Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 548


Stroke code simulation benefits advanced practice providers similar to neurology residents.

Khan M, Baird GL, Price T, Tubergen T, Kaskar O, De Jesus M, Zachariah J, Oostema A, Scurek R, Coleman RR, Sherman W, Hingtgen C, Abdelhak T, Smith B, Silver B.

Neurol Clin Pract. 2018 Apr;8(2):116-119. doi: 10.1212/CPJ.0000000000000435.


Large-Scale Validation of Mixed-Solvent Simulations to Assess Hotspots at Protein-Protein Interaction Interfaces.

Ghanakota P, van Vlijmen H, Sherman W, Beuming T.

J Chem Inf Model. 2018 Apr 23;58(4):784-793. doi: 10.1021/acs.jcim.7b00487. Epub 2018 Apr 11.


First-in-Human Use of a Retention-Enhanced Catheter for Endomyocardial Cell Delivery.

Sherman W, Bartunek J, Dolatabadi D, Sanz-Ruiz R, Beleslin B, Wojakowski W, Heyndrickx G, Kimpalou JZ, Waldman SA, Laarman GJ, Seron A, Behfar A, Latere JP, Terzic A, Wijns W; CHART Program.

JACC Cardiovasc Interv. 2018 Feb 26;11(4):412-414. doi: 10.1016/j.jcin.2017.10.036. No abstract available.


Autologous CD34+ cell therapy improves exercise capacity, angina frequency and reduces mortality in no-option refractory angina: a patient-level pooled analysis of randomized double-blinded trials.

Henry TD, Losordo DW, Traverse JH, Schatz RA, Jolicoeur EM, Schaer GL, Clare R, Chiswell K, White CJ, Fortuin FD, Kereiakes DJ, Zeiher AM, Sherman W, Hunt AS, Povsic TJ.

Eur Heart J. 2018 Jun 14;39(23):2208-2216. doi: 10.1093/eurheartj/ehx764.


Relative Binding Free Energy Calculations in Drug Discovery: Recent Advances and Practical Considerations.

Cournia Z, Allen B, Sherman W.

J Chem Inf Model. 2017 Dec 26;57(12):2911-2937. doi: 10.1021/acs.jcim.7b00564. Epub 2017 Dec 15.


Predictors of Response and Survival in Locally Advanced Adenocarcinoma of the Pancreas Following Neoadjuvant GTX with or Without Radiation Therapy.

Sherman WH, Hecht E, Leung D, Chu K.

Oncologist. 2018 Jan;23(1):4-e10. doi: 10.1634/theoncologist.2017-0208. Epub 2017 Dec 6.


A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases.

Bertoldo JB, Rodrigues T, Dunsmore L, Aprile FA, Marques MC, Rosado LA, Boutureira O, Steinbrecher TB, Sherman W, Corzana F, Terenzi H, Bernardes GJL.

Chem. 2017 Oct 12;3(4):665-677. doi: 10.1016/j.chempr.2017.07.009.


The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains.

English CA, Sherman W, Meng W, Gierasch LM.

J Biol Chem. 2017 Sep 8;292(36):14765-14774. doi: 10.1074/jbc.M117.789313. Epub 2017 Jul 28.


A Prospective, Randomized, Controlled Trial Comparing the Outpatient Treatment of Pediatric and Adult Partial-Thickness Burns with Suprathel or Mepilex Ag.

Hundeshagen G, Collins VN, Wurzer P, Sherman W, Voigt CD, Cambiaso-Daniel J, Nunez Lopez O, Sheaffer J, Herndon DN, Finnerty CC, Branski LK.

J Burn Care Res. 2018 Feb 20;39(2):261-267. doi: 10.1097/BCR.0000000000000584.


Deciphering Cryptic Binding Sites on Proteins by Mixed-Solvent Molecular Dynamics.

Kimura SR, Hu HP, Ruvinsky AM, Sherman W, Favia AD.

J Chem Inf Model. 2017 Jun 26;57(6):1388-1401. doi: 10.1021/acs.jcim.6b00623. Epub 2017 Jun 8.


