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Phase III, randomised, double-blind, multicentre study to evaluate the efficacy and safety of vonoprazan compared with lansoprazole in Asian patients with erosive oesophagitis.

Xiao Y, Zhang S, Dai N, Fei G, Goh KL, Chun HJ, Sheu BS, Chong CF, Funao N, Zhou W, Chen M.

Gut. 2019 Aug 13. pii: gutjnl-2019-318365. doi: 10.1136/gutjnl-2019-318365. [Epub ahead of print]


Increasing antimicrobial resistance to clarithromycin and metronidazole in pediatric Helicobacter pylori infection in southern Taiwan: A comparison between two decades.

Lu HH, Lai FP, Lo HY, Sheu BS, Yang YJ.

Helicobacter. 2019 Jul 11:e12633. doi: 10.1111/hel.12633. [Epub ahead of print]


The recurrent bleeding risk of a Forrest IIc lesion at the second-look endoscopy can be indicated by high Rockall scores ≥ 6.

Yang EH, Wu CT, Kuo HY, Chen WY, Sheu BS, Cheng HC.

Surg Endosc. 2019 Jun 20. doi: 10.1007/s00464-019-06919-3. [Epub ahead of print]


Spasmolytic polypeptide-expressing metaplasia associated with higher expressions of miR-21, 155, and 223 can be regressed by Helicobacter pylori eradication in the gastric cancer familial relatives.

Kuo HY, Chang WL, Yeh YC, Cheng HC, Tsai YC, Wu CT, Lin SH, Yang HB, Lu CC, Sheu BS.

Helicobacter. 2019 Jun;24(3):e12578. doi: 10.1111/hel.12578. Epub 2019 Apr 16.


Lead Time Bias May Contribute to the Shorter Life Expectancy in Post-colonoscopy Colorectal Cancer.

Chen WY, Cheng HC, Cheng WC, Wang JD, Sheu BS.

Dig Dis Sci. 2019 Sep;64(9):2622-2630. doi: 10.1007/s10620-019-05566-x. Epub 2019 Mar 5.


Improved hemostasis with plasma kinetic bipolar sealing device in the vaginal steps of laparoscopic-assisted vaginal hysterectomy.

Tu YA, Chang WC, Wu CJ, Sheu BC.

Taiwan J Obstet Gynecol. 2019 Jan;58(1):64-67. doi: 10.1016/j.tjog.2018.11.012.


H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer.

Yeh YC, Kuo HY, Chang WL, Yang HB, Lu CC, Cheng HC, Wu MS, Sheu BS.

J Biomed Sci. 2019 Jan 5;26(1):4. doi: 10.1186/s12929-019-0498-9.


Helicobacter pylori eradication improves glycemic control in type 2 diabetes patients with asymptomatic active Helicobacter pylori infection.

Cheng KP, Yang YJ, Hung HC, Lin CH, Wu CT, Hung MH, Sheu BS, Ou HY.

J Diabetes Investig. 2019 Jul;10(4):1092-1101. doi: 10.1111/jdi.12991. Epub 2019 Jan 22.


The impacts of H. pylori virulence factors on the development of gastroduodenal diseases.

Chang WL, Yeh YC, Sheu BS.

J Biomed Sci. 2018 Sep 11;25(1):68. doi: 10.1186/s12929-018-0466-9. Review.


The implementation of the consensus on the management of Helicobacter pylori and barriers to consensus.

Cheng HC, Liou JM, Luo JC, Chiu CT, Wu MS, Lee YC, Wu CY, Wu DC, Hsu PI, Chang CC, Chang WL, Lin JT, Sheu BS.

Helicobacter. 2018 Oct;23(5):e12533. doi: 10.1111/hel.12533. Epub 2018 Aug 29.


Nutrition therapy in esophageal cancer-Consensus statement of the Gastroenterological Society of Taiwan.

