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Items: 46


Stage I HPV-positive oropharyngeal cancer: Should all patients receive similar treatments?

Yoshida EJ, Luu M, Mallen-St Clair J, Mita AC, Scher KS, Lu DJ, Nguyen AT, Shiao SL, Ho AS, Zumsteg ZS.

Cancer. 2019 Sep 19. doi: 10.1002/cncr.32501. [Epub ahead of print]


Natural killer cell activity and prostate cancer risk in veteran men undergoing prostate biopsy.

Vidal AC, Howard LE, Wiggins E, De Hoedt AM, Shiao SL, Knott S, Taioli E, Fowke JH, Freedland SJ.

Cancer Epidemiol. 2019 Oct;62:101578. doi: 10.1016/j.canep.2019.101578. Epub 2019 Aug 1.


Quantitative lymph node burden as a 'very-high-risk' factor identifying head and neck cancer patients benefiting from postoperative chemoradiation.

Zumsteg ZS, Luu M, Kim S, Tighiouart M, Mita A, Scher KS, Lu DJ, Shiao SL, Mallen-St Clair J, Ho AS.

Ann Oncol. 2019 Jun 5. pii: mdz172. doi: 10.1093/annonc/mdz172. [Epub ahead of print] No abstract available.


Immunogenomic Analysis of Exceptional Responder to ALT-803 (IL-15 Analogue) in BCG Unresponsive Nonmuscle Invasive Bladder Cancer: A Case Series and Review of the Literature.

Huang J, Shiao SL, Furuya H, Rosser CJ.

J Immunother. 2019 Nov/Dec;42(9):354-358. doi: 10.1097/CJI.0000000000000269.


Survival Impact of Adjuvant Therapy in Salivary Gland Cancers following Resection and Neck Dissection.

Aro K, Ho AS, Luu M, Kim S, Tighiouart M, Yoshida EJ, Mallen-St Clair J, Shiao SL, Leivo I, Zumsteg ZS.

Otolaryngol Head Neck Surg. 2019 Jun;160(6):1048-1057. doi: 10.1177/0194599819827851. Epub 2019 Feb 5.


Targeting Innate Immunity to Enhance the Efficacy of Radiation Therapy.

Dar TB, Henson RM, Shiao SL.

Front Immunol. 2019 Jan 14;9:3077. doi: 10.3389/fimmu.2018.03077. eCollection 2018. Review.


A phase 1 study of veliparib, a PARP-1/2 inhibitor, with gemcitabine and radiotherapy in locally advanced pancreatic cancer.

Tuli R, Shiao SL, Nissen N, Tighiouart M, Kim S, Osipov A, Bryant M, Ristow L, Placencio-Hickok V, Hoffman D, Rokhsar S, Scher K, Klempner SJ, Noe P, Davis MJ, Wachsman A, Lo S, Jamil L, Sandler H, Piantadosi S, Hendifar A.

EBioMedicine. 2019 Feb;40:375-381. doi: 10.1016/j.ebiom.2018.12.060. Epub 2019 Jan 8.


Spatial Mapping of Myeloid Cells and Macrophages by Multiplexed Tissue Staining.

Saylor J, Ma Z, Goodridge HS, Huang F, Cress AE, Pandol SJ, Shiao SL, Vidal AC, Wu L, Nickols NG, Gertych A, Knudsen BS.

Front Immunol. 2018 Dec 14;9:2925. doi: 10.3389/fimmu.2018.02925. eCollection 2018.


Quantitative lymph node burden as a 'very-high-risk' factor identifying head and neck cancer patients benefiting from postoperative chemoradiation.

Zumsteg ZS, Luu M, Kim S, Tighiouart M, Mita A, Scher KS, Lu DP, Shiao SL, Mallen-St Clair J, Ho AS.

Ann Oncol. 2019 Jan 1;30(1):76-84. doi: 10.1093/annonc/mdy490.


Human papillomavirus-associated oropharyngeal cancer among patients aged 70 and older: Dramatically increased prevalence and clinical implications.

