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Items: 1 to 50 of 125

1.

Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.

Krishnan S, Ding Y, Saeidi N, Choi M, Sridharan GV, Sherr DH, Yarmush ML, Alaniz RC, Jayaraman A, Lee K.

Cell Rep. 2019 Sep 17;28(12):3285. doi: 10.1016/j.celrep.2019.08.080. No abstract available.

2.

The Carcinogenome Project: In Vitro Gene Expression Profiling of Chemical Perturbations to Predict Long-Term Carcinogenicity.

Li A, Lu X, Natoli T, Bittker J, Sipes NS, Subramanian A, Auerbach S, Sherr DH, Monti S.

Environ Health Perspect. 2019 Apr;127(4):47002. doi: 10.1289/EHP3986.

3.

Inflammatory breast cancer: Activation of the aryl hydrocarbon receptor and its target CYP1B1 correlates closely with Wnt5a/b-β-catenin signalling, the stem cell phenotype and disease progression.

Mohamed HT, Gadalla R, El-Husseiny N, Hassan H, Wang Z, Ibrahim SA, El-Shinawi M, Sherr DH, Mohamed MM.

J Adv Res. 2018 Dec 8;16:75-86. doi: 10.1016/j.jare.2018.11.006. eCollection 2019 Mar.

4.

Old Receptor, New Tricks-The Ever-Expanding Universe of Aryl Hydrocarbon Receptor Functions. Report from the 4th AHR Meeting, 29⁻31 August 2018 in Paris, France.

Esser C, Lawrence BP, Sherr DH, Perdew GH, Puga A, Barouki R, Coumoul X.

Int J Mol Sci. 2018 Nov 15;19(11). pii: E3603. doi: 10.3390/ijms19113603.

5.

Heavy Metal Neurotoxicants Induce ALS-Linked TDP-43 Pathology.

Ash PEA, Dhawan U, Boudeau S, Lei S, Carlomagno Y, Knobel M, Al Mohanna LFA, Boomhower SR, Newland MC, Sherr DH, Wolozin B.

Toxicol Sci. 2019 Jan 1;167(1):105-115. doi: 10.1093/toxsci/kfy267.

PMID:
30371865
6.

Towards Resolving the Pro- and Anti-Tumor Effects of the Aryl Hydrocarbon Receptor.

Narasimhan S, Stanford Zulick E, Novikov O, Parks AJ, Schlezinger JJ, Wang Z, Laroche F, Feng H, Mulas F, Monti S, Sherr DH.

Int J Mol Sci. 2018 May 7;19(5). pii: E1388. doi: 10.3390/ijms19051388.

7.

Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.

Krishnan S, Ding Y, Saedi N, Choi M, Sridharan GV, Sherr DH, Yarmush ML, Alaniz RC, Jayaraman A, Lee K.

Cell Rep. 2018 Apr 24;23(4):1099-1111. doi: 10.1016/j.celrep.2018.03.109. Erratum in: Cell Rep. 2019 Sep 17;28(12):3285.

8.

Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells.

Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ.

Stem Cells. 2018 Jul;36(7):1004-1019. doi: 10.1002/stem.2822. Epub 2018 Apr 1.

9.

Detection of aryl hydrocarbon receptor agonists in human samples.

Rothhammer V, Borucki DM, Kenison JE, Hewson P, Wang Z, Bakshi R, Sherr DH, Quintana FJ.

Sci Rep. 2018 Mar 21;8(1):4970. doi: 10.1038/s41598-018-23323-4.

10.

Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.

Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC.

Sci Transl Med. 2017 Nov 22;9(417). pii: eaam8475. doi: 10.1126/scitranslmed.aam8475.

11.

Dioxins and related environmental contaminants increase TDP-43 levels.

Ash PEA, Stanford EA, Al Abdulatif A, Ramirez-Cardenas A, Ballance HI, Boudeau S, Jeh A, Murithi JM, Tripodis Y, Murphy GJ, Sherr DH, Wolozin B.

Mol Neurodegener. 2017 May 5;12(1):35. doi: 10.1186/s13024-017-0177-9.

12.

Network-based analysis of transcriptional profiles from chemical perturbations experiments.

Mulas F, Li A, Sherr DH, Monti S.

BMC Bioinformatics. 2017 Mar 23;18(Suppl 5):130. doi: 10.1186/s12859-017-1536-9.

13.

An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER-/PR-/Her2- Human Breast Cancer Cells.

Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Landesman E, Laklouk I, Sarita-Reyes C, Gusenleitner D, Li A, Monti S, Manteiga S, Lee K, Sherr DH.

Mol Pharmacol. 2016 Nov;90(5):674-688. Epub 2016 Aug 29.

14.

A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer.

