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Items: 29

1.

Knockdown of CDK2AP1 in human embryonic stem cells reduces the threshold of differentiation.

Alsayegh KN, Sheridan SD, Iyer S, Rao RR.

PLoS One. 2018 May 7;13(5):e0196817. doi: 10.1371/journal.pone.0196817. eCollection 2018.

2.

Combinatorial programming of human neuronal progenitors using magnetically-guided stoichiometric mRNA delivery.

Azimi SM, Sheridan SD, Ghannad-Rezaie M, Eimon PM, Yanik MF.

Elife. 2018 May 1;7. pii: e31922. doi: 10.7554/eLife.31922.

3.

Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):791. doi: 10.1038/mp.2018.5. No abstract available.

PMID:
29565043
4.

Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.

Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, Haggarty SJ, Tsai LH.

J Neurosci. 2017 Oct 11;37(41):9917-9924. doi: 10.1523/JNEUROSCI.0621-17.2017. Epub 2017 Sep 14.

5.

WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4.

Hennig KM, Fass DM, Zhao WN, Sheridan SD, Fu T, Erdin S, Stortchevoi A, Lucente D, Cody JD, Sweetser D, Gusella JF, Talkowski ME, Haggarty SJ.

Mol Neuropsychiatry. 2017 Jul;3(1):53-71. doi: 10.1159/000475666. Epub 2017 Jul 14.

6.

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.

Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY.

Proc Natl Acad Sci U S A. 2017 May 30;114(22):E4462-E4471. doi: 10.1073/pnas.1700111114. Epub 2017 May 12.

7.

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):1051-1065. doi: 10.1038/mp.2017.86. Epub 2017 Apr 25.

8.

Patient-specific models of microglia-mediated engulfment of synapses and neural progenitors.

Sellgren CM, Sheridan SD, Gracias J, Xuan D, Fu T, Perlis RH.

Mol Psychiatry. 2017 Feb;22(2):170-177. doi: 10.1038/mp.2016.220. Epub 2016 Dec 13.

9.

Noncoding RNAs connect genetic risk factors to the neurodevelopmental basis of bipolar disorder.

Bavamian S, Mellios N, Lalonde J, Fass DM, Wang J, Sheridan SD, Madison JM, Zhou F, Rueckert EH, Barker D, Perlis RH, Sur M, Haggarty SJ.

Mol Psychiatry. 2015 May;20(5):548. doi: 10.1038/mp.2015.51. No abstract available.

10.

Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities.

Madison JM, Zhou F, Nigam A, Hussain A, Barker DD, Nehme R, van der Ven K, Hsu J, Wolf P, Fleishman M, O'Dushlaine C, Rose S, Chambert K, Lau FH, Ahfeldt T, Rueckert EH, Sheridan SD, Fass DM, Nemesh J, Mullen TE, Daheron L, McCarroll S, Sklar P, Perlis RH, Haggarty SJ.

Mol Psychiatry. 2015 Jun;20(6):703-17. doi: 10.1038/mp.2015.7. Epub 2015 Mar 3.

11.

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.

Bavamian S, Mellios N, Lalonde J, Fass DM, Wang J, Sheridan SD, Madison JM, Zhou F, Rueckert EH, Barker D, Perlis RH, Sur M, Haggarty SJ.

Mol Psychiatry. 2015 May;20(5):573-84. doi: 10.1038/mp.2014.176. Epub 2015 Jan 27.

12.

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.

Sugathan A, Biagioli M, Golzio C, Erdin S, Blumenthal I, Manavalan P, Ragavendran A, Brand H, Lucente D, Miles J, Sheridan SD, Stortchevoi A, Kellis M, Haggarty SJ, Katsanis N, Gusella JF, Talkowski ME.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4468-77. doi: 10.1073/pnas.1405266111. Epub 2014 Oct 7.

13.

β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome.

Mellios N, Woodson J, Garcia RI, Crawford B, Sharma J, Sheridan SD, Haggarty SJ, Sur M.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9947-52. doi: 10.1073/pnas.1309426111. Epub 2014 Jun 23.

14.

Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.

Lojewski X, Staropoli JF, Biswas-Legrand S, Simas AM, Haliw L, Selig MK, Coppel SH, Goss KA, Petcherski A, Chandrachud U, Sheridan SD, Lucente D, Sims KB, Gusella JF, Sondhi D, Crystal RG, Reinhardt P, Sterneckert J, Schöler H, Haggarty SJ, Storch A, Hermann A, Cotman SL.