Lu DJ, Luu M, Mita A, Scher K, Shiao SL, Yoshida EP, Sittig MP, Mallen-St Clair J, Ho AS, Zumsteg ZS.

Eur J Cancer. 2018 Nov;103:195-204. doi: 10.1016/j.ejca.2018.08.015. Epub 2018 Sep 27.


Prometastatic Molecular Profiles in Breast Tumors From Socially Isolated Women.

Bower JE, Shiao SL, Sullivan P, Lamkin DM, Atienza R, Mercado F, Arevalo J, Asher A, Ganz PA, Cole SW.

JNCI Cancer Spectr. 2018 Jul;2(3):pky029. doi: 10.1093/jncics/pky029. Epub 2018 Jul 19.


Development of a novel salivary gland cancer lymph node staging system.

Aro K, Ho AS, Luu M, Kim S, Tighiouart M, Clair JM, Yoshida EJ, Shiao SL, Leivo I, Zumsteg ZS.

Cancer. 2018 Aug 1;124(15):3171-3180. doi: 10.1002/cncr.31535. Epub 2018 May 9.


Postoperative chemoradiotherapy in patients with head and neck cancer aged 70 or older with positive margins or extranodal extension and the influence of nodal classification.

Yoshida EJ, Luu M, David JM, Kim S, Mita A, Scher K, Shiao SL, Tighiouart M, Ho AS, Zumsteg ZS.

Head Neck. 2018 Jun;40(6):1228-1236. doi: 10.1002/hed.25100. Epub 2018 Feb 8.


Incorporating Radiation Oncology into Immunotherapy: proceedings from the ASTRO-SITC-NCI immunotherapy workshop.

Marciscano AE, Walker JM, McGee HM, Kim MM, Kunos CA, Monjazeb AM, Shiao SL, Tran PT, Ahmed MM.

J Immunother Cancer. 2018 Jan 29;6(1):6. doi: 10.1186/s40425-018-0317-y.


Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer.

Ho AS, Kim S, Tighiouart M, Gudino C, Mita A, Scher KS, Laury A, Prasad R, Shiao SL, Ali N, Patio C, Mallen-St Clair J, Van Eyk JE, Zumsteg ZS.

JAMA Oncol. 2018 Jul 1;4(7):985-989. doi: 10.1001/jamaoncol.2017.3852.


The role of macrophage phenotype in regulating the response to radiation therapy.

Shi X, Shiao SL.

Transl Res. 2018 Jan;191:64-80. doi: 10.1016/j.trsl.2017.11.002. Epub 2017 Nov 20. Review.


Facility Volume and Survival in Nasopharyngeal Carcinoma.

Yoshida EJ, Luu M, David JM, Kim S, Mita A, Scher K, Shiao SL, Tighiouart M, Lee NY, Ho AS, Zumsteg ZS.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):408-417. doi: 10.1016/j.ijrobp.2017.09.038. Epub 2017 Sep 28.


Predictors of survival in head and neck mucosal melanoma.

Schmidt MQ, David J, Yoshida EJ, Scher K, Mita A, Shiao SL, Ho AS, Zumsteg ZS.

Oral Oncol. 2017 Oct;73:36-42. doi: 10.1016/j.oraloncology.2017.08.002. Epub 2017 Aug 10.


Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate.

Ma Z, Shiao SL, Yoshida EJ, Swartwood S, Huang F, Doche ME, Chung AP, Knudsen BS, Gertych A.

Diagn Pathol. 2017 Sep 18;12(1):69. doi: 10.1186/s13000-017-0658-8.


Metastatic Lymph Node Burden and Survival in Oral Cavity Cancer.

Ho AS, Kim S, Tighiouart M, Gudino C, Mita A, Scher KS, Laury A, Prasad R, Shiao SL, Van Eyk JE, Zumsteg ZS.

J Clin Oncol. 2017 Nov 1;35(31):3601-3609. doi: 10.1200/JCO.2016.71.1176. Epub 2017 Sep 7.


