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Items: 1 to 50 of 144


A p53-responsive microRNA network promotes cancer cell quiescence.

La T, Liu GZ, Farrelly M, Cole N, Feng YC, Zhang YY, Sherwin SK, Yari H, Tabatabaee H, Yan XG, Guo ST, Liu T, Thorne RF, Jin L, Zhang XD.

Cancer Res. 2018 Oct 9. pii: canres.1886.2018. doi: 10.1158/0008-5472.CAN-18-1886. [Epub ahead of print]


Aberration recovery by imaging a weak diffuser.

Gunjala G, Sherwin S, Shanker A, Waller L.

Opt Express. 2018 Aug 6;26(16):21054-21068. doi: 10.1364/OE.26.021054.


Computational modelling for decision-making: where, why, what, who and how.

Calder M, Craig C, Culley D, de Cani R, Donnelly CA, Douglas R, Edmonds B, Gascoigne J, Gilbert N, Hargrove C, Hinds D, Lane DC, Mitchell D, Pavey G, Robertson D, Rosewell B, Sherwin S, Walport M, Wilson A.

R Soc Open Sci. 2018 Jun 20;5(6):172096. doi: 10.1098/rsos.172096. eCollection 2018 Jun. Review.


Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells.

Wang YF, Liu F, Sherwin S, Farrelly M, Yan XG, Croft A, Liu T, Jin L, Zhang XD, Jiang CC.

J Invest Dermatol. 2018 Apr;138(4):922-932. doi: 10.1016/j.jid.2017.11.009. Epub 2017 Nov 22.


Visualization of three pathways for macromolecule transport across cultured endothelium and their modification by flow.

Ghim M, Alpresa P, Yang SW, Braakman ST, Gray SG, Sherwin SJ, van Reeuwijk M, Weinberg PD.

Am J Physiol Heart Circ Physiol. 2017 Nov 1;313(5):H959-H973. doi: 10.1152/ajpheart.00218.2017. Epub 2017 Jul 28.


Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer.

Hege KM, Bergsland EK, Fisher GA, Nemunaitis JJ, Warren RS, McArthur JG, Lin AA, Schlom J, June CH, Sherwin SA.

J Immunother Cancer. 2017 Mar 21;5:22. doi: 10.1186/s40425-017-0222-9. eCollection 2017.


Noradrenaline has opposing effects on the hydraulic conductance of arterial intima and media.

Chooi KY, Comerford A, Sherwin SJ, Weinberg PD.

J Biomech. 2017 Mar 21;54:4-10. doi: 10.1016/j.jbiomech.2017.01.027. Epub 2017 Jan 30.


Functional identification of a novel transcript variant of INPP4B in human colon and breast cancer cells.

Croft A, Guo ST, Sherwin S, Farrelly M, Yan XG, Zhang XD, Jiang CC.

Biochem Biophys Res Commun. 2017 Mar 25;485(1):47-53. doi: 10.1016/j.bbrc.2017.02.012. Epub 2017 Feb 8.


Understanding the fluid mechanics behind transverse wall shear stress.

Mohamied Y, Sherwin SJ, Weinberg PD.

J Biomech. 2017 Jan 4;50:102-109. doi: 10.1016/j.jbiomech.2016.11.035. Epub 2016 Nov 11.


Zebrafish Model for Functional Screening of Flow-Responsive Genes.

Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M, Feng S, Souilhol C, Bowden N, Ashton JP, Walczak H, Firmin D, Krams R, Mason JC, Haskard DO, Sherwin S, Ridger V, Chico TJ, Evans PC.

Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):130-143. doi: 10.1161/ATVBAHA.116.308502. Epub 2016 Nov 10.


Reactive Oxygen Species Dictate the Apoptotic Response of Melanoma Cells to TH588.

Wang JY, Jin L, Yan XG, Sherwin S, Farrelly M, Zhang YY, Liu F, Wang CY, Guo ST, Yari H, La T, McFarlane J, Lei FX, Tabatabaee H, Chen JZ, Croft A, Jiang CC, Zhang XD.

