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Items: 1 to 50 of 60

1.

A New Methodology to Create Polymeric Nanocarriers Containing Hydrophilic Low Molecular-Weight Drugs: A Green Strategy Providing a Very High Drug Loading.

Villamizar-Sarmiento MG, Molina-Soto EF, Guerrero J, Shibue T, Nishide H, Moreno-Villoslada I, Oyarzun-Ampuero FA.

Mol Pharm. 2019 Jul 1;16(7):2892-2901. doi: 10.1021/acs.molpharmaceut.9b00097. Epub 2019 Jun 3.

PMID:
31181908
2.

Triboionization: a Novel Ionization Method by Peeling of Cohesive Substances for Mass Spectrometry.

Sugimura N, Watabe Y, Shibue T.

J Am Soc Mass Spectrom. 2019 May 17. doi: 10.1007/s13361-019-02220-8. [Epub ahead of print]

PMID:
31102188
3.

WRN helicase is a synthetic lethal target in microsatellite unstable cancers.

Chan EM, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EA, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka YE, Liu Y, Roper J, Raghavan S, Giannakis M, Tseng YY, Nagel ZD, D'Andrea A, Root DE, Boehm JS, Getz G, Chang S, Golub TR, Tsherniak A, Vazquez F, Bass AJ.

Nature. 2019 Apr;568(7753):551-556. doi: 10.1038/s41586-019-1102-x. Epub 2019 Apr 10.

PMID:
30971823
4.

Long-lived water clusters in hydrophobic solvents investigated by standard NMR techniques.

Oka K, Shibue T, Sugimura N, Watabe Y, Winther-Jensen B, Nishide H.

Sci Rep. 2019 Jan 18;9(1):223. doi: 10.1038/s41598-018-36787-1.

5.

Aggregation Number in Water/n-Hexanol Molecular Clusters Formed in Cyclohexane at Different Water/n-Hexanol/Cyclohexane Compositions Calculated by Titration 1H NMR.

Flores ME, Shibue T, Sugimura N, Nishide H, Moreno-Villoslada I.

J Phys Chem B. 2017 Nov 9;121(44):10285-10291. doi: 10.1021/acs.jpcb.7b08848. Epub 2017 Oct 26.

PMID:
29028169
6.

Nudged elastic band method and density functional theory calculation for finding a local minimum energy pathway of p-benzoquinone and phenol fragmentation in mass spectrometry.

Sugimura N, Igarashi Y, Aoyama R, Shibue T.

Eur J Mass Spectrom (Chichester). 2017 Feb;23(1):40-44. doi: 10.1177/1469066716688412. Epub 2017 Feb 9.

PMID:
28657448
7.

Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library.

Sugimura N, Furuya A, Yatsu T, Igarashi Y, Aoyama R, Izutani C, Yamamoto Y, Shibue T.

Eur J Mass Spectrom (Chichester). 2017 Feb;23(1):4-10. doi: 10.1177/1469066717693851. Epub 2017 Jan 1.

PMID:
28657446
8.

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications.

Shibue T, Weinberg RA.

Nat Rev Clin Oncol. 2017 Oct;14(10):611-629. doi: 10.1038/nrclinonc.2017.44. Epub 2017 Apr 11. Review.

9.

Structural Insights into a Hemoglobin-Albumin Cluster in Aqueous Medium.

Shinohara R, Yamada T, Schade B, Böttcher C, Sato T, Sugimura N, Shibue T, Komatsu T.

J Phys Chem Lett. 2017 Feb 16;8(4):819-824. doi: 10.1021/acs.jpclett.6b02907. Epub 2017 Feb 6.

PMID:
28151688
10.

Water-Induced Phase Transition in Cyclohexane/n-Hexanol/Triton X-100 Mixtures at a Molar Composition of 1/16/74 Studied by NMR.

Flores ME, Martínez F, Olea AF, Shibue T, Sugimura N, Nishide H, Moreno-Villoslada I.

