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Items: 1 to 50 of 224

1.

Dynamic architecture of the Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF.

Rajasekar KV, Baker R, Fisher GLM, Bolla JR, Mäkelä J, Tang M, Zawadzka K, Koczy O, Wagner F, Robinson CV, Arciszewska LK, Sherratt DJ.

Nucleic Acids Res. 2019 Oct 10;47(18):9696-9707. doi: 10.1093/nar/gkz696.

2.

Self-organised segregation of bacterial chromosomal origins.

Hofmann A, Mäkelä J, Sherratt DJ, Heermann D, Murray SM.

Elife. 2019 Aug 9;8. pii: e46564. doi: 10.7554/eLife.46564.

3.

The journey of a molecular detective.

Sherratt D.

Heredity (Edinb). 2019 Jul;123(1):18-22. doi: 10.1038/s41437-019-0216-0. Epub 2019 Jun 12. Review. No abstract available.

PMID:
31189908
4.

The bacterial cell cycle, chromosome inheritance and cell growth.

Reyes-Lamothe R, Sherratt DJ.

Nat Rev Microbiol. 2019 Aug;17(8):467-478. doi: 10.1038/s41579-019-0212-7. Review.

PMID:
31164753
5.

Single-molecule imaging of DNA gyrase activity in living Escherichia coli.

Stracy M, Wollman AJM, Kaja E, Gapinski J, Lee JE, Leek VA, McKie SJ, Mitchenall LA, Maxwell A, Sherratt DJ, Leake MC, Zawadzki P.

Nucleic Acids Res. 2019 Jan 10;47(1):210-220. doi: 10.1093/nar/gky1143.

6.

Competition between DivIVA and the nucleoid for ParA binding promotes segrosome separation and modulates mycobacterial cell elongation.

Pióro M, Małecki T, Portas M, Magierowska I, Trojanowski D, Sherratt D, Zakrzewska-Czerwińska J, Ginda K, Jakimowicz D.

Mol Microbiol. 2019 Jan;111(1):204-220. doi: 10.1111/mmi.14149. Epub 2018 Nov 11.

PMID:
30318635
7.

MukB ATPases are regulated independently by the N- and C-terminal domains of MukF kleisin.

Zawadzka K, Zawadzki P, Baker R, Rajasekar KV, Wagner F, Sherratt DJ, Arciszewska LK.

Elife. 2018 Jan 11;7. pii: e31522. doi: 10.7554/eLife.31522.

8.

Direct observation of end resection by RecBCD during double-stranded DNA break repair in vivo.

Wiktor J, van der Does M, Büller L, Sherratt DJ, Dekker C.

Nucleic Acids Res. 2018 Feb 28;46(4):1821-1833. doi: 10.1093/nar/gkx1290.

9.

Pathways of DNA unlinking: A story of stepwise simplification.

Stolz R, Yoshida M, Brasher R, Flanner M, Ishihara K, Sherratt DJ, Shimokawa K, Vazquez M.

Sci Rep. 2017 Sep 29;7(1):12420. doi: 10.1038/s41598-017-12172-2.

10.

Experiences of establishing an academic early phase clinical trials unit.

Brown SR, Sherratt D, Booth G, Brown J, Collinson F, Gregory W, Flanagan L.

Clin Trials. 2017 Aug;14(4):349-356. doi: 10.1177/1740774517710250. Epub 2017 May 22.

11.

Exploring global recognition of quality midwifery education: Vision or fiction?

Luyben A, Barger M, Avery M, Bharj KK, O'Connell R, Fleming V, Thompson J, Sherratt D.

Women Birth. 2017 Jun;30(3):184-192. doi: 10.1016/j.wombi.2017.03.001. Epub 2017 May 10.

PMID:
28501372
12.

Single-Molecule Analysis of Bacterial DNA Repair and Mutagenesis.

Uphoff S, Sherratt DJ.

Annu Rev Biophys. 2017 May 22;46:411-432. doi: 10.1146/annurev-biophys-070816-034106. Epub 2017 Mar 24. Review.

PMID:
28375733
13.

Chromosome stitch-up?

Sherratt DJ.

Science. 2017 Feb 3;355(6324):460-461. doi: 10.1126/science.aam7183. No abstract available.

