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Items: 1 to 50 of 226

1.

Genetic analysis of zebrafish homologs of human FOXQ1, foxq1a and foxq1b, in innate immune cell development and bacterial host response.

Earley AM, Dixon CT, Shiau CE.

PLoS One. 2018 Mar 13;13(3):e0194207. doi: 10.1371/journal.pone.0194207. eCollection 2018.

2.

Lymphocyte-Variant Hypereosinophilic Syndrome With Eosinophilic Myocarditis Treated With Steroids and Pegylated Interferon Alfa-2a.

Cheung CC, Constantine M, Ahmadi A, Shiau C, Chen LYC.

Am J Med Sci. 2018 Feb;355(2):201-202. doi: 10.1016/j.amjms.2017.03.030. Epub 2017 Apr 6. No abstract available.

PMID:
29406050
3.

Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells.

Liu HL, Kao TH, Shiau CY, Chen BH.

J Food Drug Anal. 2018 Jan;26(1):31-40. doi: 10.1016/j.jfda.2016.11.022. Epub 2017 Feb 15.

4.

Drug Repurposing Screening Identifies Tioconazole as an ATG4 Inhibitor that Suppresses Autophagy and Sensitizes Cancer Cells to Chemotherapy.

Liu PF, Tsai KL, Hsu CJ, Tsai WL, Cheng JS, Chang HW, Shiau CW, Goan YG, Tseng HH, Wu CH, Reed JC, Yang LW, Shu CW.

Theranostics. 2018 Jan 1;8(3):830-845. doi: 10.7150/thno.22012. eCollection 2018.

5.

Design and Synthesis of Malonamide Derivatives as Antibiotics against Methicillin-Resistant Staphylococcus aureus.

Su JC, Huang YT, Chen CS, Chiu HC, Shiau CW.

Molecules. 2017 Dec 22;23(1). pii: E27. doi: 10.3390/molecules23010027.

6.

Eosinophilic Myocarditis.

Cheung CC, Constantine M, Ahmadi A, Shiau C, Chen LYC.

Am J Med Sci. 2017 Nov;354(5):486-492. doi: 10.1016/j.amjms.2017.04.002. Epub 2017 Apr 6. Review.

PMID:
29173361
7.

Corrigendum to "Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity" [Eur. J. Med. Chem. 55 (2012) 220-227].

Chen KF, Tai WT, Hsu CY, Huang JW, Liu CY, Chen PJ, Kim I, Shiau CW.

Eur J Med Chem. 2018 Jan 1;143:2015. doi: 10.1016/j.ejmech.2017.10.053. Epub 2017 Nov 4. No abstract available.

PMID:
29113744
8.

Targeting SHP-1-STAT3 signaling: A promising therapeutic approach for the treatment of cholangiocarcinoma.

Hu MH, Chen LJ, Chen YL, Tsai MS, Shiau CW, Chao TI, Liu CY, Kao JH, Chen KF.

Oncotarget. 2017 May 10;8(39):65077-65089. doi: 10.18632/oncotarget.17779. eCollection 2017 Sep 12.

9.

The tyrosine kinase inhibitor nintedanib activates SHP-1 and induces apoptosis in triple-negative breast cancer cells.

Liu CY, Huang TT, Chu PY, Huang CT, Lee CH, Wang WL, Lau KY, Tsai WC, Chao TI, Su JC, Chen MH, Shiau CW, Tseng LM, Chen KF.

Exp Mol Med. 2017 Aug 11;49(8):e366. doi: 10.1038/emm.2017.114.

10.

Case Report: Diagnosis of a Rare Plaque-Like Dermal Fibroma Successfully Treated With Mohs Surgery.

Gill P, Arlette J, Shiau CJ, Abi Daoud MS.

J Cutan Med Surg. 2018 Jan/Feb;22(1):89-93. doi: 10.1177/1203475417722733. Epub 2017 Jul 27.

