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Development of Decellularized Cornea by Organic acid Treatment for Corneal Regeneration.

Lin H, Wang T, Li T, Chang Y, Sheu MT, Huang YY, Liu DZ.

Tissue Eng Part A. 2018 Sep 22. doi: 10.1089/ten.TEA.2018.0162. [Epub ahead of print]


Intrathecal Injection of Dual Zipper Kinase shRNA Alleviating the Neuropathic Pain in a Chronic Constrictive Nerve Injury Model.

Sheu ML, Chiang CY, Su HL, Chen CJ, Sheehan J, Pan HC.

Int J Mol Sci. 2018 Aug 16;19(8). pii: E2421. doi: 10.3390/ijms19082421.


Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury.

Uen Y, Wang JW, Wang C, Jhang Y, Chung JY, Tseng T, Sheu M, Lee S.

Oncotarget. 2018 Jun 15;9(46):28165-28175. doi: 10.18632/oncotarget.25589. eCollection 2018 Jun 15.


Outcome of partially irradiated recurrent nonfunctioning pituitary macroadenoma by gamma knife radiosurgery.

Shen CC, You WC, Sun MH, Lee SD, Tsou HK, Chen YJ, Sheu ML, Sheehan J, Pan HC.

J Neurooncol. 2018 Sep;139(3):767-775. doi: 10.1007/s11060-018-2925-2. Epub 2018 Jun 13.


Late administration of high-frequency electrical stimulation increases nerve regeneration without aggravating neuropathic pain in a nerve crush injury.

Su HL, Chiang CY, Lu ZH, Cheng FC, Chen CJ, Sheu ML, Sheehan J, Pan HC.

BMC Neurosci. 2018 Jun 25;19(1):37. doi: 10.1186/s12868-018-0437-9.


Complex Hydrogels Composed of Chitosan with Ring-opened Polyvinyl Pyrrolidone as a Gastroretentive Drug Dosage Form to Enhance the Bioavailability of Bisphosphonates.

Su CY, Ho HO, Chen YC, Yu YT, Liu DZ, Chao FC, Sheu MT.

Sci Rep. 2018 May 25;8(1):8092. doi: 10.1038/s41598-018-26432-2.


Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors.

Su CY, Chen M, Chen LC, Ho YS, Ho HO, Lin SY, Chuang KH, Sheu MT.

Drug Deliv. 2018 Nov;25(1):1066-1079. doi: 10.1080/10717544.2018.1466936.


Down-Regulated Expression of Magnesium Transporter Genes Following a High Magnesium Diet Attenuates Sciatic Nerve Crush Injury.

Chen YJ, Cheng FC, Chen CJ, Su HL, Sheu ML, Sheehan J, Pan HC.

Neurosurgery. 2018 Apr 17. doi: 10.1093/neuros/nyy120. [Epub ahead of print]


Suppression of Cell Growth, Migration and Drug Resistance by Ethanolic Extract of Antrodia cinnamomea in Human Lung Cancer A549 Cells and C57BL/6J Allograft Tumor Model.

Wu CH, Liu FC, Pan CH, Lai MT, Lan SJ, Wu CH, Sheu MJ.

Int J Mol Sci. 2018 Mar 9;19(3). pii: E791. doi: 10.3390/ijms19030791.


Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer.

Chang CE, Hsieh CM, Chen LC, Su CY, Liu DZ, Jhan HJ, Ho HO, Sheu MT.

Drug Deliv. 2018 Nov;25(1):632-643. doi: 10.1080/10717544.2018.1440444.


Association between socioeconomic status and cerebral palsy.

Tseng SH, Lee JY, Chou YL, Sheu ML, Lee YW.

PLoS One. 2018 Jan 24;13(1):e0191724. doi: 10.1371/journal.pone.0191724. eCollection 2018.


Analyzing the effectiveness of teaching and factors in clinical decision-making.

Hsieh MC, Lee MS, Chen TY, Tsai TC, Pai YF, Sheu MM.

Ci Ji Yi Xue Za Zhi. 2017 Oct-Dec;29(4):223-227. doi: 10.4103/tcmj.tcmj_34_17.