Calculating Water Thermodynamics in the Binding Site of Proteins - Applications of WaterMap to Drug Discovery.

Cappel D, Sherman W, Beuming T.

Curr Top Med Chem. 2017;17(23):2586-2598. doi: 10.2174/1568026617666170414141452. Review.


New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment.

Cowie MR, Filippatos GS, Alonso Garcia MLA, Anker SD, Baczynska A, Bloomfield DM, Borentain M, Bruins Slot K, Cronin M, Doevendans PA, El-Gazayerly A, Gimpelewicz C, Honarpour N, Janmohamed S, Janssen H, Kim AM, Lautsch D, Laws I, Lefkowitz M, Lopez-Sendon J, Lyon AR, Malik FI, McMurray JJV, Metra M, Figueroa Perez S, Pfeffer MA, Pocock SJ, Ponikowski P, Prasad K, Richard-Lordereau I, Roessig L, Rosano GMC, Sherman W, Stough WG, Swedberg K, Tyl B, Zannad F, Boulton C, De Graeff P.

Eur J Heart Fail. 2017 Jun;19(6):718-727. doi: 10.1002/ejhf.809. Epub 2017 Mar 27. Review.


Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases.

Filippatos GS, de Graeff P, Bax JJ, Borg JJ, Cleland JG, Dargie HJ, Flather M, Ford I, Friede T, Greenberg B, Henon-Goburdhun C, Holcomb R, Horst B, Lekakis J, Mueller-Velten G, Papavassiliou AG, Prasad K, Rosano GM, Severin T, Sherman W, Stough WG, Swedberg K, Tavazzi L, Tousoulis D, Vardas P, Ruschitzka F, Anker SD.

Eur J Heart Fail. 2017 Apr;19(4):449-456. doi: 10.1002/ejhf.761. Epub 2017 Mar 8. Review.


Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.

Fox JM, Kang K, Sastry M, Sherman W, Sankaran B, Zwart PH, Whitesides GM.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3833-3837. doi: 10.1002/anie.201609409. Epub 2017 Mar 2.


Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial.

Bartunek J, Terzic A, Davison BA, Filippatos GS, Radovanovic S, Beleslin B, Merkely B, Musialek P, Wojakowski W, Andreka P, Horvath IG, Katz A, Dolatabadi D, El Nakadi B, Arandjelovic A, Edes I, Seferovic PM, Obradovic S, Vanderheyden M, Jagic N, Petrov I, Atar S, Halabi M, Gelev VL, Shochat MK, Kasprzak JD, Sanz-Ruiz R, Heyndrickx GR, Nyolczas N, Legrand V, Guédès A, Heyse A, Moccetti T, Fernandez-Aviles F, Jimenez-Quevedo P, Bayes-Genis A, Hernandez-Garcia JM, Ribichini F, Gruchala M, Waldman SA, Teerlink JR, Gersh BJ, Povsic TJ, Henry TD, Metra M, Hajjar RJ, Tendera M, Behfar A, Alexandre B, Seron A, Stough WG, Sherman W, Cotter G, Wijns W; CHART Program.

Eur Heart J. 2017 Mar 1;38(9):648-660. doi: 10.1093/eurheartj/ehw543.


Relative Binding Free Energy Calculations Applied to Protein Homology Models.

Cappel D, Hall ML, Lenselink EB, Beuming T, Qi J, Bradner J, Sherman W.

J Chem Inf Model. 2016 Dec 27;56(12):2388-2400. doi: 10.1021/acs.jcim.6b00362. Epub 2016 Nov 18.


Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability-Large-Scale Validation of MD-Based Relative Free Energy Calculations.

Steinbrecher T, Zhu C, Wang L, Abel R, Negron C, Pearlman D, Feyfant E, Duan J, Sherman W.

J Mol Biol. 2017 Apr 7;429(7):948-963. doi: 10.1016/j.jmb.2016.12.007. Epub 2016 Dec 10.