J Invest Dermatol. 2016 Nov;136(11):2277-2286. doi: 10.1016/j.jid.2016.06.625. Epub 2016 Jul 15.


Intimal and medial contributions to the hydraulic resistance of the arterial wall at different pressures: a combined computational and experimental study.

Chooi KY, Comerford A, Sherwin SJ, Weinberg PD.

J R Soc Interface. 2016 Jun;13(119). pii: 20160234. doi: 10.1098/rsif.2016.0234.


Automated fiducial point selection for reducing registration error in the co-localisation of left atrium electroanatomic and imaging data.

Ali RL, Cantwell CD, Qureshi NA, Roney CH, Lim PB, Sherwin SJ, Siggers JH, Peters NS.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:1989-92. doi: 10.1109/EMBC.2015.7318775.


Techniques for automated local activation time annotation and conduction velocity estimation in cardiac mapping.

Cantwell CD, Roney CH, Ng FS, Siggers JH, Sherwin SJ, Peters NS.

Comput Biol Med. 2015 Oct 1;65:229-42. doi: 10.1016/j.compbiomed.2015.04.027. Epub 2015 Apr 25.


From h to p efficiently: optimal implementation strategies for explicit time-dependent problems using the spectral/hp element method.

Bolis A, Cantwell CD, Kirby RM, Sherwin SJ.

Int J Numer Methods Fluids. 2014 Jul 20;75(8):591-607. Epub 2014 Apr 11.


An automated algorithm for determining conduction velocity, wavefront direction and origin of focal cardiac arrhythmias using a multipolar catheter.

Roney CH, Cantwell CD, Qureshi NA, Ali RL, Chang ET, Lim PB, Sherwin SJ, Peters NS, Siggers JH, Ng FS.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1583-6. doi: 10.1109/EMBC.2014.6943906.


Elevated uptake of plasma macromolecules by regions of arterial wall predisposed to plaque instability in a mouse model.

Mohri Z, Rowland EM, Clarke LA, De Luca A, Peiffer V, Krams R, Sherwin SJ, Weinberg PD.

PLoS One. 2014 Dec 22;9(12):e115728. doi: 10.1371/journal.pone.0115728. eCollection 2014.


Change of direction in the biomechanics of atherosclerosis.

Mohamied Y, Rowland EM, Bailey EL, Sherwin SJ, Schwartz MA, Weinberg PD.

Ann Biomed Eng. 2015 Jan;43(1):16-25. doi: 10.1007/s10439-014-1095-4. Epub 2014 Aug 20. Review.


A combined numerical and experimental framework for determining permeability properties of the arterial media.

Comerford A, Chooi KY, Nowak M, Weinberg PD, Sherwin SJ.

Biomech Model Mechanobiol. 2015 Apr;14(2):297-313. doi: 10.1007/s10237-014-0604-6. Epub 2014 Jul 17.


High-order spectral/hp element discretisation for reaction-diffusion problems on surfaces: Application to cardiac electrophysiology.

Cantwell CD, Yakovlev S, Kirby RM, Peters NS, Sherwin SJ.

J Comput Phys. 2014 Jan 15;257(PA):813-829.


Disturbed flow promotes endothelial senescence via a p53-dependent pathway.

Warboys CM, de Luca A, Amini N, Luong L, Duckles H, Hsiao S, White A, Biswas S, Khamis R, Chong CK, Cheung WM, Sherwin SJ, Bennett MR, Gil J, Mason JC, Haskard DO, Evans PC.

Arterioscler Thromb Vasc Biol. 2014 May;34(5):985-95. doi: 10.1161/ATVBAHA.114.303415. Epub 2014 Mar 20.


Computation in the rabbit aorta of a new metric - the transverse wall shear stress - to quantify the multidirectional character of disturbed blood flow.

Peiffer V, Sherwin SJ, Weinberg PD.

J Biomech. 2013 Oct 18;46(15):2651-8. doi: 10.1016/j.jbiomech.2013.08.003. Epub 2013 Aug 30.


Does low and oscillatory wall shear stress correlate spatially with early atherosclerosis? A systematic review.

Peiffer V, Sherwin SJ, Weinberg PD.

