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Items: 28


First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors.

Shitara K, Ueha S, Shichino S, Aoki H, Ogiwara H, Nakatsura T, Suzuki T, Shimomura M, Yoshikawa T, Shoda K, Kitano S, Yamashita M, Nakayama T, Sato A, Kuroda S, Wakabayashi M, Nomura S, Yokochi S, Ito S, Matsushima K, Doi T.

J Immunother Cancer. 2019 Jul 24;7(1):195. doi: 10.1186/s40425-019-0677-y.


In vitro expansion of endogenous human alveolar epithelial type II cells in fibroblast-free spheroid culture.

Shiraishi K, Nakajima T, Shichino S, Deshimaru S, Matsushima K, Ueha S.

Biochem Biophys Res Commun. 2019 Aug 6;515(4):579-585. doi: 10.1016/j.bbrc.2019.05.187. Epub 2019 Jun 6.


Gli signaling pathway modulates fibroblast activation and facilitates scar formation in pulmonary fibrosis.

Tsukui T, Ueha S, Shichino S, Hashimoto S, Nakajima T, Shiraishi K, Kihara M, Kiyonari H, Inagaki Y, Matsushima K.

Biochem Biophys Res Commun. 2019 Jun 30;514(3):684-690. doi: 10.1016/j.bbrc.2019.05.011. Epub 2019 May 8.


Engraftment and proliferation potential of embryonic lung tissue cells in irradiated mice with emphysema.

Shiraishi K, Shichino S, Tsukui T, Hashimoto S, Ueha S, Matsushima K.

Sci Rep. 2019 Mar 6;9(1):3657. doi: 10.1038/s41598-019-40237-x.


TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody Administration.

Aoki H, Ueha S, Shichino S, Ogiwara H, Hashimoto SI, Kakimi K, Ito S, Matsushima K.

Front Immunol. 2019 Jan 24;9:3185. doi: 10.3389/fimmu.2018.03185. eCollection 2018.


Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice.

Chen CY, Ueha S, Ishiwata Y, Yokochi S, Yang, Oppenheim JJ, Ogiwara H, Shichino S, Deshimaru S, Shand FHW, Shibayama S, Matsushima K.

J Immunother Cancer. 2019 Jan 29;7(1):21. doi: 10.1186/s40425-019-0503-6.


Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation.

Shiraishi K, Shichino S, Ueha S, Nakajima T, Hashimoto S, Yamazaki S, Matsushima K.

iScience. 2019 Jan 25;11:318-333. doi: 10.1016/j.isci.2018.12.022. Epub 2018 Dec 26.


Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis.

Shichino S, Ueha S, Hashimoto S, Otsuji M, Abe J, Tsukui T, Deshimaru S, Nakajima T, Kosugi-Kanaya M, Shand FH, Inagaki Y, Shimano H, Matsushima K.

JCI Insight. 2019 Jan 10;4(1). pii: 122163. doi: 10.1172/jci.insight.122163. [Epub ahead of print]


Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-╬▓-associated fibroblast activation in murine pulmonary fibrosis.

Souma K, Shichino S, Hashimoto S, Ueha S, Tsukui T, Nakajima T, Suzuki HI, Shand FHW, Inagaki Y, Nagase T, Matsushima K.

Sci Rep. 2018 Nov 9;8(1):16642. doi: 10.1038/s41598-018-34839-0.


Reduction of Proliferating Olfactory Cells and Low Expression of Extracellular Matrix Genes Are Hallmarks of the Aged Olfactory Mucosa.

Ueha R, Shichino S, Ueha S, Kondo K, Kikuta S, Nishijima H, Matsushima K, Yamasoba T.

Front Aging Neurosci. 2018 Mar 27;10:86. doi: 10.3389/fnagi.2018.00086. eCollection 2018.


Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice.

Kosugi-Kanaya M, Ueha S, Abe J, Shichino S, Shand FHW, Morikawa T, Kurachi M, Shono Y, Sudo N, Yamashita A, Suenaga F, Yokoyama A, Yong W, Imamura M, Teshima T, Matsushima K.

Front Immunol. 2017 Dec 18;8:1842. doi: 10.3389/fimmu.2017.01842. eCollection 2017.


Simian Immunodeficiency Virus Targeting of CXCR3+ CD4+ T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.

Fujino M, Sato H, Okamura T, Uda A, Takeda S, Ahmed N, Shichino S, Shiino T, Saito Y, Watanabe S, Sugimoto C, Kuroda MJ, Ato M, Nagai Y, Izumo S, Matsushima K, Miyazawa M, Ansari AA, Villinger F, Mori K.

J Virol. 2017 Jun 9;91(13). pii: e00439-17. doi: 10.1128/JVI.00439-17. Print 2017 Jul 1.


Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.

Shichino S, Abe J, Ueha S, Otsuji M, Tsukui T, Kosugi-Kanaya M, Shand FH, Hashimoto S, Suzuki HI, Morikawa T, Inagaki Y, Matsushima K.