Combined high-intensity local treatment and systemic therapy in metastatic head and neck squamous cell carcinoma: An analysis of the National Cancer Data Base.

Zumsteg ZS, Luu M, Yoshida EJ, Kim S, Tighiouart M, David JM, Shiao SL, Mita AC, Scher KS, Sherman EJ, Lee NY, Ho AS.

Cancer. 2017 Dec 1;123(23):4583-4593. doi: 10.1002/cncr.30933. Epub 2017 Aug 17.


Treatment at high-volume facilities and academic centers is independently associated with improved survival in patients with locally advanced head and neck cancer.

David JM, Ho AS, Luu M, Yoshida EJ, Kim S, Mita AC, Scher KS, Shiao SL, Tighiouart M, Zumsteg ZS.

Cancer. 2017 Oct 15;123(20):3933-3942. doi: 10.1002/cncr.30843. Epub 2017 Jun 22.


Impact of concomitant chemoradiation on survival for patients with T1-2N1 head and neck cancer.

Zumsteg ZS, Kim S, David JM, Yoshida EJ, Tighiouart M, Shiao SL, Scher K, Mita A, Sherman EJ, Lee NY, Ho AS.

Cancer. 2017 May 1;123(9):1555-1565. doi: 10.1002/cncr.30508. Epub 2016 Dec 21.


The toxicity and efficacy of concomitant chemoradiotherapy in patients aged 70 years and older with oropharyngeal carcinoma in the intensity-modulated radiotherapy era.

Zumsteg ZS, Lok BH, Ho AS, Drill E, Zhang Z, Riaz N, Shiao SL, Ma J, McBride SM, Tsai CJ, Baxi SS, Sherman EJ, Lee NY.

Cancer. 2017 Apr 15;123(8):1345-1353. doi: 10.1002/cncr.30495. Epub 2016 Dec 16.


Incidence of Oropharyngeal Cancer Among Elderly Patients in the United States.

Zumsteg ZS, Cook-Wiens G, Yoshida E, Shiao SL, Lee NY, Mita A, Jeon C, Goodman MT, Ho AS.

JAMA Oncol. 2016 Dec 1;2(12):1617-1623. doi: 10.1001/jamaoncol.2016.1804.


Impact of Afirma gene expression classifier on cytopathology diagnosis and rate of thyroidectomy.

Sacks WL, Bose S, Zumsteg ZS, Wong R, Shiao SL, Braunstein GD, Ho AS.

Cancer Cytopathol. 2016 Oct;124(10):722-728. doi: 10.1002/cncy.21749. Epub 2016 Jun 27.


Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies.

Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ.

Clin Cancer Res. 2016 Sep 1;22(17):4328-40. doi: 10.1158/1078-0432.CCR-15-3026. Epub 2016 Mar 15.


Regulation of prostate cancer progression by the tumor microenvironment.

Shiao SL, Chu GC, Chung LW.

Cancer Lett. 2016 Sep 28;380(1):340-8. doi: 10.1016/j.canlet.2015.12.022. Epub 2016 Jan 28. Review.


Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations.

Zumsteg ZS, Morse N, Krigsfeld G, Gupta G, Higginson DS, Lee NY, Morris L, Ganly I, Shiao SL, Powell SN, Chung CH, Scaltriti M, Baselga J.

Clin Cancer Res. 2016 Apr 15;22(8):2009-19. doi: 10.1158/1078-0432.CCR-15-2245. Epub 2015 Nov 20.


Breast Cancer Survivorship and Cardiovascular Disease: Emerging Approaches in Cardio-Oncology.

Xie Y, Collins WJ, Audeh MW, Shiao SL, Gottlieb RA, Goodman MT, Merz CN, Mehta PK.

Curr Treat Options Cardiovasc Med. 2015 Dec;17(12):60. doi: 10.1007/s11936-015-0421-y.


Nuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell death.