Cardiovasc Res. 2013 Jul 15;99(2):242-50. doi: 10.1093/cvr/cvt044. Epub 2013 Mar 3. Review.


A novel method for quantifying spatial correlations between patterns of atherosclerosis and hemodynamic factors.

Peiffer V, Bharath AA, Sherwin SJ, Weinberg PD.

J Biomech Eng. 2013 Feb;135(2):021023. doi: 10.1115/1.4023381.


Variability of computational fluid dynamics solutions for pressure and flow in a giant aneurysm: the ASME 2012 Summer Bioengineering Conference CFD Challenge.

Steinman DA, Hoi Y, Fahy P, Morris L, Walsh MT, Aristokleous N, Anayiotos AS, Papaharilaou Y, Arzani A, Shadden SC, Berg P, Janiga G, Bols J, Segers P, Bressloff NW, Cibis M, Gijsen FH, Cito S, Pallarés J, Browne LD, Costelloe JA, Lynch AG, Degroote J, Vierendeels J, Fu W, Qiao A, Hodis S, Kallmes DF, Kalsi H, Long Q, Kheyfets VO, Finol EA, Kono K, Malek AM, Lauric A, Menon PG, Pekkan K, Esmaily Moghadam M, Marsden AL, Oshima M, Katagiri K, Peiffer V, Mohamied Y, Sherwin SJ, Schaller J, Goubergrits L, Usera G, Mendina M, Valen-Sendstad K, Habets DF, Xiang J, Meng H, Yu Y, Karniadakis GE, Shaffer N, Loth F.

J Biomech Eng. 2013 Feb;135(2):021016. doi: 10.1115/1.4023382.


Effect of aortic taper on patterns of blood flow and wall shear stress in rabbits: association with age.

Peiffer V, Rowland EM, Cremers SG, Weinberg PD, Sherwin SJ.

Atherosclerosis. 2012 Jul;223(1):114-21. doi: 10.1016/j.atherosclerosis.2012.04.020. Epub 2012 May 15.


What matters to users of services? An explorative study to promote shared decision making in health care.

Padgett K, Rhodes C, Lumb M, Morris P, Sherwin S, Symons J, Tate J, Townend K.

Health Expect. 2014 Jun;17(3):418-28. doi: 10.1111/j.1369-7625.2012.00767.x. Epub 2012 Mar 6.


Pulse wave propagation in a model human arterial network: Assessment of 1-D visco-elastic simulations against in vitro measurements.

Alastruey J, Khir AW, Matthys KS, Segers P, Sherwin SJ, Verdonck PR, Parker KH, Peiró J.

J Biomech. 2011 Aug 11;44(12):2250-8. doi: 10.1016/j.jbiomech.2011.05.041. Epub 2011 Jul 2.


SHINE on the midlands.

Hawkins-Dady H, Sherwin S.

Community Pract. 2011 May;84(5):12. No abstract available.


Blood flow in the rabbit aortic arch and descending thoracic aorta.

Vincent PE, Plata AM, Hunt AA, Weinberg PD, Sherwin SJ.

J R Soc Interface. 2011 Dec 7;8(65):1708-19. doi: 10.1098/rsif.2011.0116. Epub 2011 May 18.


Effect of reverse flow on the pattern of wall shear stress near arterial branches.

Kazakidi A, Plata AM, Sherwin SJ, Weinberg PD.

J R Soc Interface. 2011 Nov 7;8(64):1594-603. doi: 10.1098/rsif.2011.0108. Epub 2011 Apr 20.


Looking backwards, looking forward: hopes for bioethics' next twenty-five years.

Sherwin S.

Bioethics. 2011 Feb;25(2):75-82. doi: 10.1111/j.1467-8519.2010.01866.x.


One-dimensional computational model of pulse wave propagation in the human bronchial tree.

Clavica F, Alastruey J, Borlotti A, Sherwin SJ, Khir AW.

Conf Proc IEEE Eng Med Biol Soc. 2010;2010:2473-6. doi: 10.1109/IEMBS.2010.5626559.


Theoretical models for coronary vascular biomechanics: progress & challenges.

