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Items: 27


Dynamic Changes in Gene Mutational Landscape With Preservation of Core Mutations in Mantle Cell Lymphoma Cells.

Zhang Q, Wang HY, Liu X, Roth MH, Shestov AA, Lee SC, Jain K, Soderquist C, Xiong QB, Ruella M, Strauser H, Glickson JD, Schuster SJ, Ptasznik A, Wasik MA.

Front Oncol. 2019 Jul 3;9:568. doi: 10.3389/fonc.2019.00568. eCollection 2019.


Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.

Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, Blair IA, Glickson JD, Wasik MA.

Mol Cancer Res. 2019 Jun;17(6):1365-1377. doi: 10.1158/1541-7786.MCR-18-0256. Epub 2019 Mar 12.


Brain metabolism under different anesthetic conditions using hyperpolarized [1-13 C]pyruvate and [2-13 C]pyruvate.

Marjańska M, Shestov AA, Deelchand DK, Kittelson E, Henry PG.

NMR Biomed. 2018 Dec;31(12):e4012. doi: 10.1002/nbm.4012. Epub 2018 Oct 1.


A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.

Liberti MV, Dai Z, Wardell SE, Baccile JA, Liu X, Gao X, Baldi R, Mehrmohamadi M, Johnson MO, Madhukar NS, Shestov AA, Chio IIC, Elemento O, Rathmell JC, Schroeder FC, McDonnell DP, Locasale JW.

Cell Metab. 2017 Oct 3;26(4):648-659.e8. doi: 10.1016/j.cmet.2017.08.017. Epub 2017 Sep 14.


Mechanism of antineoplastic activity of lonidamine.

Nath K, Guo L, Nancolas B, Nelson DS, Shestov AA, Lee SC, Roman J, Zhou R, Leeper DB, Halestrap AP, Blair IA, Glickson JD.

Biochim Biophys Acta. 2016 Dec;1866(2):151-162. doi: 10.1016/j.bbcan.2016.08.001. Epub 2016 Aug 4. Review.


A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect.

Dai Z, Shestov AA, Lai L, Locasale JW.

Biophys J. 2016 Sep 6;111(5):1088-100. doi: 10.1016/j.bpj.2016.07.028.


(13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism.

Shestov AA, Lee SC, Nath K, Guo L, Nelson DS, Roman JC, Leeper DB, Wasik MA, Blair IA, Glickson JD.

Front Oncol. 2016 Jun 15;6:135. doi: 10.3389/fonc.2016.00135. eCollection 2016.


Reductive carboxylation supports redox homeostasis during anchorage-independent growth.

Jiang L, Shestov AA, Swain P, Yang C, Parker SJ, Wang QA, Terada LS, Adams ND, McCabe MT, Pietrak B, Schmidt S, Metallo CM, Dranka BP, Schwartz B, DeBerardinis RJ.

Nature. 2016 Apr 14;532(7598):255-8. doi: 10.1038/nature17393. Epub 2016 Apr 6.


Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells.

Shestov AA, Mancuso A, Lee SC, Guo L, Nelson DS, Roman JC, Henry PG, Leeper DB, Blair IA, Glickson JD.

J Biol Chem. 2016 Mar 4;291(10):5157-71. doi: 10.1074/jbc.M115.701862. Epub 2015 Dec 24.


Metabolic Modeling of Dynamic (13)C NMR Isotopomer Data in the Brain In Vivo: Fast Screening of Metabolic Models Using Automated Generation of Differential Equations.

Tiret B, Shestov AA, Valette J, Henry PG.

Neurochem Res. 2015 Dec;40(12):2482-92. doi: 10.1007/s11064-015-1748-1. Epub 2015 Nov 9. Review.


Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine.

Guo L, Shestov AA, Worth AJ, Nath K, Nelson DS, Leeper DB, Glickson JD, Blair IA.

J Biol Chem. 2016 Jan 1;291(1):42-57. doi: 10.1074/jbc.M115.697516. Epub 2015 Oct 31.


Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.

Simões RV, Serganova IS, Kruchevsky N, Leftin A, Shestov AA, Thaler HT, Sukenick G, Locasale JW, Blasberg RG, Koutcher JA, Ackerstaff E.

Neoplasia. 2015 Aug;17(8):671-84. doi: 10.1016/j.neo.2015.08.005.


Characterization of the usage of the serine metabolic network in human cancer.

Mehrmohamadi M, Liu X, Shestov AA, Locasale JW.