Pham K, Pal R, Qu Y, Liu X, Yu H, Shiao SL, Wang X, O'Brian Smith E, Cui X, Rodney GG, Cheng N.

Free Radic Biol Med. 2015 Aug;85:197-206. doi: 10.1016/j.freeradbiomed.2015.05.003. Epub 2015 May 11.


Impact of the immune system and immunotherapy in colorectal cancer.

Markman JL, Shiao SL.

J Gastrointest Oncol. 2015 Apr;6(2):208-23. doi: 10.3978/j.issn.2078-6891.2014.077. Review.


TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy.

Shiao SL, Ruffell B, DeNardo DG, Faddegon BA, Park CC, Coussens LM.

Cancer Immunol Res. 2015 May;3(5):518-25. doi: 10.1158/2326-6066.CIR-14-0232. Epub 2015 Feb 25.


Immune microenvironments in solid tumors: new targets for therapy.

Shiao SL, Ganesan AP, Rugo HS, Coussens LM.

Genes Dev. 2011 Dec 15;25(24):2559-72. doi: 10.1101/gad.169029.111. Review.


Temporal compartmental dosing effects for robotic prostate stereotactic body radiotherapy.

Shiao SL, Sahgal A, Hu W, Jabbari S, Chuang C, Descovich M, Hsu IC, Gottschalk AR, Roach M 3rd, Ma L.

Phys Med Biol. 2011 Dec 21;56(24):7767-75. doi: 10.1088/0031-9155/56/24/006. Epub 2011 Nov 22.


Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy.

DeNardo DG, Brennan DJ, Rexhepaj E, Ruffell B, Shiao SL, Madden SF, Gallagher WM, Wadhwani N, Keil SD, Junaid SA, Rugo HS, Hwang ES, Jirström K, West BL, Coussens LM.

Cancer Discov. 2011 Jun;1(1):54-67. doi: 10.1158/2159-8274.CD-10-0028. Epub 2011 Jun 1.


The tumor-immune microenvironment and response to radiation therapy.

Shiao SL, Coussens LM.

J Mammary Gland Biol Neoplasia. 2010 Dec;15(4):411-21. doi: 10.1007/s10911-010-9194-9. Epub 2010 Dec 16. Review.


Human effector memory CD4+ T cells directly recognize allogeneic endothelial cells in vitro and in vivo.

Shiao SL, Kirkiles-Smith NC, Shepherd BR, McNiff JM, Carr EJ, Pober JS.

J Immunol. 2007 Oct 1;179(7):4397-404.


TCR signaling antagonizes rapid IP-10-mediated transendothelial migration of effector memory CD4+ T cells.

Manes TD, Shiao SL, Dengler TJ, Pober JS.

J Immunol. 2007 Mar 1;178(5):3237-43.


Immunomodulatory properties of FK734, a humanized anti-CD28 monoclonal antibody with agonistic and antagonistic activities.

Shiao SL, McNiff JM, Masunaga T, Tamura K, Kubo K, Pober JS.

Transplantation. 2007 Feb 15;83(3):304-13.


A dosimetric evaluation of conventional helmet field irradiation versus two-field intensity-modulated radiotherapy technique.

Yu JB, Shiao SL, Knisely JP.

Int J Radiat Oncol Biol Phys. 2007 Jun 1;68(2):621-31. Epub 2007 Feb 2.


Memory T cells and their costimulators in human allograft injury.

Shiao SL, McNiff JM, Pober JS.

J Immunol. 2005 Oct 15;175(8):4886-96.


T cell-mediated vascular dysfunction of human allografts results from IFN-gamma dysregulation of NO synthase.

Koh KP, Wang Y, Yi T, Shiao SL, Lorber MI, Sessa WC, Tellides G, Pober JS.

J Clin Invest. 2004 Sep;114(6):846-56.


T lymphocyte-endothelial cell interactions.

Choi J, Enis DR, Koh KP, Shiao SL, Pober JS.

Annu Rev Immunol. 2004;22:683-709. Review.


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