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Items: 1 to 50 of 738

1.

Synthesis of Unprotected Spirocyclic β-Prolines and β-Homoprolines by Rh-Catalyzed C-H Insertion.

Espinosa M, Noda H, Shibasaki M.

Org Lett. 2019 Oct 3. doi: 10.1021/acs.orglett.9b03198. [Epub ahead of print]

PMID:
31580682
2.

TriQuinoline.

Adachi S, Shibasaki M, Kumagai N.

Nat Commun. 2019 Aug 23;10(1):3820. doi: 10.1038/s41467-019-11818-1.

3.

Direct Catalytic Asymmetric Addition of Acetonitrile to Aldimines.

Saito A, Kumagai N, Shibasaki M.

Org Lett. 2019 Oct 18;21(20):8187-8190. doi: 10.1021/acs.orglett.9b02821. Epub 2019 Aug 14.

PMID:
31411484
4.

Development of Novel δ Opioid Receptor Inverse Agonists without a Basic Nitrogen Atom and Their Antitussive Effects in Mice.

Higashi E, Hirayama S, Nikaido J, Shibasaki M, Kono T, Honjo A, Ikeda H, Kamei J, Fujii H.

ACS Chem Neurosci. 2019 Sep 18;10(9):3939-3945. doi: 10.1021/acschemneuro.9b00368. Epub 2019 Aug 15.

PMID:
31397148
5.

Lewis Base Assisted Lithium Brønsted Base Catalysis: A New Entry for Catalytic Asymmetric Synthesis of β2,2-Amino Acids.

Amemiya F, Noda H, Shibasaki M.

Chem Pharm Bull (Tokyo). 2019 Oct 1;67(10):1046-1049. doi: 10.1248/cpb.c19-00569. Epub 2019 Jul 25.

6.

Effects of whole body skin cooling on human cognitive processing: a study using SEPs and ERPs.

Nakata H, Kobayashi F, Lawley JS, Kakigi R, Shibasaki M.

Am J Physiol Regul Integr Comp Physiol. 2019 Sep 1;317(3):R432-R441. doi: 10.1152/ajpregu.00087.2019. Epub 2019 Jul 10.

PMID:
31290686
7.

Traceless Electrophilic Amination for the Synthesis of Unprotected Cyclic β-Amino Acids.

Yu JS, Espinosa M, Noda H, Shibasaki M.

J Am Chem Soc. 2019 Jul 3;141(26):10530-10537. doi: 10.1021/jacs.9b05476. Epub 2019 Jun 21.

PMID:
31188574
8.

Hyperglycaemia augments lipopolysaccharide-induced reduction in rat and human macrophage phagocytosis via the endoplasmic stress-C/EBP homologous protein pathway.

Iida J, Ishii S, Nakajima Y, Sessler DI, Teramae H, Kageyama K, Maeda S, Anada N, Shibasaki M, Sawa T, Nakayama Y.

Br J Anaesth. 2019 Jul;123(1):51-59. doi: 10.1016/j.bja.2019.03.040. Epub 2019 May 10.

PMID:
31084986
9.

Solvent-Dependent Enantiodivergence in anti-Selective Catalytic Asymmetric Nitroaldol Reactions.

Karasawa T, Saito A, Kumagai N, Shibasaki M.

Org Lett. 2019 May 17;21(10):3581-3583. doi: 10.1021/acs.orglett.9b00982. Epub 2019 Apr 17.

PMID:
30995054
10.

Effects of repetitive exercise and thermal stress on human cognitive processing.

Shibasaki M, Namba M, Kamijo YI, Ito T, Kakigi R, Nakata H.

Physiol Rep. 2019 Feb;7(4):e14003. doi: 10.14814/phy2.14003.

11.

All Non-Carbon B3 NO2 Exotic Heterocycles: Synthesis, Dynamics, and Catalysis.

Opie CR, Noda H, Shibasaki M, Kumagai N.

Chemistry. 2019 Mar 27;25(18):4648-4653. doi: 10.1002/chem.201900715. Epub 2019 Mar 8.

PMID:
30770614
12.

A C4N4 Diaminopyrimidine Fluorophore.

Noda H, Asada Y, Maruyama T, Takizawa N, Noda NN, Shibasaki M, Kumagai N.

Chemistry. 2019 Mar 21;25(17):4299-4304. doi: 10.1002/chem.201900467. Epub 2019 Feb 17.

PMID:
30714234
13.

Phylogenetic relationship of prophages is affected by CRISPR selection in Group A Streptococcus.

Yamada S, Shibasaki M, Murase K, Watanabe T, Aikawa C, Nozawa T, Nakagawa I.

BMC Microbiol. 2019 Jan 28;19(1):24. doi: 10.1186/s12866-019-1393-y.

14.