Chen HR, Sherr DH, Hu Z, DeLisi C.

BMC Med Genomics. 2016 Jul 30;9(1):51. doi: 10.1186/s12920-016-0212-7.

15.

Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development.

Smith BW, Stanford EA, Sherr DH, Murphy GJ.

Stem Cells Int. 2016;2016:2574152. doi: 10.1155/2016/2574152. Epub 2016 Apr 11.

16.

Role for the Aryl Hydrocarbon Receptor and Diverse Ligands in Oral Squamous Cell Carcinoma Migration and Tumorigenesis.

Stanford EA, Ramirez-Cardenas A, Wang Z, Novikov O, Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, Kukuruzinska M, Monti S, Bais MV, Sherr DH.

Mol Cancer Res. 2016 Aug;14(8):696-706. doi: 10.1158/1541-7786.MCR-16-0069. Epub 2016 Apr 29.

17.

The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells.

Stanford EA, Wang Z, Novikov O, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Seldin DC, Murphy GJ, Sherr DH.

BMC Biol. 2016 Mar 16;14:20. doi: 10.1186/s12915-016-0240-y.

18.

Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives.

Grandjean P, Barouki R, Bellinger DC, Casteleyn L, Chadwick LH, Cordier S, Etzel RA, Gray KA, Ha EH, Junien C, Karagas M, Kawamoto T, Paige Lawrence B, Perera FP, Prins GS, Puga A, Rosenfeld CS, Sherr DH, Sly PD, Suk W, Sun Q, Toppari J, van den Hazel P, Walker CL, Heindel JJ.

Endocrinology. 2015 Oct;156(10):3408-15. doi: 10.1210/EN.2015-1350. Epub 2015 Aug 4.

19.

The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia.

Shivanna S, Kolandaivelu K, Shashar M, Belghasim M, Al-Rabadi L, Balcells M, Zhang A, Weinberg J, Francis J, Pollastri MP, Edelman ER, Sherr DH, Chitalia VC.

J Am Soc Nephrol. 2016 Jan;27(1):189-201. doi: 10.1681/ASN.2014121241. Epub 2015 May 27.

20.

In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo.

Parks AJ, Pollastri MP, Hahn ME, Stanford EA, Novikov O, Franks DG, Haigh SE, Narasimhan S, Ashton TD, Hopper TG, Kozakov D, Beglov D, Vajda S, Schlezinger JJ, Sherr DH.

Mol Pharmacol. 2014 Nov;86(5):593-608. doi: 10.1124/mol.114.093369. Epub 2014 Aug 26.

21.

Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

Gusenleitner D, Auerbach SS, Melia T, Gómez HF, Sherr DH, Monti S.

PLoS One. 2014 Jul 24;9(7):e102579. doi: 10.1371/journal.pone.0102579. eCollection 2014.

22.

Identification of cinnabarinic acid as a novel endogenous aryl hydrocarbon receptor ligand that drives IL-22 production.

Lowe MM, Mold JE, Kanwar B, Huang Y, Louie A, Pollastri MP, Wang C, Patel G, Franks DG, Schlezinger J, Sherr DH, Silverstone AE, Hahn ME, McCune JM.

PLoS One. 2014 Feb 3;9(2):e87877. doi: 10.1371/journal.pone.0087877. eCollection 2014.

23.

The role of the aryl hydrocarbon receptor in normal and malignant B cell development.

Sherr DH, Monti S.

Semin Immunopathol. 2013 Nov;35(6):705-16. doi: 10.1007/s00281-013-0390-8. Epub 2013 Aug 13. Review.

24.

Aryl hydrocarbon receptor control of adaptive immunity.

Quintana FJ, Sherr DH.

Pharmacol Rev. 2013 Aug 1;65(4):1148-61. doi: 10.1124/pr.113.007823. Print 2013. Review.

25.

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation.

Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ.

Blood. 2013 Jul 18;122(3):376-85. doi: 10.1182/blood-2012-11-466722. Epub 2013 May 30.

26.

Mechanisms of environmental influence on human autoimmunity: a National Institute of Environmental Health Sciences expert panel workshop.

Selmi C, Leung PS, Sherr DH, Diaz M, Nyland JF, Monestier M, Rose NR, Gershwin ME.

J Autoimmun. 2012 Dec;39(4):272-84. doi: 10.1016/j.jaut.2012.05.007. Epub 2012 Jun 28. Review.

PMID:
22749494
27.

You AhR what you eat?

Lawrence BP, Sherr DH.

Nat Immunol. 2012 Jan 19;13(2):117-9. doi: 10.1038/ni.2213. No abstract available.

PMID:
22261961
28.

Immunoglobulin light chain, Blimp-1 and cytochrome P4501B1 peptides as potential vaccines for AL amyloidosis.

