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SNIPERs-Hijacking IAP activity to induce protein degradation.

Naito M, Ohoka N, Shibata N.

Drug Discov Today Technol. 2019 Apr;31:35-42. doi: 10.1016/j.ddtec.2018.12.002. Epub 2019 Jan 14. Review.


Atomic resolution electron microscopy in a magnetic field free environment.

Shibata N, Kohno Y, Nakamura A, Morishita S, Seki T, Kumamoto A, Sawada H, Matsumoto T, Findlay SD, Ikuhara Y.

Nat Commun. 2019 May 24;10(1):2308. doi: 10.1038/s41467-019-10281-2.


p.N345K mutation in TARDBP in a patient with familial amyotrophic lateral sclerosis: An autopsy case.

Takeda T, Iijima M, Shimizu Y, Yoshizawa H, Miyashiro M, Onizuka H, Yamamoto T, Nishiyama A, Suzuki N, Aoki M, Shibata N, Kitagawa K.

Neuropathology. 2019 May 24. doi: 10.1111/neup.12559. [Epub ahead of print]


Direct observation of atomic-scale fracture path within ceramic grain boundary core.

Kondo S, Ishihara A, Tochigi E, Shibata N, Ikuhara Y.

Nat Commun. 2019 May 8;10(1):2112. doi: 10.1038/s41467-019-10183-3.


[Investigation of transition from pediatric to adult health care for patients with special health-care needs for neurological disease dating from childhood].

Mochizuki Y, Takeuchi C, Osako M, Minatogawa M, Shibata N.

Rinsho Shinkeigaku. 2019 May 28;59(5):279-281. doi: 10.5692/ Epub 2019 Apr 26. Japanese.


High contrast STEM imaging for light elements by an annular segmented detector.

Ooe K, Seki T, Ikuhara Y, Shibata N.

Ultramicroscopy. 2019 Jul;202:148-155. doi: 10.1016/j.ultramic.2019.04.011. Epub 2019 Apr 23.


A Case of a Full-Term Infant With Symptomatic Patent Ductus Arteriosus Successfully Closed With Indomethacin Treatment: Consideration of Mechanism for Ductus Arteriosus Closure.

Tanabe J, Nakajima S, Yasuda K, Shibata N, Taketani T, Tanabe K.

CASE (Phila). 2019 Feb 15;3(2):46-50. doi: 10.1016/ eCollection 2019 Apr. No abstract available.


Multimodality findings of coronary stenosis and aneurysm in Takayasu arteritis: a case report.

Shibata N, Taniguchi T, Umemoto N, Shimizu K, Murohara T.

Coron Artery Dis. 2019 Apr 16. doi: 10.1097/MCA.0000000000000749. [Epub ahead of print] No abstract available.


Gas/Liquid-Phase Micro-Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N-Sulfinylimines.

Hirano K, Gondo S, Punna N, Tokunaga E, Shibata N.

ChemistryOpen. 2019 Feb 5;8(4):406-410. doi: 10.1002/open.201800286. eCollection 2019 Apr.


Gas/Liquid-Phase Micro-Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and N-Sulfinylimines.

Hirano K, Gondo S, Punna N, Tokunaga E, Shibata N.

ChemistryOpen. 2019 Mar 12;8(4):402. doi: 10.1002/open.201900070. eCollection 2019 Apr.


Controlling Chaotic Resonance using External Feedback Signals in Neural Systems.

Nobukawa S, Shibata N.

Sci Rep. 2019 Mar 21;9(1):4990. doi: 10.1038/s41598-019-41535-0.


Rapid pleural effusion after discontinuation of lenvatinib in a patient with pleural metastasis from thyroid cancer.

Uchida T, Yamaguchi H, Nagamine K, Yonekawa T, Nakamura E, Shibata N, Kawano F, Asada Y, Nakazato M.

Endocrinol Diabetes Metab Case Rep. 2019 Mar 18;2019. pii: EDM180158. doi: 10.1530/EDM-18-0158. [Epub ahead of print]


Prehospital quick sequential organ failure assessment score to predict in-hospital mortality among patients with trauma.

Miyamoto K, Shibata N, Ogawa A, Nakashima T, Kato S.

Am J Emerg Med. 2019 Mar 8. pii: S0735-6757(19)30156-1. doi: 10.1016/j.ajem.2019.03.007. [Epub ahead of print]


Metabolomics profiles of patients with Wilson disease reveal a distinct metabolic signature.

Sarode GV, Kim K, Kieffer DA, Shibata NM, Litwin T, Czlonkowska A, Medici V.

Metabolomics. 2019 Mar 12;15(3):43. doi: 10.1007/s11306-019-1505-6.