Cell Rep. 2014 Nov 20;9(4):1507-19. doi: 10.1016/j.celrep.2014.10.026. Epub 2014 Nov 6.


Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.

Shestov AA, Liu X, Ser Z, Cluntun AA, Hung YP, Huang L, Kim D, Le A, Yellen G, Albeck JG, Locasale JW.

Elife. 2014 Jul 9;3. doi: 10.7554/eLife.03342.


Computational approaches for understanding energy metabolism.

Shestov AA, Barker B, Gu Z, Locasale JW.

Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):733-50. doi: 10.1002/wsbm.1238. Epub 2013 Jul 29. Review.


Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model.

Tzika AA, Fontes-Oliveira CC, Shestov AA, Constantinou C, Psychogios N, Righi V, Mintzopoulos D, Busquets S, Lopez-Soriano FJ, Milot S, Lepine F, Mindrinos MN, Rahme LG, Argiles JM.

Int J Oncol. 2013 Sep;43(3):886-94. doi: 10.3892/ijo.2013.1998. Epub 2013 Jun 28.


Modeling of brain metabolism and pyruvate compartmentation using (13)C NMR in vivo: caution required.

Jeffrey FM, Marin-Valencia I, Good LB, Shestov AA, Henry PG, Pascual JM, Malloy CR.

J Cereb Blood Flow Metab. 2013 Aug;33(8):1160-7. doi: 10.1038/jcbfm.2013.67. Epub 2013 May 8.


Metabolic network analysis of DB1 melanoma cells: how much energy is derived from aerobic glycolysis?

Shestov AA, Mancuso A, Leeper DB, Glickson JD.

Adv Exp Med Biol. 2013;765:265-271. doi: 10.1007/978-1-4614-4989-8_37.


Metabolic modeling of dynamic brain ¹³C NMR multiplet data: concepts and simulations with a two-compartment neuronal-glial model.

Shestov AA, Valette J, Deelchand DK, Uğurbil K, Henry PG.

Neurochem Res. 2012 Nov;37(11):2388-401. doi: 10.1007/s11064-012-0782-5. Epub 2012 Apr 24.


Simultaneous measurement of glucose transport and utilization in the human brain.

Shestov AA, Emir UE, Kumar A, Henry PG, Seaquist ER, Öz G.

Am J Physiol Endocrinol Metab. 2011 Nov;301(5):E1040-9. doi: 10.1152/ajpendo.00110.2011. Epub 2011 Jul 26.


Effect of acute hypoglycemia on human cerebral glucose metabolism measured by ¹³C magnetic resonance spectroscopy.

van de Ven KC, de Galan BE, van der Graaf M, Shestov AA, Henry PG, Tack CJ, Heerschap A.

Diabetes. 2011 May;60(5):1467-73. doi: 10.2337/db10-1592. Epub 2011 Apr 4.


In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-(13)C]pyruvate and [2-(13)C]pyruvate.

Marjańska M, Iltis I, Shestov AA, Deelchand DK, Nelson C, Uğurbil K, Henry PG.

J Magn Reson. 2010 Oct;206(2):210-8. doi: 10.1016/j.jmr.2010.07.006. Epub 2010 Jul 16.


Acetate transport and utilization in the rat brain.

Deelchand DK, Shestov AA, Koski DM, Uğurbil K, Henry PG.

J Neurochem. 2009 May;109 Suppl 1:46-54. doi: 10.1111/j.1471-4159.2009.05895.x.


Simultaneous measurement of neuronal and glial metabolism in rat brain in vivo using co-infusion of [1,6-13C2]glucose and [1,2-13C2]acetate.

Deelchand DK, Nelson C, Shestov AA, Uğurbil K, Henry PG.

J Magn Reson. 2009 Feb;196(2):157-63. doi: 10.1016/j.jmr.2008.11.001. Epub 2008 Nov 7.


On the reliability of (13)C metabolic modeling with two-compartment neuronal-glial models.

Shestov AA, Valette J, Uğurbil K, Henry PG.

J Neurosci Res. 2007 Nov 15;85(15):3294-303.


Kinetics of the unimolecular decomposition of the 2-chloroallyl radical.

Shestov AA, Popov KV, Knyazev VD.

J Phys Chem A. 2005 Sep 15;109(36):8149-57.


Kinetics of the CH2Cl + CH3 and CHCl2 + CH3 radical-radical reactions.

Shestov AA, Popov KV, Knyazev VD.

J Phys Chem A. 2005 Jul 21;109(28):6249-54.


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