PMID:
28154037
14.

Activation of Xer-recombination at dif: structural basis of the FtsKγ-XerD interaction.

Keller AN, Xin Y, Boer S, Reinhardt J, Baker R, Arciszewska LK, Lewis PJ, Sherratt DJ, Löwe J, Grainge I.

Sci Rep. 2016 Oct 6;6:33357. doi: 10.1038/srep33357.

15.

Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli.

Stracy M, Jaciuk M, Uphoff S, Kapanidis AN, Nowotny M, Sherratt DJ, Zawadzki P.

Nat Commun. 2016 Aug 26;7:12568. doi: 10.1038/ncomms12568.

16.

Whole-Genome Comparative Analysis of Two Carbapenem-Resistant ST-258 Klebsiella pneumoniae Strains Isolated during a North-Eastern Ohio Outbreak: Differences within the High Heterogeneity Zones.

Ramirez MS, Xie G, Traglia GM, Johnson SL, Davenport KW, van Duin D, Ramazani A, Perez F, Jacobs MR, Sherratt DJ, Bonomo RA, Chain PS, Tolmasky ME.

Genome Biol Evol. 2016 Jul 3;8(6):2036-43. doi: 10.1093/gbe/evw135.

17.

The MUK five protocol: a phase II randomised, controlled, parallel group, multi-centre trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs. cyclophosphamide, bortezomib (Velcade) and dexamethasone (CVD) for first relapse and primary refractory multiple myeloma.

Brown S, Hinsley S, Ballesteros M, Bourne S, McGarry P, Sherratt D, Flanagan L, Gregory W, Cavenagh J, Owen R, Williams C, Kaiser M, Low E, Yong K; Myeloma UK Clinical Trials Network.

BMC Hematol. 2016 May 17;16:14. doi: 10.1186/s12878-016-0053-9. eCollection 2016.

18.

The progression of replication forks at natural replication barriers in live bacteria.

Moolman MC, Tiruvadi Krishnan S, Kerssemakers JW, de Leeuw R, Lorent V, Sherratt DJ, Dekker NH.

Nucleic Acids Res. 2016 Jul 27;44(13):6262-73. doi: 10.1093/nar/gkw397. Epub 2016 May 10.

19.

CRISPR-mediated control of the bacterial initiation of replication.

Wiktor J, Lesterlin C, Sherratt DJ, Dekker C.

Nucleic Acids Res. 2016 May 5;44(8):3801-10. doi: 10.1093/nar/gkw214. Epub 2016 Apr 1.

20.

Oscillation helps to get division right.

Sherratt DJ.

Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):2803-5. doi: 10.1073/pnas.1601792113. Epub 2016 Mar 4. No abstract available.

21.

Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.

Uphoff S, Lord ND, Okumus B, Potvin-Trottier L, Sherratt DJ, Paulsson J.

Science. 2016 Mar 4;351(6277):1094-7. doi: 10.1126/science.aac9786.

22.

MatP regulates the coordinated action of topoisomerase IV and MukBEF in chromosome segregation.

Nolivos S, Upton AL, Badrinarayanan A, Müller J, Zawadzka K, Wiktor J, Gill A, Arciszewska L, Nicolas E, Sherratt D.

Nat Commun. 2016 Jan 28;7:10466. doi: 10.1038/ncomms10466.

23.

The Localization and Action of Topoisomerase IV in Escherichia coli Chromosome Segregation Is Coordinated by the SMC Complex, MukBEF.

Zawadzki P, Stracy M, Ginda K, Zawadzka K, Lesterlin C, Kapanidis AN, Sherratt DJ.

Cell Rep. 2015 Dec 22;13(11):2587-2596. doi: 10.1016/j.celrep.2015.11.034. Epub 2015 Dec 10.

24.

Assembly, translocation, and activation of XerCD-dif recombination by FtsK translocase analyzed in real-time by FRET and two-color tethered fluorophore motion.

May PF, Zawadzki P, Sherratt DJ, Kapanidis AN, Arciszewska LK.

Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5133-41. doi: 10.1073/pnas.1510814112. Epub 2015 Aug 31.

25.

Shaping the landscape of the Escherichia coli chromosome: replication-transcription encounters in cells with an ectopic replication origin.