Hum Mol Genet. 2014 Apr 15;23(8):2005-22. doi: 10.1093/hmg/ddt596. Epub 2013 Nov 23.

15.

A high-throughput screen for Wnt/β-catenin signaling pathway modulators in human iPSC-derived neural progenitors.

Zhao WN, Cheng C, Theriault KM, Sheridan SD, Tsai LH, Haggarty SJ.

J Biomol Screen. 2012 Oct;17(9):1252-63. Epub 2012 Aug 24.

16.

Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder.

Rueckert EH, Barker D, Ruderfer D, Bergen SE, O'Dushlaine C, Luce CJ, Sheridan SD, Theriault KM, Chambert K, Moran J, Purcell SM, Madison JM, Haggarty SJ, Sklar P.

Mol Psychiatry. 2013 Aug;18(8):922-9. doi: 10.1038/mp.2012.104. Epub 2012 Jul 31.

17.

Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes.

Anguera MC, Sadreyev R, Zhang Z, Szanto A, Payer B, Sheridan SD, Kwok S, Haggarty SJ, Sur M, Alvarez J, Gimelbrant A, Mitalipova M, Kirby JE, Lee JT.

Cell Stem Cell. 2012 Jul 6;11(1):75-90. doi: 10.1016/j.stem.2012.03.008.

18.

Analysis of embryoid bodies derived from human induced pluripotent stem cells as a means to assess pluripotency.

Sheridan SD, Surampudi V, Rao RR.

Stem Cells Int. 2012;2012:738910. doi: 10.1155/2012/738910. Epub 2012 Mar 1.

19.

PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation.

Hewitt KJ, Shamis Y, Knight E, Smith A, Maione A, Alt-Holland A, Sheridan SD, Haggarty SJ, Garlick JA.

J Cell Sci. 2012 May 1;125(Pt 9):2276-87. doi: 10.1242/jcs.099192. Epub 2012 Feb 17.

20.

Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome.

Sheridan SD, Theriault KM, Reis SA, Zhou F, Madison JM, Daheron L, Loring JF, Haggarty SJ.

PLoS One. 2011;6(10):e26203. doi: 10.1371/journal.pone.0026203. Epub 2011 Oct 12.

21.

Stable propagation of human embryonic and induced pluripotent stem cells on decellularized human substrates.

Abraham S, Sheridan SD, Miller B, Rao RR.

Biotechnol Prog. 2010 Jul-Aug;26(4):1126-34. doi: 10.1002/btpr.412.

PMID:
20730767
22.

Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system.

Abraham S, Sheridan SD, Laurent LC, Albert K, Stubban C, Ulitsky I, Miller B, Loring JF, Rao RR.

Biochem Biophys Res Commun. 2010 Mar 5;393(2):211-6. doi: 10.1016/j.bbrc.2010.01.101. Epub 2010 Feb 1.

23.

A chemical compound that stimulates the human homologous recombination protein RAD51.

Jayathilaka K, Sheridan SD, Bold TD, Bochenska K, Logan HL, Weichselbaum RR, Bishop DK, Connell PP.

Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15848-53. doi: 10.1073/pnas.0808046105. Epub 2008 Oct 7.

24.

A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments.

Sheridan SD, Yu X, Roth R, Heuser JE, Sehorn MG, Sung P, Egelman EH, Bishop DK.

Nucleic Acids Res. 2008 Jul;36(12):4057-66. doi: 10.1093/nar/gkn352. Epub 2008 Jun 4.

25.

Microporous membrane growth substrates for embryonic stem cell culture and differentiation.

Sheridan SD, Gil S, Wilgo M, Pitt A.

Methods Cell Biol. 2008;86:29-57. doi: 10.1016/S0091-679X(08)00003-4.

PMID:
18442643
26.

Activation and repression of transcription initiation by a distant DNA structural transition.

Sheridan SD, Opel ML, Hatfield GW.

Mol Microbiol. 2001 May;40(3):684-90.

27.

Inhibition of DNA supercoiling-dependent transcriptional activation by a distant B-DNA to Z-DNA transition.

Sheridan SD, Benham CJ, Hatfield GW.

J Biol Chem. 1999 Mar 19;274(12):8169-74.

29.

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