PMID:
28750558
11.

SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma.

Fan LC, Shiau CW, Tai WT, Hung MH, Chu PY, Hsieh FS, Lin H, Yu HC, Chen KF.

Oncogene. 2017 Oct 12;36(41):5768-5769. doi: 10.1038/onc.2017.251. Epub 2017 Jul 17.

PMID:
28714962
12.

The pattern of failure and predictors of locoregional control in lateralized buccogingival cancer after postoperative radiation therapy.

Lai TY, Hu YW, Liu YM, Chen YW, Shiau CY, Chu PY, Tai SK, Lo WL, Wu CH, Wang LW.

J Chin Med Assoc. 2017 Sep;80(9):569-574. doi: 10.1016/j.jcma.2017.06.002. Epub 2017 Jul 4.

13.

Gamma Knife surgery for clival epidural-osseous dural arteriovenous fistulas.

Lee CC, Chen CJ, Chen SC, Yang HC, Lin CJ, Wu CC, Chung WY, Guo WY, Hung-Chi Pan D, Shiau CY, Wu HM.

J Neurosurg. 2018 May;128(5):1364-1371. doi: 10.3171/2017.1.JNS161346. Epub 2017 Jun 16.

PMID:
28621628
14.

Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy.

Huang TT, Su JC, Liu CY, Shiau CW, Chen KF.

Int J Mol Sci. 2017 Jun 8;18(6). pii: E1234. doi: 10.3390/ijms18061234. Review.

15.

Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells.

Liu CY, Chen KF, Chao TI, Chu PY, Huang CT, Huang TT, Yang HP, Wang WL, Lee CH, Lau KY, Tsai WC, Su JC, Wu CY, Chen MH, Shiau CW, Tseng LM.

J Mol Med (Berl). 2017 Sep;95(9):965-975. doi: 10.1007/s00109-017-1549-x. Epub 2017 Jun 4.

PMID:
28578456
16.

Suppression of LPS-induced inflammatory responses by the hydroxyl groups of dexamethasone.

Chuang TY, Cheng AJ, Chen IT, Lan TY, Huang IH, Shiau CW, Hsu CL, Liu YW, Chang ZF, Tseng PH, Kuo JC.

Oncotarget. 2017 Jul 25;8(30):49735-49748. doi: 10.18632/oncotarget.17683.

17.

Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis.

Su TH, Shiau CW, Jao P, Yang NJ, Tai WT, Liu CJ, Tseng TC, Yang HC, Liu CH, Huang KW, Hu TC, Huang YJ, Wu YM, Chen LJ, Chen PJ, Chen DS, Chen KF, Kao JH.

Sci Rep. 2017 May 11;7(1):1728. doi: 10.1038/s41598-017-01572-z.

18.

Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6-independent manner.

Hsieh FS, Chen YL, Hung MH, Chu PY, Tsai MH, Chen LJ, Hsiao YJ, Shih CT, Chang MJ, Chao TI, Shiau CW, Chen KF.

Mol Oncol. 2017 Aug;11(8):1035-1049. doi: 10.1002/1878-0261.12072. Epub 2017 May 15.

19.

Corrigendum: Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.

Teng HW, Hung MH, Chen LJ, Chang MJ, Hsieh FS, Tsai MH, Huang JW, Lin CL, Tseng HW, Kuo ZK, Jiang JK, Yang SH, Shiau CW, Chen KF.

Sci Rep. 2017 Apr 10;7:45612. doi: 10.1038/srep45612. No abstract available.

20.

Carfilzomib induces leukaemia cell apoptosis via inhibiting ELK1/KIAA1524 (Elk-1/CIP2A) and activating PP2A not related to proteasome inhibition.

Liu CY, Hsieh FS, Chu PY, Tsai WC, Huang CT, Yu YB, Huang TT, Ko PS, Hung MH, Wang WL, Shiau CW, Chen KF.