Suppressive activities and mechanisms of ugonin J on vascular smooth muscle cells and balloon angioplasty-induced neointimal hyperplasia.

Pan CH, Li PC, Chien YC, Yeh WT, Liaw CC, Sheu MJ, Wu CH.

Phytother Res. 2018 Feb;32(2):312-320. doi: 10.1002/ptr.5979. Epub 2017 Dec 18.


Botulinum toxin type A for the treatment of localized recalcitrant chronic pruritus.

Boozalis E, Sheu M, Selph J, Kwatra SG.

J Am Acad Dermatol. 2018 Jan;78(1):192-194. doi: 10.1016/j.jaad.2017.08.001. Review. No abstract available.


Development and characterization of docetaxel-loaded lecithin-stabilized micellar drug delivery system (LsbMDDs) for improving the therapeutic efficacy and reducing systemic toxicity.

Su CY, Liu JJ, Ho YS, Huang YY, Chang VH, Liu DZ, Chen LC, Ho HO, Sheu MT.

Eur J Pharm Biopharm. 2018 Feb;123:9-19. doi: 10.1016/j.ejpb.2017.11.006. Epub 2017 Nov 14.


Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells.

Liao HF, Pan CH, Chou PY, Chen YF, Wu TS, Sheu MJ, Wu CH.

PLoS One. 2017 Sep 25;12(9):e0185021. doi: 10.1371/journal.pone.0185021. eCollection 2017.


High Immunoreactivity of DUOX2 Is Associated With Poor Response to Preoperative Chemoradiation Therapy and Worse Prognosis in Rectal Cancers.

Lin SC, Chang IW, Hsieh PL, Lin CY, Sun DP, Sheu MJ, Yang CC, Lin LC, He HL, Tian YF.

J Cancer. 2017 Aug 23;8(14):2756-2764. doi: 10.7150/jca.19545. eCollection 2017.


Physical and Pharmacokinetic Characterizations of trans-Resveratrol (t-Rev) Encapsulated with Self-Assembling Lecithin-based Mixed Polymeric Micelles (saLMPMs).

Li TP, Wong WP, Chen LC, Su CY, Chen LG, Liu DZ, Ho HO, Sheu MT.

Sci Rep. 2017 Sep 6;7(1):10674. doi: 10.1038/s41598-017-11320-y.


Outcome of hearing preservation related to tumor morphologic analysis in acoustic neuromas treated by gamma knife radiosurgery.

Pan SY, Liu SA, Sun MH, Tsou HK, Lee SD, Chen YJ, Sheehan J, Sheu ML, Pan HC.

Radiat Oncol. 2017 Aug 15;12(1):134. doi: 10.1186/s13014-017-0875-z.


Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia.

Lee DJ, Kessel E, Lehto T, Liu X, Yoshinaga N, Padari K, Chen YC, Kempter S, Uchida S, Rädler JO, Pooga M, Sheu MT, Kataoka K, Wagner E.

Bioconjug Chem. 2017 Sep 20;28(9):2393-2409. doi: 10.1021/acs.bioconjchem.7b00383. Epub 2017 Aug 24.


TPL2 (Therapeutic Targeting Tumor Progression Locus-2)/ATF4 (Activating Transcription Factor-4)/SDF1α (Chemokine Stromal Cell-Derived Factor-α) Axis Suppresses Diabetic Retinopathy.

Lai DW, Lin KH, Sheu WH, Lee MR, Chen CY, Lee WJ, Hung YW, Shen CC, Chung TJ, Liu SH, Sheu ML.

Circ Res. 2017 Sep 1;121(6):e37-e52. doi: 10.1161/CIRCRESAHA.117.311066. Epub 2017 Jul 19.


Overexpression of Transcobalamin 1 is an Independent Negative Prognosticator in Rectal Cancers Receiving Concurrent Chemoradiotherapy.

Lee YY, Wei YC, Tian YF, Sun DP, Sheu MJ, Yang CC, Lin LC, Lin CY, Hsing CH, Li WS, Li CF, Hsieh PL, Lin CY.

J Cancer. 2017 May 12;8(8):1330-1337. doi: 10.7150/jca.18274. eCollection 2017.


High Expression of Aldolase B Confers a Poor Prognosis for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy.