J Phys Chem B. 2017 Feb 2;121(4):876-882. doi: 10.1021/acs.jpcb.6b11752. Epub 2017 Jan 20.

PMID:
28060513
11.

Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency.

De Cock JM, Shibue T, Dongre A, Keckesova Z, Reinhardt F, Weinberg RA.

Cancer Res. 2016 Dec 1;76(23):6778-6784. Epub 2016 Aug 16.

12.

In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase.

Tan CM, Gill CJ, Wu J, Toussaint N, Yin J, Tsuchiya T, Garlisi CG, Kaelin D, Meinke PT, Miesel L, Olsen DB, Lagrutta A, Fukuda H, Kishii R, Takei M, Oohata K, Takeuchi T, Shibue T, Takano H, Nishimura A, Fukuda Y, Singh SB.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4830-9. doi: 10.1128/AAC.00619-16. Print 2016 Aug.

13.

Stability of Water/Poly(ethylene oxide)43-b-poly(ε-caprolactone)14/Cyclohexanone Emulsions Involves Water Exchange between the Core and the Bulk.

Flores ME, Martínez F, Olea AF, Shibue T, Sugimura N, Nishide H, Moreno-Villoslada I.

J Phys Chem B. 2015 Dec 31;119(52):15929-37. doi: 10.1021/acs.jpcb.5b10274. Epub 2015 Dec 17.

PMID:
26637018
14.

Prediction of adducts on positive mode electrospray ionization mass spectrometry: proton/sodium selectivity in methanol solutions.

Sugimura N, Furuya A, Yatsu T, Shibue T.

Eur J Mass Spectrom (Chichester). 2015;21(5):725-31. doi: 10.1255/ejms.1389.

PMID:
26579928
15.

Photochromic Solid Materials Based on Poly(decylviologen) Complexed with Alginate and Poly(sodium 4-styrenesulfonate).

Sanhueza L, Castro J, Urzúa E, Barrientos L, Oyarzun-Ampuero F, Pesenti H, Shibue T, Sugimura N, Tomita W, Nishide H, Moreno-Villoslada I.

J Phys Chem B. 2015 Oct 15;119(41):13208-17. doi: 10.1021/acs.jpcb.5b05963. Epub 2015 Oct 6.

PMID:
26398329
16.

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells.

Ye X, Tam WL, Shibue T, Kaygusuz Y, Reinhardt F, Ng Eaton E, Weinberg RA.

Nature. 2015 Sep 10;525(7568):256-60. doi: 10.1038/nature14897. Epub 2015 Sep 2.

17.

Comparison of the applicability of mass spectrometer ion sources using a polarity- molecular weight scattergram with a 600 sample in-house chemical library.

Sugimura N, Furuya A, Yatsu T, Shibue T.

Eur J Mass Spectrom (Chichester). 2015;21(2):91-6. doi: 10.1255/ejms.1345.

PMID:
26181282
18.

Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6).

Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Meinke PT, Olsen DB, Lagrutta A, Wei C, Liao Y, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Yajima M, Shibue T, Shibata T, Ohata K, Nishimura A, Fukuda Y.

Bioorg Med Chem Lett. 2015 Sep 1;25(17):3636-43. doi: 10.1016/j.bmcl.2015.06.057. Epub 2015 Jun 19.

PMID:
26141771
19.

Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3).

Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Gill C, Black T, Nargund R, Meinke PT, Olsen DB, Lagrutta A, Wei C, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Takeuchi T, Shibue T, Ohata K, Takano H, Ban S, Nishimura A, Fukuda Y.

Bioorg Med Chem Lett. 2015 Jun 15;25(12):2473-8. doi: 10.1016/j.bmcl.2015.04.063. Epub 2015 Apr 28.

PMID:
25978963
20.

Correlating intravital multi-photon microscopy to 3D electron microscopy of invading tumor cells using anatomical reference points.