Distinct Roles for Peyer's Patch B Cells for Induction of Antigen-specific IgA Antibody Responses in Mice Administered Oral Recombinant Salmonella.

Hashizume-Takizawa T, Shibata N, Kurashima Y, Kiyono H, Kurita-Ochiai T, Fujihashi K.

Int Immunol. 2019 Mar 14. pii: dxz029. doi: 10.1093/intimm/dxz029. [Epub ahead of print]


Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.

Iwasawa T, Shinomiya T, Ota N, Shibata N, Nakata K, Shiina I, Nagahara Y.

Biol Pharm Bull. 2019;42(3):401-410. doi: 10.1248/bpb.b18-00643.


Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein.

Shibata N, Ohoka N, Hattori T, Naito M.

Chem Pharm Bull (Tokyo). 2019;67(3):165-172. doi: 10.1248/cpb.c18-00703. Review.


Unusual Oxygen Partial Pressure Dependence of Electrical Transport of Single-Crystalline Metal Oxide Nanowires Grown by the Vapor-Liquid-Solid Process.

Anzai H, Takahashi T, Suzuki M, Kanai M, Zhang G, Hosomi T, Seki T, Nagashima K, Shibata N, Yanagida T.

Nano Lett. 2019 Mar 13;19(3):1675-1681. doi: 10.1021/acs.nanolett.8b04668. Epub 2019 Mar 5.


Pd-Catalyzed Decarboxylative Cyclization of Trifluoromethyl Vinyl Benzoxazinanones with Sulfur Ylides: Access to Trifluoromethyl Dihydroquinolines.

Punna N, Harada K, Zhou J, Shibata N.

Org Lett. 2019 Mar 1;21(5):1515-1520. doi: 10.1021/acs.orglett.9b00330. Epub 2019 Feb 21.


Atomic Scale Origin of Enhanced Ionic Conductivity at Crystal Defects.

Feng B, Ishikawa R, Kumamoto A, Shibata N, Ikuhara Y.

Nano Lett. 2019 Mar 13;19(3):2162-2168. doi: 10.1021/acs.nanolett.9b00506. Epub 2019 Feb 27.


The Early Initiation of Extracorporeal Life Support May Improve the Neurological Outcome in Adults with Cardiac Arrest due to Cardiac Events.

Komeyama S, Takagi K, Tsuboi H, Tsuboi S, Morita Y, Yoshida R, Kanzaki Y, Nagai H, Ikai Y, Furui K, Tsuzuki K, Shibata N, Yoshioka N, Yamauchi R, Sugiyama H, Morishima I.

Intern Med. 2019 May 15;58(10):1391-1397. doi: 10.2169/internalmedicine.0864-18. Epub 2019 Feb 1.


High-resolution structure of a Y27W mutant of the Dishevelled2 DIX domain.

Yamanishi K, Sin Y, Terawaki SI, Higuchi Y, Shibata N.

Acta Crystallogr F Struct Biol Commun. 2019 Feb 1;75(Pt 2):116-122. doi: 10.1107/S2053230X18018290. Epub 2019 Jan 23.


Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers.

Mordaunt CE, Kieffer DA, Shibata NM, Członkowska A, Litwin T, Weiss KH, Zhu Y, Bowlus CL, Sarkar S, Cooper S, Wan YY, Ali MR, LaSalle JM, Medici V.

Epigenetics Chromatin. 2019 Feb 1;12(1):10. doi: 10.1186/s13072-019-0255-z.


Asymmetric Electrophilic Difluoromethylthiolation of Indanone-Based β-Keto Esters Using Difluoromethanesulfonyl Hypervalent Iodonium Ylides.

Gondo S, Matsubara O, Chachignon H, Sumii Y, Cahard D, Shibata N.

Molecules. 2019 Jan 9;24(2). pii: E221. doi: 10.3390/molecules24020221.


Metabolic reprogramming in the pathogenesis of glioma: Update.

Masui K, Onizuka H, Cavenee WK, Mischel PS, Shibata N.

Neuropathology. 2019 Feb;39(1):3-13. doi: 10.1111/neup.12535. Epub 2019 Jan 4. Review.


Large angle illumination enabling accurate structure reconstruction from thick samples in scanning transmission electron microscopy.

Brown HG, Ishikawa R, S Anchez-Santolino G, Shibata N, Ikuhara Y, Allen LJ, Findlay SD.

Ultramicroscopy. 2019 Feb;197:112-121. doi: 10.1016/j.ultramic.2018.12.010. Epub 2018 Dec 17.


Structural Changes of the Trinuclear Copper Center in Bilirubin Oxidase upon Reduction.