Flies A, Ahmadi T, Parks AJ, Prokaeva T, Weng L, Rolfe SS, Seldin DC, Sherr DH.

Immunol Cell Biol. 2012 May;90(5):528-39. doi: 10.1038/icb.2011.73. Epub 2011 Sep 6.

PMID:
21894172
29.

Parallel imaging microfluidic cytometer.

Ehrlich DJ, McKenna BK, Evans JG, Belkina AC, Denis GV, Sherr DH, Cheung MC.

Methods Cell Biol. 2011;102:49-75. doi: 10.1016/B978-0-12-374912-3.00003-1. Review.

30.

Another important biological function for the aryl hydrocarbon receptor.

Sherr DH.

Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1247-8. doi: 10.1161/ATVBAHA.111.227553. No abstract available.

PMID:
21593454
31.

Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling.

Teague JE, Ryu HY, Kirber M, Sherr DH, Schlezinger JJ.

J Immunol. 2010 Sep 15;185(6):3369-78. doi: 10.4049/jimmunol.0902541. Epub 2010 Aug 18.

32.

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, Burns EJ, Sherr DH, Weiner HL, Kuchroo VK.

Nat Immunol. 2010 Sep;11(9):854-61. doi: 10.1038/ni.1912. Epub 2010 Aug 1.

33.

Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans.

Schlezinger JJ, Bernard PL, Haas A, Grandjean P, Weihe P, Sherr DH.

Environ Health Perspect. 2010 May;118(5):693-8. doi: 10.1289/ehp.0901113.

34.
35.

The active form of human aryl hydrocarbon receptor (AHR) repressor lacks exon 8, and its Pro 185 and Ala 185 variants repress both AHR and hypoxia-inducible factor.

Karchner SI, Jenny MJ, Tarrant AM, Evans BR, Kang HJ, Bae I, Sherr DH, Hahn ME.

Mol Cell Biol. 2009 Jul;29(13):3465-77. doi: 10.1128/MCB.00206-09. Epub 2009 Apr 20.

36.

Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor.

Hahn ME, Allan LL, Sherr DH.

Biochem Pharmacol. 2009 Feb 15;77(4):485-97. doi: 10.1016/j.bcp.2008.09.016. Epub 2008 Sep 20. Review.

37.
38.

NF-kappaB and epithelial to mesenchymal transition of cancer.

Min C, Eddy SF, Sherr DH, Sonenshein GE.

J Cell Biochem. 2008 Jun 1;104(3):733-44. doi: 10.1002/jcb.21695. Review.

PMID:
18253935
39.

Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype.

Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH, Sonenshein GE.

Cancer Res. 2007 Dec 15;67(24):11742-50.

41.

Constitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissue.

Yang X, Solomon S, Fraser LR, Trombino AF, Liu D, Sonenshein GE, Hestermann EV, Sherr DH.

J Cell Biochem. 2008 May 15;104(2):402-17.

PMID:
18059014
42.

Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator.

Evans BR, Karchner SI, Allan LL, Pollenz RS, Tanguay RL, Jenny MJ, Sherr DH, Hahn ME.

Mol Pharmacol. 2008 Feb;73(2):387-98. Epub 2007 Nov 13.

43.

An L-tyrosine derivative and PPARgamma agonist, GW7845, activates a multifaceted caspase cascade in bone marrow B cells.

Schlezinger JJ, Emberley JK, Bissonnette SL, Sherr DH.

Toxicol Sci. 2007 Jul;98(1):125-36. Epub 2007 Mar 30.

PMID:
17400580
44.

A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis.

Schlezinger JJ, Liu D, Farago M, Seldin DC, Belguise K, Sonenshein GE, Sherr DH.

Biol Chem. 2006 Sep;387(9):1175-87. Review.

PMID:
16972784
48.

CYP1A1 in polycyclic aromatic hydrocarbon-induced B lymphocyte growth suppression.

Allan LL, Schlezinger JJ, Shansab M, Sherr DH.

Biochem Biophys Res Commun. 2006 Mar 31;342(1):227-35. Epub 2006 Feb 3.

PMID:
16472762
49.

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors.

Currier N, Solomon SE, Demicco EG, Chang DL, Farago M, Ying H, Dominguez I, Sonenshein GE, Cardiff RD, Xiao ZX, Sherr DH, Seldin DC.

Toxicol Pathol. 2005;33(6):726-37.

PMID:
16263698
50.

The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells.

Yang X, Liu D, Murray TJ, Mitchell GC, Hesterman EV, Karchner SI, Merson RR, Hahn ME, Sherr DH.

Oncogene. 2005 Nov 24;24(53):7869-81.

PMID:
16091746

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