Ivanova D, Taylor T, Smith SL, Dimude JU, Upton AL, Mehrjouy MM, Skovgaard O, Sherratt DJ, Retkute R, Rudolph CJ.

Nucleic Acids Res. 2015 Sep 18;43(16):7865-77. doi: 10.1093/nar/gkv704. Epub 2015 Jul 8.

26.

Bendamustine, thalidomide and dexamethasone combination therapy for relapsed/refractory myeloma patients: results of the MUKone randomized dose selection trial.

Schey S, Brown SR, Tillotson AL, Yong K, Williams C, Davies F, Morgan G, Cavenagh J, Cook G, Cook M, Orti G, Morris C, Sherratt D, Flanagan L, Gregory W, Cavet J; Myeloma UK Early Phase Clinical Trial Network.

Br J Haematol. 2015 Aug;170(3):336-48. doi: 10.1111/bjh.13435. Epub 2015 Apr 20.

PMID:
25891006
27.

Slow unloading leads to DNA-bound β2-sliding clamp accumulation in live Escherichia coli cells.

Moolman MC, Krishnan ST, Kerssemakers JW, van den Berg A, Tulinski P, Depken M, Reyes-Lamothe R, Sherratt DJ, Dekker NH.

Nat Commun. 2014 Dec 18;5:5820. doi: 10.1038/ncomms6820.

28.

MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae.

Fleurie A, Lesterlin C, Manuse S, Zhao C, Cluzel C, Lavergne JP, Franz-Wachtel M, Macek B, Combet C, Kuru E, VanNieuwenhze MS, Brun YV, Sherratt D, Grangeasse C.

Nature. 2014 Dec 11;516(7530):259-262. doi: 10.1038/nature13966. Epub 2014 Nov 26.

29.

Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imaging.

May PFJ, Pinkney JNM, Zawadzki P, Evans GW, Sherratt DJ, Kapanidis AN.

Biophys J. 2014 Sep 2;107(5):1205-1216. doi: 10.1016/j.bpj.2014.07.024. Erratum in: Biophys J. 2015 Jul 21;109(2):457.

30.

Evidence for divisome localization mechanisms independent of the Min system and SlmA in Escherichia coli.

Bailey MW, Bisicchia P, Warren BT, Sherratt DJ, Männik J.

PLoS Genet. 2014 Aug 7;10(8):e1004504. doi: 10.1371/journal.pgen.1004504. eCollection 2014 Aug.

31.

Single-molecule imaging of FtsK translocation reveals mechanistic features of protein-protein collisions on DNA.

Lee JY, Finkelstein IJ, Arciszewska LK, Sherratt DJ, Greene EC.

Mol Cell. 2014 Jun 5;54(5):832-43. doi: 10.1016/j.molcel.2014.03.033. Epub 2014 Apr 24.

32.

Visualizing protein-DNA interactions in live bacterial cells using photoactivated single-molecule tracking.

Uphoff S, Sherratt DJ, Kapanidis AN.

J Vis Exp. 2014 Mar 10;(85). doi: 10.3791/51177.

33.

The SMC complex MukBEF recruits topoisomerase IV to the origin of replication region in live Escherichia coli.

Nicolas E, Upton AL, Uphoff S, Henry O, Badrinarayanan A, Sherratt D.

MBio. 2014 Feb 11;5(1):e01001-13. doi: 10.1128/mBio.01001-13.

34.

Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells.

Pimentel B, Nair R, Bermejo-Rodríguez C, Preston MA, Agu CA, Wang X, Bernal JA, Sherratt DJ, de la Cueva-Méndez G.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2734-9. doi: 10.1073/pnas.1308241111. Epub 2014 Jan 21.

35.

RecA bundles mediate homology pairing between distant sisters during DNA break repair.

Lesterlin C, Ball G, Schermelleh L, Sherratt DJ.

Nature. 2014 Feb 13;506(7487):249-53. doi: 10.1038/nature12868. Epub 2013 Dec 22.

36.

MinC, MinD, and MinE drive counter-oscillation of early-cell-division proteins prior to Escherichia coli septum formation.

Bisicchia P, Arumugam S, Schwille P, Sherratt D.