Automated Protocol for Large-Scale Modeling of Gene Expression Data.

Hall ML, Calkins D, Sherman W.

J Chem Inf Model. 2016 Nov 28;56(11):2216-2224. Epub 2016 Nov 10.


In search of novel ligands using a structure-based approach: a case study on the adenosine A2A receptor.

Lenselink EB, Beuming T, van Veen C, Massink A, Sherman W, van Vlijmen HW, IJzerman AP.

J Comput Aided Mol Des. 2016 Oct;30(10):863-874. Epub 2016 Sep 15.


Molecular dynamics techniques for modeling G protein-coupled receptors.

McRobb FM, Negri A, Beuming T, Sherman W.

Curr Opin Pharmacol. 2016 Oct;30:69-75. doi: 10.1016/j.coph.2016.07.001. Epub 2016 Aug 3. Review.


Immersive Molecular Visualization with Omnidirectional Stereoscopic Ray Tracing and Remote Rendering.

Stone JE, Sherman WR, Schulten K.

IEEE Int Symp Parallel Distrib Process Workshops Phd Forum. 2016 May;2016:1048-1057. Epub 2016 Aug 4.


AutoQSAR: an automated machine learning tool for best-practice quantitative structure-activity relationship modeling.

Dixon SL, Duan J, Smith E, Von Bargen CD, Sherman W, Repasky MP.

Future Med Chem. 2016 Oct;8(15):1825-1839. Epub 2016 Sep 19.


Predicting Binding Affinities for GPCR Ligands Using Free-Energy Perturbation.

Lenselink EB, Louvel J, Forti AF, van Veldhoven JPD, de Vries H, Mulder-Krieger T, McRobb FM, Negri A, Goose J, Abel R, van Vlijmen HWT, Wang L, Harder E, Sherman W, IJzerman AP, Beuming T.

ACS Omega. 2016 Aug 31;1(2):293-304. doi: 10.1021/acsomega.6b00086. Epub 2016 Aug 30.


Institutional Improvement in Weight Loss after Laparoscopic Sleeve Gastrectomy.

Mangieri CW, Strode MA, Sherman WE, Pierotti ML, Faler BJ, Choi YU.

Am Surg. 2016 May;82(5):448-55.


Differential Water Thermodynamics Determine PI3K-Beta/Delta Selectivity for Solvent-Exposed Ligand Modifications.

Robinson D, Bertrand T, Carry JC, Halley F, Karlsson A, Mathieu M, Minoux H, Perrin MA, Robert B, Schio L, Sherman W.

J Chem Inf Model. 2016 May 23;56(5):886-94. doi: 10.1021/acs.jcim.5b00641. Epub 2016 May 4.


The Recipe for Protein Sequence-Based Function Prediction and Its Implementation in the ANNOTATOR Software Environment.

Eisenhaber B, Kuchibhatla D, Sherman W, Sirota FL, Berezovsky IN, Wong WC, Eisenhaber F.

Methods Mol Biol. 2016;1415:477-506. doi: 10.1007/978-1-4939-3572-7_25.