Direct Catalytic Asymmetric Aldol Reaction of α-Alkoxyamides to α-Fluorinated Ketones.

Pluta R, Kumagai N, Shibasaki M.

Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2459-2463. doi: 10.1002/anie.201814607. Epub 2019 Jan 31.

PMID:
30652398
15.

Neighboring Protonation Unveils Lewis Acidity in the B3NO2 Heterocycle.

Noda H, Asada Y, Shibasaki M, Kumagai N.

J Am Chem Soc. 2019 Jan 30;141(4):1546-1554. doi: 10.1021/jacs.8b10336. Epub 2019 Jan 16.

PMID:
30608671
16.

A fluorogenic C4N4 probe for azide-based labelling.

Noda H, Asada Y, Shibasaki M, Kumagai N.

Org Biomol Chem. 2019 Feb 13;17(7):1813-1816. doi: 10.1039/c8ob02695e.

PMID:
30534778
17.

Achiral Trisubstituted Thioureas as Secondary Ligands to CuI Catalysts: Direct Catalytic Asymmetric Addition of α-Fluoronitriles to Imines.

Balaji PV, Brewitz L, Kumagai N, Shibasaki M.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2644-2648. doi: 10.1002/anie.201812673. Epub 2018 Dec 12.

PMID:
30468281
18.

Differences in serum IL-6 response after 1 °C rise in core body temperature in individuals with spinal cord injury and cervical spinal cord injury during local heat stress.

Hashizaki T, Nishimura Y, Teramura K, Umemoto Y, Shibasaki M, Leicht CA, Kouda K, Tajima F.

Int J Hyperthermia. 2018;35(1):541-547. doi: 10.1080/02656736.2018.1511838. Epub 2018 Oct 10.

PMID:
30303416
19.

[Is Balloon-Occluded Transcatheter Arterial Chemoembolization Effective in Patients with Hepatocellular Carcinoma That Is Unresponsive to Conventional Transcatheter Arterial Chemoembolization ?]

Hatanaka T, Arai H, Shibasaki M, Tojima H, Takizawa D, Toyoda M, Takayama H, Abe T, Sato K, Kakizaki S.

Gan To Kagaku Ryoho. 2018 Sep;45(9):1291-1296. Japanese.

PMID:
30237370
20.

anti-Selective Catalytic Asymmetric Nitroaldol Reaction of α-Keto Esters: Intriguing Solvent Effect, Flow Reaction, and Synthesis of Active Pharmaceutical Ingredients.

Karasawa T, Oriez R, Kumagai N, Shibasaki M.

J Am Chem Soc. 2018 Sep 26;140(38):12290-12295. doi: 10.1021/jacs.8b08236. Epub 2018 Sep 17.

PMID:
30176214
21.

Exploiting β-Amino Acid Enolates in Direct Catalytic Diastereo- and Enantioselective C-C Bond-Forming Reactions.

Yu JS, Noda H, Shibasaki M.

Chemistry. 2018 Oct 22;24(59):15796-15800. doi: 10.1002/chem.201804346. Epub 2018 Oct 8.

PMID:
30152580
22.

Warm-, hot- and pain-related neural activities depending on baseline skin temperatures.

Nakata H, Kakigi R, Shibasaki M.

Eur J Pain. 2018 Nov;22(10):1791-1799. doi: 10.1002/ejp.1275. Epub 2018 Jul 16.

PMID:
29956432
23.

Direct Catalytic Asymmetric 1,6-Conjugate Addition of Amides to p-Quinone Methides.

Sun Z, Sun B, Kumagai N, Shibasaki M.

Org Lett. 2018 May 18;20(10):3070-3073. doi: 10.1021/acs.orglett.8b01109. Epub 2018 May 3.

PMID:
29722988
24.

Direct Catalytic Asymmetric Aldol Reaction of α-Vinyl Acetamide.

Takeuchi T, Kumagai N, Shibasaki M.

J Org Chem. 2018 May 18;83(10):5851-5858. doi: 10.1021/acs.joc.8b00743. Epub 2018 May 2.

PMID:
29683326
25.

Role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in predicting pathological response to preoperative super-selective intra-arterial chemoradiotherapy for advanced squamous cell carcinoma of the mandible.

Shibasaki M, Iwai T, Oguri S, Koizumi T, Hirota M, Mitsudo K, Ozawa Y, Tohnai I.

J Bone Oncol. 2018 Feb 7;11:33-37. doi: 10.1016/j.jbo.2018.02.001. eCollection 2018 Jun.

26.

Anti-influenza virus activity of a salcomine derivative mediated by inhibition of viral RNA synthesis.

Takizawa N, Kimura T, Watanabe T, Shibasaki M.

Arch Virol. 2018 Jun;163(6):1607-1614. doi: 10.1007/s00705-018-3779-9. Epub 2018 Mar 1.