Tian YF, Hsieh PL, Lin CY, Sun DP, Sheu MJ, Yang CC, Lin LC, He HL, Solórzano J, Li CF, Chang IW.

J Cancer. 2017 Apr 9;8(7):1197-1204. doi: 10.7150/jca.18197. eCollection 2017.


High Expression of EphA4 Predicted Lesser Degree of Tumor Regression after Neoadjuvant Chemoradiotherapy in Rectal Cancer.

Lin CY, Lee YE, Tian YF, Sun DP, Sheu MJ, Lin CY, Li CF, Lee SW, Lin LC, Chang IW, Wang CT, He HL.

J Cancer. 2017 Apr 9;8(6):1089-1096. doi: 10.7150/jca.17471. eCollection 2017.


Prevention of Axonal Degeneration by Perineurium Injection of Mitochondria in a Sciatic Nerve Crush Injury Model.

Kuo CC, Su HL, Chang TL, Chiang CY, Sheu ML, Cheng FC, Chen CJ, Sheehan J, Pan HC.

Neurosurgery. 2017 Mar 1;80(3):475-488. doi: 10.1093/neuros/nyw090.


Corrigendum: Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin.

Chen LC, Chen YC, Su CY, Wong WP, Sheu MT, Ho HO.

Sci Rep. 2017 Mar 22;7:44967. doi: 10.1038/srep44967. No abstract available.


Tamoxifen use and acute pancreatitis: A population-based cohort study.

Hsu FG, Hsieh YW, Sheu MJ, Lin CC, Lin CL, Hsu CY, Lee CY, Chang MY, Chang KH.

PLoS One. 2017 Mar 14;12(3):e0173089. doi: 10.1371/journal.pone.0173089. eCollection 2017.


Effects of ADAMTS14 genetic polymorphism and cigarette smoking on the clinicopathologic development of hepatocellular carcinoma.

Sheu MJ, Hsieh MJ, Chou YE, Wang PH, Yeh CB, Yang SF, Lee HL, Liu YF.

PLoS One. 2017 Feb 23;12(2):e0172506. doi: 10.1371/journal.pone.0172506. eCollection 2017.


The Root Extract of Gentiana macrophylla Pall. Alleviates B19-NS1-Exacerbated Liver Injuries in NZB/W F1 Mice.

Sheu MJ, Chiu CC, Yang DJ, Hsu TC, Tzang BS.

J Med Food. 2017 Jan;20(1):56-64. doi: 10.1089/jmf.2016.3817. Epub 2017 Jan 6.


Ochratoxin A induces ER stress and apoptosis in mesangial cells via a NADPH oxidase-derived reactive oxygen species-mediated calpain activation pathway.

Sheu ML, Shen CC, Chen YS, Chiang CK.

Oncotarget. 2017 Mar 21;8(12):19376-19388. doi: 10.18632/oncotarget.14270.


Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin.

Chen LC, Chen YC, Su CY, Wong WP, Sheu MT, Ho HO.

Sci Rep. 2016 Nov 16;6:37122. doi: 10.1038/srep37122. Erratum in: Sci Rep. 2017 Mar 22;7:44967.


Ophthalmologic abnormalities among students with cognitive impairment in eastern Taiwan: The special group with undetected visual impairment.

Tsao WS, Hsieh HP, Chuang YT, Sheu MM.

J Formos Med Assoc. 2017 May;116(5):345-350. doi: 10.1016/j.jfma.2016.06.013. Epub 2016 Oct 11.


Glutamate Decarboxylase 1 Overexpression as a Poor Prognostic Factor in Patients with Nasopharyngeal Carcinoma.

Lee YY, Chao TB, Sheu MJ, Tian YF, Chen TJ, Lee SW, He HL, Chang IW, Hsing CH, Lin CY, Li CF.

J Cancer. 2016 Jul 27;7(12):1716-1723. eCollection 2016.


Knowledge-based iterative model reconstruction technique in computed tomography of lumbar spine lowers radiation dose and improves tissue differentiation for patients with lower back pain.

Yang CH, Wu TH, Lin CJ, Chiou YY, Chen YC, Sheu MH, Guo WY, Chiu CF.