11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Fechner U, de Graaf C, Torda AE, Güssregen S, Evers A, Matter H, Hessler G, Richmond NJ, Schmidtke P, Segler MHS, Waller MP, Pleik S, Shea JE, Levine Z, Mullen R, van den Broek K, Epple M, Kuhn H, Truszkowski A, Zielesny A, Fraaije JH, Gracia RS, Kast SM, Bulusu KC, Bender A, Yosipof A, Nahum O, Senderowitz H, Krotzky T, Schulz R, Wolber G, Bietz S, Rarey M, Zimmermann MO, Lange A, Ruff M, Heidrich J, Onlia I, Exner TE, Boeckler FM, Bermudez M, Firaha DS, Hollóczki O, Kirchner B, Tautermann CS, Volkamer A, Eid S, Turk S, Rippmann F, Fulle S, Saleh N, Saladino G, Gervasio FL, Haensele E, Banting L, Whitley DC, Oliveira Santos JS, Bureau R, Clark T, Sandmann A, Lanig H, Kibies P, Heil J, Hoffgaard F, Frach R, Engel J, Smith S, Basu D, Rauh D, Kohlbacher O, Boeckler FM, Essex JW, Bodnarchuk MS, Ross GA, Finkelmann AR, Göller AH, Schneider G, Husch T, Schütter C, Balducci A, Korth M, Ntie-Kang F, Günther S, Sippl W, Mbaze LM, Ntie-Kang F, Simoben CV, Lifongo LL, Ntie-Kang F, Judson P, Barilla J, Lokajíček MV, Pisaková H, Simr P, Kireeva N, Petrov A, Ostroumov D, Solovev VP, Pervov VS, Friedrich NO, Sommer K, Rarey M, Kirchmair J, Proschak E, Weber J, Moser D, Kalinowski L, Achenbach J, Mackey M, Cheeseright T, Renner G, Renner G, Schmidt TC, Schram J, Egelkraut-Holtus M, van Oeyen A, Kalliokoski T, Fourches D, Ibezim A, Mbah CJ, Adikwu UM, Nwodo NJ, Steudle A, Masek BB, Nagy S, Baker D, Soltanshahi F, Dorfman R, Dubrucq K, Patel H, Koch O, Mrugalla F, Kast SM, Ain QU, Fuchs JE, Owen RM, Omoto K, Torella R, Pryde DC, Glen R, Bender A, Hošek P, Spiwok V, Mervin LH, Barrett I, Firth M, Murray DC, McWilliams L, Cao Q, Engkvist O, Warszycki D, Śmieja M, Bojarski AJ, Aniceto N, Freitas A, Ghafourian T, Herrmann G, Eigner-Pitto V, Naß A, Kurczab R, Bojarski AJ, Lange A, Günther MB, Hennig S, Büttner FM, Schall C, Sievers-Engler A, Ansideri F, Koch P, Stehle T, Laufer S, Böckler FM, Zdrazil B, Montanari F, Ecker GF, Grebner C, Hogner A, Ulander J, Edman K, Guallar V, Tyrchan C, Ulander J, Tyrchan C, Klute W, Bergström F, Kramer C, Nguyen QD, Frach R, Kibies P, Strohfeldt S, Böttcher S, Pongratz T, Horinek D, Kast SM, Rupp B, Al-Yamori R, Lisurek M, Kühne R, Furtado F, van den Broek K, Wessjohann L, Mathea M, Baumann K, Mohamad-Zobir SZ, Fu X, Fan TP, Bender A, Kuhn MA, Sotriffer CA, Zoufir A, Li X, Mervin L, Berg E, Polokoff M, Ihlenfeldt WD, Ihlenfeldt WD, Pretzel J, Alhalabi Z, Fraczkiewicz R, Waldman M, Clark RD, Shaikh N, Garg P, Kos A, Himmler HJ, Sandmann A, Jardin C, Sticht H, Steinbrecher TB, Dahlgren M, Cappel D, Lin T, Wang L, Krilov G, Abel R, Friesner R, Sherman W, Pöhner IA, Panecka J, Wade RC, Bietz S, Schomburg KT, Hilbig M, Rarey M, Jäger C, Wieczorek V, Westerhoff LM, Borbulevych OY, Demuth HU, Buchholz M, Schmidt D, Rickmeyer T, Krotzky T, Kolb P, Mittal S, Sánchez-García E, Nogueira MS, Oliveira TB, da Costa FB, Schmidt TJ.

J Cheminform. 2016 Apr 26;8(Suppl 1):18. doi: 10.1186/s13321-016-0119-5. No abstract available.


Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia.

Kibbe MR, Hirsch AT, Mendelsohn FO, Davies MG, Pham H, Saucedo J, Marston W, Pyun WB, Min SK, Peterson BG, Comerota A, Choi D, Ballard J, Bartow RA, Losordo DW, Sherman W, Driver V, Perin EC.

Gene Ther. 2016 Apr;23(4):399. doi: 10.1038/gt.2016.9. No abstract available.