PMID:
29497849
27.

Monotherapy with a novel intervenolin derivative, AS-1934, is an effective treatment for Helicobacter pylori infection.

Ohishi T, Masuda T, Abe H, Hayashi C, Adachi H, Ohba SI, Igarashi M, Watanabe T, Mimuro H, Amalia E, Inaoka DK, Mochizuki K, Kita K, Shibasaki M, Kawada M.

Helicobacter. 2018 Apr;23(2):e12470. doi: 10.1111/hel.12470. Epub 2018 Feb 28.

PMID:
29488678
28.

Down-regulation of ghrelin receptors on dopaminergic neurons in the substantia nigra contributes to Parkinson's disease-like motor dysfunction.

Suda Y, Kuzumaki N, Sone T, Narita M, Tanaka K, Hamada Y, Iwasawa C, Shibasaki M, Maekawa A, Matsuo M, Akamatsu W, Hattori N, Okano H, Narita M.

Mol Brain. 2018 Feb 20;11(1):6. doi: 10.1186/s13041-018-0349-8.

29.

Dynamic cerebral autoregulation during cognitive task: effect of hypoxia.

Ogoh S, Nakata H, Miyamoto T, Bailey DM, Shibasaki M.

J Appl Physiol (1985). 2018 Jun 1;124(6):1413-1419. doi: 10.1152/japplphysiol.00909.2017. Epub 2018 Feb 8.

30.

Effect of ghrelin on the motor deficit caused by the ablation of nigrostriatal dopaminergic cells or the inhibition of striatal dopamine receptors.

Suda Y, Kuzumaki N, Narita M, Hamada Y, Shibasaki M, Tanaka K, Tamura H, Kawamura T, Kondo T, Yamanaka A, Narita M.

Biochem Biophys Res Commun. 2018 Feb 19;496(4):1102-1108. doi: 10.1016/j.bbrc.2018.01.145. Epub 2018 Feb 1.

PMID:
29378186
31.

Catalytic Oligopeptide Synthesis.

Liu Z, Noda H, Shibasaki M, Kumagai N.

Org Lett. 2018 Feb 2;20(3):612-615. doi: 10.1021/acs.orglett.7b03735. Epub 2018 Jan 17.

PMID:
29338248
32.

Direct Catalytic Asymmetric Mannich-Type Reaction en Route to α-Hydroxy-β-amino Acid Derivatives.

Sun B, Pluta R, Kumagai N, Shibasaki M.

Org Lett. 2018 Feb 2;20(3):526-529. doi: 10.1021/acs.orglett.7b03609. Epub 2018 Jan 14.

PMID:
29332389
33.

A comparison of static and dynamic cerebral autoregulation during mild whole-body cold stress in individuals with and without cervical spinal cord injury: a pilot study.

van der Scheer JW, Kamijo YI, Leicht CA, Millar PJ, Shibasaki M, Goosey-Tolfrey VL, Tajima F.

Spinal Cord. 2018 May;56(5):469-477. doi: 10.1038/s41393-017-0021-7. Epub 2018 Jan 12.

PMID:
29330514
34.

Direct Catalytic Asymmetric Aldol Reaction of Thioamide with an α-Vinyl Appendage.

Cui J, Ohtsuki A, Watanabe T, Kumagai N, Shibasaki M.

Chemistry. 2018 Feb 21;24(11):2598-2601. doi: 10.1002/chem.201800020. Epub 2018 Jan 25.

PMID:
29315913
35.

Heterogeneous Heterobimetallic Catalysis Enabling Expeditious Access to CF3-Containing vic-Amino Alcohols.

Karasawa T, Kumagai N, Shibasaki M.

Org Lett. 2018 Jan 5;20(1):308-311. doi: 10.1021/acs.orglett.7b03767. Epub 2017 Dec 26.

PMID:
29278337
36.

Quaternary β2,2 -Amino Acids: Catalytic Asymmetric Synthesis and Incorporation into Peptides by Fmoc-Based Solid-Phase Peptide Synthesis.

Yu JS, Noda H, Shibasaki M.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):818-822. doi: 10.1002/anie.201711143. Epub 2017 Dec 14.

PMID:
29168280
37.

Biological activity of intervenolin analogs with a phenyl substituent.

Abe H, Kawada M, Igarashi M, Ohba SI, Hayashi C, Sakashita C, Watanabe T, Shibasaki M.

J Antibiot (Tokyo). 2017 Oct 11. doi: 10.1038/ja.2017.123. [Epub ahead of print]

PMID:
29018268
38.

Synthetic studies of viridiofungins, broad-spectrum antifungal agents and serine palmitoyl transferase inhibitors.

Kumagai N, Shibasaki M.