Br J Haematol. 2017 Jun;177(5):726-740. doi: 10.1111/bjh.14620. Epub 2017 Mar 24.

PMID:
28340282
21.

Erratum to: Corrigendum to "Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma".

Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.

J Hepatol. 2017 Jun;66(6):1334-1335. doi: 10.1016/j.jhep.2017.02.021. Epub 2017 Mar 13. No abstract available.

PMID:
28302383
22.

Correction: Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells.

Liu CY, Hu MH, Hsu CJ, Huang CT, Wang DS, Tsai WC, Chen YT, Lee CH, Chu PY, Hsu CC, Chen MH, Shiau CW, Tseng LM, Chen KF.

Oncotarget. 2017 Feb 7;8(6):10760. doi: 10.18632/oncotarget.15112. No abstract available.

23.

Sorafenib analogue SC-60 induces apoptosis through the SHP-1/STAT3 pathway and enhances docetaxel cytotoxicity in triple-negative breast cancer cells.

Liu CY, Su JC, Huang TT, Chu PY, Huang CT, Wang WL, Lee CH, Lau KY, Tsai WC, Yang HP, Shiau CW, Tseng LM, Chen KF.

Mol Oncol. 2017 Mar;11(3):266-279. doi: 10.1002/1878-0261.12033. Epub 2017 Feb 7.

24.

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.

Liu CY, Tseng LM, Su JC, Chang KC, Chu PY, Tai WT, Shiau CW, Chen KF.

Breast Cancer Res. 2017 Jan 11;19(1):5. doi: 10.1186/s13058-017-0800-2. No abstract available.

25.

Corrigendum to "Signal transducer and activator of transcription 3 is a major kinase-independent target of sorafenib in hepatocellular carcinoma".

Tai WT, Cheng AL, Shiau CW, Huang HP, Huang JW, Chen PJ, Chen KF.

J Hepatol. 2017 Mar;66(3):666-668. doi: 10.1016/j.jhep.2016.12.007. Epub 2017 Jan 6. No abstract available.

PMID:
28069352
26.

EGFR-independent Elk1/CIP2A signalling mediates apoptotic effect of an erlotinib derivative TD52 in triple-negative breast cancer cells.

Liu CY, Huang TT, Huang CT, Hu MH, Wang DS, Wang WL, Tsai WC, Lee CH, Lau KY, Yang HP, Chen MH, Shiau CW, Tseng LM, Chen KF.

Eur J Cancer. 2017 Feb;72:112-123. doi: 10.1016/j.ejca.2016.11.012. Epub 2016 Dec 24.

PMID:
28027514
27.

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI.

Ali AA, Hsu FT, Hsieh CL, Shiau CY, Chiang CH, Wei ZH, Chen CY, Huang HS.

Sci Rep. 2016 Nov 11;6:36650. doi: 10.1038/srep36650.

28.

Desorption of isopropyl alcohol from adsorbent with non-thermal plasma.

Shiau CH, Pan KL, Yu SJ, Yan SY, Chang MB.

Environ Technol. 2017 Sep;38(18):2314-2323. doi: 10.1080/09593330.2016.1259354. Epub 2016 Nov 24.

PMID:
27830998
29.

Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma.

Teng HW, Hung MH, Chen LJ, Chang MJ, Hsieh FS, Tsai MH, Huang JW, Lin CL, Tseng HW, Kuo ZK, Jiang JK, Yang SH, Shiau CW, Chen KF.

Sci Rep. 2016 Oct 18;6:35308. doi: 10.1038/srep35308.

30.

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer.

Fan LC, Teng HW, Shiau CW, Tai WT, Hung MH, Yang SH, Jiang JK, Chen KF.

Oncotarget. 2016 Sep 27;7(39):64136-64147. doi: 10.18632/oncotarget.11636.

31.

Genome-wide analysis of HIF-2α chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions.