Highly efficient implementation of pseudospectral time-dependent density-functional theory for the calculation of excitation energies of large molecules.

Cao Y, Hughes T, Giesen D, Halls MD, Goldberg A, Vadicherla TR, Sastry M, Patel B, Sherman W, Weisman AL, Friesner RA.

J Comput Chem. 2016 Jun 15;37(16):1425-41. doi: 10.1002/jcc.24350. Epub 2016 Mar 25.


Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial design.

Bartunek J, Davison B, Sherman W, Povsic T, Henry TD, Gersh B, Metra M, Filippatos G, Hajjar R, Behfar A, Homsy C, Cotter G, Wijns W, Tendera M, Terzic A.

Eur J Heart Fail. 2016 Feb;18(2):160-8. doi: 10.1002/ejhf.434. Epub 2015 Dec 14.


Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia.

Kibbe MR, Hirsch AT, Mendelsohn FO, Davies MG, Pham H, Saucedo J, Marston W, Pyun WB, Min SK, Peterson BG, Comerota A, Choi D, Ballard J, Bartow RA, Losordo DW, Sherman W, Driver V, Perin EC.

Gene Ther. 2016 Mar;23(3):306-12. doi: 10.1038/gt.2015.110. Epub 2015 Dec 8. Erratum in: Gene Ther. 2016 Apr;23(4):399.


Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins.

Kamps JJ, Huang J, Poater J, Xu C, Pieters BJ, Dong A, Min J, Sherman W, Beuming T, Matthias Bickelhaupt F, Li H, Mecinović J.

Nat Commun. 2015 Nov 18;6:8911. doi: 10.1038/ncomms9911.


Randomized trial of OFIRMEV versus placebo for pain management after laparoscopic sleeve gastrectomy.

Strode MA, Sherman W, Mangieri CW, Bland CM, Sparks PJ, Faler BJ, Prasad BM, Choi YU.

Surg Obes Relat Dis. 2016 May;12(4):772-777. doi: 10.1016/j.soard.2015.08.512. Epub 2015 Aug 29.


HPMV: human protein mutation viewer - relating sequence mutations to protein sequence architecture and function changes.

Sherman WA, Kuchibhatla DB, Limviphuvadh V, Maurer-Stroh S, Eisenhaber B, Eisenhaber F.

J Bioinform Comput Biol. 2015 Oct;13(5):1550028. doi: 10.1142/S0219720015500286. Epub 2015 Oct 27.


Accurate Binding Free Energy Predictions in Fragment Optimization.

Steinbrecher TB, Dahlgren M, Cappel D, Lin T, Wang L, Krilov G, Abel R, Friesner R, Sherman W.

J Chem Inf Model. 2015 Nov 23;55(11):2411-20. doi: 10.1021/acs.jcim.5b00538. Epub 2015 Oct 21.


Does Preoperative Weight Change Predict Postoperative Weight Loss After Laparoscopic Sleeve Gastrectomy?

Sherman WE, Lane AE, Mangieri CW, Choi YU, Faler BJ.

Bariatr Surg Pract Patient Care. 2015 Sep 1;10(3):126-129.


Fludarabine in the Treatment of Refractory Chronic Inflammatory Demyelinating Neuropathies.

Leitch MM, Sherman WH, Brannagan TH 3rd.

J Clin Neuromuscul Dis. 2015 Sep;17(1):1-5. doi: 10.1097/CND.0000000000000083.


Docking and Virtual Screening Strategies for GPCR Drug Discovery.

Beuming T, Lenselink B, Pala D, McRobb F, Repasky M, Sherman W.

Methods Mol Biol. 2015;1335:251-76. doi: 10.1007/978-1-4939-2914-6_17.


Percutaneous Fluoroscopic-Guided Endomyocardial Delivery in an Experimental Model of Left Ventricular Assist Device Support.

Dalén M, Behfar A, Terzic A, Schiller P, Seron A, Sherman W, Månsson-Broberg A, Grinnemo KH.

