann U, Steinbeisser H, Zschocke J.

EMBO Mol Med. 2010 Feb;2(2):51-62. doi: 10.1002/emmm.200900055.

47.

Treatment of childhood obesity by retraining eating behaviour: randomised controlled trial.

Ford AL, Bergh C, Södersten P, Sabin MA, Hollinghurst S, Hunt LP, Shield JP.

BMJ. 2009 Jan 5;340:b5388. doi: 10.1136/bmj.b5388.

PMID:
20051465
48.

What reduction in BMI SDS is required in obese adolescents to improve body composition and cardiometabolic health?

Ford AL, Hunt LP, Cooper A, Shield JP.

Arch Dis Child. 2010 Apr;95(4):256-61. doi: 10.1136/adc.2009.165340. Epub 2009 Dec 4.

PMID:
19966092
49.

Practitioners' views on managing childhood obesity in primary care: a qualitative study.

Turner KM, Shield JP, Salisbury C.

Br J Gen Pract. 2009 Nov;59(568):856-62. doi: 10.3399/bjgp09X472269. Epub 2009 Aug 26.

50.

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations.

Kapoor RR, Flanagan SE, Fulton P, Chakrapani A, Chadefaux B, Ben-Omran T, Banerjee I, Shield JP, Ellard S, Hussain K.

Eur J Endocrinol. 2009 Nov;161(5):731-5. doi: 10.1530/EJE-09-0615. Epub 2009 Aug 18.

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