Lee MC, Huang HJ, Chang TH, Huang HC, Hsieh SY, Chen YS, Chou WY, Chiang CH, Lai CH, Shiau CY.

Sci Rep. 2016 Jul 4;6:29311. doi: 10.1038/srep29311.

32.

Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis.

Su JC, Mar AC, Wu SH, Tai WT, Chu PY, Wu CY, Tseng LM, Lee TC, Chen KF, Liu CY, Chiu HC, Shiau CW.

Sci Rep. 2016 Jul 1;6:28888. doi: 10.1038/srep28888.

33.

Urolithin A suppresses the proliferation of endometrial cancer cells by mediating estrogen receptor-α-dependent gene expression.

Zhang W, Chen JH, Aguilera-Barrantes I, Shiau CW, Sheng X, Wang LS, Stoner GD, Huang YW.

Mol Nutr Food Res. 2016 Nov;60(11):2387-2395. doi: 10.1002/mnfr.201600048. Epub 2016 Jul 25.

34.

Outcomes of 50 Patients With Ewing Sarcoma Family of Tumors Treated at a Single Institution in Taiwan.

Lee CY, Yen CC, Yen HJ, Shiau CY, Chao TC, Wu PK, Chen CF, Chen PC, Wu HT, Chiou HJ, Chen CC, Hung GY, Chen WM.

Medicine (Baltimore). 2016 May;95(22):e3830. doi: 10.1097/MD.0000000000003830.

35.

Novel Anthra[1,2-c][1,2,5]Thiadiazole-6,11-Diones as Promising Anticancer Lead Compounds: Biological Evaluation, Characterization & Molecular Targets Determination.

Ali AA, Lee YR, Chen TC, Chen CL, Lee CC, Shiau CY, Chiang CH, Huang HS.

PLoS One. 2016 Apr 21;11(4):e0154278. doi: 10.1371/journal.pone.0154278. eCollection 2016.

36.

Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.

Mukherjee N, Lu Y, Almeida A, Lambert K, Shiau CW, Su JC, Luo Y, Fujita M, Robinson WA, Robinson SE, Norris DA, Shellman YG.

Oncotarget. 2017 Jul 18;8(29):46801-46817. doi: 10.18632/oncotarget.8695.

37.

Dovitinib Acts As a Novel Radiosensitizer in Hepatocellular Carcinoma by Targeting SHP-1/STAT3 Signaling.

Huang CY, Tai WT, Wu SY, Shih CT, Chen MH, Tsai MH, Kuo CW, Shiau CW, Hung MH, Chen KF.

Int J Radiat Oncol Biol Phys. 2016 Jun 1;95(2):761-71. doi: 10.1016/j.ijrobp.2016.01.016. Epub 2016 Jan 20.

PMID:
26960749
38.

SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma.

Tai WT, Hung MH, Chu PY, Chen YL, Chen LJ, Tsai MH, Chen MH, Shiau CW, Boo YP, Chen KF.

Oncotarget. 2016 Apr 19;7(16):22193-205. doi: 10.18632/oncotarget.7923.

39.

Clinical impact of mutation fraction in epidermal growth factor receptor mutation positive NSCLC patients.

Martin P, Shiau CJ, Pasic M, Tsao M, Kamel-Reid S, Lin S, Tudor R, Cheng S, Higgins B, Burkes R, Ng M, Arif S, Ellis PM, Hubay S, Kuruvilla S, Laurie SA, Li J, Hwang D, Lau A, Shepherd FA, Le LW, Leighl NB.

Br J Cancer. 2016 Mar 15;114(6):616-22. doi: 10.1038/bjc.2016.22. Epub 2016 Feb 18.

40.

Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential.

Hung MH, Chen YL, Chu PY, Shih CT, Yu HC, Tai WT, Shiau CW, Chen KF.

Oncogene. 2016 Sep 15;35(37):4891-902. doi: 10.1038/onc.2016.21. Epub 2016 Feb 15.

PMID:
26876205
41.