J Cardiovasc Transl Res. 2015 Aug;8(6):381-4. doi: 10.1007/s12265-015-9642-4. Epub 2015 Jul 7.


Interactions between Hofmeister anions and the binding pocket of a protein.

Fox JM, Kang K, Sherman W, Héroux A, Sastry GM, Baghbanzadeh M, Lockett MR, Whitesides GM.

J Am Chem Soc. 2015 Mar 25;137(11):3859-66. doi: 10.1021/jacs.5b00187. Epub 2015 Mar 17.


Multivessel spontaneous coronary artery dissection with angiographic documentation before and after the acute event.

Matsumura M, Mintz GS, Green P, Fall KN, Sherman W, Dizon JM, Maehara A.

Coron Artery Dis. 2015 Jun;26(4):361-3. doi: 10.1097/MCA.0000000000000226. No abstract available.


Racial disparity in survival from early breast cancer in the department of defense healthcare system.

Rizzo JA, Sherman WE, Arciero CA.

J Surg Oncol. 2015 Jun;111(7):819-23. doi: 10.1002/jso.23884. Epub 2015 Feb 24.


Accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free-energy calculation protocol and force field.

Wang L, Wu Y, Deng Y, Kim B, Pierce L, Krilov G, Lupyan D, Robinson S, Dahlgren MK, Greenwood J, Romero DL, Masse C, Knight JL, Steinbrecher T, Beuming T, Damm W, Harder E, Sherman W, Brewer M, Wester R, Murcko M, Frye L, Farid R, Lin T, Mobley DL, Jorgensen WL, Berne BJ, Friesner RA, Abel R.

J Am Chem Soc. 2015 Feb 25;137(7):2695-703. doi: 10.1021/ja512751q. Epub 2015 Feb 12.


Neoadjuvant gemcitabine, docetaxel, and capecitabine followed by gemcitabine and capecitabine/radiation therapy and surgery in locally advanced, unresectable pancreatic adenocarcinoma.

Sherman WH, Chu K, Chabot J, Allendorf J, Schrope BA, Hecht E, Jin B, Leung D, Remotti H, Addeo G, Postolov I, Tsai W, Fine RL.

Cancer. 2015 Mar 1;121(5):673-80. doi: 10.1002/cncr.29112. Epub 2014 Dec 9.


Exploring conformational search protocols for ligand-based virtual screening and 3-D QSAR modeling.

Cappel D, Dixon SL, Sherman W, Duan J.

J Comput Aided Mol Des. 2015 Feb;29(2):165-82. doi: 10.1007/s10822-014-9813-4. Epub 2014 Nov 19.


Improving docking results via reranking of ensembles of ligand poses in multiple X-ray protein conformations with MM-GBSA.

Greenidge PA, Kramer C, Mozziconacci JC, Sherman W.

J Chem Inf Model. 2014 Oct 27;54(10):2697-717. doi: 10.1021/ci5003735. Epub 2014 Sep 30.


Mechanistic and computational studies of the reductive half-reaction of tyrosine to phenylalanine active site variants of D-arginine dehydrogenase.

Gannavaram S, Sirin S, Sherman W, Gadda G.

Biochemistry. 2014 Oct 21;53(41):6574-83. doi: 10.1021/bi500917q. Epub 2014 Oct 7.


Physics-based enzyme design: predicting binding affinity and catalytic activity.

Sirin S, Pearlman DA, Sherman W.

Proteins. 2014 Dec;82(12):3397-409. doi: 10.1002/prot.24694. Epub 2014 Oct 30.


McCay ("Mac") Vernon (1928-2013).

Sherman WA.

Am Psychol. 2014 Sep;69(6):624. doi: 10.1037/a0037283.


Acquired cutis laxa associated with heavy chain deposition disease involving dermal elastic fibers.

O'Malley JT, D'Agati VD, Sherman WH, Grossman ME.

JAMA Dermatol. 2014 Nov;150(11):1192-6. doi: 10.1001/jamadermatol.2014.725.


Supplemental Content

Loading ...
Support Center