Chen MJ, Wu IC, Chen YJ, Wang TE, Chang YF, Yang CL, Huang WC, Chang WK, Sheu BS, Wu MS, Lin JT, Chu CH.

Dis Esophagus. 2018 Aug 1;31(8). doi: 10.1093/dote/doy016. Review.


Short tandem repeat analysis for confirmation of uterine non-gestational choriocarcinoma in a postmenopausal Taiwanese woman.

Wu CJ, Hwa HL, Chang WC, Hsu HC, Wu MZ, Sheu BC.

Medicine (Baltimore). 2018 Feb;97(8):e9899. doi: 10.1097/MD.0000000000009899.


Reply to "Hypoalbuminemia is a predictor of mortality and rebleeding in peptic ulcer bleeding under proton pump inhibitor use: Methodological issues".

Cheng HC, Sheu BS.

J Formos Med Assoc. 2018 Mar;117(3):252-253. doi: 10.1016/j.jfma.2017.11.007. Epub 2017 Nov 26. No abstract available.


Male non-insulin users with type 2 diabetes mellitus are predisposed to gastric corpus-predominant inflammation after H. pylori infection.

Yang YJ, Wu CT, Ou HY, Lin CH, Cheng HC, Chang WL, Chen WY, Yang HB, Lu CC, Sheu BS.

J Biomed Sci. 2017 Oct 30;24(1):82. doi: 10.1186/s12929-017-0389-x.


Laparoendoscopic single-site myomectomy using conventional laparoscopic instruments and glove port technique: Four years experience in 109 cases.

Chen SY, Sheu BC, Huang SC, Chang WC.

Taiwan J Obstet Gynecol. 2017 Aug;56(4):467-471. doi: 10.1016/j.tjog.2016.07.016.


Hypoalbuminemia is a predictor of mortality and rebleeding in peptic ulcer bleeding under proton pump inhibitor use.

Cheng HC, Yang EH, Wu CT, Wang WL, Chen PJ, Lin MY, Sheu BS.

J Formos Med Assoc. 2018 Apr;117(4):316-325. doi: 10.1016/j.jfma.2017.07.006. Epub 2017 Jul 24.


Osteopontin polymorphism increases gastric precancerous intestinal metaplasia susceptibility in Helicobacter pylori infected male.

Chang WL, Lin MY, Kuo HY, Yang HB, Cheng HC, Lu CC, Sheu BS.

Future Oncol. 2017 Jul;13(16):1415-1425. doi: 10.2217/fon-2017-0006. Epub 2017 Jul 7.


Survey of the adherence to the consensus of gastroesophageal reflux disease before and after the implementation course.

Liou JM, Sheu BS, Lee YC, Cheng HC, Chang WL, Wu DC, Hsu PI, Wu CY, Wu MS, Chiu CT, Lin JT.

J Formos Med Assoc. 2018 May;117(5):440-449. doi: 10.1016/j.jfma.2017.05.012. Epub 2017 Jun 13.


Peptic ulcer bleeding patients with Rockall scores ≥6 are at risk of long-term ulcer rebleeding: A 3.5-year prospective longitudinal study.

Yang EH, Cheng HC, Wu CT, Chen WY, Lin MY, Sheu BS.

J Gastroenterol Hepatol. 2018 Jan;33(1):156-163. doi: 10.1111/jgh.13822.


Radical trachelectomy for early stage cervical cancer: A case series and literature review.

Wu CJ, Chang WC, Chen CH, Chen CA, Huang SC, Sheu BC.

Taiwan J Obstet Gynecol. 2017 Apr;56(2):143-146. doi: 10.1016/j.tjog.2016.05.014. Review.


Inactivation of ferric uptake regulator (Fur) attenuates Helicobacter pylori J99 motility by disturbing the flagellar motor switch and autoinducer-2 production.

Lee AY, Kao CY, Wang YK, Lin SY, Lai TY, Sheu BS, Lo CJ, Wu JJ.