Protein tyrosine phosphatase 1B dephosphorylates PITX1 and regulates p120RasGAP in hepatocellular carcinoma.

Tai WT, Chen YL, Chu PY, Chen LJ, Hung MH, Shiau CW, Huang JW, Tsai MH, Chen KF.

Hepatology. 2016 May;63(5):1528-43. doi: 10.1002/hep.28478. Epub 2016 Mar 2. Erratum in: Hepatology. 2017 Jun;65(6):2135-2136.

PMID:
26840794
42.

Lapatinib inhibits CIP2A/PP2A/p-Akt signaling and induces apoptosis in triple negative breast cancer cells.

Liu CY, Hu MH, Hsu CJ, Huang CT, Wang DS, Tsai WC, Chen YT, Lee CH, Chu PY, Hsu CC, Chen MH, Shiau CW, Tseng LM, Chen KF.

Oncotarget. 2016 Feb 23;7(8):9135-49. doi: 10.18632/oncotarget.7035. Erratum in: Oncotarget. 2017 Feb 7;8(6):10760.

43.

A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy.

Chao TI, Tai WT, Hung MH, Tsai MH, Chen MH, Chang MJ, Shiau CW, Chen KF.

Cancer Lett. 2016 Feb 28;371(2):205-13. doi: 10.1016/j.canlet.2015.11.039. Epub 2015 Dec 8.

PMID:
26679051
44.

Lymphocytic panniculitis: an algorithmic approach to lymphocytes in subcutaneous tissue.

Shiau CJ, Abi Daoud MS, Wong SM, Crawford RI.

J Clin Pathol. 2015 Dec;68(12):954-62. doi: 10.1136/jclinpath-2014-202849. Review.

PMID:
26602413
45.

SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A.

Hung MH, Wang CY, Chen YL, Chu PY, Hsiao YJ, Tai WT, Chao TT, Yu HC, Shiau CW, Chen KF.

Oncotarget. 2016 Jan 5;7(1):638-55. doi: 10.18632/oncotarget.6313.

46.

In vitro and in vivo activity of a novel sorafenib derivative SC5005 against MRSA.

Chang HC, Huang YT, Chen CS, Chen YW, Huang YT, Su JC, Teng LJ, Shiau CW, Chiu HC.

J Antimicrob Chemother. 2016 Feb;71(2):449-59. doi: 10.1093/jac/dkv367. Epub 2015 Nov 8.

PMID:
26553845
47.

Gamma Knife Radiosurgery for Atypical and Anaplastic Meningiomas.

Wang WH, Lee CC, Yang HC, Liu KD, Wu HM, Shiau CY, Guo WY, Pan DH, Chung WY, Chen MT.

World Neurosurg. 2016 Mar;87:557-64. doi: 10.1016/j.wneu.2015.10.021. Epub 2015 Oct 17.

PMID:
26485417
48.

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer.

Fan LC, Teng HW, Shiau CW, Tai WT, Hung MH, Yang SH, Jiang JK, Chen KF.

Neoplasia. 2015 Sep;17(9):687-696. doi: 10.1016/j.neo.2015.08.007.

49.

Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes.

Lu J, Trnka MJ, Roh SH, Robinson PJ, Shiau C, Fujimori DG, Chiu W, Burlingame AL, Guan S.

J Am Soc Mass Spectrom. 2015 Dec;26(12):2141-51. doi: 10.1007/s13361-015-1235-6. Epub 2015 Sep 1.

50.

Sorafenib Action in Hepatitis B Virus X-Activated Oncogenic Androgen Pathway in Liver through SHP-1.

Wang SH, Yeh SH, Shiau CW, Chen KF, Lin WH, Tsai TF, Teng YC, Chen DS, Chen PJ.

J Natl Cancer Inst. 2015 Jul 23;107(10). pii: djv190. doi: 10.1093/jnci/djv190. Print 2015 Oct.

PMID:
26206949

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