Karreman MA, Mercier L, Schieber NL, Shibue T, Schwab Y, Goetz JG.

PLoS One. 2014 Dec 5;9(12):e114448. doi: 10.1371/journal.pone.0114448. eCollection 2014.

21.

The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming.

Unternaehrer JJ, Zhao R, Kim K, Cesana M, Powers JT, Ratanasirintrawoot S, Onder T, Shibue T, Weinberg RA, Daley GQ.

Stem Cell Reports. 2014 Nov 11;3(5):691-8. doi: 10.1016/j.stemcr.2014.09.008. Epub 2014 Oct 11.

22.

Stereoselective synthesis of cis-2-fluorocyclopropanecarboxylic acid.

Shibue T, Fukuda Y.

J Org Chem. 2014 Aug 1;79(15):7226-31. doi: 10.1021/jo501219n. Epub 2014 Jul 18.

PMID:
25010939
23.

Topotactic conversion of β-helix-layered silicate into AST-type zeolite through successive interlayer modifications.

Asakura Y, Takayama R, Shibue T, Kuroda K.

Chemistry. 2014 Feb 10;20(7):1893-900. doi: 10.1002/chem.201303368. Epub 2014 Jan 15.

PMID:
24431158
24.

An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonization.

Shibue T, Brooks MW, Weinberg RA.

Cancer Cell. 2013 Oct 14;24(4):481-98. doi: 10.1016/j.ccr.2013.08.012. Epub 2013 Sep 12. Erratum in: Cancer Cell. 2013 Dec 9;24(6):806-8.

25.

The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions.

Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA.

Cancer Discov. 2012 Aug;2(8):706-21. doi: 10.1158/2159-8290.CD-11-0239. Epub 2012 May 18.

26.

Slug and Sox9 cooperatively determine the mammary stem cell state.

Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA.

Cell. 2012 Mar 2;148(5):1015-28. doi: 10.1016/j.cell.2012.02.008.

27.

Practical conversion of chlorosilanes into alkoxysilanes without generating HCl.

Wakabayashi R, Sugiura Y, Shibue T, Kuroda K.

Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10708-11. doi: 10.1002/anie.201104948. Epub 2011 Sep 20. No abstract available.

PMID:
21932229
28.

Metastatic colonization: settlement, adaptation and propagation of tumor cells in a foreign tissue environment.

Shibue T, Weinberg RA.

Semin Cancer Biol. 2011 Apr;21(2):99-106. doi: 10.1016/j.semcancer.2010.12.003. Epub 2010 Dec 9. Review.

PMID:
21145969
29.

Estimation for diameter of superparamagnetic particles in Daphnia resting eggs.

Sakata M, Kawasaki T, Shibue T, Namiki H.

Biophysics (Nagoya-shi). 2010 Dec 7;6:53-57. eCollection 2010.

30.

Synthesis and biological evaluation of tubulysin D analogs related to stereoisomers of tubuvaline.

Shibue T, Okamoto I, Morita N, Morita H, Hirasawa Y, Hosoya T, Tamura O.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):431-4. doi: 10.1016/j.bmcl.2010.10.118. Epub 2010 Oct 30.

PMID:
21106374
31.

Total syntheses of tubulysins.

Shibue T, Hirai T, Okamoto I, Morita N, Masu H, Azumaya I, Tamura O.

Chemistry. 2010 Oct 11;16(38):11678-88. doi: 10.1002/chem.201000963. Epub 2010 Aug 23.

PMID:
20734394
32.

Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs.

Shibue T, Weinberg RA.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10290-5. doi: 10.1073/pnas.0904227106. Epub 2009 Jun 5. Erratum in: Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14734. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):563.

33.

Therapeutic potential of proapoptotic molecule Noxa in the selective elimination of tumor cells.

Suzuki S, Nakasato M, Shibue T, Koshima I, Taniguchi T.

Cancer Sci. 2009 Apr;100(4):759-69. doi: 10.1111/j.1349-7006.2009.01096.x. Epub 2009 Mar 9.