Eur J Radiol. 2016 Oct;85(10):1757-1764. doi: 10.1016/j.ejrad.2016.07.015. Epub 2016 Jul 20.


Involvement of Endoplasmic Reticulum Stress, Autophagy, and Apoptosis in Advanced Glycation End Products-Induced Glomerular Mesangial Cell Injury.

Chiang CK, Wang CC, Lu TF, Huang KH, Sheu ML, Liu SH, Hung KY.

Sci Rep. 2016 Sep 26;6:34167. doi: 10.1038/srep34167.


The prevalence and risk factors of visual impairment among the elderly in Eastern Taiwan.

Wang WL, Chen N, Sheu MM, Wang JH, Hsu WL, Hu YJ.

Kaohsiung J Med Sci. 2016 Sep;32(9):475-81. doi: 10.1016/j.kjms.2016.07.009. Epub 2016 Aug 31.


Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population-Based Case-Control Study in Taiwan.

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW.

J Clin Pharmacol. 2017 Mar;57(3):376-381. doi: 10.1002/jcph.815. Epub 2016 Sep 22.


Feasibility of Human Amniotic Fluid Derived Stem Cells in Alleviation of Neuropathic Pain in Chronic Constrictive Injury Nerve Model.

Chiang CY, Liu SA, Sheu ML, Chen FC, Chen CJ, Su HL, Pan HC.

PLoS One. 2016 Jul 21;11(7):e0159482. doi: 10.1371/journal.pone.0159482. eCollection 2016.


Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas.

Kim JE, Patel MA, Mangraviti A, Kim ES, Theodros D, Velarde E, Liu A, Sankey EW, Tam A, Xu H, Mathios D, Jackson CM, Harris-Bookman S, Garzon-Muvdi T, Sheu M, Martin AM, Tyler BM, Tran PT, Ye X, Olivi A, Taube JM, Burger PC, Drake CG, Brem H, Pardoll DM, Lim M.

Clin Cancer Res. 2017 Jan 1;23(1):124-136. doi: 10.1158/1078-0432.CCR-15-1535. Epub 2016 Jun 29.


Overexpression of the PSAT1 Gene in Nasopharyngeal Carcinoma Is an Indicator of Poor Prognosis.

Liao KM, Chao TB, Tian YF, Lin CY, Lee SW, Chuang HY, Chan TC, Chen TJ, Hsing CH, Sheu MJ, Li CF.

J Cancer. 2016 May 25;7(9):1088-94. doi: 10.7150/jca.15258. eCollection 2016.


Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo.

Chung YL, Pan CH, Wang CC, Hsu KC, Sheu MJ, Chen HF, Wu CH.

J Nat Prod. 2016 Jun 24;79(6):1635-44. doi: 10.1021/acs.jnatprod.6b00217. Epub 2016 May 26.


Green Tea Catechin Prevents Hypoxia/Reperfusion-Evoked Oxidative Stress-Regulated Autophagy-Activated Apoptosis and Cell Death in Microglial Cells.

Chen CM, Wu CT, Yang TH, Chang YA, Sheu ML, Liu SH.

J Agric Food Chem. 2016 May 25;64(20):4078-85. doi: 10.1021/acs.jafc.6b01513. Epub 2016 May 10.


Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study.

Chen LC, Chen YC, Su CY, Hong CS, Ho HO, Sheu MT.

Int J Nanomedicine. 2016 Apr 15;11:1557-66. doi: 10.2147/IJN.S103681. eCollection 2016.


Improving the Stability of Astaxanthin by Microencapsulation in Calcium Alginate Beads.

Lin SF, Chen YC, Chen RN, Chen LC, Ho HO, Tsung YH, Sheu MT, Liu DZ.

PLoS One. 2016 Apr 19;11(4):e0153685. doi: 10.1371/journal.pone.0153685. eCollection 2016.


The pathological role of advanced glycation end products-downregulated heat shock protein 60 in islet β-cell hypertrophy and dysfunction.

Guan SS, Sheu ML, Yang RS, Chan DC, Wu CT, Yang TH, Chiang CK, Liu SH.

Oncotarget. 2016 Apr 26;7(17):23072-87. doi: 10.18632/oncotarget.8604.

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