Helicobacter. 2017 Aug;22(4). doi: 10.1111/hel.12388. Epub 2017 Apr 12.


The Helicobacter pylori J99 jhp0106 Gene, under the Control of the CsrA/RpoN Regulatory System, Modulates Flagella Formation and Motility.

Kao CY, Chen JW, Wang S, Sheu BS, Wu JJ.

Front Microbiol. 2017 Mar 28;8:483. doi: 10.3389/fmicb.2017.00483. eCollection 2017.


The corpus-predominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia.

Cheng HC, Tsai YC, Yang HB, Yeh YC, Chang WL, Kuo HY, Lu CC, Sheu BS.

Helicobacter. 2017 Aug;22(4). doi: 10.1111/hel.12385. Epub 2017 Mar 22.


Ten days of levofloxacin-containing concomitant therapy can achieve effective Helicobacter pylori eradication in patients with type 2 diabetes.

Yang YJ, Wu CT, Ou HY, Lin CH, Cheng HC, Chang WL, Chen WY, Yang HB, Lu CC, Sheu BS.

Ann Med. 2017 Sep;49(6):479-486. doi: 10.1080/07853890.2017.1294761. Epub 2017 Mar 7.


Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale.

Sheu BS, Wu MS, Chiu CT, Lo JC, Wu DC, Liou JM, Wu CY, Cheng HC, Lee YC, Hsu PI, Chang CC, Chang WL, Lin JT.

Helicobacter. 2017 Jun;22(3). doi: 10.1111/hel.12368. Epub 2017 Jan 8.


MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma.

Lin CH, Tsai CH, Yeh CT, Liang JL, Hung WC, Lin FC, Chang WL, Li HY, Yao YC, Hsu TI, Lee YC, Wang YC, Sheu BS, Lai WW, Calkins MJ, Hsiao M, Lu PJ.

Oncotarget. 2016 Jun 28;7(26):39680-39693. doi: 10.18632/oncotarget.9444.


Concomitant, bismuth quadruple, and 14-day triple therapy in the first-line treatment of Helicobacter pylori: a multicentre, open-label, randomised trial.

Liou JM, Fang YJ, Chen CC, Bair MJ, Chang CY, Lee YC, Chen MJ, Chen CC, Tseng CH, Hsu YC, Lee JY, Yang TH, Luo JC, Chang CC, Chen CY, Chen PY, Shun CT, Hsu WF, Hu WH, Chen YN, Sheu BS, Lin JT, Wu JY, El-Omar EM, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

Lancet. 2016 Nov 12;388(10058):2355-2365. doi: 10.1016/S0140-6736(16)31409-X. Epub 2016 Oct 18.


Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition.

Huang YC, Lee CT, Lee JC, Liu YW, Chen YJ, Tseng JT, Kang JW, Sheu BS, Lin BW, Hung LY.

Oncotarget. 2016 Nov 22;7(47):76852-76866. doi: 10.18632/oncotarget.12719.


Metabolic Interaction of Helicobacter pylori Infection and Gut Microbiota.

Yang YJ, Sheu BS.

Microorganisms. 2016 Feb 16;4(1). pii: E15. doi: 10.3390/microorganisms4010015. Review.


A six-CpG panel with DNA methylation biomarkers predicting treatment response of chemoradiation in esophageal squamous cell carcinoma.

Chang WL, Lai WW, Kuo IY, Lin CY, Lu PJ, Sheu BS, Wang YC.

J Gastroenterol. 2017 Jun;52(6):705-714. doi: 10.1007/s00535-016-1265-2. Epub 2016 Sep 26.


Intraligamental Myomectomy Strategy Using Laparoscopy.

Huang PS, Sheu BC, Huang SC, Chang WC.

J Minim Invasive Gynecol. 2016 Sep-Oct;23(6):954-61. doi: 10.1016/j.jmig.2016.06.007. Epub 2016 Jun 18.


Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus.

Fock KM, Talley N, Goh KL, Sugano K, Katelaris P, Holtmann G, Pandolfino JE, Sharma P, Ang TL, Hongo M, Wu J, Chen M, Choi MG, Law NM, Sheu BS, Zhang J, Ho KY, Sollano J, Rani AA, Kositchaiwat C, Bhatia S.

Gut. 2016 Sep;65(9):1402-15. doi: 10.1136/gutjnl-2016-311715. Epub 2016 Jun 3.


Serum Level of Trefoil Factor 2 can Predict the Extent of Gastric Spasmolytic Polypeptide-Expressing Metaplasia in the H. pylori-Infected Gastric Cancer Relatives.

Kuo HY, Chang WL, Yeh YC, Tsai YC, Wu CT, Cheng HC, Yang HB, Lu CC, Sheu BS.

Helicobacter. 2017 Feb;22(1). doi: 10.1111/hel.12320. Epub 2016 May 25.


Comparison of the laparoscopic versus conventional open method for surgical staging of endometrial carcinoma.

Chu LH, Chang WC, Sheu BC.

Taiwan J Obstet Gynecol. 2016 Apr;55(2):188-92. doi: 10.1016/j.tjog.2016.02.007.


Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis.

Kao CY, Sheu BS, Wu JJ.

Biomed J. 2016 Feb;39(1):14-23. doi: 10.1016/ Epub 2016 Apr 1. Review.


Dynamic response of HPV16/anti-HPV16 pairs with unbinding events studied by atomic force microscopy.

Lin S, Hong CH, Sheu BC, Wu LX, Huang WC, Huang WC, Guo CY.

Biochem Biophys Rep. 2016 Apr 16;6:203-208. doi: 10.1016/j.bbrep.2016.04.008. eCollection 2016 Jul.


Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma.

Wang WL, Chang WL, Yang HB, Wang YC, Chang IW, Lee CT, Chang CY, Lin JT, Sheu BS.

Oncotarget. 2016 Nov 1;7(44):71169-71181. doi: 10.18632/oncotarget.8460.


Risk factors determining the need for second-look endoscopy for peptic ulcer bleeding after endoscopic hemostasis and proton pump inhibitor infusion.

Cheng HC, Wu CT, Chen WY, Yang EH, Chen PJ, Sheu BS.

Endosc Int Open. 2016 Mar;4(3):E255-62. doi: 10.1055/s-0041-111499. Epub 2016 Feb 8.


Highlights from the 2015 Annual Meeting and First International Congress of the Taiwan Association of Gynecology.

Wang PH, Ho CH, Chen YJ, Horng HC, Chang YH, Chao HT, Yen MS, Chow SN, Sheu BC; Taiwan Association of Gynecology Systematic Review Group, Wen KC, Chang YW, Tsui KH, Hung MJ, Huang BS, Chen RJ, Lien YR, Chang WC, Chang TC, Liu JY, Wu WY, Chen TC, Huang JP, Hung JH, Chen KH, Lai TH, Tzeng CR, Wang CJ.

Taiwan J Obstet Gynecol. 2015 Dec;54(6):803-5. doi: 10.1016/j.tjog.2015.10.022. No abstract available.


Medical treatment for heavy menstrual bleeding.

Chen YJ, Li YT, Huang BS, Yen MS, Sheu BC, Chow SN, Wang PH; Taiwan Association of Gynecology Systematic Review Group.

Taiwan J Obstet Gynecol. 2015 Oct;54(5):483-8. doi: 10.1016/j.tjog.2015.08.001. Review.


Regulatory T Cells Suppress Natural Killer Cell Immunity in Patients With Human Cervical Carcinoma.

Chang WC, Li CH, Chu LH, Huang PS, Sheu BC, Huang SC.

Int J Gynecol Cancer. 2016 Jan;26(1):156-62. doi: 10.1097/IGC.0000000000000578.