34.

Synthesis and structure-activity relationship studies of highly potent novel oxazolidinone antibacterials.

Komine T, Kojima A, Asahina Y, Saito T, Takano H, Shibue T, Fukuda Y.

J Med Chem. 2008 Oct 23;51(20):6558-62. doi: 10.1021/jm800800c. Epub 2008 Oct 1.

PMID:
18826297
35.

Aromatic-aromatic interaction between 2,3,5-triphenyl-2H-tetrazolium chloride and poly(sodium 4-styrenesulfonate).

Moreno-Villoslada I, González F, Rivera L, Hess S, Rivas BL, Shibue T, Nishide H.

J Phys Chem B. 2007 Jun 7;111(22):6146-50. Epub 2007 May 16.

PMID:
17503806
36.

Magnetic characterization of Daphnia resting eggs.

Sakata M, Kawasaki T, Shibue T, Takada A, Yoshimura H, Namiki H.

Biochem Biophys Res Commun. 2006 Dec 15;351(2):566-70. Epub 2006 Oct 23.

PMID:
17070770
37.

Complex formation between rhodamine B and poly(sodium 4-styrenesulfonate) studied by 1H-NMR.

Moreno-Villoslada I, Gonzalez R, Hess S, Rivas BL, Shibue T, Nishide H.

J Phys Chem B. 2006 Nov 2;110(43):21576-81.

PMID:
17064110
38.

Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways.

Shibue T, Suzuki S, Okamoto H, Yoshida H, Ohba Y, Takaoka A, Taniguchi T.

EMBO J. 2006 Oct 18;25(20):4952-62. Epub 2006 Oct 5.

39.

BH3-only proteins: integrated control point of apoptosis.

Shibue T, Taniguchi T.

Int J Cancer. 2006 Nov 1;119(9):2036-43.

41.
42.

Stability of porphyrin-calix[4]arene complexes analyzed by electrospray ionization mass spectrometry.

Arai S, Ishihara S, Takeoka S, Ohkawa H, Shibue T, Nishide H.

Rapid Commun Mass Spectrom. 2004;18(18):2065-8.

PMID:
15378719
44.

Crystalline calcium phosphate and magnetic mineral content of Daphnia resting eggs.

Kawasaki T, Yoshimura H, Shibue T, Ikeuchi Y, Sakata M, Igarashi K, Takada H, Hoshino K, Kohn K, Namiki H.

Zoolog Sci. 2004 Jan;21(1):63-7.

PMID:
14745105
45.

Integral role of Noxa in p53-mediated apoptotic response.

Shibue T, Takeda K, Oda E, Tanaka H, Murasawa H, Takaoka A, Morishita Y, Akira S, Taniguchi T, Tanaka N.

Genes Dev. 2003 Sep 15;17(18):2233-8. Epub 2003 Sep 2.

46.

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, Kikuchi H, Sasaki S, Imai K, Shibue T, Honda K, Taniguchi T.

Nature. 2003 Jul 31;424(6948):516-23.

PMID:
12872134
47.

TNFR2 position 196 polymorphism in Japanese patients with rheumatoid arthritis: comment on the article by Dieudé et al.

Kyogoku C, Tsuchiya N, Shibue T, Tokunaga K, Matsuta K.

Arthritis Rheum. 2003 Jan;48(1):273-4. No abstract available.

48.

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.

Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N.

Science. 2000 May 12;288(5468):1053-8.

50.

Tumor necrosis factor alpha 5'-flanking region, tumor necrosis factor receptor II, and HLA-DRB1 polymorphisms in Japanese patients with rheumatoid arthritis.

Shibue T, Tsuchiya N, Komata T, Matsushita M, Shiota M, Ohashi J, Wakui M, Matsuta K, Tokunaga K.

Arthritis Rheum. 2000 Apr;43(4):753-7. Erratum in: Arthritis Rheum. 2005 May;52(5):1619.

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