MBio. 2013 Dec 10;4(6):e00856-13. doi: 10.1128/mBio.00856-13.

37.

The N-terminal membrane-spanning domain of the Escherichia coli DNA translocase FtsK hexamerizes at midcell.

Bisicchia P, Steel B, Mariam Debela MH, Löwe J, Sherratt D.

MBio. 2013 Dec 3;4(6):e00800-13. doi: 10.1128/mBio.00800-13.

38.

FtsK-dependent XerCD-dif recombination unlinks replication catenanes in a stepwise manner.

Shimokawa K, Ishihara K, Grainge I, Sherratt DJ, Vazquez M.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):20906-11. doi: 10.1073/pnas.1308450110. Epub 2013 Nov 11.

39.

High-copy bacterial plasmids diffuse in the nucleoid-free space, replicate stochastically and are randomly partitioned at cell division.

Reyes-Lamothe R, Tran T, Meas D, Lee L, Li AM, Sherratt DJ, Tolmasky ME.

Nucleic Acids Res. 2014 Jan;42(2):1042-51. doi: 10.1093/nar/gkt918. Epub 2013 Oct 16.

40.

The bacterial chromosome: architecture and action of bacterial SMC and SMC-like complexes.

Nolivos S, Sherratt D.

FEMS Microbiol Rev. 2014 May;38(3):380-92. doi: 10.1111/1574-6976.12045. Epub 2013 Nov 18. Review.

41.

Conformational transitions during FtsK translocase activation of individual XerCD-dif recombination complexes.

Zawadzki P, May PF, Baker RA, Pinkney JN, Kapanidis AN, Sherratt DJ, Arciszewska LK.

Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17302-7. doi: 10.1073/pnas.1311065110. Epub 2013 Oct 7.

42.

Replication-fork dynamics.

Duderstadt KE, Reyes-Lamothe R, van Oijen AM, Sherratt DJ.

Cold Spring Harb Perspect Biol. 2014 Jan 1;6(1). pii: a010157. doi: 10.1101/cshperspect.a010157. Review.

43.

Single-molecule DNA repair in live bacteria.

Uphoff S, Reyes-Lamothe R, Garza de Leon F, Sherratt DJ, Kapanidis AN.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8063-8. doi: 10.1073/pnas.1301804110. Epub 2013 Apr 29.

44.

Plasmid partition: sisters drifting apart.

Sherratt D.

EMBO J. 2013 May 2;32(9):1208-10. doi: 10.1038/emboj.2013.84. Epub 2013 Apr 5. No abstract available.

45.

Genome organization and regulation.

Sherratt D.

Mol Biol Cell. 2013 Mar;24(6):675. doi: 10.1091/mbc.E12-12-0876. No abstract available.

46.

Breaking symmetry in SMCs.

Upton AL, Sherratt DJ.

Nat Struct Mol Biol. 2013 Mar;20(3):246-9. doi: 10.1038/nsmb.2525. No abstract available.

PMID:
23463306
47.

Hydroxy-terminated conjugated polymer nanoparticles have near-unity bright fraction and reveal cholesterol-dependence of IGF1R nanodomains.

Koner AL, Krndija D, Hou Q, Sherratt DJ, Howarth M.

ACS Nano. 2013 Feb 26;7(2):1137-44. doi: 10.1021/nn3042122. Epub 2013 Jan 30.

48.

Capturing reaction paths and intermediates in Cre-loxP recombination using single-molecule fluorescence.

Pinkney JN, Zawadzki P, Mazuryk J, Arciszewska LK, Sherratt DJ, Kapanidis AN.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20871-6. doi: 10.1073/pnas.1211922109. Epub 2012 Nov 26.

49.

In vivo architecture and action of bacterial structural maintenance of chromosome proteins.

Badrinarayanan A, Reyes-Lamothe R, Uphoff S, Leake MC, Sherratt DJ.

Science. 2012 Oct 26;338(6106):528-31. doi: 10.1126/science.1227126.

50.

Chromosome replication and segregation in bacteria.

Reyes-Lamothe R, Nicolas E, Sherratt DJ.

Annu Rev Genet. 2012;46:121-43. doi: 10.1146/annurev-genet-110711-155421. Epub 2012 Aug 28. Review.

PMID:
22934648

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