Tokiwa T, Shoji M, Sladek V, Shibata N, Higuchi Y, Kataoka K, Sakurai T, Shigeta Y, Misaizu F.

Molecules. 2018 Dec 26;24(1). pii: E76. doi: 10.3390/molecules24010076.


Successful endovascular treatment of endoscopically unmanageable hemorrhage from a duodenal ulcer fed by a renal artery: A case report.

Anami S, Minamiguchi H, Shibata N, Koyama T, Sato H, Ikoma A, Nakai M, Yamagami T, Sonomura T.

World J Clin Cases. 2018 Dec 6;6(15):1012-1017. doi: 10.12998/wjcc.v6.i15.1012.


Efficient hydrogen evolution on (CuInS2)x(ZnS)1-x solid solution-based photocathodes under simulated sunlight.

Zhao J, Minegishi T, Kaneko H, Ma G, Zhong M, Nakabayashi M, Hisatomi T, Katayama M, Shibata N, Yamada T, Domen K.

Chem Commun (Camb). 2019 Jan 3;55(4):470-473. doi: 10.1039/c8cc08623k.


Impact of anti-doping education and doping control experience on anti-doping knowledge in Japanese university athletes: a cross-sectional study.

Murofushi Y, Kawata Y, Kamimura A, Hirosawa M, Shibata N.

Subst Abuse Treat Prev Policy. 2018 Dec 5;13(1):44. doi: 10.1186/s13011-018-0178-x.


Polyvinyl alcohol-iodine induced corneal epithelial injury in vivo and its protection by topical rebamipide treatment.

Fukuda M, Shibata S, Shibata N, Fujita N, Miyashita H, Tanimura N, Ishida H, Kubo E, Sasaki H.

PLoS One. 2018 Nov 29;13(11):e0208198. doi: 10.1371/journal.pone.0208198. eCollection 2018.


Surface Protective and Catalytic Layer Consisting of RuO2 and Pt for Stable Production of Methylcyclohexane Using Solar Energy.

Kageshima Y, Minegishi T, Sugisaki S, Goto Y, Kaneko H, Nakabayashi M, Shibata N, Domen K.

ACS Appl Mater Interfaces. 2018 Dec 26;10(51):44396-44402. doi: 10.1021/acsami.8b14814. Epub 2018 Dec 11.


Contrast-Induced Nephropathy and Long-Term Clinical Outcomes Following Percutaneous Coronary Intervention in Patients With Advanced Renal Dysfunction (Estimated Glomerular Filtration Rate <30 ml/min/1.73 m2).

Negishi Y, Tanaka A, Ishii H, Takagi K, Inoue Y, Uemura Y, Umemoto N, Yoshioka N, Morishima I, Asano H, Watarai M, Shibata N, Suzuki S, Murohara T.

Am J Cardiol. 2019 Feb 1;123(3):361-367. doi: 10.1016/j.amjcard.2018.10.038. Epub 2018 Nov 6.


Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers.

Tokunaga E, Yamamoto T, Ito E, Shibata N.

Sci Rep. 2018 Nov 20;8(1):17131. doi: 10.1038/s41598-018-35457-6.


Accurate measurement of electric potentials in biased GaAs compound semiconductors by phase-shifting electron holography.

Anada S, Yamamoto K, Sasaki H, Shibata N, Matsumoto M, Hori Y, Kinugawa K, Imamura A, Hirayama T.

Microscopy (Oxf). 2019 Apr 1;68(2):159-166. doi: 10.1093/jmicro/dfy131.


Identification of Two Mannosyltransferases Contributing to Biosynthesis of the Fungal-type Galactomannan α-Core-Mannan Structure in Aspergillus fumigatus.

Onoue T, Tanaka Y, Hagiwara D, Ekino K, Watanabe A, Ohta K, Kamei K, Shibata N, Goto M, Oka T.

Sci Rep. 2018 Nov 16;8(1):16918. doi: 10.1038/s41598-018-35059-2.


Synthesis of Chiral Nonracemic α-Difluoromethylthio Compounds with Tetrasubstituted Stereogenic Centers via a Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation.

Kondo H, Maeno M, Sasaki K, Guo M, Hashimoto M, Shiro M, Shibata N.

Org Lett. 2018 Nov 16;20(22):7044-7048. doi: 10.1021/acs.orglett.8b02998. Epub 2018 Nov 8.


Different Degradation Mechanisms of Inhibitor of Apoptosis Proteins (IAPs) by the Specific and Nongenetic IAP-Dependent Protein Eraser (SNIPER).

Ohoka N, Ujikawa O, Shimokawa K, Sameshima T, Shibata N, Hattori T, Nara H, Cho N, Naito M.