J Antibiot (Tokyo). 2017 Sep 27. doi: 10.1038/ja.2017.110. [Epub ahead of print] Review.

PMID:
28951603
39.

Effect of increases in cardiac contractility on cerebral blood flow in humans.

Ogoh S, Moralez G, Washio T, Sarma S, Hieda M, Romero SA, Cramer MN, Shibasaki M, Crandall CG.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1155-H1161. doi: 10.1152/ajpheart.00287.2017. Epub 2017 Sep 15.

40.

A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2.

Iijima M, Kubota Y, Sawa R, Kubota Y, Hatano M, Igarashi M, Kawada M, Momose I, Takekawa M, Shibasaki M.

J Antibiot (Tokyo). 2017 Sep 6. doi: 10.1038/ja.2017.100. [Epub ahead of print]

PMID:
28874847
41.

Determination of 3-hydroxypropylmercapturic acid in urine by three column-switching high-performance liquid chromatography with electrochemical detection using a diamond electrode.

Higashi K, Shibasaki M, Kuni K, Uemura T, Waragai M, Uemura K, Igarashi K, Toida T.

J Chromatogr A. 2017 Sep 29;1517:79-85. doi: 10.1016/j.chroma.2017.08.030. Epub 2017 Aug 26.

PMID:
28851527
42.

Investigation of potential targets of Porphyromonas CRISPRs among the genomes of Porphyromonas species.

Watanabe T, Shibasaki M, Maruyama F, Sekizaki T, Nakagawa I.

PLoS One. 2017 Aug 24;12(8):e0183752. doi: 10.1371/journal.pone.0183752. eCollection 2017.

43.

ATP Depletion Assay Led to the Isolation of New 36-Membered Polyol Macrolides Deplelides A and B from Streptomyces sp. MM581-NF15.

Takeuchi T, Hatano M, Umekita M, Hayashi C, Wada SI, Nagayoshi M, Sawa R, Kubota Y, Kawada M, Igarashi M, Shibasaki M.

Org Lett. 2017 Aug 18;19(16):4207-4210. doi: 10.1021/acs.orglett.7b01807. Epub 2017 Aug 8.

PMID:
28786681
44.

Effects of acute hypoxia on human cognitive processing: a study using ERPs and SEPs.

Nakata H, Miyamoto T, Ogoh S, Kakigi R, Shibasaki M.

J Appl Physiol (1985). 2017 Nov 1;123(5):1246-1255. doi: 10.1152/japplphysiol.00348.2017. Epub 2017 Jul 20.

45.

Catalytic Asymmetric Total Synthesis and Stereochemical Revision of Leucinostatin A: A Modulator of Tumor-Stroma Interaction.

Abe H, Ouchi H, Sakashita C, Kawada M, Watanabe T, Shibasaki M.

Chemistry. 2017 Sep 4;23(49):11792-11796. doi: 10.1002/chem.201703239. Epub 2017 Aug 10.

PMID:
28703358
46.

Photocatalytic α-Acylation of Ethers.

Sun Z, Kumagai N, Shibasaki M.

Org Lett. 2017 Jul 21;19(14):3727-3730. doi: 10.1021/acs.orglett.7b01552. Epub 2017 Jul 11.

PMID:
28696708
47.

Direct Catalytic Asymmetric Aldol Addition of an α-CF3 Amide to Arylglyoxal Hydrates.

Matsuzawa A, Noda H, Kumagai N, Shibasaki M.

J Org Chem. 2017 Aug 4;82(15):8304-8308. doi: 10.1021/acs.joc.7b01381. Epub 2017 Jul 19.

PMID:
28692298
48.

Discovery of 2-hydroxyarbekacin, a new aminoglycoside antibiotic with reduced nephrotoxicity.

Takahashi Y, Umemura E, Kobayashi Y, Murakami S, Nawa T, Morinaka A, Miyake T, Shibasaki M.

J Antibiot (Tokyo). 2018 Feb;71(2):345-347. doi: 10.1038/ja.2017.60. Epub 2017 Jun 28. No abstract available.

PMID:
28655929
49.

α,β-Unsaturated Amides as Dipolarophiles: Catalytic Asymmetric exo-Selective 1,3-Dipolar Cycloaddition with Nitrones.

Zhang M, Kumagai N, Shibasaki M.

Chemistry. 2017 Sep 12;23(51):12450-12455. doi: 10.1002/chem.201702330. Epub 2017 Jul 4.

PMID:
28594065
50.

Direct N-acylation of sulfoximines with carboxylic acids catalyzed by the B3NO2 heterocycle.

Noda H, Asada Y, Shibasaki M, Kumagai N.

Chem Commun (Camb). 2017 Jul 4;53(54):7447-7450. doi: 10.1039/c7cc03386a.

PMID:
28569297

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