Gastroesophageal Reflux Disease Diagnosis Using Hierarchical Heterogeneous Descriptor Fusion Support Vector Machine.

Huang CR, Chen YT, Chen WY, Cheng HC, Sheu BS.

IEEE Trans Biomed Eng. 2016 Mar;63(3):588-99. doi: 10.1109/TBME.2015.2466460. Epub 2015 Aug 10.


The effects of narrow-band middle infrared radiation in enhancing the antitumor activity of paclitaxel.

Tsai SR, Sheu BC, Huang PS, Lee SC.

Electromagn Biol Med. 2016;35(2):106-14. doi: 10.3109/15368378.2014.992073. Epub 2015 Jun 26.


Quantification of tumor infiltrating Foxp3+ regulatory T cells enables the identification of high-risk patients for developing synchronous cancers over upper aerodigestive tract.

Wang WL, Chang WL, Yang HB, Chang IW, Lee CT, Chang CY, Lin JT, Sheu BS.

Oral Oncol. 2015 Jul;51(7):698-703. doi: 10.1016/j.oraloncology.2015.04.015. Epub 2015 May 7.


Comparison of Laparoscopic Myomectomy in Large Myomas With and Without Leuprolide Acetate.

Chang WC, Chu LH, Huang PS, Huang SC, Sheu BC.

J Minim Invasive Gynecol. 2015 Sep-Oct;22(6):992-6. doi: 10.1016/j.jmig.2015.04.026. Epub 2015 May 7.


The Primary Resistance of Helicobacter pylori in Taiwan after the National Policy to Restrict Antibiotic Consumption and Its Relation to Virulence Factors-A Nationwide Study.

Liou JM, Chang CY, Chen MJ, Chen CC, Fang YJ, Lee JY, Wu JY, Luo JC, Liou TC, Chang WH, Tseng CH, Wu CY, Yang TH, Chang CC, Wang HP, Sheu BS, Lin JT, Bair MJ, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

PLoS One. 2015 May 5;10(5):e0124199. doi: 10.1371/journal.pone.0124199. eCollection 2015.


Standardized uptake value and apparent diffusion coefficient of endometrial cancer evaluated with integrated whole-body PET/MR: Correlation with pathological prognostic factors.

Shih IL, Yen RF, Chen CA, Chen BB, Wei SY, Chang WC, Sheu BC, Cheng WF, Tseng YH, Chen XJ, Chen CH, Wei LH, Chiang YC, Torng PL, Yen ML, Shih TT.

J Magn Reson Imaging. 2015 Dec;42(6):1723-32. doi: 10.1002/jmri.24932. Epub 2015 Apr 27.


Genomic single nucleotide polymorphisms in the offspring of gastric cancer patients predispose to spasmolytic polypeptide-expressing metaplasia after H. pylori infection.

Tsai YC, Hsiao WH, Lin SH, Yang HB, Cheng HC, Chang WL, Lu CC, Sheu BS.

J Biomed Sci. 2015 Feb 21;22:16. doi: 10.1186/s12929-015-0121-7.


Intracellular Osteopontin Induced by CagA-positive Helicobacter pylori Promotes Beta-catenin Accumulation and Interleukin-8 Secretion in Gastric Epithelial cells.

Chang WL, Yang HB, Cheng HC, Yeh YC, Kao CY, Wu JJ, Lu CC, Sheu BS.

Helicobacter. 2015 Dec;20(6):476-84. doi: 10.1111/hel.12225. Epub 2015 Mar 3.


Genome Sequence and Annotation of Helicobacter pylori Strain Hp238, Isolated from a Taiwanese Patient with Mucosa-Associated Lymphoid Tissue Lymphoma.

Kao CY, Chen JW, Huang YT, Sheu SM, Sheu BS, Wu JJ.

Genome Announc. 2015 Feb 19;3(1). pii: e00006-15. doi: 10.1128/genomeA.00006-15.

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