Am J Pathol. 2015 Nov;185(11):2923-38. doi: 10.1016/j.ajpath.2015.07.013. Epub 2015 Oct 9.


Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis.

Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K.

Am J Pathol. 2015 Nov;185(11):2939-48. doi: 10.1016/j.ajpath.2015.07.022. Epub 2015 Oct 9.


Robust Antitumor Effects of Combined Anti-CD4-Depleting Antibody and Anti-PD-1/PD-L1 Immune Checkpoint Antibody Treatment in Mice.

Ueha S, Yokochi S, Ishiwata Y, Ogiwara H, Chand K, Nakajima T, Hachiga K, Shichino S, Terashima Y, Toda E, Shand FH, Kakimi K, Ito S, Matsushima K.

Cancer Immunol Res. 2015 Jun;3(6):631-40. doi: 10.1158/2326-6066.CIR-14-0190. Epub 2015 Feb 20.


Lymph node stromal cells negatively regulate antigen-specific CD4+ T cell responses.

Abe J, Shichino S, Ueha S, Hashimoto S, Tomura M, Inagaki Y, Stein JV, Matsushima K.

J Immunol. 2014 Aug 15;193(4):1636-44. doi: 10.4049/jimmunol.1302946. Epub 2014 Jul 14.


Tracking of intertissue migration reveals the origins of tumor-infiltrating monocytes.

Shand FH, Ueha S, Otsuji M, Koid SS, Shichino S, Tsukui T, Kosugi-Kanaya M, Abe J, Tomura M, Ziogas J, Matsushima K.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):7771-6. doi: 10.1073/pnas.1402914111. Epub 2014 May 13.


Qualitative rather than quantitative changes are hallmarks of fibroblasts in bleomycin-induced pulmonary fibrosis.

Tsukui T, Ueha S, Abe J, Hashimoto S, Shichino S, Shimaoka T, Shand FH, Arakawa Y, Oshima K, Hattori M, Inagaki Y, Tomura M, Matsushima K.

Am J Pathol. 2013 Sep;183(3):758-73. doi: 10.1016/j.ajpath.2013.06.005. Epub 2013 Jul 22.


Angiodysplasia of the appendix.

Kyokane T, Akita Y, Katayama M, Kitagawa Y, Sato T, Shichino S, Nimura Y.

Am J Gastroenterol. 2001 Jan;96(1):242-4.


Multiple angiomyolipomas of the liver (case report).

Kyokane T, Akita Y, Katayama M, Sato T, Shichino S, Nimura Y.

Hepatogastroenterology. 1995 Sep-Oct;42(5):510-5.


[A case of inflammatory polyp of the gallbladder which was difficult to differentiate from cancer].

Kyokane T, Akita Y, Katayama M, Kitagawa Y, Shichino S, Sato T.

Nihon Shokakibyo Gakkai Zasshi. 1994 May;91(5):1062-6. Japanese. No abstract available.


Cholesterol polyp of the gallbladder showing rapid growth and atypical changes--a case report.

Ukai K, Akita Y, Mizuno S, Ohta A, Ogawa A, Ohshima A, Kyoukane T, Shichino S, Sato T, Nimura Y, et al.

Hepatogastroenterology. 1992 Aug;39(4):371-3. Review.


[Anatomical studies on the biliary tree of the caudate lobe using an endoscopic retrograde cholangiogram].

Hayakawa N, Nimura Y, Kamiya J, Shionoya S, Shichino S, Sato T, Katayama M.

Nihon Geka Gakkai Zasshi. 1987 Jul;88(7):839-44. Japanese.


[A case of bilateral brachial plexus palsy after an operation in Trendelenburg position].

Sato T, Shichino S, Akita Y, Katayama M, Miyata M, Maki A, Kawamura T, Suzuki H, Fukatsu H.

Masui. 1986 Sep;35(9):1408-13. Japanese. No abstract available.


[A case report of a double cancer of the ureter and stomach].

Yamamoto H, Shichino S, Satoh T, Akita Y, Kanai M, Katoh T, Katayama M, Miura Y, Katoh S, Hane A, et al.

Gan No Rinsho. 1985 Feb;31(2):206-11. Japanese.


[Survey of deaths during anesthesia and early postoperative period in recent 20 years].

Sato T, Shichino S, Nagino M, Kato T, Kanai M, Katayama M, Miura Y.

Masui. 1982 Nov;31(11):1281-6. Japanese. No abstract available.


[A study of the effect on liver function of multiple exposures to anesthetics (author's transl)].

Sato T, Shichino S, Isobe Y, Kishimoto H, Akita Y, Kono H, Nagino M.

Masui. 1980 Aug;29(8):804-10. Japanese. No abstract available.


[Postoperative liver function. 2].

Sato T, Kamiya T, Ieda H, Nimura Y, Shichino S.

Masui. 1973 Oct;22(11):1248-54. Japanese. No abstract available.


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