Waters SL, Alastruey J, Beard DA, Bovendeerd PH, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, van de Vosse FN.

Prog Biophys Mol Biol. 2011 Jan;104(1-3):49-76. doi: 10.1016/j.pbiomolbio.2010.10.001. Epub 2010 Oct 30. Review.


A relational perspective on autonomy for older adults residing in nursing homes.

Sherwin S, Winsby M.

Health Expect. 2011 Jun;14(2):182-90. doi: 10.1111/j.1369-7625.2010.00638.x. Epub 2010 Oct 28.


BIO's track record on emerging companies.

King RK, Sherwin SA.

Nat Biotechnol. 2010 May;28(5):406. doi: 10.1038/nbt0510-406. No abstract available.


The effect of the endothelial glycocalyx layer on concentration polarisation of low density lipoprotein in arteries.

Vincent PE, Sherwin SJ, Weinberg PD.

J Theor Biol. 2010 Jul 7;265(1):1-17. doi: 10.1016/j.jtbi.2010.04.015. Epub 2010 Apr 21.


Endothelial nitric oxide production and transport in flow chambers: The importance of convection.

Plata AM, Sherwin SJ, Krams R.

Ann Biomed Eng. 2010 Sep;38(9):2805-16. doi: 10.1007/s10439-010-0039-x.


Re-visioning public health ethics: a relational perspective.

Kenny NP, Sherwin SB, Baylis FE.

Can J Public Health. 2010 Jan-Feb;101(1):9-11.


Reply to 'cord clamp insult may predispose to SIDS'.

Alastruey J, Sherwin SJ, Parker KH, Rubens DD.

Early Hum Dev. 2010 Jan;86(1):67. doi: 10.1016/j.earlhumdev.2009.12.002. Epub 2010 Jan 13. No abstract available.


One-dimensional modelling of pulse wave propagation in human airway bifurcations in space-time variables.

Clavica F, Alastruey J, Sherwin SJ, Khir AW.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:5482-5. doi: 10.1109/IEMBS.2009.5334564.


A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting stents.

Moore P, Barlis P, Spiro J, Ghimire G, Roughton M, Di Mario C, Wallis W, Ilsley C, Mitchell A, Mason M, Kharbanda R, Vincent P, Sherwin S, Dalby M.

JACC Cardiovasc Interv. 2009 May;2(5):437-44. doi: 10.1016/j.jcin.2009.01.010.


Placental transfusion insult in the predisposition for SIDS: a mathematical study.

Alastruey J, Sherwin SJ, Parker KH, Rubens DD.

Early Hum Dev. 2009 Jul;85(7):455-9. doi: 10.1016/j.earlhumdev.2009.04.001. Epub 2009 May 14.


The effect of a spatially heterogeneous transmural water flux on concentration polarization of low density lipoprotein in arteries.

Vincent PE, Sherwin SJ, Weinberg PD.

Biophys J. 2009 Apr 22;96(8):3102-15. doi: 10.1016/j.bpj.2009.01.022.


Mixing through stirring of steady flow in small amplitude helical tubes.

Cookson AN, Doorly DJ, Sherwin SJ.

Ann Biomed Eng. 2009 Apr;37(4):710-21. doi: 10.1007/s10439-009-9636-y. Epub 2009 Jan 16.


Effect of Reynolds number and flow division on patterns of haemodynamic wall shear stress near branch points in the descending thoracic aorta.

Kazakidi A, Sherwin SJ, Weinberg PD.

J R Soc Interface. 2009 Jun 6;6(35):539-48. doi: 10.1098/rsif.2008.0323. Epub 2008 Sep 23.


Automatic reconstruction of a patient-specific high-order surface representation and its application to mesh generation for CFD calculations.

Peiró J, Sherwin SJ, Giordana S.

Med Biol Eng Comput. 2008 Nov;46(11):1069-83. doi: 10.1007/s11517-008-0390-3. Epub 2008 Sep 16. Review.


We speak for small biotech.

Sherwin SA.

Nat Biotechnol. 2008 Jan;26(1):27. doi: 10.1038/nbt0108-27a. No abstract available.


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