Chem Pharm Bull (Tokyo). 2019 Mar 1;67(3):203-209. doi: 10.1248/cpb.c18-00567. Epub 2018 Oct 26.


Defluorosilylation of fluoroarenes and fluoroalkanes.

Cui B, Jia S, Tokunaga E, Shibata N.

Nat Commun. 2018 Oct 22;9(1):4393. doi: 10.1038/s41467-018-06830-w.


mTOR Complexes as a Nutrient Sensor for Driving Cancer Progression.

Harachi M, Masui K, Okamura Y, Tsukui R, Mischel PS, Shibata N.

Int J Mol Sci. 2018 Oct 21;19(10). pii: E3267. doi: 10.3390/ijms19103267. Review.


Ultrasonographic and radiological imaging demonstrating an anomalous origin of the left coronary artery causing acute coronary syndrome in an adolescent.

Taniguchi T, Umemoto N, Ishii H, Nakahata K, Shibata N, Mizutani T, Yamada M, Shimizu K, Murohara T.

J Cardiol Cases. 2018 Apr 1;17(4):141-145. doi: 10.1016/j.jccase.2017.12.008. eCollection 2018 Apr.


Development of a deep residual learning algorithm to screen for glaucoma from fundus photography.

Shibata N, Tanito M, Mitsuhashi K, Fujino Y, Matsuura M, Murata H, Asaoka R.

Sci Rep. 2018 Oct 2;8(1):14665. doi: 10.1038/s41598-018-33013-w.


Direct electric field imaging of graphene defects.

Ishikawa R, Findlay SD, Seki T, Sánchez-Santolino G, Kohno Y, Ikuhara Y, Shibata N.

Nat Commun. 2018 Sep 24;9(1):3878. doi: 10.1038/s41467-018-06387-8.


A case of non-alcoholic steatohepatitis complicated with severe acute pancreatitis induced by decreased lipoprotein lipase and hepatic triglyceride lipase activity levels in a young Japanese woman.

Minohara S, Bae SK, Sugiyama S, Shibata N, Gushima T, Motoshita J, Shimoda S, Takagi A, Ikeda Y, Takahashi K.

Clin Case Rep. 2018 Jul 18;6(9):1769-1773. doi: 10.1002/ccr3.1706. eCollection 2018 Sep.


Pharmacological difference between degrader and inhibitor against oncogenic BCR-ABL kinase.

Shibata N, Shimokawa K, Nagai K, Ohoka N, Hattori T, Miyamoto N, Ujikawa O, Sameshima T, Nara H, Cho N, Naito M.

Sci Rep. 2018 Sep 10;8(1):13549. doi: 10.1038/s41598-018-31913-5.


Cytotoxicity analysis of staphylococcal bi-component β-pore forming toxins using the CHO cells expressing human lymphocyte receptor CCR5.

Peng Z, Shibata N, Tada H, Kaneko J.

Biosci Biotechnol Biochem. 2018 Dec;82(12):2094-2097. doi: 10.1080/09168451.2018.1515614. Epub 2018 Sep 5.


Redox Potential-Dependent Formation of an Unusual His-Trp Bond in Bilirubin Oxidase.

Akter M, Tokiwa T, Shoji M, Nishikawa K, Shigeta Y, Sakurai T, Higuchi Y, Kataoka K, Shibata N.

Chemistry. 2018 Dec 5;24(68):18052-18058. doi: 10.1002/chem.201803798. Epub 2018 Nov 15.


Design and synthesis of galactose-conjugated fluorinated and non-fluorinated proline oligomers: towards antifreeze molecules.

Sumii Y, Hibino H, Saidalimu I, Kawahara H, Shibata N.

Chem Commun (Camb). 2018 Aug 28;54(70):9749-9752. doi: 10.1039/c8cc05588b.


Nonbacterial Thrombotic Endocarditis Concomitant with Repeated Systemic Embolization That Received Palliative Care Based on the Antemortem Diagnosis.

Shibata N, Matsumoto K, Kitamura S, Sakashita A, Kizawa Y, Hirata KI.

Intern Med. 2018 Dec 15;57(24):3559-3563. doi: 10.2169/internalmedicine.1381-18. Epub 2018 Aug 10.


Probing the Internal Atomic Charge Density Distributions in Real Space.

Sánchez-Santolino G, Lugg NR, Seki T, Ishikawa R, Findlay SD, Kohno Y, Kanitani Y, Tanaka S, Tomiya S, Ikuhara Y, Shibata N.

ACS Nano. 2018 Sep 25;12(9):8875-8881. doi: 10.1021/acsnano.8b03712. Epub 2018 Aug 3.


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